| Recruiting | Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease Sjogren's Syndrome | Phase 2 | 2025-12-18 |
| Completed | PTH-independent Effects of Encaleret Post-Surgical Hypoparathyroidism | Phase 2 | 2023-09-01 |
| Completed | Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia Fibrous Dysplasia Of Bone | Phase 2 | 2022-12-07 |
| Completed | Study of Denosumab for Prevention of Skeletal Disease Progression in Children With Fibrous Dysplasia Fibrous Dysplasia | Phase 2 | 2022-10-12 |
| Active Not Recruiting | Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome Sjogren's Syndrome | Phase 1 / Phase 2 | 2021-05-18 |
| Completed | Transmissibility and Viral Load of SARS-CoV-2 in Oral Secretions COVID-19 | — | 2020-04-16 |
| Active Not Recruiting | Denosumab Treatment for Fibrous Dysplasia Bone Diseases, Pain | Phase 2 | 2019-06-13 |
| Terminated | BGJ398 for the Treatment of Tumor-Induced Osteomalacia Tumor-Induced Osteomalacia, Oncogenic Osteomalacia | Phase 2 | 2019-02-27 |
| Recruiting | Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Graft Versus Host Disease | — | 2018-11-15 |
| Completed | Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Voluntee Sjogren's Syndrome, Oral Health | — | 2018-05-01 |
| Recruiting | Natural History of Craniofacial Anomalies and Developmental Growth Variants Prognathism, Retrognathism, Dentofacial Deformities | — | 2016-04-18 |
| Recruiting | Characterization of Diseases With Salivary Gland Involvement Healthy Volunteer, Sjogren's Syndrome, Salivary Gland Disease | — | 2015-04-03 |
| Recruiting | Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal Stomatognatic, Tooth Diseases, Diseases | — | 2013-06-19 |
| Completed | Bacterial Arrangement on the Teeth Dental Plaque, Oral Health, Periodontal Disease and Caries | — | 2013-01-16 |
| Terminated | Cinacalcet for Fibroblast Growth Factor 23 (FGF23)-Mediated Hypophosphatemia (Hypophosphatemic Rickets) Osteomalacia | Phase 1 | 2012-11-16 |
| Recruiting | Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis) Immunosuppression, Periodontal Disease, Healthy Subjects | — | 2012-10-05 |
| Recruiting | The Pathogenesis and Natural History of Sjogren's Disease Sjogren's Syndrome, Salivary Gland, Pathogenesis | — | 2012-01-18 |
| Terminated | Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome Subjects Sjögren's Syndrome, Xerostomia | Phase 2 | 2011-05-01 |
| Withdrawn | A Comparative Feasibility Study to Assess the Prevalence and Severity of Dental Caries in Incarcerated People Substance-Related Disorders, Dental Caries | — | 2010-09-01 |
| Completed | Rapamycin Therapy in Head and Neck Squamous Cell Carcinoma Mouth Neoplasms, Head and Neck Neoplasms, Tongue Neoplasms | Phase 1 / Phase 2 | 2010-08-01 |
| Completed | The Molecular Anatomy of Oral Wound Healing Wounds and Injuries, Wound Healing, Ulcer | — | 2010-02-02 |
| Recruiting | Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer Intractable Pain, Palliative Care | Phase 1 | 2009-08-14 |
| Terminated | Collection of Tissue Specimens for Analysis and Establishment of Cell Cultures Bone Diseases, Connective Tissue Diseases | — | 2008-12-02 |
| Completed | Evaluation of the Role of the Autonomic Nervous System in Sj(SqrRoot)(Delta)Gren s Syndrome Sjogren's Syndrome, Dysautonomia | — | 2007-11-26 |
| Terminated | Procurement of Tissue Samples for Cell Cultures and Analyses Bone Regeneration, Fracture Healing, Cell Culture Techniques | — | 2007-01-29 |
| Terminated | Effects of PTH Replacement on Bone in Hypoparathyroidism Hypoparathyroidism, DiGeorge Syndrome | Phase 3 | 2006-10-30 |
| Completed | Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer Parotid Salivary Dysfunction | Phase 1 | 2006-09-01 |
| Completed | Physiologic Regulation of FGF-23 Hypoparathyroidism | — | 2006-07-19 |
| Terminated | Pilot Study of Raptiva to Treat Sjogren's Syndrome Sjogren's Syndrome | Phase 2 | 2006-06-01 |
| Completed | Diagnosis, Evaluation and Treatment of Patients in Need of Third Molar Removal Wisdom Teeth | — | 2006-04-14 |
