| Not Yet Recruiting | Addressing Parental Tobacco Use in Somali Immigrant Families: Adapting an Evidence-Based Intervention in Prima NCT06839729 | University of Minnesota | Phase 1 |
| Not Yet Recruiting | Developing Empowering Smoking Cessation NCT06602076 | University of Oklahoma | EARLY_Phase 1 |
| Not Yet Recruiting | A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric NCT07398404 | Yale University | Phase 1 / Phase 2 |
| Not Yet Recruiting | Smoking Cessation Program for Lao People With HIV NCT07014605 | University of Oklahoma | N/A |
| Not Yet Recruiting | My Path to Quit Tobacco NCT07419425 | University of Wisconsin, Madison | Phase 4 |
| Not Yet Recruiting | Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults NCT07507435 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Not Yet Recruiting | Telegram Messenger Support for Smoking Cessation After Heart Attack NCT07230249 | ITMO University | N/A |
| Not Yet Recruiting | PASCAL Feasibility Study NCT07301151 | University of Minnesota | N/A |
| Not Yet Recruiting | Rural Smoking Cessation NCT06584929 | Masonic Cancer Center, University of Minnesota | N/A |
| Recruiting | Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites NCT06837220 | University of Chicago | N/A |
| Not Yet Recruiting | A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation NCT07487818 | Mayo Clinic | Phase 2 / Phase 3 |
| Recruiting | Preliminary Effectiveness of Enhanced Text Message + Incentives NCT07420621 | University of Kansas Medical Center | N/A |
| Not Yet Recruiting | Quit-Smoking Study for Native Hawaiians NCT07075575 | University of Hawaii | N/A |
| Not Yet Recruiting | Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum NCT07489443 | University of Pittsburgh | N/A |
| Not Yet Recruiting | Pain and Smoking Study - Interactive Voice Response NCT06442514 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study) NCT07145866 | Massachusetts General Hospital | Phase 4 |
| Recruiting | Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients NCT07224087 | Yale University | Phase 1 |
| Not Yet Recruiting | Mobile Health (mHealth) Application for Smoking Cessation Among Adolescents in Indonesia NCT07198828 | Gadjah Mada University | N/A |
| Not Yet Recruiting | Health Communications for Adults Smoking Nondaily NCT07296848 | Bethany Shorey Fennell | N/A |
| Not Yet Recruiting | Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Ces NCT07099638 | University of Oklahoma | Phase 2 |
| Recruiting | Quitxt Mobile Text Messaging Cessation Research Study NCT05958667 | The University of Texas Health Science Center at San Antonio | N/A |
| Enrolling By Invitation | Engaging Pharmacists to Advance Tobacco Treatment Service Delivery NCT07501624 | Medical University of South Carolina | N/A |
| Enrolling By Invitation | Developing a Community Support Program to Help People Quit Smoking. NCT07432152 | Mahidol University | N/A |
| Recruiting | Integrating Smoking Cessation With Low-dose CT-screening for Lung Cancer NCT07331519 | Oulu University Hospital | N/A |
| Not Yet Recruiting | Testing an MBI for Smoking Cessation and Alcohol Use Among Cancer Survivors NCT07447635 | H. Lee Moffitt Cancer Center and Research Institute | N/A |
| Not Yet Recruiting | Evaluating the Impact of CONNECT in a Multilingual Population NCT07111936 | University of California, San Francisco | N/A |
| Recruiting | Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors NCT07210567 | Rutgers, The State University of New Jersey | N/A |
| Not Yet Recruiting | Improving Lifestyle Habits and Metabolic Health in Forensic Psychiatric Patients NCT07157813 | Kronoberg County Council | N/A |
| Not Yet Recruiting | Xylitol Gum for Promoting Smoking Cessation NCT07240545 | The University of Hong Kong | N/A |
| Recruiting | Trauma-Informed Care for Smoking Cessation for Pregnancy NCT07129590 | University of California, San Francisco | N/A |
| Recruiting | Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT) NCT06556238 | Southcentral Foundation | N/A |
| Recruiting | ACT Lung Health Intervention: Phase Two NCT06945120 | Dana-Farber Cancer Institute | N/A |
| Active Not Recruiting | Forward to Quit: A Person-centered Mobile Technology Intervention for Smoking Cessation Among Transgender Adul NCT07181551 | University of Colorado, Denver | N/A |
| Not Yet Recruiting | ChatGPT-Supported Text Messaging Program for Smoking Cessation NCT07079306 | George Washington University | N/A |
| Recruiting | Technology Assisted Motivational Interviewing NCT06713603 | University of California, San Francisco | N/A |
| Recruiting | Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients NCT07166120 | Washington University School of Medicine | N/A |
| Enrolling By Invitation | The Researchers Would Like to Conduct a Trial Using Gamified Exercise to Increase Cardiorespiratory Fitness an NCT07390695 | Gadjah Mada University | N/A |
| Not Yet Recruiting | Empowering Cessation ACS South Region NCT06820034 | University of Oklahoma | Phase 1 / Phase 2 |
