NCT00033046

Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1

Safety Evaluation of Cocaine Treatment Medication Modafinil: Interactions With Intravenous Cocaine

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 12 (planned)
• Sponsor: National Institute on Drug Abuse (NIDA) · NIH
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate modafinil, a cocaine treatment medication, and its interactions with intravenous (IV) cocaine.

Detailed description

Placebo-controlled, escalating dose drug interaction study using a total of 12 cocaine users at a single site. Study duration will include four infusion sessions: 1) screening/baseline; 2) baseline; 3) 400mg/day steady-state modafinil; 4) 800 mg/day steady state modafinil. Infusion session will be 2 days in duration.

Conditions

• Cocaine-Related Disorders
• Drug Administration Schedule
• Infusions, Intravenous

Interventions

Type	Name	Description
DRUG	Modafinil

Timeline

• Start date: 2001-06-01
• Completion: 2002-04-01
• First posted: 2002-04-08
• Last updated: 2017-01-11

Locations

1 site across 1 country: United States