Tobacco Use

271 registered clinical trials studyying Tobacco Use — 52 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	A Mindfulness-based Intervention for Sexual Assault Survivors NCT07515586	Georgia State University	N/A
Not Yet Recruiting	Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya NCT06790342	University of Chicago	Phase 3
Not Yet Recruiting	Telegram Messenger Support for Smoking Cessation After Heart Attack NCT07230249	ITMO University	N/A
Not Yet Recruiting	Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum NCT07489443	University of Pittsburgh	N/A
Enrolling By Invitation	Robot-Assisted Immersive Escape Room Game for Tobacco Harm Prevention Among Elementary School Students NCT07501572	National Taiwan Normal University	N/A
Recruiting	Little Cigar Oxidants NCT06310187	Milton S. Hershey Medical Center	N/A
Not Yet Recruiting	A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems NCT07323563	RAI Services Company	N/A
Recruiting	Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY) NCT07162935	University of Oklahoma	N/A
Not Yet Recruiting	Abuse Liability for Eight Electronic Nicotine Products NCT07323511	RAI Services Company	N/A
Recruiting	Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit NCT07199517	Abramson Cancer Center at Penn Medicine	N/A
Not Yet Recruiting	Abuse Liability for Four Heated Tobacco Product (HTP) Consumables and Two HTP Devices NCT07267195	RAI Services Company	N/A
Recruiting	Abuse Liability for Five Modern Oral Nicotine Products NCT07132814	RAI Services Company	N/A
Completed	Comparison of Demand and Substitution for Nicotine Pouches as a Function of Nicotine Dosage NCT07213947	William Middleton	N/A
Recruiting	Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness NCT07148232	University of California, San Francisco	Phase 4
Recruiting	Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Wit NCT06983678	Duke University	N/A
Recruiting	STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking NCT06922617	Medical University of South Carolina	N/A
Not Yet Recruiting	A Community Health Worker Intervention to Improve Lung Cancer Screening Uptake in Community Health Centers NCT07168629	Baystate Medical Center	N/A
Completed	Responses of Adults Smoking Nondaily and Daily in the Experimental Tobacco Marketplace NCT06988371	Bethany Shorey Fennell	N/A
Recruiting	Developing a Scalable Tobacco Cessation Program for Cancer Survivors and Caregivers NCT06851936	University of Florida	N/A
Recruiting	CONNECT Cancer Survivors With Tobacco Treatment NCT07020273	Washington University School of Medicine	N/A
Recruiting	Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration NCT05999383	University of California, San Francisco	Phase 2
Enrolling By Invitation	Can Cognitive Behavioural Therapy Help Incarcerated Men Quit Smoking? Efficacy and Predictors of Treatment Out NCT06873009	Centre Hospitalier St Anne	N/A
Completed	Oral Nicotine Pouch Marketing Features Influence on Perceptions NCT06605924	Johns Hopkins Bloomberg School of Public Health	N/A
Recruiting	Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse NCT06609369	Yale University	Phase 2
Recruiting	Opioids, Low Nicotine Cigarettes, and Chronic Pain NCT06747871	Duke University	N/A
Recruiting	Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux NCT06746623	Louis Stokes VA Medical Center	N/A
Recruiting	Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS NCT07108166	Philip Morris Products S.A.	N/A
Recruiting	Effect of Cannabis on E-Cigarette Use Behavior NCT06609109	Johns Hopkins University	Phase 1
Recruiting	Reach Through Equitable Implementation in Utah NCT06881069	University of Utah	N/A
Completed	Modern Nicotine Oral Product Abuse Liability NCT06777784	RAI Services Company	N/A
Recruiting	Effect of Cannabis on Cigarette Use Behavior NCT06609083	Johns Hopkins University	Phase 1
Active Not Recruiting	E-cigarette Switching Older Adults NCT06534905	University of Maryland, Baltimore	N/A
Recruiting	A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home NCT06693700	Memorial Sloan Kettering Cancer Center	N/A
Enrolling By Invitation	Salvation Army Tobacco Quit Line Referral Implementation Trial NCT06689774	University of Wisconsin, Madison	N/A