| Completed | Dexamethasone to Treat Oral Lichen Planus Oral Lichen Planus | Phase 2 | 2005-05-01 |
| Completed | Genes Associated With Hereditary and Drug-Induced Gingival Overgrowth Gingival Overgrowth | — | 2005-02-15 |
| Completed | Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral Lichen Planus Lichen Planus, Oral | Phase 2 | 2005-01-01 |
| Completed | Stereo Photogrammetry Imaging in Normal Volunteers and Patients With Head and Facial Malformations Craniofacial Abnormalities | — | 2004-12-21 |
| Completed | Salivary Proteins in Disease and Health Diabetes Mellitus, Sarcoidosis, Dental Caries | — | 2004-12-21 |
| Completed | Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic Osteomal Osteomalacia, Neoplasms | — | 2004-12-15 |
| Completed | Collection of Dental Plaque and Saliva for Studies of Bacterial Colonization of Teeth Healthy | — | 2004-12-02 |
| Completed | Clinical Research Core Dental Screening Protocol Oral Mucosal Disease | — | 2004-09-01 |
| Completed | Levels of Bisphenol A in Urine and Saliva Following Placement of Composite Restorations Dental Restorations | — | 2004-07-26 |
| Completed | Capsaicin to Control Pain Following Third Molar Extraction Healthy, Tooth Extraction | Phase 2 | 2004-07-01 |
| Completed | Pain Pathways in the Brain Healthy, Tooth Extraction | Phase 2 | 2004-02-01 |
| Completed | Prostanoid Levels After Medication to Prevent Pain Following Third Molar (Wisdom Tooth) Extraction Healthy, Tooth Extraction | Phase 2 | 2004-02-01 |
| Completed | Synvisc to Treat Osteoarthritis of the Temporomandibular Joint Osteoarthritis | Phase 2 | 2004-02-01 |
| Completed | Studying Phosphorus Metabolism Phosphorus Metabolism | — | 2003-08-01 |
| Completed | Chemical and Genetic Effects of the Experimental Anti-Cancer Drugs in Cheek Cells in Cancer Patients Cancer | Phase 1 | 2003-02-01 |
| Completed | Rofecoxib and Bupivacaine to Prevent Pain After Third Molar (Wisdom Tooth) Extraction Pain, Tooth Extraction | Phase 2 | 2002-12-01 |
| Completed | Study of Oral Bacteria in Patients With Dry Mouth Xerostomia, Autoimmune Diseases | — | 2002-11-01 |
| Completed | Magnets in the Treatment of Sciatica Low Back Pain, Sciatica | Phase 2 | 2002-08-01 |
| Recruiting | A Natural History Study of Bone and Mineral Disorders Tumor Induced Osteomalcia, Osteomalacia, Familial Tumoral Calcinosis | — | 2001-11-19 |
| Completed | Rofecoxib to Prevent Pain After Third Molar (Wisdom Tooth) Extraction Pain | Phase 2 | 2001-11-01 |
| Completed | Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek Cells Graft vs Host Disease, Sjogren's Syndrome | — | 2001-09-01 |
| Completed | A Study of the Effects of Pegvisomant on Growth Hormone Excess in McCune-Albright Syndrome McCune Albright Syndrome, Polyostotic Fibrous Dysplasia | Phase 3 | 2001-06-01 |
| Completed | Pain Evaluation and Treatment Pain | — | 2001-02-15 |
| Completed | Topiramate in the Treatment of Sciatica Sciatica | Phase 2 | 2001-02-01 |
| Completed | Pain Treatment for Sciatica Radiculopathy, Sciatica | Phase 2 | 2001-01-30 |
| Completed | Capsaicin to Control Pain Following Third Molar Extraction Facial Pain | Phase 2 | 2001-01-01 |
| Completed | Pathophysiology of Chronic Wounds Healthy, Skin Ulcer | — | 2000-10-01 |
| Completed | Effects of Letrozole on Precocious Puberty Due to McCune Albright Syndrome McCune Albright Syndrome, Polyostotic Fibrous Dysplasia, Precocious Puberty | Phase 1 | 2000-08-03 |
| Completed | Cyclooxygenase Levels Following Surgery to Remove Third Molars (Wisdom Teeth) Healthy, Inflammation | — | 2000-08-01 |
| Completed | Etanercept (Enbrel) to Treat Pain and Swelling After Third Molar Extraction Healthy, Inflammation | Phase 2 | 2000-07-01 |
| Completed | Effects of Topical SLPI on Skin Wounds Healthy, Wound Healing | Phase 1 | 2000-04-01 |
| Completed | Oral Manifestations of Aplastic Anemia Aplastic Anemia | — | 2000-04-01 |
| Completed | Influence of Genetics in Pain Sensitivity Healthy, Hyperalgesia, Pain | Phase 2 | 2000-01-01 |
