Clinical Trials Directory

Trials / Completed

CompletedNCT05159219

Colchicine for the Prevention of Vascular Events After an Acute Intracerebral Hemorrhage

A Vanguard, Double-blind, Randomized, Placebo-controlled, Phase 2 Pilot Study to Investigate Prevention of Cardiovascular Events with Oral Colchicine 0.5mg Once Daily Compared with Placebo in Participants with Spontaneous ICH and Established, or Risk Factors For, Atherosclerosis

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
100 (actual)
Sponsor
Population Health Research Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The overall goal is to establish the safety and efficacy of colchicine in ICH patients for the prevention of major cardiovascular events and brain injury. Colchicine for the prevention of vascular events after an acute intracerebral hemorrhage (CoVasc-ICH) is a vanguard pilot trial designed to obtain the factual feasibility prerequisites essential for the planning, design, funding and execution of a subsequent phase III trial.

Conditions

Interventions

TypeNameDescription
DRUGColchicine PillAnti-inflammatory
OTHERPlaceboInert ingredients

Timeline

Start date
2022-08-04
Primary completion
2024-12-03
Completion
2024-12-03
First posted
2021-12-16
Last updated
2025-01-16

Locations

11 sites across 1 country: Canada

Source: ClinicalTrials.gov record NCT05159219. Inclusion in this directory is not an endorsement.