| Not Yet Recruiting | Glucagon-like Peptide-1 Receptor Agonists for Endovascular Stroke Thrombectomy Ischemic Stroke | Phase 2 | 2026-06-30 |
| Not Yet Recruiting | Colchicine for the Reduction of Dependency and Vascular Events After an Acute Intracerebral Hemorrhage Colchicine, ICH - Intracerebral Hemorrhage, Stroke | Phase 3 | 2026-05-30 |
| Not Yet Recruiting | Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in IntraCranial Atherosclerot Ischemic Stroke, Intracranial Atherosclerosis | Phase 3 | 2026-05-30 |
| Not Yet Recruiting | Head of Bed After Ischemic Stroke Thrombectomy (HoBIT) Large Vessel Occlusion, Stroke, Ischemic Stroke | N/A | 2026-03-01 |
| Not Yet Recruiting | DOAC or VKA in Patients With AF and Stroke While on DOAC - a Pilot Trial Atrial Fibrillation (AF), Stroke (in Patients With Atrial Fibrillation) | EARLY_Phase 1 | 2025-09-03 |
| Recruiting | The Effect of Retrograde Autologous Priming on Transfusion Requirements After Cardiac Surgery Red Blood Cell Transfusion | N/A | 2024-12-04 |
| Recruiting | International CRDS Registry Calcium Release Deficiency Syndrome | — | 2024-11-21 |
| Recruiting | Pericardiotomy in Cardiac Surgery Atrial Fibrillation, Atrial Flutter, Cardiac Events | N/A | 2024-10-21 |
| Recruiting | DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery Atrial Fibrillation, Atrial Flutter | — | 2024-10-15 |
| Recruiting | Post Discharge After Surgery Virtual Care with Remote Automated Monitoring Technology-2 (PVC-RAM-2) Trial Surgery, Perioperative Complication | N/A | 2024-10-04 |
| Withdrawn | Single Dose Flecainide for Early Sinus Rhythm Conversion of Perioperative Atrial Fibrillation After Noncardiac Atrial Fibrillation, Surgery | Phase 4 | 2024-07-01 |
| Recruiting | Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients Pilot Trial Atrial Fibrillation New Onset | Phase 3 | 2024-06-13 |
| Active Not Recruiting | PeRiopEratiVE SmokiNg CessaTion Trial Smoking (Tobacco) Addiction, Smoking Cessation | Phase 3 | 2024-01-15 |
| Recruiting | Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivess Acute Myocardial Infarction, Coronary Artery Disease | N/A | 2023-06-22 |
| Recruiting | Frailty Assessments for Risk Assessment in Gynecologic Oncology Patients Gynecologic Cancer, Frailty, Oncology | — | 2023-06-15 |
| Recruiting | Surgical Ablation of AF Efficacy Trial Atrial Fibrillation, Heart Failure | N/A | 2023-06-01 |
| Recruiting | Reducing Mortality in Adults With Advanced HIV Disease (REVIVE) HIV Disease Progression | Phase 3 | 2023-05-08 |
| Recruiting | Evaluation of A Clinical Diagnostic Test for CRDS Calcium Release Deficiency Syndrome (CRDS) | N/A | 2023-02-02 |
| Recruiting | VIrtual Care To Improve Outcomes and RecoverY From Heart Failure Hospitalization Heart Failure | N/A | 2023-01-23 |
| Completed | Colchicine for the Prevention of Vascular Events After an Acute Intracerebral Hemorrhage Intracranial Hemorrhages | Phase 2 | 2022-08-04 |
| Withdrawn | Left Atrial Appendage Occlusion Study III Extended Follow Up Heart Failure, Left Atrial Appendage Occlusion | — | 2022-07-01 |
| Recruiting | Higher vs. Lower Dose Heparin for PCI Cardiovascular Diseases, Percutaneous Coronary Intervention | N/A | 2022-03-02 |
| Withdrawn | INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Superiori Rheumatic Heart Disease | Phase 3 | 2022-01-01 |
| Active Not Recruiting | Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology-3 Trial Surgery | N/A | 2021-12-28 |
| Active Not Recruiting | Living Green and Healthy for Teens Healthy Lifestyle, Adolescent Behavior | N/A | 2021-12-11 |
| Recruiting | HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial Hip Fractures, Myocardial Injury | N/A | 2021-11-22 |
| Recruiting | The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial Bleeding Post Cardiac Surgery, Indication for Anticoagulation | Phase 3 | 2021-07-18 |
| Recruiting | Safety of Continuing HER-2 Directed Therapy in Overt Left Ventricular Dysfunction Breast Cancer, Heart Failure | Phase 2 | 2021-07-01 |
| Recruiting | Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk Peripheral Arterial Disease, Atherosclerosis of Extremities, Inflammation | Phase 3 | 2021-05-06 |