Recruiting	Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures NCT06295757	Masonic Cancer Center, University of Minnesota	N/A
Recruiting	Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers NCT06372899	Abramson Cancer Center at Penn Medicine	N/A
Terminated	Remote Trial - Tobacco Product Standard (VLNC) NCT06442384	Masonic Cancer Center, University of Minnesota	N/A
Recruiting	The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers NCT06264154	Abramson Cancer Center at Penn Medicine	N/A
Completed	CSD231005 Nicotine Pouch Biomarkers of Exposure NCT06303115	RAI Services Company	N/A
Enrolling By Invitation	Modeling Tobacco Regulatory Impacts in Appalachia Using the Experimental Tobacco Marketplace NCT06234722	Mikhail N Koffarnus	N/A
Completed	Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking NCT06546618	UNC Lineberger Comprehensive Cancer Center	N/A
Recruiting	The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Maligna NCT06535867	Memorial Sloan Kettering Cancer Center	—
Recruiting	Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study NCT07447362	Universidad Católica San Antonio de Murcia	N/A
Completed	Chatbot Counselling for Smoking Cessation in Youths NCT06470776	The University of Hong Kong	N/A
Recruiting	Impact of Semaglutide on Tobacco Use and Related Health Behaviors NCT06986993	University of Oklahoma	Phase 4
Recruiting	Developing a Positive Approach to Substance Use Prevention in North American Indian Adolescents NCT05380765	University of Rhode Island	N/A
Completed	Room Air Levels of Harmful and Potentially Harmful Constituents After Heated Tobacco Product Use and Cigarette NCT06476405	Altria Client Services LLC	—
Completed	Tobacco Cessation at FDNY NCT05997225	Albert Einstein College of Medicine	Phase 4
Recruiting	Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation NCT06438549	Loma Linda University	N/A
Completed	Attitudes and Smoking Perceptions in the Real Environment NCT06617520	University of Oklahoma	N/A
Recruiting	Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes NCT05642715	Montefiore Medical Center	N/A
Completed	Feasibility Study - Filter Ventilation NCT04514471	Masonic Cancer Center, University of Minnesota	N/A
Completed	Pharmacokinetic and Subjective Effects of Heated Tobacco Products NCT06356610	Altria Client Services LLC	N/A
Recruiting	Journey of Transformation Curriculum for Native American Youth NCT05731713	University of Washington	N/A
Completed	A Mobile App Based Cognitive Dissonance Intervention for Smoking Cessation NCT05797155	Oregon Research Behavioral Intervention Strategies, Inc.	N/A
Enrolling By Invitation	A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research NCT05852860	Abramson Cancer Center at Penn Medicine	N/A
Completed	Pharmacokinetics and Comparative Bioavailability of Nicotine From Two Variants of NP2, NP2-4mg and NP2-6mg, Co NCT06171490	Philip Morris Products S.A.	N/A
Completed	Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Pr NCT06179290	Altria Client Services LLC	N/A
Unknown	FRESHAIR4Life: Building the Case for Action NCT06074939	Leiden University Medical Center	—
Recruiting	Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement NCT06033599	Rutgers, The State University of New Jersey	Phase 3
Enrolling By Invitation	Enhancing Equity in Smoke-free Housing NCT06042361	Harvard School of Public Health (HSPH)	N/A
Completed	Randomized Controlled Trial to Evaluate the Impact of ZYN Nicotine Pouch Products on Cigarette Usage and BoExp NCT06568900	Swedish Match AB	N/A
Completed	Health and Wellness After Preterm Birth NCT05756634	Children's Hospital of Philadelphia	N/A
Completed	Predictors and Consequences of Combustible Cigarette Smokers' Switch to Standardized Research E-Cigarettes NCT03277495	University of Illinois at Chicago	N/A
Unknown	Characterization of the Pattern of Consumption and Withdrawal Syndrome From Dual Cannabis and Tobacco Use NCT05512091	Cristina Martínez Martínez	—
Completed	Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs NCT05849051	UNC Lineberger Comprehensive Cancer Center	N/A
Completed	Integrating Tobacco Use Cessation Into HIV Care and Treatment in Kisumu County, Kenya NCT05351606	University of California, San Francisco	Phase 4
