| Not Yet Recruiting | Trial of Tirzepatide for the Treatment of Cannabis Use Disorder Cannabis Use Disorder | Phase 2 | 2026-11-15 |
| Not Yet Recruiting | VK4-116 Phase I Study With Food-Effect Opioid Dependence, Opioid Use Disorder (OUD) | Phase 1 | 2026-08-01 |
| Suspended | Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and W Opioid Use Disorder, Healthy Volunteers | N/A | 2026-04-22 |
| Recruiting | SMART-r: Substance Monitoring and Active Relapse Tracking Repository Alcoholism, Substance-Related Disorders | — | 2026-04-22 |
| Enrolling By Invitation | Development of an Interview-Informed Timeline Follow-Back (TLFB) for Opioid Use in the Era of Fentanyl Substance Use Disorders (SUDs) | — | 2026-04-22 |
| Recruiting | Environment and Alcohol: A Pilot Study Alcohol Use Disorder | Phase 1 | 2026-04-22 |
| Not Yet Recruiting | Phase I Trial of High-Density Theta Burst Stimulation (hdTBS) Healthy Volunteers | Phase 1 | 2026-04-22 |
| Not Yet Recruiting | Causal Mechanisms of Odor-Guided Behavior in Humans Normal Physiology | EARLY_Phase 1 | 2026-04-22 |
| Recruiting | Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making Normal Physiology | EARLY_Phase 1 | 2026-04-22 |
| Not Yet Recruiting | Phase 1 Study of Oral MG001 Safety and Tolerability in Healthy Subjects | Phase 1 | 2026-02-01 |
| Terminated | Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pil Vaping Teens, Healthy Volunteers | N/A | 2025-05-07 |
| Completed | SXC-2023 Cocaine Interaction Study Cocaine Use Disorder | Phase 1 | 2024-10-11 |
| Recruiting | Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP Substance Use Disorder, Alcohol Use Disorder | — | 2024-09-04 |
| Recruiting | Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder Methamphetamine-dependence, Methamphetamine Abuse | Phase 3 | 2024-07-01 |
| Recruiting | Semaglutide Therapy for Alcohol Reduction (STAR) Addiction, Alcohol Use Disorder | Phase 2 | 2023-10-17 |
| Recruiting | Spironolactone in Alcohol Use Disorder (SAUD) Alcohol Use Disorder | Phase 1 | 2023-07-13 |
| Recruiting | Development and Validation of Learning and Decision-Making Tasks Normal Physiology | — | 2023-03-29 |
| Terminated | Adolescent Vaping Characterization and Parent Views on Adolescent Vaping Protocol Healthy Volunteers, Vaping Teens | — | 2023-03-09 |
| Recruiting | Orexin s Role in the Neurobiology of Substance Use Disorder Nicotine Dependence | N/A | 2023-02-15 |
| Recruiting | Defining Neurobiological Links Between Substance Use and Mental Illness Major Depressive Disorder, Substance Use Disorder, Normal Physiology | N/A | 2023-02-02 |
| Completed | Real-world Momentary Assessment of Kratom Use Accompanied by Product Assays: A Natural-history Study for Inter Chronic Pain, Fatigue, Substance Use Disorders | — | 2022-07-20 |
| Completed | Biased Opioid Agonists for Treatment of Opioid Withdrawal in OUD Opioid-Use Disorder | Phase 2 | 2021-12-27 |
| Unknown | Evaluation of the Interactions of Cannabidiol (CBD) With Morphine Opioid Use Disorder | Phase 1 | 2021-11-04 |
| Completed | Manipulating Ghrelin Signaling Via GOAT Inhibition in Alcohol Use Disorder Alcohol Use Disorder | Phase 1 / Phase 2 | 2021-06-22 |
| Terminated | Just-In-Time Adaptive Interventions for Addictive Behaviors Addiction | N/A | 2020-02-19 |
| Terminated | Imaging Biomarker for Addiction Treatment Outcome Opioid-Related Disorders, Alcohol-Related Disorders | — | 2019-07-10 |
| Recruiting | Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder Opioid-Related Disorders, Drug Addiction | — | 2019-06-07 |
| Withdrawn | State and Trait Mediated Response to TMS in Substance Use Disorder Nicotine Dependence | N/A | 2018-09-27 |
| Recruiting | Mechanism of Non-invasive Magnetic Stimulation Healthy Volunteers | N/A | 2018-09-19 |
| Completed | Comparison of Naloxone Pharmacokinetics Opioid-use Disorder | Phase 1 | 2018-01-03 |
| Completed | Lorcaserin in the Treatment of Cocaine Use Disorder Cocaine-Related Disorders | Phase 2 | 2017-12-19 |
| Completed | Evaluation of the Effects of Cannabidiol (CBD) Compared to Delta-9-Tetrahydrocannabinol (THC) and Alprazolam Cannabis Use Disorder | Phase 1 | 2017-12-04 |
| Completed | Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder Via Microbiota Investigations: A Pilot Alcoholism | — | 2017-08-28 |
| Completed | Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers Opioid-Related Disorders | Phase 1 | 2017-06-01 |
| Completed | Effects of a New Behavioral Intervention on Alcohol Craving and Drinking Alcohol Drinking, Alcohol Drinking Related Problems | N/A | 2017-05-05 |
| Terminated | Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use Cocaine Use Disorder, Cocaine Dependence | N/A | 2017-02-13 |
| Completed | Pharmacokinetic Evaluation of Intranasal, Intramuscular, and Oral Naltrexone in Healthy Volunteers Opioid-Related Disorders | Phase 1 | 2016-07-01 |
| Completed | Evaluation of Intranasal Naltrexone and Naloxone Opioid-use Disorder | Phase 1 | 2015-10-05 |
| Completed | The Study of AZD8529 for Smoking Cessation in Female Smokers Tobacco Use Disorder | Phase 2 | 2015-07-01 |
| Completed | Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin Cocaine Abuse | Phase 1 | 2015-05-01 |
| Completed | Pharmacokinetic Evaluation of Intranasal and Intramuscular Naloxone in Healthy Volunteers Drug Overdose, Opioid-Related Disorders | Phase 1 | 2014-10-01 |
| Completed | Repetitive Transcranial Magnetic Stimulation Equipment Testing and Pilot Study Healthy Volunteer | N/A | 2014-09-03 |
| Completed | Impact of Delta Opioid Receptor Gene (OPRD1) Variations on Treatment Outcome in African Americans Genetic Underpinning of Substance Abuse, Polymorphism-genetic, Drug Abuse/Dependence | — | 2014-08-23 |
| Completed | Effects of Cannabis Administration Routes on Human Performance and Pharmacokinetics Cannabis Use | Phase 1 | 2014-06-14 |
| Completed | Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity Nicotine Dependence | — | 2013-11-06 |
| Completed | Brain Networks and Addiction Susceptibility Nicotine Dependence | Phase 1 | 2013-08-14 |
| Completed | Nicotine Withdrawal Symptoms and Smoking Relapse Nicotine Dependence | N/A | 2013-05-20 |
| Completed | Laboratory Study of Cannabidiol on the Effects of Smoked Marijuana Smoking, Marijuana | Phase 2 | 2013-05-01 |
| Withdrawn | Tobacco Cessation: Treatment Delivery and Predictors of Outcome Nicotine Dependence | — | 2013-04-27 |