| Recruiting | Bariatric Surgery for the Reduction of cArdioVascular Events Randomized Controlled Trial Cardiovascular Complication, Bariatric Surgery Candidate | N/A | 2020-11-02 |
| Completed | Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology (PVC-RAM) Trial Surgery, Perioperative Complication, COVID | N/A | 2020-04-23 |
| Completed | Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial Coronavirus, Severe Acute Respiratory Syndrome | Phase 3 | 2020-04-21 |
| Completed | Combination Antithrombotic Treatment for Prevention of Recurrent Ischemic Stroke in Intracranial Atherosclerot Ischemic Stroke, Intracranial Atherosclerotic Disease | Phase 3 | 2020-02-03 |
| Completed | Impact of Short-course Colchicine Versus Placebo After Pulmonary Vein Isolation (IMPROVE-PVI Pilot) Atrial Fibrillation, Recurrence | Phase 3 | 2020-01-14 |
| Completed | A Study on the Impact of Rabeprazole-induced Elevated Stomach pH on APO-Dabigatran Exposure in Healthy Volunte Atrial Fibrillation, Venous Thromboembolism | Phase 4 | 2020-01-03 |
| Active Not Recruiting | Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium Delirium, Post-cardiac Surgery | N/A | 2019-11-18 |
| Withdrawn | Diet and Exercise Frailty Intervention in Cardiac Device Patients Frailty, Cardiovascular Diseases | N/A | 2019-11-01 |
| Active Not Recruiting | EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF) Intracranial Hemorrhages, Atrial Fibrillation | Phase 4 | 2019-09-20 |
| Terminated | DEPOSITION - Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Su Bleeding, Surgical Blood Loss, Seizures | Phase 3 | 2019-09-17 |
| Recruiting | Low INR to Minimize Bleeding With Mechanical Valves Trial Bleeding Post-mechanical Valve Replacement, Thromboembolism Post-mechanical Valve Replacement | Phase 3 | 2019-09-05 |
| Recruiting | Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transi Stroke, Atrial Fibrillation | Phase 4 | 2019-06-14 |
| Completed | Ross for Valve Replacement in Adults - Registry Aortic Valve Disease | — | 2019-06-03 |
| Completed | High Sensitivity Estimate of the Incidence of Atrial Fibrillation Occurring Transiently With Stress (AFOTS Inc Atrial Fibrillation New Onset | — | 2019-06-01 |
| Completed | DIalysis Symptom COntrol-Restless Legs Syndrome Trial End Stage Renal Disease, Restless Legs Syndrome | Phase 3 | 2019-05-01 |
| Completed | Ross for Valve Replacement in AduLts Trial Aortic Valve Disease | N/A | 2019-04-29 |
| Completed | Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IDegLira Type 2 Diabetes Mellitus | Phase 3 | 2019-04-23 |
| Completed | Effects of Acute, Rapid Lowering of LDL Cholesterol With Alirocumab in Patients With STEMI Undergoing Primary ST Elevation Myocardial Infarction, Acute Coronary Syndrome, Hypercholesterolemia | Phase 2 | 2019-03-11 |
| Completed | A Pan-Canadian, Retrospective Evaluation of MitraClip Safety and Efficacy Mitral Regurgitation | — | 2019-01-01 |
| Completed | Small-Volume Tubes to Reduce Anemia and Transfusion Blood Loss Anemia | N/A | 2019-01-01 |
| Completed | Verification of The Cloud DX Vitaliti™ Continuous Vital Sign Monitor (CVSM): Non-invasive Blood Pressure Compo Blood Pressure | N/A | 2018-08-09 |
| Completed | PeriOperative ISchemic Evaluation-3 Trial Perioperative Bleeding, Venous Thrombosis, Arterial Thrombosis | Phase 3 | 2018-06-27 |
| Completed | Routine Ultrasound Guidance for Vascular Access for Cardiac Procedures Myocardial Infarction, Coronary Artery Disease, Myocardial Ischemia | N/A | 2018-06-20 |
| Unknown | Remote ECG Monitoring of TAVI Patients Cardiac Valve Disease, Aortic Valve Stenosis | N/A | 2018-06-20 |
| Completed | Adjunctive, Low-dose tPA in Primary PCI for STEMI Myocardial Infarction, Percutaneous Coronary Intervention | Phase 3 | 2018-04-01 |
| Completed | Prevalence of Subclinical Atrial Fibrillation in Heart Failure Patients and Its Relationship With Hospital Rea Heart Failure, Atrial Fibrillation | — | 2018-03-24 |
| Completed | Prevention of Infections in Cardiac Surgery (PICS) Prevena Study Surgical Site Infections | Phase 4 | 2018-03-05 |
| Completed | Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (CO Atrial Fibrillation, Atrial Flutter, Myocardial Injury After Non-Cardiac Surgery | Phase 3 | 2018-02-14 |