Active Not Recruiting	A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Di NCT05671380	University of Minnesota	N/A
Completed	Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder NCT05796791	Medical University of South Carolina	EARLY_Phase 1
Recruiting	Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior NCT05572671	Penn State University	N/A
Recruiting	Cardiovascular Effects of Very Low Nicotine Content Cigarettes NCT05707871	Wake Forest University Health Sciences	EARLY_Phase 1
Recruiting	Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia NCT05724810	Stony Brook University	N/A
Recruiting	Overcoming Nicotine Dependence to Enable Quitting NCT05513872	Rush University Medical Center	Phase 1 / Phase 2
Withdrawn	Effect of Switching From Cigarette Smoking to THS on Systemic Endothelial Function in Subjects With Establishe NCT05566678	Philip Morris Products S.A.	N/A
Completed	A Brief Digital Screening Tool to Address Tobacco and E-cigarette Use in Pediatric Medical Care NCT05366790	St. Justine's Hospital	N/A
Completed	Nicotine Pharmacokinetics and Subjective Effects of Oral Nicotine Products Relative to Smokeless Tobacco in Ad NCT06691386	Altria Client Services LLC	N/A
Terminated	Effect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects Wit NCT05569005	Philip Morris Products S.A.	N/A
Completed	QuitGuide for American Indians: Aims 2 & 3 NCT05447156	Masonic Cancer Center, University of Minnesota	N/A
Completed	The Abuse Liability of a Novel Heated Tobacco Product (IQOS) and Its Feasibility as a Menthol Cigarette Substi NCT05499377	Virginia Commonwealth University	N/A
Completed	Reduced Exposure to HPHC in Smokers Switching From Cigarettes to Different Versions of THS NCT05599451	Philip Morris Products S.A.	N/A
Unknown	Choose2Quit: Improving Equity in Smoking Cessation for Low Income Adults NCT05612152	Oregon Health and Science University	N/A
Recruiting	Oral Cannabidiol for Tobacco Cessation NCT05445804	Johns Hopkins University	Phase 1
Completed	Testing Legally Feasible Options Studies 2/3 NCT05604508	RAND	N/A
Enrolling By Invitation	Persistent Poverty Counties Pregnant Women With Medicaid NCT05415371	University of Oklahoma	N/A
Terminated	Journey of Transformation Curriculum for Native American Adolescents NCT05274217	University of Washington	N/A
Completed	Effects of an Oral Nicotine Product in Smokeless Tobacco Users NCT05280769	Virginia Commonwealth University	N/A
Active Not Recruiting	Teachable Moment to Opt-out of Tobacco: Interactive Voice Response Quit Line for Veteran Active Smokers With L NCT04574518	VA Office of Research and Development	N/A
Completed	Quit or Switch: E-cigarette Study NCT05525078	Medical University of South Carolina	N/A
Completed	Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM) NCT05320887	Wake Forest University Health Sciences	N/A
Completed	Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use- Electronic Spanish Platform NCT05476588	Baylor Research Institute	N/A
Completed	Improving Tobacco Treatment Rates for Cancer Patients Who Smoke NCT04738643	Abramson Cancer Center at Penn Medicine	N/A
Completed	CSD200902: Assessment of Indoor Air Quality for a Heated Tobacco Product With Four Non-Combusted Cigarette Var NCT05363254	RAI Services Company	N/A
Completed	Tobacco Cessation Treatment Preferences Among Veteran Smokers NCT05277207	VA Office of Research and Development	Phase 4
Completed	CSD201301: Study to Assess Elements of Abuse Liability for Four P13 Nicotine Pouches NCT05294497	RAI Services Company	N/A
Completed	CSD210903: A Study to Determine Subject Puffing Patterns of a Heated Tobacco Product With Four Non-Combusted C NCT05307822	RAI Services Company	N/A
Active Not Recruiting	Development of UP2UTobacco for High School Youth NCT05396911	University of Virginia	N/A
Completed	Responses to Regulated E-Cigarette Advertisements NCT05207033	University of Massachusetts, Worcester	N/A
Unknown	Examining Effects of Domain Specific Episodic Future Thinking on Cannabis Use NCT05324813	Michael Sofis	N/A
Completed	Media Literacy for High School Tobacco Prevention NCT05120466	University of Pittsburgh	N/A
Completed	CSD201201: Study to Assess Elements of Abuse Liability for Electronic Nicotine Delivery System P12 NCT05210699	RAI Services Company	N/A
