NCT00224965

Early Tobacco Abstinence - 5

Early Tobacco Abstinence in High Risk Smokers

• Status: Terminated
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 140 (planned)
• Sponsor: National Institute on Drug Abuse (NIDA) · NIH
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This proposal will conduct a prospective examination of the clinical course (intensity, content and duration) of tobacco (nicotine) abstinence effects in male and female smokers who are either heavy/light alcohol drinkers with/without depressive symptoms.

Detailed description

1. To compare male and female smokers, with and without current depressive symptoms, in a prospective study of the intensity, content \& duration of nicotine abstinence effects during an eight-day abstinence period, and responses to cue exposure (invivo cigarette cues, alcohol and negative affect-inducing imagery cues) during acute vs. prolonged abstinence and, 2. To compare male and female smokers, who are either heavy alcohol drinkers or light alcohol drinkers, in a prospective study of the intensity, content \& duration of nicotine abstinence effects during an eight-day abstinence period, and responses to cue exposure (invivo cigarette cues, alcohol and negative affect-inducing imagery cues) during acute vs. prolonged abstinence.

Conditions

• Tobacco Use

Interventions

Type	Name	Description
BEHAVIORAL	Behavior Therapy

Timeline

• Completion: 2004-10-01
• First posted: 2005-09-23
• Last updated: 2017-01-12

Locations

1 site across 1 country: United States