| Completed | Colchicine and Spironolactone in Patients with MI / SYNERGY Stent Registry ST Elevation Myocardial Infarction, Non ST Elevation Myocardial Infarction | Phase 3 | 2018-02-01 |
| Completed | Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery Bleeding, Surgical Blood Loss | Phase 4 | 2017-12-21 |
| Completed | Small-Volume Tubes to Reduce Anemia and Transfusion (STRATUS) Blood Loss Anemia | — | 2017-11-01 |
| Completed | Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease Endstage Renal Disease | Phase 3 | 2017-07-07 |
| Completed | Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixi Type 2 Diabetes Mellitus | Phase 3 | 2017-06-27 |
| Terminated | Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial Pain, Postoperative | Phase 3 | 2017-05-04 |
| Completed | NOACs for Stroke Prevention in Patients With Atrial Fibrillation and Previous ICH Atrial Fibrillation, Intracerebral Hemorrhage | Phase 2 | 2017-04-26 |
| Completed | Detection and Neurological Impact of Cerebrovascular Events in Cardiac Surgery Patients Silent Stroke, Cognitive Decline | — | 2017-03-27 |
| Completed | Atrial Fibrillation Occurring Transiently With Stress (AFOTS) Atrial Fibrillation New Onset | — | 2017-03-01 |
| Completed | Avoid Transvenous Leads in Appropriate Subjects Ventricular Arrhythmia | N/A | 2017-02-22 |
| Completed | Young ESUS Patient Registry Embolic Stroke of Undetermined Source | — | 2017-02-15 |
| Completed | Safety of Continuing CHemotherapy in Overt Left Ventricular Dysfunction Using Antibodies to HER-2 Heart Failure, Breast Cancer | Phase 1 | 2016-11-01 |
| Withdrawn | The Strategy to Prevent Hemorrhage Associated With Anticoagulation in Renal Disease Management (STOP HARM) Tri Chronic Kidney Disease, Acute Bleeding, Cerebrovascular Stroke | Phase 4 | 2016-09-01 |
| Completed | INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Infer Rheumatic Heart Disease | Phase 3 | 2016-08-22 |
| Completed | Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita) Type 2 Diabetes Mellitus | Phase 3 | 2016-07-09 |
| Terminated | AMIOdarone vs. Catheter Ablation for Prevention of Recurrent Symptomatic Atrial Fibrillation Atrial Fibrillation | Phase 4 | 2016-01-01 |
| Completed | Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Forxiga Type 2 Diabetes Mellitus | Phase 4 | 2015-12-01 |
| Completed | Thrombectomy in ST Elevation Myocardial Infarction, an Individual Patient Meta-analysis Myocardial Infarction, Acute Coronary Syndromes | — | 2015-09-01 |
| Completed | Study of the Risk Factors and Outcomes After Gastrointestinal Bleeding Gastrointestinal Hemorrhage, Cardiovascular Diseases | — | 2015-09-01 |
| Completed | Tetralogy of Fallot for Life Tetralogy of Fallot, Congenital Heart Disease, Congenital Heart Defect | — | 2015-06-08 |
| Completed | Canadian Community Utilization of Stroke Prevention Study - Emergency Department Atrial Fibrillation, Stroke | N/A | 2015-06-01 |
| Completed | Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillati Atrial Fibrillation, Stroke | Phase 4 | 2015-05-01 |
| Completed | Home-Based Screening for Early Detection of Atrial Fibrillation in Primary Care Patients Aged 75 Years and Old Atrial Fibrillation, Hypertension | N/A | 2015-04-01 |
| Completed | Program for the Identification of "Actionable" Atrial Fibrillation in the Family Practice Setting Atrial Fibrillation | N/A | 2015-04-01 |
| Completed | Patient-centered Care Transitions in Heart Failure: A Pragmatic Cluster Randomized Trial Heart Failure | N/A | 2015-03-01 |
| Completed | Colchicine in Atrial Fibrillation to Prevent Stroke Atrial Fibrillation, Stroke | Phase 3 | 2014-11-01 |
| Completed | Colchicine For Prevention of Perioperative Atrial Fibrillation in Patients Undergoing Thoracic Surgery Pilot S Atrial Fibrillation, Thoracic Surgery | Phase 3 | 2014-04-01 |
| Completed | Prevalence of Sub-Clinical Atrial Fibrillation in Elderly Patients With Hypertension, Detected Using an Extern Elderly, Hypertension, Risk Factors for Atrial Fibrillation | — | 2014-01-01 |
| Completed | Hip Fracture Impact on Vascular Events In Noncardiac Surgery patIents: a cOhort evaluatioN (Hip VISION): Pilot Hip Fractures | — | 2013-12-01 |
