| Recruiting | Trauma-Informed Care for Smoking Cessation for Pregnancy NCT07129590 | University of California, San Francisco | N/A |
| Recruiting | Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness NCT07148232 | University of California, San Francisco | Phase 4 |
| Recruiting | CONNECT Cancer Survivors With Tobacco Treatment NCT07020273 | Washington University School of Medicine | N/A |
| Recruiting | Cannabis-Tobacco Co-Use Treatment Study NCT06883162 | Medical University of South Carolina | Phase 3 |
| Enrolling By Invitation | An Evaluation of the Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping Intervention NCT06483412 | Stanford University | N/A |
| Recruiting | Reach Through Equitable Implementation in Utah NCT06881069 | University of Utah | N/A |
| Active Not Recruiting | Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion) NCT04827420 | University of Illinois at Chicago | N/A |
| Active Not Recruiting | Cessation Clinical Trial NCT06806098 | Truth Initiative | N/A |
| Active Not Recruiting | Feasibility of Delivering VergeRx at FQHCs NCT06161675 | University of Virginia | N/A |
| Withdrawn | Emergency Department Management of Tobacco Use Disorder NCT06350175 | West Virginia University | Phase 4 |
| Recruiting | Tabacco Cessation in Hospital Services NCT07031024 | Centre Hospitalier Universitaire de Nice | — |
| Active Not Recruiting | Impact of Multi-Component Interventions on High-Risk COPD Smokers NCT06458205 | Peking Union Medical College | N/A |
| Completed | Tobacco Cessation at FDNY NCT05997225 | Albert Einstein College of Medicine | Phase 4 |
| Recruiting | Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation NCT06438549 | Loma Linda University | N/A |
| Enrolling By Invitation | Evaluation of the Effectiveness of 5A-5R Counselling Services for Tobacco Cessation NCT06501209 | BRAC University | N/A |
| Recruiting | Development of a Smoking Cessation Video Series NCT06443294 | Wayne State University | N/A |
| Recruiting | Smoking Cessation Program in the Construction Sector NCT06098144 | University of Miami | Phase 4 |
| Completed | Implementation Science to Reduce the Disparity in Tobacco Treatment Among Individuals With Serious Mental Illn NCT05952401 | Washington University School of Medicine | N/A |
| Completed | Evaluating the Impact of a Photoaging App Versus School-Based Educational Intervention on Adolescents' Knowled NCT06483763 | Sultan Qaboos University | N/A |
| Completed | Tobacco Cessation Care for Cancer Patients by Automated Interactive Outreach NCT05829824 | University of California, San Francisco | N/A |
| Terminated | Smoking Cessation Support for Patients With Rheumatologic Diseases Via WhatsApp NCT06219551 | Recep Tayyip Erdogan University Training and Research Hospital | N/A |
| Completed | Adapting and Evaluating a Brief Advice Tobacco Intervention in High-Reach, Low-Resource Settings in India NCT05234983 | Harvard School of Public Health (HSPH) | N/A |
| Unknown | Feasibility, Adoption and Efficacy of A Virtual Reality Smoking Cessation Program for Patients Undergoing Lung NCT06021652 | Cedars-Sinai Medical Center | N/A |
| Enrolling By Invitation | Enhancing Equity in Smoke-free Housing NCT06042361 | Harvard School of Public Health (HSPH) | N/A |
| Completed | Feasibility of a Diabetes Specialist Nurse-led Smoking Cessation Intervention NCT05920096 | University of Malta | N/A |
| Active Not Recruiting | Comparing Smartphone to In-person Training to Scale Up a Tobacco Control Program for Teachers in India NCT05500235 | Harvard School of Public Health (HSPH) | N/A |
| Completed | Integrating Tobacco Use Cessation Into HIV Care and Treatment in Kisumu County, Kenya NCT05351606 | University of California, San Francisco | Phase 4 |
| Recruiting | Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary NCT05415761 | University of Florida | N/A |
| Recruiting | Cognitive Behavioral Treatment with Activity Trackers for Smoking Cessation NCT06629467 | University of Oviedo | N/A |
| Active Not Recruiting | A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Di NCT05671380 | University of Minnesota | N/A |
| Recruiting | Comprehensive Tobacco Cessation for Cancer Patients and Survivors NCT05805722 | Virginia Commonwealth University | N/A |
| Unknown | Enhanced Multicomponent Proactive Navigator-Assisted Cessation of Tobacco Use in Low-Income Patients NCT05750537 | Family Health Centers of San Diego | N/A |