| Completed | A Multi-Center Trial of Nepicastat for Cocaine Dependence Cocaine Dependence | Phase 2 | 2013-04-01 |
| Completed | Three Strategies for Implementing Motivational Interviewing on Medical Inpatient Units See One, Do One, Order One | N/A | 2013-02-21 |
| Completed | Interactions Between Intravenous Cocaine and Acetazolamide or Quinine Cocaine Use, Pharmacokinetics | Phase 1 | 2012-10-24 |
| Completed | Studying Nicotine Addiction With Transcranial Magnetic Stimulation Nicotine Dependence | — | 2012-09-10 |
| Completed | Understanding Drug Abuse Treatment Outcomes Drug Abuse/Dependence | — | 2012-07-19 |
| Completed | Factors Affecting Methamphetamine and Opiates Drug Testing Opiates, Healthy | Phase 1 | 2012-07-19 |
| Completed | Health Outcomes by Neighborhood - Baltimore Stigma, Activity Space, Social Networks | — | 2012-07-17 |
| Completed | Individual Differences in Reward and Impulse Control Drug Addiction, Vulnerability to Substance Addiction | — | 2012-06-08 |
| Terminated | Pexacerfont for Stress-induced Food Craving Daily Oral Pexacerfont for 28 Days (300 mg/Day Loading Dose for 7 Days, Followed, Placebo | EARLY_Phase 1 | 2012-06-01 |
| Withdrawn | Pexacerfont to Reduce Stress-induced Tobacco Craving Nicotine Dependence | — | 2012-02-24 |
| Completed | Stem Cell Study of Genetics and Drug Addiction Induced Pluripotent Stem Cells | — | 2012-02-07 |
| Terminated | Pioglitazone to Treat Opioid Withdrawal Symptoms Opioid-Related Disorders | Phase 1 | 2012-01-04 |
| Withdrawn | Teenagers, Drug Addiction, and Reward and Impulse Control Adolescents, Conduct Disorder, Vulnerability to Substance Addicition | — | 2011-09-11 |
| Completed | Phase 1 Naltrexone-Bupropion-Methamphetamine Interaction Study Methamphetamine Dependence | Phase 1 | 2011-08-01 |
| Completed | Brain Functions Underlying Visuospatial Attention Deficits in Schizophrenia Schizophrenia | — | 2011-07-03 |
| Completed | Brain Circuits in Schizophrenia and Smoking Schizophrenia, Smoking Cessation, Nicotine Abuse | — | 2011-05-16 |
| Completed | Neutral Correlates of Risk-taking in Adolescents Exposed to Drugs Prenatally Exposure | — | 2011-05-15 |
| Withdrawn | Effect of Varenicline on Tobacco Addiction and on Abstinence-induced Cognitive Impairment Drug Addiction | Phase 1 | 2011-02-13 |
| Completed | Characterization of Phenotypic and Genotypic Regressors for Imaging Healthy Volunteers, Substance Use Disorders | — | 2010-11-18 |
| Withdrawn | Nicotinic Receptor Density in Smoking and Nonsmoking Schizophrenics Schizophrenia | — | 2010-10-31 |
| Completed | Nicotinic Modulation of the Default Network of Resting Brain Function Nicotine Dependence | — | 2010-10-24 |
| Withdrawn | Pilot Study of Repetitive Transcranial Magnetic Stimulation in Cocaine Craving Cocaine Use | Phase 1 | 2010-10-11 |
| Completed | Automated Prize-based Contingency Management to Increase Counseling Attendance in Opiate-Replacement-Therapy P Opiate-Replacement Therapy | EARLY_Phase 1 | 2010-10-03 |
| Completed | Assessment of Cannabis Craving in Schizophrenia Using Virtual Reality Cannabis Use | — | 2010-09-26 |
| Completed | Effects of Antipsychotics on Eating and Food Craving in People With Schizophrenia Schizophrenia, Obesity | — | 2010-09-26 |
| Terminated | Interactions Between Intravenous (IV) Cocaine and Lofexidine Cocaine Related Disorders | Phase 1 | 2010-08-01 |
| Completed | The Effects of Expectation on Natural and Drug -Induced Rewards Drug Abuse | — | 2010-05-24 |
| Completed | Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic Polymorphisms Nicotine Dependence | — | 2010-03-16 |
| Completed | Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis Cannabis Use, Drug Abuse | Phase 1 | 2010-01-22 |
| Completed | Assessing Top Down and Bottom Up Attention Mechanisms in Smokers Using Nicotine Nasal Spray Drug Addiction, Nicotine Dependence | Phase 1 | 2010-01-21 |
| Completed | Phase 1 Study to Evaluate RDC-0313 Coadministered With Buprenorphine to Opioid-Experienced Healthy Adults Substance-Related Disorders | Phase 1 | 2010-01-01 |
| Completed | Measuring Distress Tolerance With Functional MRI Cocaine Dependence | — | 2009-12-04 |
| Completed | Human Factors Analysis in VR for Burn Treatment Pain, Chronic Pain | Phase 1 / Phase 2 | 2009-11-01 |
| Completed | Prenatal Drug Exposure: Effects on the Adolescent Brain and Behavior Development Drug Abuse, Prenatal Drug Exposure | — | 2009-10-16 |
| Withdrawn | Pilot Study Repetitive Transcranial Magnetic Stimulation (rTMS) in Cannabis Craving Cannabis Use | Phase 1 | 2009-08-19 |
| Completed | Risk Perception in Drug-Dependent Adults With and Without Schizophrenia Cocaine Dependence, Cannabis Dependence, Schizophrenia | — | 2009-08-18 |
| Completed | Assessment of Craving in Nicotine-Dependent Patients With Schizophrenia Using Virtual Reality Nicotine Dependence | — | 2009-07-28 |
| Completed | Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatie Stress, Drug Abuse | — | 2009-07-14 |
| Terminated | Brain Glutamate Receptors and Cocaine Dependence Drug Abuse, Cocaine Dependence | — | 2009-07-14 |
| Completed | Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction Nicotine Dependence | Phase 1 | 2009-07-13 |
| Completed | Reinforcement-Based Treatment for Pregnant Drug Abusers Drug Use Disorders During Pregnancy | Phase 2 / Phase 3 | 2009-07-01 |
| Completed | Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From Nonsmokers Nicotine Dependence | — | 2009-06-08 |
| Completed | Effects of Nicotine on Areas of Impaired and Preserved Functioning in Schizophrenia Nicotine Dependence, Schizophrenia | — | 2009-06-02 |
| Completed | Screening Protocol for the Evaluation of Research Participants at the Maryland Psychiatric Research Center (MP Substance Use Disorders | — | 2009-05-28 |
| Unknown | Sublingual Buprenorphine for Chronic Pain Chronic Pain | Phase 2 | 2009-04-01 |
| Completed | Effectiveness of Motivational Interviewing Supervision in Community Programs Signs and Symptoms, Clinical Supervision | Phase 2 / Phase 3 | 2009-01-01 |
| Completed | A Multi-Modal Investigation of the Smoking Cessation Medication Varenicline: Dopaminergic Modulation of Reward Tobacco Use Disorder, Nicotine Dependence | — | 2008-11-25 |
| Terminated | Oxytocin and Cognitive Behavioral Therapy in Drug Dependence Drug Dependence | Phase 4 | 2008-11-01 |
| Completed | Individual and Group Intervention Formats With Aggressive Children Aggressive Behavior | N/A | 2008-09-01 |