| Recruiting | Effects of Smoking Addiction on Lower Limb Speed and Coordination NCT07061522 | Saglik Bilimleri Universitesi | — |
| Recruiting | Quitting Matters Human Immunodeficiency Virus Hybrid Trial NCT06883097 | Wake Forest University Health Sciences | N/A |
| Active Not Recruiting | Pharmacist Intervention to Improve Smoking Cessation NCT06943287 | University of Iowa | N/A |
| Recruiting | The Effects of Cigarette Addiction on Lower Extremity Movement Speed and Coordination NCT07075068 | Saglik Bilimleri Universitesi | — |
| Recruiting | Interventions for Maximizing Patient And Family Smoking Cessation Together NCT07267936 | Papworth Hospital NHS Foundation Trust | N/A |
| Recruiting | CONNECT Cancer Survivors With Tobacco Treatment NCT07020273 | Washington University School of Medicine | N/A |
| Active Not Recruiting | Real-time Smoking Cessation Instant Messaging Support Using a Large Language Model (LLM)-Based Chatbot Via "Qu NCT06914492 | The University of Hong Kong | N/A |
| Enrolling By Invitation | Can Cognitive Behavioural Therapy Help Incarcerated Men Quit Smoking? Efficacy and Predictors of Treatment Out NCT06873009 | Centre Hospitalier St Anne | N/A |
| Recruiting | Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos NCT06926608 | University of Rochester | N/A |
| Recruiting | Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities NCT07049757 | University of California, San Francisco | N/A |
| Withdrawn | Developing and Pilot Testing a Remote Smoking Cessation Digital Therapeutic for Individuals With Serious Menta NCT05031416 | Johns Hopkins University | N/A |
| Not Yet Recruiting | Smoking Cessation App. in Arabic NCT06766227 | Yarmouk University | N/A |
| Recruiting | The Options 2 Study NCT06595459 | University of Wisconsin, Madison | Phase 4 |
| Enrolling By Invitation | School-EduSmoke: A Cluster Randomized Controlled Trial for Promoting Smoking Cessation Among Parents of School NCT06853483 | Huazhong University of Science and Technology | N/A |
| Recruiting | New Strategies to Enhance Smoking Cessation NCT06751927 | University of Chicago | N/A |
| Recruiting | American Indian Smokefree Native RCT NCT06544811 | Masonic Cancer Center, University of Minnesota | N/A |
| Not Yet Recruiting | Mobile Smoking Treatment for Hispanic Individuals Who Smoke NCT06586034 | University of Houston | N/A |
| Recruiting | Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy NCT06948058 | Brown University | N/A |
| Recruiting | Creation of an Infrastructure to Support Delivery of mHealth Interventions for Cancer Patients NCT06909357 | H. Lee Moffitt Cancer Center and Research Institute | N/A |
| Recruiting | Smoking Cessation Programme in Workplaces in Hong Kong (Phase ⅤII) NCT06932718 | The University of Hong Kong | N/A |
| Recruiting | tDCS Plus Varenicline for Smoking Cessation NCT06798324 | Centre for Addiction and Mental Health | Phase 4 |
| Not Yet Recruiting | Smoking Cessation Intervention Including Health Navigators to Address Unmet Social Needs of Parents Who Smoke NCT06651684 | St. Justine's Hospital | N/A |
| Recruiting | Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches NCT06678789 | Medical University of South Carolina | N/A |
| Completed | Chewing Gum for Smoking Cessation NCT06801860 | The University of Hong Kong | N/A |
| Recruiting | A Culturally Tailored Smartphone Application for African American Smokers NCT05188287 | University of Oklahoma | N/A |
| Enrolling By Invitation | Effect of Nicotine Gingival Fibroblast Intoxication on the Response of Periodontal Treatment NCT07491627 | University of Liege | N/A |
| Not Yet Recruiting | 12-Month Efficacy of Exercise and Cytisinicline for Tobacco Abstinence NCT06579846 | Maimónides Biomedical Research Institute of Córdoba | Phase 4 |
| Recruiting | Testing the mHealth App Intervention for Nondaily Smokers "SiS4" NCT06678243 | Massachusetts General Hospital | N/A |
| Recruiting | Examining the Effects of Cytisinicline on Neural Substrates of Cigarette Cue-reactivity NCT06617312 | University of California, Los Angeles | Phase 2 |
| Recruiting | Effectiveness of Smoking Cessation Education NCT06930547 | Erzurum Technical University | N/A |
| Recruiting | CONNECTing to LungCare NCT06213532 | University of California, San Francisco | N/A |
| Recruiting | A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home NCT06693700 | Memorial Sloan Kettering Cancer Center | N/A |
| Recruiting | The Effect of Cytisine Treatment for Smoking Cessation on Cardiovascular Function in Adult Smokers NCT06885970 | University of Athens | — |
| Recruiting | Impact of a Counseling Consultation in the Workplace for Smoker Health Professionals NCT06988644 | Groupe Hospitalier Mutualiste de Grenoble | N/A |
| Not Yet Recruiting | A TTM-based Smoking Cessation Intervention in Helping Expectant Fathers to Quit Smoking and Maintain Abstinenc NCT06663475 | Sun Yat-sen University | N/A |
| Enrolling By Invitation | Salvation Army Tobacco Quit Line Referral Implementation Trial NCT06689774 | University of Wisconsin, Madison | N/A |
| Not Yet Recruiting | Effect of Smoking Cessation on Glycemic Control in Type 2 Diabetics NCT06687213 | Assiut University | — |
