NCT01181674

Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT Pilot Trial)

Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT): A Randomized Controlled Pilot Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 83 (actual)
• Sponsor: Population Health Research Institute · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this pilot trial is to determine whether an intensive treatment with insulin glargine, metformin, acarbose and lifestyle can normalize blood glucose levels in patients with recently diagnosed type 2 diabetes mellitus when compared to standard diabetes care.

Detailed description

This is a pilot trial of 125 patients allocated to either usual care (1/3), 2 months or 4 months of intensive lifestyle and pharmacotherapy followed by cessation of all drug therapy.

Conditions

• Type 2 Diabetes Mellitus

Interventions

Type	Name	Description
DRUG	insulin glargine	sc injection
DRUG	metformin	oral administration
DRUG	acarbose	oral administration
BEHAVIORAL	lifestyle therapy	diet and exercise
DRUG	insulin glargine	sc injection
DRUG	metformin	oral administration
DRUG	acarbose	oral administration
BEHAVIORAL	lifestyle therapy	diet and exercise
OTHER	Standard glycemic care	as informed by the current clinical practice guidelines

Timeline

• Start date: 2011-01-01
• Primary completion: 2015-02-01
• Completion: 2015-09-01
• First posted: 2010-08-13
• Last updated: 2020-05-21
• Results posted: 2020-05-21

Locations

1 site across 1 country: Canada