| Unknown | TinCat LGBTQ+ Smoking Cessation Via Asynchronous Telehealth NCT05499364 | University of Texas at Austin | N/A |
| Enrolling By Invitation | Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation NCT05627674 | Washington University School of Medicine | N/A |
| Completed | Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients NCT05021185 | University of California, San Francisco | N/A |
| Recruiting | Oral Cannabidiol for Tobacco Cessation NCT05445804 | Johns Hopkins University | Phase 1 |
| Active Not Recruiting | Development of UP2UTobacco for High School Youth NCT05396911 | University of Virginia | N/A |
| Completed | Interest of an Auriculotherapy Session in Smoking Cessation NCT04880330 | Hopital Foch | N/A |
| Completed | Study of the Effectiveness of a Virtual Reality Treatment in the Management of Smoking Cessation NCT04610931 | University Hospital, Clermont-Ferrand | N/A |
| Completed | Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempt NCT04994444 | Brown University | Phase 2 / Phase 3 |
| Completed | Tobacco Cessation Tailored to Patients Living With HIV (PLWH) in Brazil NCT05560243 | University of Alabama at Birmingham | N/A |
| Unknown | Attentional Bias Modification Training for E-cigarette Users NCT05112562 | University of Wisconsin, Milwaukee | N/A |
| Completed | Implementation of Genomics in Substance Use Disorder Treatment NCT04768114 | Washington University School of Medicine | N/A |
| Completed | Targeting Mailed Nicotine Patch Distribution Interventions to Rural Regions of Canada NCT04606797 | Centre for Addiction and Mental Health | Phase 4 |
| Completed | Offering Nicotine Patches to All Households in a Municipality With High Smoking Rates NCT04534231 | Centre for Addiction and Mental Health | — |
| Completed | Enhancing Electronic Health Systems to Decrease the Burden of Colon Cancer, Lung Cancer, Obesity, Vaccine-Prev NCT04540081 | University of California, Davis | N/A |
| Completed | A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV NCT04490057 | Yale University | Phase 4 |
| Completed | Interventions to Help More Low-income Smokers Quit NCT04311983 | Washington University School of Medicine | N/A |
| Completed | Engagement With an Adaptive Mobile Health Smoking Cessation Intervention NCT04020718 | Massachusetts General Hospital | Phase 4 |
| Enrolling By Invitation | Financial Incentives for Smoking Treatment II NCT03979885 | University of California, Los Angeles | N/A |
| Unknown | Screening While You Wait 2: Alcohol and Tobacco Use NCT04594304 | Women's College Hospital | N/A |
| Completed | Connecting Alaska Native People to Quit Smoking NCT03645941 | Mayo Clinic | N/A |
| Withdrawn | Inpatient Smoking Cessation Pilot Program NCT05060965 | Johns Hopkins University | EARLY_Phase 1 |
| Completed | Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes NCT04188197 | Rose Research Center, LLC | N/A |
| Completed | Interactive Communication Technologies and Nicotine Replacement Therapy Sampling for Smokers NCT04001972 | The University of Hong Kong | N/A |
| Completed | Evaluating the Feasibility and Efficacy of a Real-time Smoking Intervention Using Wearable Technology NCT04172623 | Yale University | N/A |
| Completed | Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI) NCT03873337 | Rutgers, The State University of New Jersey | N/A |
| Completed | Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers NCT03927976 | Case Comprehensive Cancer Center | N/A |
| Completed | Short Messaging Service Program to Help Quit Smoking During Perioperative Period. NCT03839043 | Mayo Clinic | N/A |
| Withdrawn | Varenicline for Smoking Cessation in Hospitalized Patients With Psychiatric Disorders NCT03809897 | Hospital Universitari Vall d'Hebron Research Institute | Phase 4 |
| Completed | mHealth Messaging to Motivate Quitline Use Quitting NCT03567993 | University of Massachusetts, Worcester | N/A |
| Completed | An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers NCT03553992 | University of California, San Francisco | N/A |
| Completed | Brief Advice, Nicotine Replacement Therapy Sampling and Active Referral (BANSAR) for Smoking Fathers NCT03671707 | The University of Hong Kong | N/A |
| Completed | Effectiveness of a Chat Bot for Smoking Cessation: a Pragmatic Trial in Primary Care. NCT03445507 | Gerencia de Atención Primaria, Madrid | N/A |
| Completed | Optimizing the Tobacco Cessation Clinical Decision Support Tool. NCT03714191 | NYU Langone Health | — |