| Completed | Examining the Efficacy of a Newly Developed Smoking Cessation Program NCT06746025 | Quit Center LLC | — |
| Recruiting | Using Multiphase Optimization Strategy (MOST) to Optimize a Cost-effective, Sustainable and Scalable Smoking C NCT06598397 | New York University | Phase 4 |
| Not Yet Recruiting | PRAMS: Peer-support To Reduce Antenatal Maternal Smoking NCT06595199 | King's College London | N/A |
| Recruiting | Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors NCT05687604 | Northwestern University | N/A |
| Recruiting | The Avenues Study: Dual Use Cessation NCT06474299 | University of Wisconsin, Madison | Phase 4 |
| Completed | VIDeOS for Smoking Cessation NCT06307496 | Medical University of South Carolina | N/A |
| Completed | Advancing Smoking Cessation Among Transgender NCT07099287 | University of Rochester | N/A |
| Recruiting | Contingency Management to Promote Smoking Cessation NCT06456242 | University of Kansas Medical Center | N/A |
| Recruiting | Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household S NCT06582693 | Children's Hospital of Philadelphia | N/A |
| Recruiting | Family-Based Financial Incentives Intervention for Smoking Cessation NCT06556433 | Mayo Clinic | N/A |
| Unknown | Implementation of Lung Cancer Screening in the First Line Zone of ZORA (Flanders), Using a Low Dose CT-scan NCT06293833 | University Hospital, Antwerp | N/A |
| Recruiting | Sumamos Excelencia Project: Implementation of Best Practices in Clinical Practice (Thrid Edition) NCT06522529 | Instituto de Salud Carlos III | N/A |
| Not Yet Recruiting | Mobile Phone-Based Smoking-Cessation Intervention for Smoking Parents NCT06570122 | Beijing Normal University | N/A |
| Not Yet Recruiting | AI-powered Chatbot vs. Human Counselors in Smoking Cessation NCT06570070 | Beijing Normal University | N/A |
| Terminated | Project QUIT+: Adapting and Testing a Smoking Cessation Intervention for Transgender and Gender Expansive Indi NCT06654414 | Massachusetts General Hospital | N/A |
| Completed | Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders NCT06554873 | Rose Research Center, LLC | Phase 3 |
| Completed | Study of a Smartphone-Based Switch Program NCT06544772 | Pivot Health Technologies Inc. | N/A |
| Suspended | SmokefreeSGM Español Pilot, Beta Testing a Text-based Smoking Cessation Intervention for Sexual and Gender Min NCT06487806 | The University of Texas Health Science Center, Houston | N/A |
| Recruiting | Smoking Cessation Intervention for American Indian Women Experiencing Intimate Partner Violence NCT06357767 | Black Hills Center for American Indian Health | N/A |
| Terminated | Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia NCT06374290 | The University of Texas Health Science Center, Houston | Phase 1 |
| Completed | Project HOPES: Healthy Options for Pain and Ending Smoking. A Program for Cancer Survivors. NCT06029907 | Duke University | Phase 4 |
| Completed | Chatbot Counselling for Smoking Cessation in Youths NCT06470776 | The University of Hong Kong | N/A |
| Recruiting | Detour: a Smartphone Game to Help Youth Quit Smoking NCT06675526 | Behavioural Science Institute | N/A |
| Unknown | Comparison of Nicotine Replacement Therapy and Electronic Cigarettes for Smoking Cessation in Pakistan NCT06063421 | Strategic Health Research Limited | N/A |
| Unknown | Effectiveness of Different THR Products in Adult Population NCT05825924 | Foundation for a Smoke Free World INC | Phase 3 |
| Completed | Helping People Adhere to Their Varenicline Treatment by Co-creating a Conversational Agent: A Feasibility Stud NCT05997901 | Centre for Addiction and Mental Health | N/A |
| Completed | Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers NCT06435221 | Achieve Life Sciences | Phase 3 |
| Withdrawn | Video Messages for Smoking Cessation Campaign NCT06284369 | Loma Linda University | N/A |
| Completed | Web-based Smoking Intervention as an add-on to Routine Smoking Cessation Clinical Treatment NCT06945770 | Ege University | N/A |
| Recruiting | Smoking Cessation Program in the Construction Sector NCT06098144 | University of Miami | Phase 4 |
| Completed | Tobacco Exposure and Influencing Factors of Smoking Cessation Among Chronic Kidney Disease Patients NCT06303089 | Sun Yat-sen University | — |
| Completed | Vaping Prevention and Vaping in Youth (Vapechat) NCT06003439 | Boston University | N/A |
| Completed | Tobacco Cessation in Public Housing NCT04889638 | Johns Hopkins University | N/A |
| Recruiting | Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use NCT06027840 | Yale University | Phase 1 |
| Completed | The Effect of Motivational ınterviewing on ıntention to Quit Smoking in Lung Cancer Patients NCT06912113 | University of Gaziantep | N/A |
| Completed | Quit Smoking Text Message Study NCT06111755 | Yale University | N/A |
| Enrolling By Invitation | Rural COPD E-Visit Study NCT06236347 | Medical University of South Carolina | N/A |
| Recruiting | South Africa Smoking Cessation and Engagement in HIV/TB Care Care NCT05842161 | Massachusetts General Hospital | N/A |