| Completed | Buprenorphine Naltrexone-P1 A-Cocaine Cocaine-related Disorders | Phase 1 | 2008-08-01 |
| Completed | Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Adolescent Nicotine Dependence | — | 2008-06-10 |
| Completed | Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients Cocaine Dependence, Cocaine-Related Disorders, Opioid-Related Disorders | Phase 1 | 2008-05-08 |
| Completed | Phase 2, Double-Blind, Placebo-Controlled Trial of Bupropion for Methamphetamine Dependence Methamphetamine Dependence | Phase 2 | 2008-05-01 |
| Completed | Vigabatrin Ph 1 Cocaine Interaction Study Cocaine Addiction | Phase 1 | 2008-02-01 |
| Completed | Effects of Smoking on Opioid Receptor Binding: A PET Study Substance-related Discorder | Phase 1 | 2008-01-17 |
| Withdrawn | Psychology of Reward and Punishment: Functional and Molecular Brain Imaging and Monoaminergic Correlates Cocaine Addiction, Cocaine Abuse | — | 2007-12-12 |
| Terminated | Effects of Propranolol on Responses to Drug-Related Imagery Scripts Cocaine Dependence | Phase 1 | 2007-12-12 |
| Completed | Phase 2, Multi-Center Trial of Modafinil for Methamphetamine Dependence Methamphetamine Dependence | Phase 2 | 2007-12-01 |
| Completed | The Discriminative Effects of Tramadol in Humans Opioid Abuse, Opioid Addiction, Stimulant Abuse | Phase 1 / Phase 2 | 2007-11-01 |
| Completed | Preventing Substance Use and Risky Behavior Among Rural African American Youth Risky Sexual Behavior | N/A | 2007-11-01 |
| Completed | PET Imaging of Nicotinic Acetylcholine Receptors Healthy Volunteers, Nicotine Dependence, Pharmacokinetics | — | 2007-08-31 |
| Completed | Optimizing Toxicological Screening in Drug Endangered Children Substance Abuse Detection | — | 2007-07-10 |
| Completed | Selegiline for Smoking Cessation - 1 Nicotine Dependence | Phase 2 | 2007-06-01 |
| Completed | Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, Cannabis, Dependence, Cannabis Abuse | Phase 1 | 2007-05-08 |
| Terminated | Ph1 Marinol Interaction Study - Part 1 - 1 Marijuana Dependence | Phase 1 | 2007-03-01 |
| Completed | A Timeline Study of Alcohol Use and Its Relationship to Insomnia Insomnia, Alcohol Problem | — | 2007-03-01 |
| Completed | The Neural Basis of Cue-Elicited Cigarette Craving and Its Control Nicotine Dependence | N/A | 2007-01-09 |
| Completed | Ph1 Marinol Interaction Study - Part 2 - 1 Marijuana Dependence | Phase 1 | 2006-10-01 |
| Completed | Multi-Level HIV Prevention for Pregnant Drug Abusers Substance Related Disorders | N/A | 2006-10-01 |
| Completed | Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia Hyperalgesia, Opioid-Related Disorders | N/A | 2006-10-01 |
| Completed | Evaluating Alternative Aftercare Models for Ex-offenders Drug/Substance Abuse/Addiction, Alcohol Abuse/Addiction | Phase 2 | 2006-09-01 |
| Completed | The Neuropsychiatric Evaluation of HIV-Positive and Negative Drug Using Individuals: Study 215 HIV Infections | — | 2006-09-01 |
| Completed | Screening Protocol for the Evaluation of Potential Research Subjects Addiction | — | 2006-08-23 |
| Completed | Screening Protocol for the Evaluation of Research Participants Substance Abuse, Disorders | — | 2006-05-17 |
| Completed | Influence of Nicotine on Cognitive Function in Schizophrenic Patients With and Without Comorbid Drug Dependenc Schizophrenia, Drug Abuse/Dependency | — | 2006-05-14 |
| Completed | Rivastigmine For Methamphetamine Dependent Individuals Substance-Related Disorders | Phase 1 | 2006-05-01 |
| Completed | Efficacy of NicVAX in Smokers Who Want to Quit Smoking Smoking Cessation | Phase 2 | 2006-05-01 |
| Completed | Antagonist-Elicited Cannabis Withdrawal Cannabis, Dependence | Phase 1 | 2006-04-16 |
| Completed | Study of Smoking Abstinence Substance Abuse Disorders | — | 2006-04-07 |
| Completed | Topiramate for the Treatment of Methamphetamine Dependence - 1 Methamphetamine | Phase 2 | 2006-04-01 |
| Completed | Neuroimaging Studies of Neurophysiological Phenotypes in Schizophrenia Schizophrenia, Psychosis | — | 2006-02-14 |
| Completed | Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers Substance Related Disorder, Nicotine Dependence | Phase 1 | 2006-02-14 |
| Unknown | Tolerability and Safety of 30, 45, and 60 mg of Sublingual Lobeline. - 1 Methamphetamine Dependence | Phase 1 | 2006-02-01 |
| Completed | Strategies to Help Adult ED Patients Quit Smoking Tobacco Use | N/A | 2006-01-01 |
| Completed | Emergency Department Initiated Tobacco Treatment (EDITT) Tobacco Use | Phase 1 / Phase 2 | 2005-12-01 |
| Completed | Quiting Marijuana Use: Self-report Study of Quitting Straegies and Withdrawal Symptoms Cannabis Abuse, Cannabis Dependence | — | 2005-11-08 |
| Completed | Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients Opioid-Related Disorders | Phase 1 | 2005-11-08 |
| Completed | Effectiveness of Bupropion Combined With Behavioral Therapy for Treating Methamphetamine Dependence - 2 Methamphetamine | Phase 2 | 2005-10-01 |
| Completed | Smoking and Alcohol Initiation Smoking, Alcohol Drinking | — | 2005-10-01 |
| Completed | Effect of Functional Genetic Polymorphisms on Brain Morphology and Function Drug Abuse | — | 2005-09-13 |
| Completed | A Survey on Consumer Use of Over-the-Counter (OTC) Nicotine Patches Nicotine Dependence, Tobacco Use Disorder | — | 2005-09-01 |
| Completed | Assessing the Variability Over Time of Tobacco Carcinogen Biomarkers in Smokers - 2 Tobacco Use Disorder | — | 2005-09-01 |
| Completed | Effectiveness of Reducing Smoking in Facilitating Smoking Cessation in Adolescents - 2 Smoking Cessation, Tobacco Use Disorder | Phase 2 / Phase 3 | 2005-09-01 |
| Completed | Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1 Cocaine-Related Disorders | Phase 1 | 2005-08-01 |
| Completed | Impact of Smoking Cessation on Sleep - 5 Tobacco Use Cessation, Sleep Disorders | Phase 4 | 2005-08-01 |
| Completed | Effect of Clonidine on Responses to Imagery Scripts Cocaine Abuse, Heroin Abuse | Phase 1 | 2005-06-14 |
| Completed | Metabolic Effects of Cocaine Cocaine Dependence | N/A | 2005-06-01 |
| Completed | Smoking Treatment of Prisoners Tobacco Use Cessation, Tobacco Use Disorder | Phase 3 | 2005-06-01 |
| Completed | Cognitive Task Development and Implementation for Functional MRI Studies Drug Abuse, Nicotine Dependence | — | 2005-05-22 |
| Completed | Effectiveness of Bupropion for Smokers Recovering From Alcohol Dependence Smoking Cessation, Alcohol-Related Disorders | Phase 3 | 2005-04-01 |
