Clinical Trials Directory

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UnknownNCT00267657

A Phase 1 Parallel-Group, Double-Blind, Placebo-Controlled Cardiovascular and Behavioral Study Assessing Interactions Between Single Doses of Oral Reserpine and Intravenous Methamphetamine - 1

Assessment of Interactions Between IV Methamphetamine and Reserpine

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
30 (planned)
Sponsor
National Institute on Drug Abuse (NIDA) · NIH
Sex
All
Age
21 Years – 45 Years
Healthy volunteers
Not accepted

Summary

In this parallel group clinical pharmacology laboratory experiment, we will assess pharmacodynamic interactions (with a focus on cardiovascular effects) of a 15 mg intravenous methamphetamine dose and single oral doses of reserpine (0.5 and 1.0 mg) or placebo.

Detailed description

In this parallel group clinical pharmacology laboratory experiment, we will assess pharmacodynamic interactions (with a focus on cardiovascular effects) of a 15 mg intravenous methamphetamine dose and single oral doses of reserpine (0.5 and 1.0 mg) or placebo.

Conditions

Interventions

TypeNameDescription
DRUGReserpine

Timeline

Start date
2004-01-01
Completion
2004-11-01
First posted
2005-12-21
Last updated
2017-01-11

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00267657. Inclusion in this directory is not an endorsement.