| Active Not Recruiting | An Interactive Smartphone Application to Motivate Smokers to Quit NCT05799625 | Ottawa Heart Institute Research Corporation | N/A |
| Recruiting | Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia NCT05660525 | University of Virginia | N/A |
| Recruiting | Phone Enabled Implementation of Cessation Support NCT05628389 | University of Florida | N/A |
| Completed | Treating Caregivers Who Smoke at AFCH NCT06051474 | University of Wisconsin, Madison | Phase 4 |
| Completed | Tobacco Treatment Comparison for Cancer Care NCT06218823 | University of Wisconsin, Madison | Phase 4 |
| Unknown | Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in He NCT06130423 | Poitiers University Hospital | N/A |
| Recruiting | Tobacco Education and Lung Health Study (TEAL) NCT06290869 | Georgetown University | Phase 3 |
| Active Not Recruiting | Smoking Cessation Program for the Older Smokers NCT06234475 | The University of Hong Kong | N/A |
| Completed | Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation NCT04839198 | The University of Texas Health Science Center, Houston | N/A |
| Recruiting | The "Quit-for-Kids" Project: to Increase Abstinence and Protect Children from Tobacco Smoke Exposure NCT06127589 | The University of Hong Kong | N/A |
| Completed | Implementation Science to Reduce the Disparity in Tobacco Treatment Among Individuals With Serious Mental Illn NCT05952401 | Washington University School of Medicine | N/A |
| Completed | Evaluating the Impact of a Photoaging App Versus School-Based Educational Intervention on Adolescents' Knowled NCT06483763 | Sultan Qaboos University | N/A |
| Recruiting | Veteran Social Support for Enhancing Use of Smoking Cessation Treatment NCT05868421 | VA Office of Research and Development | N/A |
| Completed | Translational Research Center in Lung Cancer Disparities (TRACER) Project 2 NCT05490251 | Virginia Commonwealth University | — |
| Recruiting | Concentration Impact Nicotine Salt NCT04725656 | Insel Gruppe AG, University Hospital Bern | N/A |
| Recruiting | Healing Within: Mindfulness Smoking Cessation Intervention NCT07013968 | National Heart, Lung, and Blood Institute (NHLBI) | N/A |
| Completed | Development of Typology-based Smoking Relapse Prevention: A Q-methodology and a Pilot Randomized Controlled Tr NCT06261385 | The University of Hong Kong | N/A |
| Active Not Recruiting | PeRiopEratiVE SmokiNg CessaTion Trial NCT05102123 | Population Health Research Institute | Phase 3 |
| Recruiting | V+PSF-M for Tobacco Cessation in HIV Care in India NCT05786547 | University of Colorado, Denver | Phase 3 |
| Unknown | Mobile Phone-Based Smoking-Cessation Intervention for Chronic Patients NCT06187142 | Beijing Normal University | N/A |
| Terminated | Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT NCT06088862 | Rose Research Center, LLC | Phase 3 |
| Suspended | The Impact of Group Commitment Contracts on Smoking Cessation and Weight Loss NCT04224727 | National Bureau of Economic Research, Inc. | N/A |
| Completed | CAN-DOSE Study: Cessation With Augmented Nicotine for Dual Use Of Smoking and E-cigarettes NCT06087328 | Medical University of South Carolina | Phase 2 |
| Unknown | Small Talk Intervention With MI for Smoking Cessation NCT06148909 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Evaluating Smoking Cessation Interventions for PWH in South Africa NCT05413122 | Johns Hopkins University | Phase 2 / Phase 3 |
| Completed | Testing the Integrated mHealth App Intervention "SiS-H" NCT05886621 | Massachusetts General Hospital | N/A |
| Completed | Trial for Harm Reduction With Incentives & Vaping E-cigarettes NCT06111053 | Brown University | N/A |
| Withdrawn | The Effectiveness of Using E-Cigarettes for Smoking Cessation and Decreasing Risk of Diseases Among Heavy Smok NCT05639790 | Shenzhen Smoore Technology Limited | N/A |
| Recruiting | Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies NCT06471387 | University of Cyprus | — |
| Unknown | Effectiveness of the Evaluation and Communication of "Pulmonary Age" as Help for Smoking Cessation NCT04276116 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine NCT05994703 | Rose Research Center, LLC | Phase 2 |
| Recruiting | Personalized Tobacco Treatment in Primary Care (MOTIVATE) NCT05846841 | Washington University School of Medicine | N/A |
| Unknown | Mindfulness-based, Mobile Health (mHealth) Smoking Cessation Intervention in Vietnam NCT06228976 | Hanoi University of Public Health | N/A |
| Completed | Motivating Change in Aging Smokers NCT05194917 | University of Wisconsin, Madison | N/A |
| Recruiting | Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study NCT05460676 | Wake Forest University Health Sciences | N/A |
| Recruiting | Intervening to Promote Tobacco Cessation Following Psychiatric Hospitalization NCT05672914 | University of Texas at Austin | N/A |
| Completed | Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multipl NCT05981768 | Achieve Life Sciences | Phase 1 |