| Completed | Drug Use Prevention Among Girls Through a Mother-Daughter Intervention Adolescent Behavior | Phase 3 | 2005-04-01 |
| Completed | Addition of Naltrexone to Methadone Taper Heroin Dependence, Opioid-Related Disorders, Substance-Related Disorders | Phase 2 | 2005-04-01 |
| Completed | Reward Processing in Cocaine Addiction Drug Abuse, Cocaine Dependence | — | 2005-03-17 |
| Completed | Dopamine Function and Reward Processing In Schizophrenia Schizophrenia | — | 2005-03-08 |
| Completed | Effectiveness of Selegiline in Treating Marijuana Dependent Individuals - 1 Marijuana Abuse | Phase 2 | 2005-03-01 |
| Completed | Effectiveness of Bupropion in Treating Marijuana Dependent Individuals Marijuana Abuse, Substance-Related Disorders | Phase 2 | 2005-03-01 |
| Unknown | Assessment of Interactions Between Intravenous Methamphetamine and Modafinil - 1 Amphetamine-Related Disorders | Phase 1 | 2005-03-01 |
| Completed | Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine Tobacco Dependence | Phase 2 | 2005-03-01 |
| Completed | fMRI Study of Nicotinic Effect on Neurophysiology of Schizophrenia Schizophrenia, Psychopathology, Nicotine Dependence | — | 2005-02-08 |
| Completed | Tramadol to Reduce Opioid Withdrawal Symptoms Opioid-Related Disorders | Phase 2 | 2005-02-01 |
| Unknown | Step'n Out: A Multisite Trial of Collaborative Behavioral Management for Drug-Involved Parolees Substance-Related Disorders | N/A | 2005-02-01 |
| Completed | Nicotine Lozenge to Reduce Smokeless Tobacco Use Tobacco Use Disorder | Phase 2 | 2005-01-01 |
| Terminated | Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking Tobacco Dependence | Phase 2 / Phase 3 | 2005-01-01 |
| Terminated | Methylphenidate Studies for Drug Abuse Vulnerability Molecular Genentics Substance Abuse | — | 2004-12-22 |
| Completed | Effectiveness of Tiagabine for Cocaine Dependence in Methadone-Maintained Individuals - 1 Cocaine-Related Disorders, Opiate Dependence | Phase 2 | 2004-12-01 |
| Terminated | Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals Cocaine Abuse, Cocaine-Related Disorders | Phase 1 | 2004-12-01 |
| Completed | Atomoxetine for the Treatment of Cannabis Dependence Cannabis Dependence | Phase 2 | 2004-11-01 |
| Completed | Modafinil for the Treatment of Cocaine Dependence - 1 Cocaine-Related Disorders | Phase 2 | 2004-10-01 |
| Unknown | To Assess the Safety and Tolerability of 7.5, 15 and 30 mg of Sublingual Lobeline. - 1 Amphetamine-Related Disorders | Phase 1 | 2004-09-01 |
| Unknown | Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1 Cocaine-Related Disorders | Phase 1 | 2004-09-01 |
| Completed | Low-Cost Contingency Management for Hispanic Outpatients - 3 Substance Abuse | N/A | 2004-08-01 |
| Unknown | Interactions Between Cocaine and Ethanol and Disulfiram - 1 Alcohol-Related Disorders, Cocaine-Related Disorders | Phase 1 | 2004-08-01 |
| Completed | Integration of the Therapeutic Workplace in Drug Court Drug Addiction | Phase 1 | 2004-08-01 |
| Completed | Effects of Fatty Acid Supplementation on Substance Dependent Individuals Substance-related Disorders | Phase 2 | 2004-07-01 |
| Terminated | Abuse Potential of Buprenorphine/Naloxone Opioid-Related Disorders | Phase 2 | 2004-06-01 |
| Unknown | Assessment of Interactions Between Methamphetamine and Aripiprazole - 1 Amphetamine-Related Disorders | Phase 1 | 2004-06-01 |
| Unknown | Assessment of Potential Interactions Between GBR 12909 and Cocaine - 1 Cocaine-Related Disorders | Phase 1 | 2004-06-01 |
| Completed | Baclofen for the Treatment of Cocaine Dependence - 1 Cocaine-Related Disorders | Phase 2 | 2004-06-01 |
| Completed | Effectiveness of Bupropion for Treating Nicotine Dependence in Young People Tobacco Use Cessation, Tobacco Use Disorder | Phase 2 | 2004-05-01 |
| Unknown | Implementing Tobacco Control in Dental Practice Smoking | Phase 3 | 2004-05-01 |
| Completed | Examining the Effectiveness of the Nicotine Patch in Male and Female Smokers - 2 Tobacco Use Disorder | N/A | 2004-05-01 |
| Completed | Buprenorphine as a Treatment for Individuals Dependent on Analgesic Opioids Opioid-Related Disorders | Phase 2 | 2004-05-01 |
| Completed | A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder Bipolar Disorder | Phase 1 / Phase 2 | 2004-04-01 |
| Unknown | GBR 12909 Study in Cocaine Experienced African American Volunteers - 1 Cocaine-Related Disorders | Phase 1 | 2004-04-01 |
| Completed | Neurobiology and Pharmacokinets of Acute MDMA Administration Substance-Related Disorders | Phase 1 | 2004-02-10 |
| Completed | Behavioral Smoking Cessation Treatment - 1 Tobacco Use Disorder | N/A | 2004-02-01 |
| Completed | Treatment of Heroin and Cocaine With Methadone Maintenance and Contingency Management Opiate-Related Disorders, Cocaine-Related Disorders | Phase 1 | 2004-02-01 |
| Terminated | Opioid Agonist and Antagonist Effects on Opioid Dependence Opioid-Related Disorders | Phase 2 | 2004-01-01 |
| Unknown | A Phase 1 Parallel-Group, Double-Blind, Placebo-Controlled Cardiovascular and Behavioral Study Assessing Inter Amphetamine-Related Disorders | Phase 1 | 2004-01-01 |
| Completed | Contingency Management for Attendance - 2 Substance Abuse | N/A | 2004-01-01 |
| Completed | An Hepatitis B Vaccine Model for HIV Vaccine Trials in Drug Users Hepatitis B Infection, Hepatitis C Infection, HIV Infection | Phase 3 | 2004-01-01 |
| Completed | Preventing Depression in Methadone Maintenance Patients Receiving Hepatitis C Treatment - 1 Depressive Disorder, Major, Hepatitis C | N/A | 2004-01-01 |
| Completed | Effect of Bupropion on Smoking Behavior in Smokers With Schizophrenia Schizophrenia, Tobacco Use Disorder | Phase 2 | 2004-01-01 |
| Completed | Positive Choice: Prevention for Positive Health HIV Infections, Sexual Risk Behavior, Substance Use Risks | N/A | 2003-12-01 |
| Completed | Methylphenidate Raclopride Positron Emission Tomography (PET) Test - 11 Cocaine-Related Disorders, Substance-Related Disorders | Phase 4 | 2003-12-01 |
| Recruiting | Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging Drug Abuse, Nicotine Dependence | N/A | 2003-10-24 |
| Completed | Nicotine and Cotinine Levels in Smokers With Schizophrenia and Schizoaffective Disorder - 2 Schizophrenia and Disorders With Psychotic Features, Tobacco Use Disorder | — | 2003-10-01 |
