NCT00004781

Oral Manifestations of Human Immunodeficiency Virus Infection in High Risk Groups

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 250 (planned)
• Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) · NIH
• Sex: All
• Age: 0 Years
• Healthy volunteers: Accepted

Summary

OBJECTIVES: I. Evaluate the development of oral manifestations of human immunodeficiency virus infection in relationship to the onset of immunologic alterations and systemic symptoms in different risk groups: gay/bisexual men, male intravenous drug users, and female intravenous drug users. II. Evaluate the immune and inflammatory response to periodontal and other microbial pathogens. III. Evaluate the bacterial species infecting the oral cavity in patients in these risk groups.

Detailed description

PROTOCOL OUTLINE: Patients undergo a periodontal assessment every 6 months until medically unable to continue. The oral/dental exam includes saliva and gingival crevicular fluid analysis and, as indicated, oral photographs.

Conditions

• HIV Infections
• Candidiasis, Oral

Timeline

• Start date: 1989-09-01
• First posted: 2000-02-25
• Last updated: 2005-06-24