| Completed | Smoking Among Resident Physician and Their Role in Smoking Cessation Advice NCT07075263 | Mansoura University Hospital | — |
| Enrolling By Invitation | Botswana Smoking and Abstinence Reinforcement Trial NCT05694637 | University of Maryland, Baltimore | Phase 4 |
| Completed | BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study NCT05683821 | University of Wisconsin, Madison | N/A |
| Recruiting | Take A Break - Rural NCT05790486 | Wake Forest University Health Sciences | N/A |
| Recruiting | Stop Smoking in Spine Surgery NCT06361459 | Leiden University Medical Center | N/A |
| Unknown | Preloaded Combination Nicotine Replacement Therapy on Smoking Cessation of Adult Population in Kazakhstan NCT05484505 | Nazarbayev University | EARLY_Phase 1 |
| Withdrawn | TOBacco STOP in Chronic Obstructive Pulmonary Disease-Trial - Study Protocol NCT04088942 | Pradeesh Sivapalan | Phase 4 |
| Active Not Recruiting | Impact of Smoking Cessation Duration on Postoperative Complications in Lung Cancer Surgery NCT06663020 | Caner İşevi, MD | — |
| Unknown | Quit Smoking: Optimizing Health Promotion Strategy NCT06077058 | The University of Hong Kong | N/A |
| Unknown | Efficacy of a Designed Empathy Course NCT05864339 | The University of Hong Kong | N/A |
| Unknown | Intervention for Smoking Cessation in Pre-Surgical Patients. NCT05961813 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Unknown | Mobile EMA-based Peer Counselling for Youth Smokers NCT05732220 | The University of Hong Kong | N/A |
| Recruiting | Implementing an Intervention Named Volitional Help Sheets to Reduce Smoking Behaviour Among Young Adults in In NCT05629039 | University of Manchester | N/A |
| Recruiting | Bladder Cancer Screening Trial NCT05646485 | University of Texas Southwestern Medical Center | N/A |
| Active Not Recruiting | A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Di NCT05671380 | University of Minnesota | N/A |
| Completed | Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder NCT05796791 | Medical University of South Carolina | EARLY_Phase 1 |
| Withdrawn | Gut Microbiome and Weight Gain After Smoking Cessation NCT04618705 | Eran Elinav | N/A |
| Completed | Quit & Fit 2.0: Feasibility and Usability Testing NCT05878990 | Hackensack Meridian Health | N/A |
| Recruiting | Deep rTMS Modulating Insula Synaptic Density and Smoking Behavior in Schizophrenia NCT05724810 | Stony Brook University | N/A |
| Recruiting | Training Secondary School Students as Anti-smoke Ambassadors Using the Service-learning Model NCT05897346 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Overcoming Nicotine Dependence to Enable Quitting NCT05513872 | Rush University Medical Center | Phase 1 / Phase 2 |
| Completed | Mobile Chat Messaging for Smoking Relapse Prevention NCT05370352 | The University of Hong Kong | N/A |
| Completed | Message Testing in Aging African American Smokers NCT05819086 | University of Wisconsin, Madison | N/A |
| Completed | Community-Centered eHealth Smoking Cessation Intervention(CCeSCI) NCT05508672 | Duke Kunshan University | N/A |
| Recruiting | Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments NCT05764759 | Medical University of South Carolina | N/A |
| Completed | Development and Pilot Testing of the Sense2Quit App NCT05609032 | Columbia University | N/A |
| Unknown | Promoting Smoking Cessation in Campus NCT05777005 | Beijing Normal University | N/A |
| Completed | Efficacy and Neuroimaging Mechanisms of Smoking Cessation in China NCT05788068 | Sir Run Run Shaw Hospital | N/A |
| Recruiting | Effects of Smoking on Network Connectivity in Patients With Schizophrenia Symptoms in Scz Patients NCT07441928 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Improving Smoking Abstinence Outcomes in the African American Community Through Extended Treatment NCT05732272 | University of Kansas Medical Center | Phase 3 |
| Completed | Study Assessing Efficacy and Safety of NFL-101 on Reduction of Reinforcing Properties of Cigarettes (PRECESTO) NCT06091826 | NFL Biosciences SAS | Phase 2 |
| Completed | Impact of E-cigarette Nicotine Concentration on Compensation NCT05887947 | University of Kansas Medical Center | N/A |
| Completed | Exploratory Study of Switching From Combustible Cigarettes to the BIDI E-cigarette NCT05855343 | Rose Research Center, LLC | N/A |
| Completed | Cytisine for Smoking Cessation NCT05729243 | Centre for Addiction and Mental Health | Phase 4 |
| Completed | Smoking Cessation Outcomes and Effective Factors NCT05695742 | Saglik Bilimleri Universitesi | — |
| Recruiting | App for Pregnancy Smoking Cessation With Peer Support NCT05337722 | Michigan State University | N/A |
| Recruiting | Ending Tobacco Use Through Interactive Tailored Messaging for Cambodian People Living With HIV/AIDS NCT05746442 | H. Lee Moffitt Cancer Center and Research Institute | N/A |
| Unknown | Personalized Smoking Cessation Infographic in COPD NCT04119934 | Unity Health Toronto | — |
| Enrolling By Invitation | Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation NCT05627674 | Washington University School of Medicine | N/A |