| Completed | Vascular Events In Surgery patIents cOhort evaluatioN - Cardiac Surgery Vascular Death, Myocardial Infarction, Stroke | — | 2013-05-01 |
| Completed | Complete vs Culprit-only Revascularization to Treat Multi-vessel Disease After Early PCI for STEMI Acute Myocardial Infarction, Coronary Artery Disease | N/A | 2013-02-01 |
| Completed | Management of Myocardial Injury After Noncardiac Surgery Trial Myocardial Injury After Noncardiac Surgery (MINS) | Phase 3 | 2013-01-01 |
| Completed | Prevalence of Sub-Clinical Atrial Fibrillation Using an Implantable Cardiac Monitor Atrial Fibrillation | — | 2012-12-01 |
| Completed | Prevention of Arrhythmia Device Infection Trial (PADIT) Arrhythmia | Phase 4 | 2012-12-01 |
| Completed | Left Atrial Appendage Occlusion Study III Cardiac Surgery With Cardiopulmonary Bypass, Atrial Fibrillation | N/A | 2012-07-01 |
| Completed | The International Polycap Study 3 (TIPS-3) Cardiovascular Disease, Fractures, Cancers | Phase 3 | 2012-06-01 |
| Completed | HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial Hip Fractures | N/A | 2011-07-01 |
| Completed | Prevention of Arrhythmia Device Infection Trial (PADIT) Arrhythmia | Phase 4 | 2011-05-01 |
| Completed | Clopidogrel and Aspirin Interaction Study-2 Drug Action Increased | Phase 4 | 2011-05-01 |
| Terminated | Transcutaneous Oximetry, Transcutaneous Carbon Dioxide and Supplemental Oxygen Therapy in Lower Limb Amputatio Amputation Wound | — | 2011-04-01 |
| Completed | Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT Pilot Trial) Type 2 Diabetes Mellitus | Phase 4 | 2011-01-01 |
| Terminated | Catheter Ablation Versus Amiodarone for Shock Prophylaxis in Defibrillator Patients With Ventricular Tachycard Defibrillators, Implantable, Tachycardia, Ventricular | Phase 3 | 2010-08-01 |
| Completed | A Trial of Routine Aspiration Thrombectomy With Percutaneous Coronary Intervention (PCI) Versus PCI Alone in P Acute Coronary Syndrome, ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention | N/A | 2010-08-01 |
| Completed | Clopidogrel/Aspirin Interaction Study Coronary Artery Disease | Phase 4 | 2010-04-01 |
| Completed | Prevention of Arrhythmia Device Infection Trial (PADIT Pilot) Arrythmias | Phase 3 | 2009-12-01 |
| Completed | Randomized Comparison of Warfarin Dosing Quality Between the Hamilton Nomogram and a Commercial Computer Syste Patients at Risk for Thrombosis | Phase 3 | 2009-11-01 |
| Completed | Simple Warfarin Dosing Algorithm Study Warfarin Dosing | N/A | 2009-10-01 |
| Completed | Left Atrial Appendage Occlusion Study II Atrial Fibrillation, Stroke | Phase 3 | 2009-08-01 |
| Completed | REsearching Coronary REduction by Appropriately Targeting Euglycemia (RECREATE Pilot Study) Hyperglycemia, Cardiovascular Diseases, Myocardial Infarction | Phase 3 | 2008-04-01 |
| Completed | Coronary Artery Bypass Surgery (CABG) Off or On Pump Revascularization Study the Efficacy and Safety of Off-pump CABG | Phase 3 | 2007-10-01 |
| Unknown | Steroids In caRdiac Surgery Trial (SIRS Trial) Cardiac Surgical Procedures, Cardiopulmonary Bypass, Systemic Inflammatory Response Syndrome | Phase 4 | 2007-06-01 |
| Completed | Heart Outcomes Prevention Evaluation-3 Cardiovascular Disease, Stroke | Phase 4 | 2007-05-01 |
| Completed | First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT St Atrial Fibrillation | Phase 3 | 2006-08-01 |
| Completed | A Trial of Trans-radial Versus Trans-femoral Percutaneous Coronary Intervention (PCI) Access Site Approach in Acute Coronary Syndrome, Percutaneous Coronary Intervention | Phase 3 | 2006-06-01 |
| Completed | Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes Unstable Angina, Myocardial Infarction | N/A | 2005-05-01 |
| Completed | BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Diseas Chagas Disease, Trypanosomiasis, Heart Disease | Phase 3 | 2004-11-01 |
| Completed | Study of Health Assessment and Risk Evaluation in Aboriginal Peoples Action Toward Obesity Prevention (SHARE-A Obesity | N/A | 2004-05-01 |
| Recruiting | Prospective Urban Rural Epidemiology Study Cardiovascular Diseases, Risk Factor, Cardiovascular, Health Behavior | — | 2002-01-01 |