Completed	CSD201202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery System P12 NCT05239884	RAI Services Company	N/A
Completed	Pittsburgh and Rural Area High School Tobacco Prevention NCT05081843	University of Pittsburgh	N/A
Completed	Sugars in Cigarettes NCT05308316	Masonic Cancer Center, University of Minnesota	N/A
Completed	CSD201203: A Study to Determine Subject Puffing Patterns of a Non-cylindrical, Closed, Electronic Nicotine Del NCT05118139	RAI Services Company	N/A
Terminated	Testing Feasibility of Care Coordination and Motivational Interviewing for Women With a Recent Preterm Birth NCT05120843	Children's Hospital of Philadelphia	N/A
Completed	CSD201004: An Actual Use Study of P10 and P13 Nicotine Pouches Among U.S. Adult Smokers NCT05184920	RAI Services Company	—
Completed	BAT3221032: A Study to Evaluate the Effects of Switching From Cigarette Smoking to Using One of Five Variants NCT05142436	British American Tobacco (Investments) Limited	N/A
Completed	Identify the Usefulness of In-person and Virtual Quit Smoking Programs NCT05181072	Morgan State University	N/A
Completed	CSD200907: A Study to Assess Elements of Abuse Liability for a Heated Tobacco Product With Four Non-Combusted NCT05114863	RAI Services Company	N/A
Active Not Recruiting	Implementing Tobacco Use Treatment in HIV Clinics Vietnam NCT05162911	New York University	N/A
Completed	Be A Quitter: Illinois Small Business EX Program Dissemination NCT07097194	University of Illinois at Urbana-Champaign	N/A
Completed	Mixed Presentation on Social Media NCT05066126	University of Pennsylvania	N/A
Completed	CSD201001: Study to Assess Elements of Abuse Liability for Three Nicotine Pouches NCT05129657	RAI Services Company	N/A
Completed	CSD210904: Study to Assess Actual Use of a Heated Tobacco Product With Four Non-Combusted Cigarette Variants i NCT05102786	RAI Services Company	—
Completed	Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine NCT05030194	Roswell Park Cancer Institute	N/A
Completed	CSD201002: Study to Assess Nicotine Uptake From P10 Nicotine Pouches NCT05081154	RAI Services Company	N/A
Completed	The Effect of Sweet Flavoring on the Rewarding and Reinforcing Value of Cigarillo Use Among Young Adults NCT05092919	University of Pennsylvania	EARLY_Phase 1
Completed	The Effects of IQOS Use on Cigarette Smoking Behaviors NCT05076708	University of Pennsylvania	EARLY_Phase 1
Unknown	Strategies to Connect Patients at Federally Qualified Health Clinics With Evidence Based Tobacco Cessation Tre NCT03900767	University of Utah	N/A
Completed	Patient Navigation-based Tobacco Harm Reduction Program Among Cancer Patients NCT04972916	Milton S. Hershey Medical Center	N/A
Completed	Project HEALS (Helping and Empowering pAtients for Living a Life Smoke-free NCT05362318	H. Lee Moffitt Cancer Center and Research Institute	N/A
Withdrawn	NYCHA Mindfulness-based Smoking Cessation Intervention NCT04334187	NYU Langone Health	N/A
Completed	Telehealth-Filter Ventilation ( COMET2P1 ) NCT04969783	Masonic Cancer Center, University of Minnesota	N/A
Active Not Recruiting	The Effect of Tobacco Products on Wound Healing NCT04870970	University of Minnesota	—
Completed	Improving Tobacco Treatment Rates for Outpatient Cancer Patients Who Smoke NCT04737031	Abramson Cancer Center at Penn Medicine	N/A
Recruiting	RTMS Targets Neural Circuits for Smoking Cessation NCT04903028	Medical University of South Carolina	N/A
Completed	Study to Evaluate Changes in Smokers Using on!® Nicotine Pouches NCT05664672	Altria Client Services LLC	N/A
Completed	A Study to Characterize Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouches in Adult Cigarett NCT04846088	British American Tobacco (Investments) Limited	N/A
Completed	Pilot Randomised Controlled Trial of ToQuit Intervention in India NCT04782453	Sangath	N/A
Enrolling By Invitation	Tobacco-Concurrent Addictions in At-Risk Youth in Ottawa NCT04812613	Ottawa Hospital Research Institute	—
Unknown	Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers NCT04722835	University of California, San Francisco	—
Completed	CSD210202: A Study to Assess Nicotine Uptake From Electronic Nicotine Delivery Systems NCT04751461	RAI Services Company	N/A
Completed	Digital Media for Cancer Control (to Prevent Vaping and Smoking Behavior) NCT04867668	George Washington University	N/A
