NCT00490269

Ph1 Marinol Interaction Study - Part 2 - 1

Phase 1, Pilot Study to Examine the Cardiovascular Effects of Smoked Marijuana, Interactions With Oral Dronabinol, and Effects of Dronabinol on Withdrawal in Marijuana Dependent Volunteers

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: National Institute on Drug Abuse (NIDA) · NIH
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study will examine the effects of oral dronabinol tetrahydrocannabinol (THC) on withdrawal symptoms in marijuana dependent volunteers, and evaluate the safety, pharmacokinetics (PK), and cardiovascular effects of the combination of oral dronabinol and smoked marijuana to determine if there are potential significant drug interactions before conducting outpatient studies.

Conditions

• Marijuana Dependence

Interventions

Type	Name	Description
DRUG	Placebo
DRUG	Dronabinol

Timeline

• Start date: 2006-10-01
• Primary completion: 2007-12-01
• Completion: 2007-12-01
• First posted: 2007-06-22
• Last updated: 2017-01-12
• Results posted: 2013-04-08

Locations

1 site across 1 country: United States