| Unknown | Interaction Between Cocaine and Quetiapine - 1 Cocaine-Related Disorders | Phase 1 | 2003-10-01 |
| Completed | A Transtheoretical Model Group Therapy for Cocaine Cocaine Use Disorders | Phase 1 | 2003-10-01 |
| Completed | Chronic Hepatitis Intervention Project for Drug Users HIV, Hepatitis C | Phase 3 | 2003-09-01 |
| Completed | Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals Heroin Dependence, Opioid-Related Disorders | — | 2003-09-01 |
| Completed | Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Stu Cocaine Addiction, Opiate Addiction | — | 2003-08-15 |
| Completed | Automatic Versus Evaluative Components of Cue Reactivity Drug Dependence | — | 2003-08-12 |
| Completed | Vouchers vs. Prizes for Methadone Patients - 1 Substance Abuse | N/A | 2003-08-01 |
| Completed | Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smok Nicotine Addiction | — | 2003-07-08 |
| Completed | Bupropion for the Treatment of Methamphetamine Dependence - 1 Amphetamine-Related Disorders | Phase 2 | 2003-07-01 |
| Completed | Modifying Group Therapy for Bipolar Substance Abusers - 1 Bipolar Disorder, Substance Dependence | N/A | 2003-07-01 |
| Completed | Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1 Cocaine-Related Disorders | Phase 1 | 2003-06-01 |
| Completed | Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1 Hepatitis C, Heroin Dependence | N/A | 2003-06-01 |
| Completed | Treatment of Acute Hepatitis C Virus Infection With Pegylated Interferon in Injection Drug Users Substance-Related Disorders, Hepatitis | Phase 4 | 2003-04-01 |
| Completed | Naltrexone as Adjunct in Alcoholic Cocaine Dependent Patients - 4 Alcohol-Related Disorders, Cocaine-Related Disorders | Phase 2 | 2003-04-01 |
| Completed | Effectiveness of N-acetylcysteine in Treating Cocaine Dependent Individuals - 1 Cocaine-Related Disorders | Phase 1 | 2003-03-01 |
| Completed | Effectiveness of Self-Help for Dually-Diagnosed Persons - 1 Dual Diagnosis, Substance-Related Disorders, Mental Disorders | Phase 1 / Phase 2 | 2003-03-01 |
| Completed | Effectiveness of Naltrexone and Lofexidine in Treating Detoxified Heroin Addicts - 1 Heroin Dependence | Phase 1 | 2003-03-01 |
| Completed | Effectiveness of Using Tobacco Free Snuff in Reducing Negative Effects of Smokeless Tobacco Use Tobacco Use Disorder | Phase 2 | 2002-12-01 |
| Completed | Comparison of Buprenorphine and Methadone - 3 Opioid-Related Disorders | Phase 2 | 2002-12-01 |
| Completed | Cocaethylene as a Treatment for Cocaine Dependence - 1 Cocaine-Related Disorders | Phase 1 | 2002-12-01 |
| Completed | Maintaining Abstinence in Chronic Cigarette Smokers - 1 Tobacco Use Disorder | Phase 2 | 2002-12-01 |
| Completed | Physician Focused Intervention to Improve Adherence With HIV Antiretrovirals HIV Infection, HIV Infections | N/A | 2002-11-01 |
| Completed | Tiagabine for the Treatment of Cocaine Dependence - 1 Cocaine-Related Disorders | Phase 2 | 2002-10-01 |
| Completed | Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI Nicotine Dependence, Drug Abuse | — | 2002-09-17 |
| Terminated | Effects of Buprenorphine/Naloxone in Treating Opioid Dependent Individuals Who Are Maintained on Methadone Opioid-Related Disorders | N/A | 2002-09-01 |
| Unknown | Hyperalgesia in Methadone Patients: Can it be Treated? Opioid-induced Hyperalgesia | Phase 1 | 2002-09-01 |
| Completed | Effects of Nicotine on Brain Activity as Measured by fMRI Nicotine Dependence, Drug Abuse | — | 2002-08-06 |
| Completed | Reinforcement-Based Treatment and Abstinence-Contingent Housing for Drug Abusers Drug Abuse | Phase 4 | 2002-08-01 |
| Unknown | Assessment of the Potential Interactions Between Cocaine and GBR 12909 - 1 Cocaine-Related Disorders | Phase 1 | 2002-08-01 |
| Completed | Clonidine as Adjunct Therapy for the Treatment of Neonatal Abstinence Syndrome Neonatal Abstinence Syndrome | Phase 2 | 2002-07-01 |
| Completed | Ondansetron for the Treatment of Methamphetamine Dependence - 1 Amphetamine-Related Disorders | Phase 2 | 2002-06-01 |
| Completed | Study to Reduce Intravenous Exposures (STRIVE) Hepatitis C, HIV Infections | Phase 2 / Phase 3 | 2002-06-01 |
| Unknown | Assessment of Potential Interactions Between Methamphetamine and Bupropion - 1 Amphetamine-Related Disorders | Phase 1 | 2002-06-01 |
| Terminated | Nicotine Replacement Treatment for Pregnant Smokers - 1 Tobacco Use Disorder | Phase 2 | 2002-06-01 |
| Completed | Combination Pharmacotherapy for Smoking Cessation Among Methadone Patients Tobacco Use Disorder | Phase 2 | 2002-06-01 |
| Completed | Effects of Transdermal Nicotine on Smoking, Craving and Withdrawal in People With Schizophrenia Schizophrenia and Disorders With Psychotic Features, Tobacco Use Disorder, Schizophrenia | Phase 2 | 2002-06-01 |
| Unknown | Development of Human Laboratory Study Model of Cocaine Relapse Prevention. - 1 Cocaine-Related Disorders | Phase 1 | 2002-05-01 |
| Completed | Effectiveness of Various Smoking Cessation Therapies in Reducing Smoking in Adolescents - 1 Smoking Cessation, Tobacco Use Disorder | Phase 2 | 2002-04-01 |
| Unknown | The Aim of This Study is to Determine the Effectiveness of a Motivational Enhancement Intervention in Reducing Adherence, HIV Risk Behaviors, Alcohol & Drug Use | Phase 2 | 2002-01-01 |
| Completed | Incentive Programs for Female Substance Abusers Who Smoke - 3 Tobacco Use Disorder | Phase 2 / Phase 3 | 2002-01-01 |
| Completed | Effects of Buspirone in Opiate Withdrawal Heroin Dependence | Phase 4 | 2002-01-01 |
| Completed | Comparing the Effects of Smoked and Oral Marijuana in Individuals With HIV/AIDS HIV Infections | Phase 1 / Phase 2 | 2001-12-01 |
| Unknown | Cocaine-Metyrapone Interaction Study - 1 Cocaine-Related Disorders, Infusions, Intravenous | Phase 1 | 2001-11-01 |
| Completed | Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens Heroin Dependence, Opioid-Related Disorders | Phase 2 | 2001-11-01 |
| Completed | Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1 Tobacco Use Cessation, Tobacco Use Disorder, Schizophrenia | Phase 2 | 2001-09-01 |
| Unknown | Psychotherapy Enhancement for Therapeutic Community (TC) Retention - 1 Substance-Related Disorders | Phase 2 | 2001-09-01 |
| Unknown | Assessment of Potential Interactions Between Methamphetamine and Selegiline - 1 Amphetamine-Related Disorders | Phase 1 | 2001-09-01 |
| Completed | Using Smokeless Tobacco Products With Lower Nicotine Levels to Reduce Negative Effects of Smokeless Tobacco Us Tobacco Use Disorder | Phase 1 / Phase 2 | 2001-08-01 |