| Completed | Eligibility Screening for National Institute of Dental and Craniofacial Research Studies Fibromyalgia | — | 2000-01-01 |
| Completed | Etanercept Therapy for Sjogren's Syndrome Sjogren's Syndrome | Phase 2 | 1999-12-01 |
| Completed | Study of Etanercept and Celecoxib to Treat Temporomandibular Disorders (Painful Joint Conditions) Temporomandibular Joint Disorder | Phase 2 | 1999-12-01 |
| Completed | Celebrex for Pain Relief After Oral Surgery Facial Pain | Phase 2 | 1999-12-01 |
| Completed | Using a Narcotic to Enhance the Numbing Effect of the Local Anesthetic Lidocaine on Inflamed Molar Teeth Healthy, Inflammation, Mouth Disease | — | 1999-11-01 |
| Completed | The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy Volunteers Sjogren's Syndrome | — | 1999-11-01 |
| Completed | Natural History of Salivary Gland Dysfunction and Sjogren's Syndrome Lymphoma, Salivary Gland Disease, Sjogren's Syndrome | — | 1999-04-09 |
| Completed | Bone Marrow Injection to Replace Diseased Bone in Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome Polyostotic Fibrous Dysplasia | — | 1998-12-15 |
| Recruiting | Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome McCune-Albright Syndrome | — | 1998-12-13 |
| Completed | Alendronate to Treat Polyostotic Fibrous Dysplasia and McCune-Albright Syndrome Polyostotic Fibrous Dysplasia | Phase 2 | 1998-08-24 |
| Completed | Study of the Composition of Dental Plaque Dental Caries, Dental Plaque, Periodontal Disease | — | 1998-06-19 |
| Completed | Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain Facial Neuralgia, Pain, Trigeminal Neuralgia | Phase 2 | 1997-12-01 |
| Completed | Local Flurbiprofen to Treat Pain Following Wisdom Tooth Extraction Pain | Phase 2 | 1997-11-01 |
| Completed | Evaluation and Treatment of Oral Soft Tissue Diseases Aphthous Stomatitis, Burning Mouth Syndrome, Lichen Planus | N/A | 1997-08-01 |
| Completed | Diagnosis and Evaluation of Patients Needing Third Molar (Wisdom Tooth) Extraction and Patients With Chronic F Facial Pain, Temporomandibular Joint Disorder | — | 1997-08-01 |
| Completed | DHEA Treatment for Sjogren's Syndrome Lacrimal Apparatus Disease, Salivary Gland Disease, Sjogren's Syndrome | Phase 2 | 1997-05-01 |
| Completed | Pilot Study of Thalidomide to Treat Sjogren's Syndrome Sjogren's Syndrome, Xerostomia | Phase 2 | 1997-05-01 |
| Completed | Pain Measurement in Healthy Volunteers Healthy, Pain | — | 1997-03-01 |
| Completed | Studies on Abnormal Bone From Patients With Polyostotic Fibrous Dysplasia and McCune Albright Syndrome Polyostotic Fibrous Dysplasia | — | 1996-12-18 |
| Completed | Thalidomide to Treat Oral Lesions in HIV-Infected Patients Acquired Immunodeficiency Syndrome, Burning Mouth Syndrome, HIV Infection | Phase 2 | 1996-06-01 |
| Completed | Structure and Functional Status of Parotid Glands Exposed to Therapeutic Irradiation Radiation Injuries, Xerostomia | — | 1996-05-01 |
| Completed | Bone Regeneration Using Bone Marrow Stromal Cells Bone Disease, Craniofacial Abnormality, Healthy | — | 1994-08-03 |
| Completed | Salivary Evaluation in Healthy Volunteers Healthy, Salivary Gland Disease | — | 1993-10-26 |
| Completed | Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss Osteoporosis | Phase 3 | 1993-08-01 |
| Completed | Dextromethorphan Versus Placebo for Neuropathic Pain Diabetic Neuropathies, Herpes Zoster, Neuralgia | Phase 2 | 1993-03-01 |
| Completed | Positron Emission Tomography to Measure Pain and Pain Control Healthy, Hyperalgesia, Pain | — | 1992-08-01 |
| Completed | Oral Manifestations of Human Immunodeficiency Virus Infection in High Risk Groups HIV Infections, Candidiasis, Oral | — | 1989-09-01 |
| Completed | Clinical Study of Oral Endosseous Titanium Implants in Edentulous Subjects Ectodermal Dysplasia, Jaw, Edentulous | — | 1986-01-01 |
| Terminated | Evaluation of Salivary Gland Dysfunction Sjogren's Syndrome, Salivary Gland | — | 1984-03-23 |
| Completed | Evaluation of Patients With Unusual Diagnostic or Treatment Considerations Healthy, Tooth Disease | N/A | 1982-04-01 |