Completed	A Study to Assess the Pharmacokinetics of Oral Nicotine Pouches and Lozenges in Healthy Adults NCT04755348	British American Tobacco (Investments) Limited	N/A
Unknown	Eliciting Perceived Norms About Substance Use NCT04833972	Massachusetts General Hospital	N/A
Completed	CORE: CO Monitoring for Reach and Efficacy in Tobacco Treatment for Cancer Patients NCT04675515	Dartmouth-Hitchcock Medical Center	N/A
Completed	Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Stud NCT04646174	Rush University Medical Center	N/A
Completed	Lung Cancer Screening Navigation for Homeless People NCT04308226	Massachusetts General Hospital	N/A
Completed	THC Crossover Study NCT04429568	University of California, San Francisco	N/A
Completed	Shrinking the Size of the Tobacco Power Wall NCT04632030	RAND	N/A
Completed	Smartphone Application Smoking Cessation Study NCT04623736	University of Virginia	N/A
Unknown	Tobacco Cessation Among Smokers Under Alcohol and/or Cannabis Treatment NCT04841655	Institut Català d'Oncologia	—
Completed	Families With Substance Use and Psychosis: A Pilot Study NCT04284813	Mclean Hospital	N/A
Completed	Smoking in the Paris Fire Brigade and Comparison According to the Type of Service (Permanent or On-call) NCT04566198	Direction Centrale du Service de Santé des Armées	—
Completed	IQOS (Non-Cigarette Tobacco Product) Pilot Study NCT04357379	Medical University of South Carolina	N/A
Completed	Salt-Based E-cigarette NCT04238832	Medical University of South Carolina	N/A
Enrolling By Invitation	Antibiotic Prophylaxis in High-Risk Arthroplasty Patients NCT04297592	Mayo Clinic	Phase 4
Completed	CSD190601: A Study to Determine Subject Puffing Patterns of Electronic Nicotine Delivery Systems in an Ambulat NCT04308434	RAI Services Company	N/A
Completed	CSD190401: A Study to Assess Elements of Abuse Liability for Nicotine-containing Pouch Tobacco Products NCT04372290	RAI Services Company	N/A
Completed	Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment NCT04461288	University of California, San Francisco	N/A
Unknown	Effectiveness of Tobacco Cessation Interventions in Sweden NCT04819152	Lund University	—
Suspended	Influence of Tobacco Use on Cannabis Use NCT03766971	New York State Psychiatric Institute	Phase 2
Unknown	Comparative Tobacco Interventions for Individuals With Severe and Persisting Behavioral Health Disorders NCT04523948	Rose Research Center, LLC	—
Completed	Testing Legally Feasible Options: Study 1 NCT04259749	RAND	N/A
Completed	Reducing Tobacco Exposures Among African American Women and Children NCT03476837	University of Arkansas	N/A
Completed	CSD190501: A Study to Determine Subject Puffing Patterns of an Electronic Nicotine Delivery System in an Ambul NCT04226404	RAI Services Company	N/A
Unknown	Screening While You Wait 2: Alcohol and Tobacco Use NCT04594304	Women's College Hospital	N/A
Completed	Connecting Alaska Native People to Quit Smoking NCT03645941	Mayo Clinic	N/A
Completed	CSD190301: A Study to Assess Elements of Abuse Liability for Two Dissolvable Nicotine Lozenge Tobacco Products NCT04167384	RAI Services Company	N/A
Completed	JUUL vs. Mod E-cigarette Study NCT04237272	Medical University of South Carolina	N/A
Completed	CSD190203: A Study to Determine Subject Puffing Patterns of an Electronic Nicotine Delivery System in an Ambul NCT04104152	RAI Services Company	N/A
Completed	Evaluating Selected Constituents in the Exhaled Breath Samples NCT04143256	Juul Labs, Inc.	N/A
Completed	CSD190202: Study to Assess Elements of Abuse Liability for Two Electronic Nicotine Delivery Systems NCT04094363	RAI Services Company	N/A
Withdrawn	A Community-University Approach to Preventing HIV NCT03938077	University of Michigan	N/A
Completed	Expanding the Click City Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products NCT03682900	Oregon Research Behavioral Intervention Strategies, Inc.	N/A
Withdrawn	Effects of Electronic Cigarettes in Cigarette Smokers With Mild to Moderate COPD NCT03379025	Massachusetts General Hospital	N/A
Completed	Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to JUUL ENDS NCT04107779	Juul Labs, Inc.	N/A
Completed	Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start Study NCT04043728	Rush University Medical Center	N/A