| Completed | Latinos Kick Buts: Mobile Engagement and Cessation Support for Latinos Who Smoke NCT05722132 | University of Rochester | N/A |
| Recruiting | Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in St NCT05589220 | Poitiers University Hospital | N/A |
| Completed | Exenatide for Smoking Cessation and Prevention of Weight Gain NCT05610800 | The University of Texas Health Science Center, Houston | Phase 2 |
| Completed | Designing an Implementation Strategy for Lung Screening and Smoking Cessation Treatment in Community Health Ce NCT05447897 | University of Colorado, Denver | N/A |
| Completed | Feasibility of a Virtual Smoking Cessation Program NCT05594199 | University Health Network, Toronto | N/A |
| Recruiting | Smoking Cessation and Menstrual Cycle Phase NCT05515354 | Centre for Addiction and Mental Health | Phase 4 |
| Active Not Recruiting | Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS) NCT05645146 | H. Lee Moffitt Cancer Center and Research Institute | N/A |
| Active Not Recruiting | Influencing Factors and Trigger Mechanism of Relapse in Expectant Fathers Who Quit Smoking NCT05474651 | Sun Yat-sen University | — |
| Completed | SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups NCT05645354 | The University of Texas Health Science Center, Houston | N/A |
| Active Not Recruiting | Mobile Contingency Management for Smoking Cessation NCT04881630 | University of Oklahoma | N/A |
| Completed | Smoking Cessation Coaching in High-Risk Situations: A Virtual Reality Study NCT05654545 | Leiden University Medical Center | N/A |
| Completed | Varenicline for Treatment of E-cigarette Dependence NCT05541497 | Yale University | Phase 2 |
| Recruiting | Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study NCT05733767 | Baystate Medical Center | Phase 2 |
| Completed | Alaska Native Family-Based, Financial Incentives Intervention for Smoking Cessation NCT05413265 | Mayo Clinic | N/A |
| Enrolling By Invitation | The Next Step in Smoking Prevention: the Reduction of Tobacco Retail Outlets, a Comprehensive Policy Evaluatio NCT05554120 | Maastricht University Medical Center | — |
| Completed | Study to Evaluate Electrocardiographic Effects of Therapeutic & Supratherapeutic Doses of Cytisinicline in Hea NCT05566288 | Achieve Life Sciences | Phase 1 |
| Not Yet Recruiting | Group Education Helps Smoking Cessation and Hypertension Control NCT05530083 | Shanghai Jiao Tong University School of Medicine | N/A |
| Recruiting | Organization of Smoking Cessation in Pregnant Women With the Implementation of the 5A Strategy in New Aquitain NCT05355012 | University Hospital, Bordeaux | N/A |
| Completed | Testing a Novel Smartphone Application for Smoking Cessation With the Oklahoma Helpline NCT05539209 | University of Oklahoma | N/A |
| Terminated | Preoperative Smoking Cessation in Patients Undergoing Surgery NCT05192837 | Luzerner Kantonsspital | N/A |
| Recruiting | Enhancing Smoking Cessation Via Telehealth Options in Primary Care NCT05493254 | Medical University of South Carolina | N/A |
| Recruiting | Remote Smoking Cessation in Hospitalized Cardiac Patients NCT05738408 | University of Vermont Medical Center | N/A |
| Completed | Breathe 2 Project 3: Comprehensive Chronic Care NCT05382221 | University of Wisconsin, Madison | N/A |
| Completed | Testing the Efficacy of A Scalable, Telephone-Delivered, Guided Imagery Tobacco Cessation Intervention NCT05277831 | University of Arizona | N/A |
| Completed | Empowering LGBTQ+ Tobacco Cessation Pilot NCT05365633 | University of Oklahoma | N/A |
| Unknown | Towards Life-Long Healthy Lungs: A Multidisciplinary Follow-up Framework for Preterm Infants NCT05618769 | Franciscus Gasthuis | N/A |
| Completed | Message Testing in Older Adult Smokers NCT05471349 | University of Wisconsin, Madison | N/A |
| Unknown | Mixed and Match vs One-size-fits-all NCT05297370 | The Hong Kong Polytechnic University | N/A |
| Completed | An Integrated Smoking Cessation and Alcohol Intervention for Young People NCT05627765 | The Hong Kong Polytechnic University | N/A |
| Withdrawn | Smoking Cessation Study NCT04928781 | Dartmouth-Hitchcock Medical Center | N/A |
| Unknown | Post-discharge Cessation for Smoking Patients NCT05430789 | The University of Hong Kong | N/A |
| Unknown | Simple Physical Exercise With Instant Messaging Support for Smoking Via "Quit to Win" Contest 2022 (QTW2022) NCT05430451 | The University of Hong Kong | N/A |
| Completed | Alcohol Control in Smoking Cessation NCT05430529 | The University of Hong Kong | N/A |
| Completed | Randomized Pilot Study of a mHealth App for Ambivalent Smokers Living With HIV NCT05339659 | Kaiser Permanente | N/A |
| Completed | Effects of Aerobic Combined With Diaphragmatic Breathing Exercise in Smokers NCT05953987 | Chulalongkorn University | N/A |
| Recruiting | Circuitry-Guided Smoking Cessation in Schizophrenia (UH3) NCT05276050 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Latinos Kick Buts: Mobile Engagement and Cessation Support for Latino Smokers NCT05278481 | University of Rochester | N/A |