| Completed | Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine Cocaine-Related Disorders | Phase 2 | 2001-08-01 |
| Terminated | Nicotine Patch for Nicotine Dependence in Individuals With Schizophrenia or Schizoaffective Disorder - 1 Tobacco Use Disorder | Phase 4 | 2001-08-01 |
| Completed | Reserpine for the Treatment of Cocaine Dependence - 1 Cocaine-Related Disorders, Substance-Related Disorders | Phase 2 | 2001-07-01 |
| Unknown | Assessment of Potential Interactions Between Cocaine and Tolcapone - 1 Cocaine-Related Disorders | Phase 1 | 2001-07-01 |
| Unknown | A Behavioral Trial for the Treatment of Methamphetamine Dependence. - 1 Substance-Related Disorders | Phase 2 | 2001-07-01 |
| Unknown | Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1 Cocaine-Related Disorders, Drug Administration Schedule, Infusions, Intravenous | Phase 1 | 2001-06-01 |
| Unknown | Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers - 1 Cocaine-Related Disorders, Drug Administration Schedule, Infusions, Intravenous | Phase 1 | 2001-06-01 |
| Completed | A Study of Cabergoline for the Treatment of Cocaine Dependence - 1 Cocaine-Related Disorders, Substance-Related Disorders | Phase 2 | 2001-06-01 |
| Completed | Evaluation of Benztropine for Cocaine Craving - 2 Cocaine-Related Disorders | Phase 2 | 2001-05-01 |
| Completed | Ondansetron for the Treatment of Cocaine Dependence - 1 Cocaine-Related Disorders, Drug Administration Schedule | Phase 2 | 2001-05-01 |
| Completed | Lofexidine for Opiate Withdrawal - 1 Opioid-Related Disorders | Phase 3 | 2001-04-01 |
| Completed | Serotonin, Impulsivity, and Cocaine Dependence Treatment Cocaine Dependence | Phase 2 | 2001-04-01 |
| Completed | Randomized Trial of the Positive Action Program in Hawaii Schools Character, Violence, Substance Use | N/A | 2001-04-01 |
| Completed | Integrated Treatment for Cocaine and Mood Disorders - 1 Cocaine Dependence, Depressive Disorder, Major | Phase 2 | 2001-04-01 |
| Completed | Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts Cocaine-Related Disorders, Opioid-Related Disorders | N/A | 2001-04-01 |
| Completed | Selegiline Transdermal System for the Treatment of Cocaine Dependence - 1 Cocaine-Related Disorders | Phase 3 | 2001-03-01 |
| Completed | Substance Dependent Teens - Impact of Treating Depression Study 1 - 1 Alcohol-Related Disorders, Marijuana Abuse, Substance-Related Disorders | Phase 4 | 2001-02-01 |
| Completed | Reduction of Smoking in Cardiac Disease Patients Cardiovascular Disease, Tobacco Use Disorder | Phase 2 | 2001-01-01 |
| Completed | Physiological, Cognitive and Cerebral Activity Changes as a Function of Cigarette Smoking (With or Without Nic Smoking Cessation | — | 2000-12-05 |
| Completed | Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence Opioid-Related Disorders | N/A | 2000-12-01 |
| Completed | Naltrexone Augmentation of Nicotine Patch Therapy - 1 Tobacco Use Disorder | Phase 3 | 2000-11-01 |
| Completed | Methadone Levels in Breast Milk of Women Taking Methadone for Opiate Addiction - 2 Breast Feeding, Opioid-Related Disorders | — | 2000-11-01 |
| Completed | Examining the Role of Negative Emotional States on Sedative Drug Use in Individuals With Post-Traumatic Stress Stress Disorders, Post-Traumatic | — | 2000-10-01 |
| Completed | Medication Adherence Therapy for Opioid Abusing Pain Patients Pain, Chronic Disease, Prescription Opioid Abuse | Phase 1 / Phase 2 | 2000-09-01 |
| Completed | Effectiveness of Nefazodone and Bupropion in Treating Marijuana Dependent Individuals Marijuana Abuse | Phase 2 | 2000-09-01 |
| Completed | Effectiveness of Divalproex Sodium (Depakote) in Treating Children With Temper Outbursts and Severe Mood Swing Mood Disorders | Phase 2 | 2000-09-01 |
| Completed | Maintenance Treatment for Abstinent Smokers Tobacco Use Disorder | Phase 3 | 2000-08-01 |
| Completed | Chemical Dependency and Smoking Cessation: Patient's Views - 1 Tobacco Use Disorder | — | 1999-12-01 |
| Completed | Cognitive Behavioral Stress Management for HIV+ Drug Abusers HIV/AIDS, Drug Abuse, Alcohol Abuse | Phase 1 | 1999-09-01 |
| Completed | Student Athlete Testing Using Random Notification Drug Abuse, Alcohol Abuse, Substance Abuse | N/A | 1999-09-01 |
| Completed | Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Depend Tobacco Dependence | Phase 2 / Phase 3 | 1999-08-01 |
| Completed | Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14 Opioid Dependence, Substance-Related Disorders | Phase 4 | 1999-08-01 |
| Completed | Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse Opioid Dependence, Cocaine Abuse | Phase 1 | 1999-06-01 |
| Completed | Progesterone Treatment in Female Smokers - 12 Tobacco Use Disorder | Phase 2 | 1999-04-01 |
| Completed | Bupropion as an Adjunct to the Nicotine Patch Plus CBT Tobacco Use Disorder | Phase 4 | 1999-04-01 |
| Completed | Tiagabine, Sertraline, or Donepezil for the Treatment of Cocaine Dependence - 9 Cocaine-Related Disorders | Phase 2 | 1999-03-01 |
| Unknown | Effects of Stimulant Dependence on Human Striatal Dopamine System - 15 Amphetamine-Related Disorders, Tobacco Use Disorder | Phase 1 | 1999-03-01 |
| Completed | Effect of Nefazodone on Relapse in Females With Cocaine Abuse - 10 Cocaine-Related Disorders | Phase 3 | 1999-01-01 |
| Completed | Motivation and Patch Treatment for HIV-positive Smokers HIV Infections, Smoking Cessation | Phase 3 | 1999-01-01 |
| Completed | Effects of Labetalol on Nicotine Administration in Humans - 14 Tobacco Use Disorder | Phase 2 | 1998-10-01 |
| Completed | Effects of Carvedilol on Cocaine Use in Humans - 11 Cocaine-Related Disorders | Phase 2 | 1998-09-01 |
| Completed | Methylphendidate Treatment of Cocaine Dependent Patients With Attention Deficit Hyperactivity Disorder - 3 Cocaine-Related Disorders | Phase 2 | 1998-09-01 |
| Completed | Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke Tobacco-Use Disorder, Schizophrenia, Psychotic Disorders | Phase 4 | 1998-08-01 |
| Completed | PET Assays of Striatal Dopamine Marker in Cocaine Craving Neural Systems, Drug Abuse, Cocaine Dependence | — | 1998-06-23 |
| Completed | High Dose Nimodipine Treatment Adjunct - 1 Cocaine-Related Disorders | Phase 2 | 1998-05-01 |
| Completed | Role of Metabolites in Nicotine Dependence (3) - 6 Tobacco Use Disorder | Phase 2 | 1998-05-01 |