Active Not Recruiting	Comparing an Opt-out to an opt-in Approach for Smoking Cessation in VA Primary Care Clinics NCT03477435	VA Office of Research and Development	N/A
Completed	CSD190101: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products NCT03993769	RAI Services Company	N/A
Completed	CSD190102: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products NCT03993782	RAI Services Company	N/A
Completed	CSD190103: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products NCT03993795	RAI Services Company	N/A
Withdrawn	The Impact of E-liquid Nicotine Content on Reinforcement in Current Smokers NCT03186911	Wake Forest University Health Sciences	N/A
Terminated	Impact of Cigarette and E-cigarette Flavors on Adult Smoking Behavior NCT04009850	Yale University	N/A
Withdrawn	E-Cigarette and Cigarette Nicotine Delivery and Abuse Liability in Cigarette Smokers and Dual Users NCT03943706	University of Oklahoma	—
Completed	BRP1802 Smoking Abstinence Study NCT04979013	RAI Services Company	N/A
Completed	Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment NCT03612804	VA Office of Research and Development	N/A
Completed	Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI) NCT03873337	Rutgers, The State University of New Jersey	N/A
Completed	Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns NCT03844672	Medical University of South Carolina	N/A
Completed	E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease NCT03863509	University of Wisconsin, Madison	—
Completed	Electronic Cigarette Unit Price Manipulations in the Experimental Tobacco Marketplace NCT03843047	Virginia Polytechnic Institute and State University	N/A
Completed	Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation NCT03734666	H. Lee Moffitt Cancer Center and Research Institute	N/A
Completed	Jail-Based Use of Smoking Cessation Treatment Study NCT03799315	Hennepin Healthcare Research Institute	N/A
Completed	Connection to Health for Smokers NCT03680599	University of California, San Francisco	N/A
Completed	Clinical Study Comparing 7 ENDS Products and 1 Combustible Cigarette Using 2 Delivery Methods. NCT03700112	Juul Labs, Inc.	N/A
Completed	Baby Albert: Electronic Cigarette Pharmacokinetics (PK) and Abuse Liability NCT03637452	University of Oklahoma	—
Completed	An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers NCT03553992	University of California, San Francisco	N/A
Completed	CSD1805: Study to Assess Nicotine Uptake and Product Use Behavior in Moist Snuff Consumers Using Two Moist Snu NCT03688776	RAI Services Company	N/A
Completed	United States Pre-Market Tobacco Application Pharmacokinetics NCT03719391	Juul Labs, Inc.	N/A
Completed	COMET2 Project 1 Filter Ventilation Study NCT03637972	Masonic Cancer Center, University of Minnesota	Phase 3
Completed	A Study to Characterize Puff Topography With Use of JUUL 5% Electronic Nicotine Delivery Systems (ENDS) in Adu NCT03596034	Juul Labs, Inc.	N/A
Unknown	Assessing Tobacco Product Choice When the Cost of Menthol Cigarettes Increases NCT03612349	Brown University	N/A
Completed	Evaluating and Improving the Sustainability of State-level Tobacco Control Programs in the United States NCT03598114	Washington University School of Medicine	N/A
Completed	Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers NCT03593239	Juul Labs, Inc.	N/A
Completed	A Study to Assess Changes in Cigarette Consumption During a Switch to Very Low Nicotine Cigarettes NCT03571724	22nd Century Group, Inc.	N/A
Completed	A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products. NCT03692078	Altria Client Services LLC	N/A
Completed	Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial (CONNECT) NCT03453385	Medical University of South Carolina	N/A
Completed	A Laboratory Model of Increasing Delta-9-tetrahydrocannabinol (THC) Potency on Cigarette Smoking NCT02961309	Battelle Memorial Institute	Phase 1
Completed	Evaluation of Abuse Liability of Very Low Nicotine (VLN) Mentholated Cigarettes NCT03559725	22nd Century Group, Inc.	Phase 1
Completed	A Guided Imagery Tobacco Cessation Intervention Delivered by a Quit Line and Website NCT02968381	University of Arizona	N/A