| Completed | Cytisine and E-cigarettes With Supportive Text-messaging for Smoking Cessation (Cess@Tion) NCT05311085 | University of Auckland, New Zealand | Phase 3 |
| Recruiting | Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondh NCT04783857 | University of Minnesota | Phase 4 |
| Active Not Recruiting | Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco NCT05290025 | Haukeland University Hospital | N/A |
| Active Not Recruiting | Factors Sustaining Tobacco Abstinence in Cancer Patients Treated With Radio-chemotherapy or Radiotherapy NCT06910566 | Centre Oscar Lambret | — |
| Recruiting | Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women NCT04985903 | Duke University | N/A |
| Completed | Use Determinants of Smoking Cessation App NCT05318651 | Paris Nanterre University | N/A |
| Completed | Effectiveness of Ecological Momentary Assessment Based Smoking Cessation Intervention NCT05212220 | The University of Hong Kong | N/A |
| Terminated | Cytisine Compared to Combination NRT in Relapsed Smokers NCT04286295 | Ottawa Heart Institute Research Corporation | N/A |
| Completed | Perioperative Smoking Cessation BUndle in a Tertiary Care Hospital - Can Turning Virtual Improve Outcomes? NCT04487548 | Fraser Health | N/A |
| Completed | Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV NCT05020899 | Boston Medical Center | N/A |
| Completed | Precision Pharmacotherapy Smoking Cessation Program NCT04897607 | Christiana Care Health Services | N/A |
| Completed | An Intervention to Promote Use of Smoking Cessation Resources Among Adults Using Community Food Pantries NCT05273450 | Case Western Reserve University | N/A |
| Completed | Increasing Digital Equity and Access Among Rural Patients (IDEA) Study NCT05209451 | Mayo Clinic | N/A |
| Completed | An Intervention to Promote Smoking Cessation Among Adults With Food Insecurity NCT05259852 | Case Western Reserve University | N/A |
| Completed | WeChat Quit Coach Pilot Study NCT05130788 | NYU Langone Health | N/A |
| Completed | Supporting Smoke-Free Policy Compliance in Public Housing NCT05016505 | Columbia University | N/A |
| Completed | Smoke-free Home Intervention in Permanent Supportive Housing NCT04855357 | University of California, San Francisco | N/A |
| Completed | A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers NCT05206370 | Achieve Life Sciences | Phase 3 |
| Recruiting | Prevention of Smoking Related Diseases NCT06451029 | Scientific Institute San Raffaele | — |
| Completed | Effectiveness of Transcranial Magnetic Stimulation (TMS) in Smoking Cessation, Combining Withdrawal Stimulatio NCT05152810 | Centre Hospitalier Universitaire Dijon | N/A |
| Completed | SmokefreeSGM, A Text-based Smoking Cessation Intervention for Sexual and Gender Minority Groups NCT05029362 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Cessation of Smoking Trial in the Emergency Department NCT04854616 | Norfolk and Norwich University Hospitals NHS Foundation Trust | N/A |
| Completed | Testing Integrative Smoking Cessation for HIV Patients NCT05030766 | University of Miami | Phase 4 |
| Recruiting | Biopsychosocial Predictors of Nicotine Relapse NCT06470321 | University of Cyprus | N/A |
| Completed | The Effect of Motivational Interviews Based on the Transtheoretic Model on Pregnant Women's Smoking Cessation NCT05173428 | Cumhuriyet University | N/A |
| Terminated | Remote Incentives for Smoking Cessation Among AN Pregnant Women NCT05019170 | University of Vermont | N/A |
| Active Not Recruiting | Automated Video-Assisted Smoking Treatment for People Living With HIV NCT05014282 | H. Lee Moffitt Cancer Center and Research Institute | N/A |
| Recruiting | Re-Connect Application for Smoking Cessation NCT05224154 | Rowan University | N/A |
| Suspended | Mobile App for Smoking Cessation and Mental Health NCT04887558 | University of Oklahoma | Phase 2 |
| Completed | The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette NCT05205811 | Rose Research Center, LLC | Phase 3 |
| Completed | Partnering With Food Bank to Provide Tobacco Treatment to Underserved Smokers NCT05004662 | H. Lee Moffitt Cancer Center and Research Institute | N/A |
| Recruiting | Wellness Intervention for Smoking and HIV NCT04725617 | University of Arizona | N/A |
| Completed | Contingency Management for Smoking Cessation NCT04982952 | University of California, San Francisco | N/A |
| Completed | Establishing the Effectiveness of Publicly Available Smoking Cessation Resource NCT05055778 | University of Virginia | N/A |
| Unknown | Nurse-led Smoking Cessation Program With Follow-up in Healthy Life Centres: a Randomized Clinical Trial NCT05049174 | Vestre Viken Hospital Trust | N/A |
| Withdrawn | Mobile Health Interventions for Medication Adherence Among PLWH NCT04191278 | Duke University | Phase 4 |
| Completed | QuitBet Phase II: A Digital Social Game That Pays You to Stop Smoking NCT05075213 | WayBetter, Inc. | N/A |
| Completed | A Multiple Health Behavior Change Intervention for Overweight and Obese Smokers NCT05136430 | Brown University | N/A |