| Completed | Cocaine-Methylphendidate Interaction Study - 4 Cocaine-Related Disorders | Phase 1 | 1997-12-01 |
| Completed | Role of Metabolites in Nicotine Dependence (4) - 13 Tobacco Use Disorder | Phase 2 | 1997-11-01 |
| Completed | Resperine, Gabapentin, or Lamotrigine for the Treatment of Cocaine Dependence: 2 - 7 Cocaine-Related Disorders | Phase 2 | 1997-11-01 |
| Completed | Buprenorphine Formulation Comparison: Sublingual Tablet vs. Solution - 1 Opioid-Related Disorders | Phase 1 / Phase 2 | 1997-10-01 |
| Completed | Effects of Labetalol on Human Cocaine Use - 8 Cocaine-Related Disorders | Phase 2 | 1997-10-01 |
| Completed | Temporal Discounting Delayed Outcomes on Opioid-Dependent Outpatients - 20 Opioid-Related Disorders | Phase 2 | 1997-08-01 |
| Completed | Dextroamphetamine as an Adjunct in Cocaine Treatment - 1 Cocaine-Related Disorders, Substance-Related Disorders | Phase 2 | 1997-08-01 |
| Completed | Risperidone for Treatment of Cocaine Dependence in Outpatients - 12 Cocaine-Related Disorders | Phase 2 | 1997-07-01 |
| Completed | Methylphenidate in the Treatment of Cocaine Dependent Patients With Adult Attention Deficit Hyperactivity Diso Cocaine-Related Disorders, Substance-Related Disorders | Phase 2 | 1997-06-01 |
| Completed | Stress Hormones and Human Cocaine Use - 7 Cocaine-Related Disorders | Phase 1 | 1997-05-01 |
| Completed | Buprenorphine Detoxification - BBDVI - 19 Opioid-Related Disorders | Phase 2 | 1997-05-01 |
| Completed | Tyrosine for Methamphetamine Dependence - 1 Amphetamine-Related Disorders | Phase 2 | 1997-04-01 |
| Completed | Modeling Impaired Judgement in Cocaine Abusers - 6 Cocaine-Related Disorders, Substance-Related Disorders | Phase 4 | 1997-03-01 |
| Completed | Phase II Double-Blind, Placebo-Controlled Study of the Reinforcing Effects of Alprazolam in Patients With Anxi Anxiety Disorder, Panic Disorder | Phase 2 | 1997-03-01 |
| Completed | The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Coc Behavior Therapy, Cocaine, Contingency Management | Phase 2 | 1997-03-01 |
| Completed | Flupenthixol and Haloperidol for Treating Cocaine Abuse Schizophrenics - 9 Cocaine-Related Disorders, Substance-Related Disorders | Phase 2 | 1997-03-01 |
| Completed | Tryptophan and Behavior Therapy for Cocaine Abuse - 1 Cocaine-Related Disorders | Phase 2 | 1997-03-01 |
| Completed | Prepulse Inhibition of Startle in Cocaine Dependence - 7 Cocaine-Related Disorders, Substance-Related Disorders | Phase 1 | 1997-02-01 |
| Completed | Cocaine Effects in Humans: Physiology and Behavior - 1 Cocaine-Related Disorders | Phase 2 | 1997-01-01 |
| Completed | Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users Opioid-Related Disorders | N/A | 1997-01-01 |
| Completed | Effects of Nefazodone on Treatment of Female Cocaine Abusers - 3 Cocaine-Related Disorders | Phase 2 | 1996-12-01 |
| Completed | Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1 Opioid-Related Disorders, Substance-Related Disorders | Phase 2 | 1996-12-01 |
| Completed | Cocaine Abuse and ADHD - 10 Cocaine-Related Disorders | Phase 2 | 1996-11-01 |
| Completed | Buprenorphine Dose Escalation Trial for Treatment of Non-Dependent Opiate Users - 2 Opioid-Related Disorders, Substance-Related Disorders | Phase 1 | 1996-11-01 |
| Completed | Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1 Cocaine-Related Disorders | Phase 1 | 1996-11-01 |
| Completed | Buprenorphine and Naloxone Combination Study - 10 Heroin Dependence, Opioid-Related Disorders | Phase 1 | 1996-11-01 |
| Completed | Buprenorphine/Naloxone for Opiate-Dependence Treatment - 1 Opioid-Related Disorders, Substance-Related Disorders | Phase 2 | 1996-11-01 |
| Completed | Trial of Buprenorphine/Naloxone for Opiate Dependence - 2 Opioid-Related Disorders, Substance-Related Disorders | Phase 2 | 1996-10-01 |
| Completed | Methamphetamine Abuse Treatment in Patients With AIDS - 1 Substance-Related Disorders | Phase 4 | 1996-10-01 |
| Completed | Evaluation of Liquid vs. Tablet Buprenorphine - 6 Opioid-Related Disorders | Phase 2 | 1996-08-01 |
| Completed | Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2 Cocaine-Related Disorders | Phase 1 | 1996-08-01 |
| Completed | Effects of Buprenorphine/Naloxone Administered in Different Ways For Treating Opioid Dependence Opioid-Related Disorders | N/A | 1996-08-01 |
| Completed | Risperidone for the Treatment of Cocaine Dependence - 7 Cocaine-Related Disorders | Phase 2 | 1996-07-01 |
| Completed | Therapeutic Potential of Kappa-Opioids Against Cocaine - 1 Cocaine-Related Disorders | — | 1996-07-01 |
| Completed | Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 3 Opioid-Related Disorders, Substance-Related Disorders | Phase 1 | 1996-07-01 |
| Unknown | Infusion Laboratory: Protocol 3 (Risperidone) - 4 Cocaine-Related Disorders | Phase 1 | 1996-06-01 |
| Withdrawn | Pemoline in the Treatment of Stimulant Dependence - 5 Cocaine-Related Disorders | Phase 2 | 1996-06-01 |
| Completed | Effects of Phenytoin on Cocaine Use in Humans - 2 Cocaine-Related Disorders | Phase 1 | 1996-05-01 |
| Completed | Evaluation of Lofexidine for Treatment of Opiate Withdrawal - 10 Opioid-Related Disorders | Phase 1 | 1996-04-01 |
| Completed | Brain Changes in Stimulant Dependent Subjects - 8 Substance-Related Disorders | Phase 4 | 1996-04-01 |
| Completed | Buprenorphine and Naloxone for the Treatment of Opiate Dependence - 1 Heroin Dependence, Substance-Related Disorders | Phase 3 | 1996-04-01 |
| Completed | Acute Withdrawal From Smoked Cocaine - 9 Cocaine-Related Disorders, Substance Withdrawal Syndrome, Substance-Related Disorders | Phase 1 | 1996-04-01 |
| Unknown | Infusion Laboratory: Protocol 2 (Lisuride) - 3 Cocaine-Related Disorders | Phase 1 | 1996-03-01 |
| Terminated | Serotonin/Dopamine Antagonism of Cocaine Effect: 2 - 2 Cocaine-Related Disorders | Phase 2 | 1996-01-01 |
| Completed | Role of Metabolites in Nicotine Dependence (2) - 5 Tobacco Use Disorder | Phase 2 | 1995-12-01 |
| Completed | Pergolide Treatment for Substance Abusers - 4 Cocaine-Related Disorders, Substance-Related Disorders | Phase 2 | 1995-10-01 |
| Completed | Activity Monitoring Assessment of Opiate Withdrawal - 4 Opioid-Related Disorders | Phase 2 | 1995-09-30 |
| Completed | Dextroamphetamine-Cocaine Behavioral Intervention - 5 Cocaine-Related Disorders | Phase 2 | 1995-09-01 |
| Completed | Buprenorphine Combination Tablet Feasibility - 1 Opioid-Related Disorders | Phase 2 | 1995-08-01 |