Completed	A Facebook Intervention for Young Sexual and Gender Minority Smokers NCT03259360	University of California, San Francisco	N/A
Completed	Evaluation of the Abuse Liability of Very Low Nicotine (VLN) Cigarettes NCT03559751	22nd Century Group, Inc.	Phase 1
Terminated	Cross-Sectional Survey on the Use of Tobacco Products - Italy NCT03527004	Philip Morris Products S.A.	—
Terminated	Cross-Sectional Survey on the Use of Tobacco Products - Germany NCT03527017	Philip Morris Products S.A.	—
Terminated	Cross-Sectional Survey on the Use of Tobacco Products - London (UK) NCT03527030	Philip Morris Products S.A.	—
Completed	Identify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult Smokers NCT03463837	Juul Labs, Inc.	N/A
Unknown	Investigation of Cigarette Cravings in Smokers NCT04843969	Marco Leyton	N/A
Completed	Electronic Cigarette Use in Young Adult Men and Women NCT03089541	Yale University	N/A
Terminated	Electroretinogram: a New Human Biomarker for Smoking Cessation Treatment NCT03213418	New York State Psychiatric Institute	N/A
Active Not Recruiting	Post Acute Cardiac Event Smoking (PACES) Study NCT03413423	Hennepin Healthcare Research Institute	N/A
Completed	Faith Based Pilot Intervention to Reduce Tobacco Use Among Somali Males NCT03379142	University of Minnesota	N/A
Terminated	Pregnancy, Mindfulness, and Massage NCT03276208	Yale University	N/A
Unknown	Address Tobacco Use Among Adolescents in Hong Kong NCT03264144	The University of Hong Kong	N/A
Unknown	Tobacco Use and Uptake of COVID-19 Vaccinations NCT05479383	Finnish Institute for Health and Welfare	—
Withdrawn	Mechanisms of Ethnic/Racial Differences in Lung Cancer Due to Cigarette Smoking Clinical and Biomarkers Core NCT03352635	University of Minnesota	—
Completed	EMA for Tobacco Control Policy Research NCT03235713	The University of Hong Kong	—
Completed	Provider Training in Increasing Patient Tobacco Cessation Counseling and Referrals for Patients With Cancer Un NCT03135782	OHSU Knight Cancer Institute	N/A
Completed	Helping Poor Smokers Quit NCT03194958	Washington University School of Medicine	N/A
Completed	CSD170201: A Study to Evaluate the Exposure to Tobacco Constituents From Two Moist Snuff Products NCT03153761	RAI Services Company	N/A
Completed	CSD170202: A Study to Evaluate the Exposure to Tobacco Constituents From Two Moist Snuff Products NCT03158428	RAI Services Company	N/A
Completed	The Lung Screening, Tobacco and Health Project NCT03200236	Georgetown University	Phase 3
Completed	Evaluation of a Brief Tobacco Intervention in the US Military NCT03196102	University of Virginia	N/A
Completed	Minocycline and Tobacco Craving in Smokers With Schizophrenia NCT02968602	University of Maryland, Baltimore	Phase 4
Completed	Characterization of Selected Aerosol Constituents Levels in the Exhaled Breath of Adult e-Vapor Users NCT04881942	Altria Client Services LLC	N/A
Completed	Impact of Switching to Non-Menthol Cigarettes Among Smokers NCT03075839	Yale University	N/A
Completed	Mobile-based Peer Mentoring for Smoking Cessation NCT03048786	University of California, San Francisco	N/A
Unknown	Tobacco Treatment TrAining Network in Greece & Cyprus NCT03040349	University of Crete	N/A
Withdrawn	Integrated Smoking Cessation and Mood Management for ACS Patients NCT03029923	The Miriam Hospital	N/A
Completed	Biomarkers of Exposure and Biomarkers of Potential Harm in Adult Smokers Who Completely Switch to E-vapor Prod NCT04800211	Altria Client Services LLC	N/A
Completed	Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention NCT03855410	University of Michigan	N/A
Completed	BRP1602: Evaluation of Technical and Logistical Feasibility to Measure Lung Permeability NCT06105424	RAI Services Company	N/A
Completed	Air Quality Feedback to Reduce Second-hand Smoke (SHS) Exposure in the Home NCT03151421	Institut Català d'Oncologia	N/A
Completed	Metabolism-informed Care for Smoking Cessation NCT03227679	Vanderbilt University Medical Center	N/A
Completed	CSD1601: A Study to Evaluate the Exposure to Tar and Nicotine From Two Cigarette Products That Contain a Menth NCT04529551	RAI Services Company	N/A
Completed	Snuff Use, Smoking, Periodontitis and Mortality: 30-year Cohort Study From Sweden NCT03918902	University of Helsinki	—
Completed	Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study NCT03614871	University of Helsinki	—
