NCT07020273

CONNECT Cancer Survivors With Tobacco Treatment

Cancer Prevention by Reducing Tobacco With Informatics and Chronic Care Approaches Trial (CONNECT)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 5,000 (estimated)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the comparative effectiveness of two different informatics-enabled implementation strategies on increasing tobacco treatment and improving smoking cessation rates for cancer control and prevention. This will be done via a two-arm pragmatic cluster randomized trial (CRT) to test the effectiveness of nudges to change (ELEVATE-S) vs. quit-focused usual care (ELEVATE) in increasing tobacco treatment (use of medication, brief advice, or referral to external counseling) and smoking cessation.

Conditions

• Tobacco Use
• Tobacco Use Cessation
• Smoking Cessation
• Nicotine Addiction
• Tobacco Smoking

Interventions

Type	Name	Description
BEHAVIORAL	ELEVATE	ELEVATE uses implementation strategies to support clinicians (support clinicians by revising professional roles to enable point of care tobacco treatment with a team are approach and support clinicians by providing clinical decision support tools).
BEHAVIORAL	ELEVATE-S	ELEVATE-S uses implementation strategies to support clinicians (support clinicians by revising professional roles to enable point of care tobacco treatment with a team are approach and support clinicians by providing clinical decision support tools) and implementation strategies to support patients with chronic care model-informed self-management support (patient centered flexible goals and patient-generated health data).

Timeline

• Start date: 2025-07-01
• Primary completion: 2027-01-01
• Completion: 2027-01-01
• First posted: 2025-06-13
• Last updated: 2026-01-08

Locations

1 site across 1 country: United States