| Completed | Cocaine Abuse and Attention Deficit Disorder - 3 Cocaine-Related Disorders | N/A | 1995-05-01 |
| Completed | Naltrexone in Treatment of Cocaine Dependence - 5 Cocaine-Related Disorders | Phase 2 | 1995-05-01 |
| Completed | Role of Metabolites in Nicotine Dependence (1) - 1 Tobacco Use Disorder | Phase 2 | 1995-02-01 |
| Completed | Relapse Patterns in Female Cocaine Users - 4 Cocaine-Related Disorders | — | 1995-02-01 |
| Unknown | Randomized Study of Interventions to Enhance Adherence to Isoniazid Prevention Therapy for Tuberculosis in Inj Tuberculosis | N/A | 1995-02-01 |
| Completed | Selegiline in Outpatient Treatment for Cocaine Dependence - 1 Cocaine-Related Disorders | Phase 2 | 1995-01-01 |
| Completed | Buprenorphine Maintenance Dose Schedule and Treatment Setting - 1 Opioid-Related Disorders, Substance-Related Disorders | Phase 2 | 1994-12-01 |
| Completed | Infusion Laboratory: Protocol 1 - Selegeline - 2 Cocaine-Related Disorders | Phase 1 | 1994-11-01 |
| Completed | Alternate-Day Buprenorphine Administration. Phase VII - 8 Opioid-Related Disorders | Phase 2 | 1994-11-01 |
| Completed | Effects of Buprenorphine and Naloxone in Opiate Addicts - 4 Opioid-Related Disorders, Substance-Related Disorders | Phase 1 | 1994-11-01 |
| Completed | M-CPP and Fenfluramine in Cocaine Addicts - 3 Cocaine-Related Disorders | Phase 2 | 1994-09-01 |
| Completed | Dextroamphetamine as Adjunct in Cocaine/Opiate Dependent Patients - 3 Cocaine-Related Disorders, Opioid-Related Disorders | Phase 2 | 1994-09-01 |
| Completed | Buprenorphine Detox With Two Types of Treatment. BBD I - 10 Opioid-Related Disorders | Phase 2 | 1994-08-01 |
| Completed | Flupenthixol Treatment in Schizophrenic Cocaine Abusers - 1 Cocaine-Related Disorders | Phase 2 | 1994-08-01 |
| Completed | Evaluation of a Desipramine Ceiling in Cocaine Abuse - 1 Cocaine-Related Disorders, Substance-Related Disorders | Phase 2 | 1994-05-01 |
| Completed | Flupenthixol Decanoate in Methamphetamine Smoking - 1 Substance-Related Disorders | Phase 2 | 1994-02-01 |
| Completed | Alternate-Day Buprenorphine Administration. Phase IV - 5 Opioid-Related Disorders | Phase 2 | 1993-06-01 |
| Completed | Alternate Day Buprenorphine Administration, Phase X - 15 Opioid-Related Disorders | Phase 2 | 1993-05-01 |
| Completed | Alternate-Day Buprenorphine. Phase V - 6 Opioid-Related Disorders | Phase 1 | 1993-02-01 |
| Completed | Alternate-Day Buprenorphine Administration. Phase VI - 7 Opioid-Related Disorders | Phase 2 | 1992-12-01 |
| Completed | Buprenorphine Dosing Interval - 5 Opioid-Related Disorders | Phase 2 | 1992-11-01 |
| Completed | The Genetic Basis for Vulnerability to Substance Abuse Substance Abuse | — | 1992-08-01 |
| Completed | Alternate-Day Buprenorphine Administration. Phase II - 4 Opioid-Related Disorders | Phase 1 | 1992-07-01 |
| Completed | Buprenorphine Maintenance for Opiate Dependence - 6 Opioid-Related Disorders, Substance-Related Disorders | Phase 2 | 1992-06-01 |
| Completed | Alternate-Day Buprenorphine Administration. Phase I - 3 Opioid-Related Disorders | Phase 1 | 1992-04-01 |
| Completed | Buprenorphine Detoxification With Two Types of Treatment. BBD IV - 13 Opioid-Related Disorders | Phase 2 | 1992-02-01 |
| Completed | Methadone/Buprenorphine Cross-Over Study - 4 Opioid-Related Disorders | Phase 2 | 1992-02-01 |
| Completed | Gradual Vs. Rapid Buprenorphine Detoxification - 2 Opioid-Related Disorders | Phase 1 | 1991-06-01 |
| Completed | Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5 Opioid-Related Disorders, Substance-Related Disorders | Phase 2 | 1991-06-01 |
| Completed | Treatment Efficacy for Drug Abuse and AIDS Prevention - 2 Cocaine-Related Disorders, Heroin Dependence | Phase 2 | 1989-09-01 |
| Completed | Treatment Efficacy for Drug Abuse and AIDS Prevention - 1 Cocaine-Related Disorders, Heroin Dependence | Phase 2 | 1989-09-01 |
| Completed | Propranolol for Treatment of Cocaine Addiction - 2 Cocaine-Related Disorders | Phase 2 | 1987-01-01 |
| Completed | Buprenorphine/Naloxone for Treatment of Opiate Dependence - 9 Opioid-Related Disorders | Phase 2 | — |
| Completed | Pathophysiological Subtyping of Abnormalities in Cocaine Dependence - 9 Cocaine-Related Disorders, Substance-Related Disorders | Phase 4 | — |
| Unknown | Cognitive Correlates of Substance Abuse, Part 2 - 16 Amphetamine-Related Disorders | — | — |
| Completed | Buprenorphine Pharmacology Related to Addiction Treatment - 18 Opioid-Related Disorders | Phase 2 | — |
| Unknown | Infusion Laboratory: Protocol 4 (Dihydrexidine) - 13 Cocaine-Related Disorders | Phase 1 | — |
| Terminated | Predictive Values of Serotonergic Alterations for Outcome - 2 Cocaine-Related Disorders | Phase 1 | — |
| Completed | Pharmacotherapy and Intensive Treatment - 2 Cocaine-Related Disorders, Substance-Related Disorders | Phase 4 | — |
| Completed | Psychostimulant Abuse - Novel Treatment Approaches - 1 Cocaine-Related Disorders | Phase 1 | — |
| Completed | Effectiveness of the Nicotine Patch in Suppressing Nicotine Withdrawal Symptoms in Women Versus Men - 1 Smoking Cessation, Tobacco Use Disorder | Phase 2 | — |
| Completed | Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 7 Opioid-Related Disorders, Substance-Related Disorders | Phase 1 | — |
| Terminated | Early Tobacco Abstinence - 5 Tobacco Use | Phase 1 | — |
| Completed | IV Cocaine Abuse: A Laboratory Model - 4 Cocaine-Related Disorders | Phase 2 | — |
| Completed | Risperidone Treatment in Dually-Diagnosed Individuals - 2 Cocaine-Related Disorders | Phase 2 | — |
| Unknown | Infusion Laboratory: Protocol 5 (Flupenthixol) - 14 Cocaine-Related Disorders | Phase 1 | — |
| Completed | Study Comparing Liquid and Tablet Buprenorphine Formulations - 5 Heroin Dependence | Phase 3 | — |
| Unknown | Cognitive Correlates of Substance Abuse - 11 Amphetamine-Related Disorders | Phase 4 | — |
| Completed | Alterations in Serotonergic Functions in Cocaine Addicts - 1 Cocaine-Related Disorders | Phase 1 | — |
| Completed | Buprenorphine Pharmacology Related to Addiction Treatment - 21 Opioid-Related Disorders | Phase 2 | — |
| Completed | Pharmacological Modulation of Cocaine Effects - 1 Cocaine-Related Disorders | Phase 2 | — |
| Unknown | Ph1 Lobeline Interaction Study - 1 Methamphetamine Dependence | Phase 1 | — |
| Completed | Alternate Day Buprenorphine Administration, Phase XII - 17 Opioid-Related Disorders | Phase 2 | — |