NCT02552407

Thrombectomy in ST Elevation Myocardial Infarction, an Individual Patient Meta-analysis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 18,000 (estimated)
• Sponsor: Population Health Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

During primary percutaneous coronary intervention, distal embolization of thrombus and impaired microvascular perfusion has been associated with an increased mortality. Thrombectomy devices during primary percutaneous coronary intervention may prevent distal embolization by reducing thrombus burden and thus improve microvascular perfusion and reduce mortality.

Detailed description

An individual patient meta-analysis of large randomized controlled trials comparing manual thrombectomy versus percutaneous coronary intervention alone in patients with ST elevation myocardial infarction will provide significantly more power to detect differences in mortality as well as important but rare events such as stroke and to assess benefits in pre-defined subgroups.

Conditions

• Myocardial Infarction
• Acute Coronary Syndromes

Interventions

Type	Name	Description
DEVICE	Manual Aspiration Thrombectomy	Thrombus aspiration

Timeline

• Start date: 2015-09-01
• Primary completion: 2016-11-01
• Completion: 2016-11-01
• First posted: 2015-09-17
• Last updated: 2017-10-25