Trials / Completed
CompletedNCT00733720
Buprenorphine Naltrexone-P1 A-Cocaine
Attenuation of Opioid Effects of Three Different Doses of Sublingual Buprenorphine / Naloxone by Oral Naltrexone in Healthy Volunteers
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 8 (estimated)
- Sponsor
- National Institute on Drug Abuse (NIDA) · NIH
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine if the opioid agonist effects of doses of 4/1 mg, 8/2 mg, and 16/4 mg of buprenorphine/naloxone can be completely blocked by 50 mg of oral naltrexone. This study will provide data to support the design of a similar study of the depot formulation of naltrexone and ultimately to study this combination for the treatment of cocaine dependence.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Suboxone | 4/1mg, 8/2mg 16/4mg |
Timeline
- Start date
- 2008-08-01
- Primary completion
- 2008-12-01
- Completion
- 2009-01-01
- First posted
- 2008-08-13
- Last updated
- 2017-01-12
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00733720. Inclusion in this directory is not an endorsement.