| Completed | Stanford Tobacco Treatment Services - Virtual Reality Treatment for Smoking Cessation NCT05220254 | Stanford University | N/A |
| Completed | Preliminary Test of Reactive Carrot Incentives in a Practice Quit Environment With Contingency Management Ince NCT05072301 | Yale University | N/A |
| Active Not Recruiting | Construal Level as a Novel Pathway for Affect Regulation and Cancer Control NCT04620915 | University of Oregon | N/A |
| Completed | The Effect of the Education Program Based on the PRECEDE-PROCEED Model on the Smoking Behaviors of Nursing Stu NCT05314894 | Kirsehir Ahi Evran Universitesi | N/A |
| Completed | Efficacy of Centanafadine SR as a Potential Smoking Cessation Treatment NCT05066724 | Otsuka Pharmaceutical Development & Commercialization, Inc. | Phase 2 |
| Unknown | The Effect of Honey on Lessening the Withdrawal Symptoms NCT05264428 | Buddhist Tzu Chi General Hospital | N/A |
| Terminated | High Dose Bupropion for Smoking Cessation - Pilot Study NCT03326128 | University of Southern California | Phase 2 |
| Completed | QuitAid Pilot Feasibility Trial NCT05649241 | University of Virginia | N/A |
| Completed | Suvorexant to Reduce Symptoms of Nicotine Use NCT04234997 | The University of Texas Health Science Center, Houston | Phase 2 |
| Completed | CHIP and Residual Cardiovascular Event Tendency After Smoking Cessation NCT04987268 | Shenyang Northern Hospital | — |
| Completed | Helping Moms Quit Pilot Trial NCT05041413 | University of Kansas Medical Center | N/A |
| Completed | A First-in-Human Study of SBP-9330 in Healthy Subjects NCT04948827 | Camino Pharma, LLC | Phase 1 |
| Completed | eCEASE to Support Treatment for Parental Tobacco Use NCT04974736 | Massachusetts General Hospital | N/A |
| Completed | Combining Default Choices and a Decision Aid to Improve Tobacco Cessation NCT04868474 | Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland | N/A |
| Unknown | Mobile-based Positive Psychological Support for Smoking Cessation Via "Quit to Win" Contest 2021 (QTW 2021) NCT04909320 | The University of Hong Kong | N/A |
| Active Not Recruiting | Improving the Reach & Effectiveness of Smoking Cessation Services Targeted to Veterans Living With HIV NCT04505371 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Completed | Pilot Randomized Controlled Trial of a Smart Phone-Based Smoking Cessation Program NCT04955639 | Jennifer Marler, MD | N/A |
| Completed | Efficacy of Brief MI Delivered Via Mobile Instant Messaging to Help Unmotivated Smokers With Chronic Diseases NCT04890223 | The University of Hong Kong | N/A |
| Unknown | Development and Assessment of a Teacher-led Intervention in Preventing Tobacco Use Among the Youth in Ghana NCT04891939 | Ghana Health Services | N/A |
| Completed | CoQuit Study for Smoking Cessation NCT04893460 | Oregon Research Behavioral Intervention Strategies, Inc. | N/A |
| Unknown | Effectiveness of a Smoking Cessation Intervention in a Mental Health Day Hospital NCT05045326 | Hospital Clinic of Barcelona | N/A |
| Completed | TMS for Smoking Cessation in PLWHA Cessation in People Living With HIV/AIDS (PLWHA) NCT04936594 | Gopalkumar Rakesh | N/A |
| Unknown | Efficacy and Safety of Combination EMB-001 as a Potential Smoking Cessation Treatment NCT04868253 | Rose Research Center, LLC | Phase 2 / Phase 3 |
| Completed | Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening NCT04798664 | Abramson Cancer Center at Penn Medicine | N/A |
| Completed | Systematic Screening for COPD in Tabacology Consultation NCT04843605 | University Hospital, Brest | — |
| Active Not Recruiting | Telephone All Nations Breath of Life NCT04764175 | Lehigh University | N/A |
| Unknown | Effectiveness of Smoking Cessation Program in a Community Health System NCT05107687 | Virtua Health, Inc. | — |
| Completed | BAPS in Botswana: The Thotloetso Trial NCT04532970 | Abramson Cancer Center at Penn Medicine | N/A |
| Completed | Comparison of the Health Literacy of Our Patients Who Quit Smoking and Who Cannot Quit Smoking NCT04896554 | Bursa Yuksek Ihtisas Training and Research Hospital | N/A |
| Completed | AR Enhanced Pictorial Warnings on Smoking Cessation NCT04830072 | The University of Hong Kong | N/A |
| Unknown | Early Health Warning Intervention in Tobacco Control NCT04996329 | Peking University First Hospital | N/A |
| Active Not Recruiting | TirolGESUND: Baseline-controlled Comparison of the Effects of Fasting Dietary Intervention or Smoking Cessatio NCT05678426 | Universitaet Innsbruck | N/A |
| Unknown | Smoking Cessation Programme in Workplaces in Hong Kong (Phase Ⅴ) NCT04772521 | The University of Hong Kong | N/A |
| Completed | Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco NCT04737772 | Consumer Wellness Solutions | N/A |
| Unknown | Veteran Support for Smoking Cessation Pilot Project (VAntage Pilot) NCT04840108 | Minneapolis Veterans Affairs Medical Center | N/A |
| Completed | Study Assessing Efficacy and Safety of NFL-101 as a Tobacco Cessation Therapy NCT04571216 | NFL Biosciences SAS | Phase 2 |