Completed	A Mobile Intervention to Promote Cessation in HIV-infected Smokers NCT02432482	Montefiore Medical Center	N/A
Completed	QuitAdvisorDDS: A Point-of-Care Tobacco Cessation Tool for Dental Settings NCT02570646	Jamie Studts	N/A
Completed	Pediatric Health Promotion Program NCT03322501	Georgetown University	N/A
Completed	The Effect of AAT Training in Smokers NCT02481752	University of Texas at Austin	N/A
Completed	Policy-Related Survey - Territory-wide Telephone Survey on Tobacco Control NCT02760550	The University of Hong Kong	—
Completed	Smoking Cessation for Cervical Cancer Survivors NCT02157610	H. Lee Moffitt Cancer Center and Research Institute	N/A
Completed	Expansion of the COPD At-risk Module in 4 States BRFSS Telephone Health Surveys NCT02991391	Duke University	—
Completed	Employee Wellness Survey NCT02673346	Mayo Clinic	—
Completed	Effect of Cigarette Pack Warnings and Packaging Among Young Adult Smokers NCT03446170	Georgetown University	N/A
Completed	Influence of Tobacco Smoking on the Development of Obstructive Sleep Apnea (OSA) NCT03574740	Astes	—
Completed	Biomarker Feedback to Motivate Tobacco Cessation in Pregnant ALaska Native Women: Phase 2 NCT02018640	Mayo Clinic	—
Completed	A Study to Evaluate Changes in Smokers Using An Oral Tobacco-Derived Nicotine Product NCT04079933	Altria Client Services LLC	N/A
Completed	Smoking Cessation for Young Adult Pacific Islanders: Motivating Pacifika Against Cigarettes and Tobacco NCT03238456	Claremont Graduate University	N/A
Unknown	Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers NCT01892813	Mark Vander Weg	Phase 3
Completed	Substance Use and Lifestyle-related Health Problems in Ageing Patients in OMT Treatment NCT05182918	Sorlandet Hospital HF	—
Completed	Practice-based Intervention for Vietnamese and Korean Patients NCT03064724	Asian Health Services	N/A
Completed	Biomarker Feedback to Motivate Tobacco Cessation in Pregnant Alaska Native Women NCT01605643	Mayo Clinic	—
Completed	Effectiveness of a School-based Tobacco Prevention Program for Middle School Students in Saudi Arabia NCT03579355	King Abdulaziz University	N/A
Completed	Tobacco Impact on Quality of Life on Snus-use, Dual Use, Smoke Use and Non-using. NCT05409963	Vastra Gotaland Region	—
Completed	Effect of a Perioperative Smoking Cessation Program on Smoking Cessation/Reduction and Perioperative Complicat NCT01260233	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's	N/A
Completed	Testing Counseling Styles to Motivate Smokers to Quit NCT01188018	University of Missouri, Kansas City	Phase 3
Completed	Effectiveness of Pedialink CEASE Module NCT01087177	Massachusetts General Hospital	N/A
Completed	Asian Youth and Tobacco Control Survey NCT00642317	M.D. Anderson Cancer Center	—
Completed	Smoking Cessation Program Among Adolescents in Vocational Training Centers NCT00973570	Institut National de la Santé Et de la Recherche Médicale, France	N/A
Completed	Gabapentin for Smoking Cessation NCT00578552	Mayo Clinic	Phase 2
Completed	Enhancing Smoker Utilization of the Minnesota Quitline Through Support Persons NCT01311830	Mayo Clinic	N/A
Completed	Interactive Psychopharmacologic Effects of Alcohol and Nicotine in Humans NCT00616746	Yale University	EARLY_Phase 1
Withdrawn	Monitoring and Outcome Measures in Asthmatics and Smokers During Pregnancy NCT00425880	University of Kentucky	—
Completed	Tobacco Cessation Treatment for Pregnant Alaska Natives NCT00379444	Mayo Clinic	Phase 1 / Phase 2
Completed	Telephone and Web-based Teen Tobacco Cessation in HMOs NCT00311948	Kaiser Permanente	Phase 3
Completed	Strategies to Help Adult ED Patients Quit Smoking NCT00297466	National Institute on Drug Abuse (NIDA)	N/A
Completed	Emergency Department Initiated Tobacco Treatment (EDITT) NCT00252902	National Institute on Drug Abuse (NIDA)	Phase 1 / Phase 2
Completed	A Study to Examine Health Behavior Change Strategies for Primary Care NCT01323023	University of Colorado, Denver	—
Completed	An Intervention to Address Parental Smoking During the Postpartum Hospitalization. NCT00844818	Massachusetts General Hospital	N/A
Terminated	Early Tobacco Abstinence - 5 NCT00224965	National Institute on Drug Abuse (NIDA)	Phase 1