| Completed | Improving Quitline Support Study NCT03538938 | University of Wisconsin, Madison | Phase 4 |
| Completed | mHealth Intervention to Prevent Postpartum Smoking Relapse NCT04207827 | Babes-Bolyai University | N/A |
| Completed | Disseminating an Evidence-based Tobacco Control Intervention for School Teachers in India NCT05346991 | Glorian Sorensen | N/A |
| Completed | PRecision Interventions for SMoking in the SCCS NCT03521141 | Vanderbilt University Medical Center | Phase 2 / Phase 3 |
| Completed | Project Q Pilot: Smoking Cessation for Light Smokers NCT03416621 | Duke University | Phase 3 |
| Completed | A Facebook Intervention for Young Sexual and Gender Minority Smokers NCT03259360 | University of California, San Francisco | N/A |
| Completed | Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women NCT03209557 | University of Pennsylvania | N/A |
| Completed | Helping Poor Smokers Quit NCT03194958 | Washington University School of Medicine | N/A |
| Completed | Text Messaging and Telephone Counseling for Supporting Post-discharge Quit Attempts NCT03237949 | Federal University of Juiz de Fora | N/A |
| Completed | Enhancing Quitline Services for African American Smokers NCT03064971 | Case Comprehensive Cancer Center | N/A |
| Completed | IMPACT OF PAMPHLET ON THE KNOWLEDGE OF HEALTH EFFECT OF SMOKING NCT03316495 | University of Benin | N/A |
| Completed | EHR-Based and Fax-Based Referral to a Tobacco Quitline: A Comparative Study NCT02735382 | University of Wisconsin, Madison | N/A |
| Completed | Changing the Default for Tobacco Treatment NCT02721082 | University of Kansas Medical Center | Phase 4 |
| Completed | Metabolism-informed Care for Smoking Cessation NCT03227679 | Vanderbilt University Medical Center | N/A |
| Active Not Recruiting | Reward Sensitivity and Pharmacotherapy for Smoking Cessation NCT02162849 | M.D. Anderson Cancer Center | Phase 4 |
| Completed | American Indians STOp Smoking by Mobile Phone NCT03168451 | Washington State University | N/A |
| Completed | Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers NCT02596711 | M.D. Anderson Cancer Center | Phase 1 / Phase 2 |
| Completed | Implementing Tobacco Use Guidelines in Community Health Centers in Vietnam Public Health System NCT02564653 | NYU Langone Health | N/A |
| Completed | Text Messaging for Supporting Quit Attempts NCT02571244 | Federal University of Juiz de Fora | N/A |
| Unknown | Evaluation of Efficacy of Different Methods of Tobacco Cessation Interventions Among BEST Employees in Mumbai NCT02397369 | Tata Memorial Hospital | N/A |
| Completed | PCORI-CER-1306-03385 Informed Decisions About Lung Cancer Screening NCT02286713 | M.D. Anderson Cancer Center | N/A |
| Terminated | Mobile Media-Rich Interactive Guideline System (MMRIGS) Pilot Study NCT02302859 | M.D. Anderson Cancer Center | N/A |
| Unknown | Optimizing Technology-Delivered Interventions for Smoking in Pregnancy: The Mommy Check-Up Study. NCT02340624 | Wayne State University | N/A |
| Completed | Interventions to Help Smoking Parents of Inpatients Reduce Exposure (INSPIRE) NCT02281864 | University of Colorado, Denver | N/A |
| Completed | Progesterone & Postpartum Relapse to Smoking NCT01798394 | University of Minnesota | N/A |
| Completed | The PROMPT Pilot Study NCT03626064 | Ottawa Hospital Research Institute | N/A |
| Withdrawn | An Evidence Based Smoking Cessation Program for Persons Living With HIV/AIDS (Project Legacy) NCT02029612 | M.D. Anderson Cancer Center | N/A |
| Completed | A Family-Based Approach To Reduce Smoking in Vietnamese Men NCT02007707 | University of California, San Francisco | N/A |
| Completed | Quit IT: Preliminary Testing of a Web-based, 3D Coping Skills Game to Increase Quitting Self-Efficacy for Main NCT02099097 | Memorial Sloan Kettering Cancer Center | N/A |
| Withdrawn | Implementing Tobacco Use Guidelines in Community Health Centers in Vietnam NCT01967654 | NYU Langone Health | N/A |
| Completed | Middle and High School Students' Reactions to a Health Interactive Website: ASPIRE Reactions NCT02469779 | M.D. Anderson Cancer Center | N/A |
| Completed | Families Reduce Exposure to Smoke at Home NCT02557919 | Harvard School of Public Health (HSPH) | N/A |
| Completed | Implementation of HIT-Enhanced Tobacco Treatment for Hospitalized Smokers NCT01691105 | Yale University | N/A |
| Completed | Project Impact: A Culturally-Tailored Adherence Intervention for Latino Smokers NCT01811628 | M.D. Anderson Cancer Center | — |
| Completed | Smoking Cessation for Young Adult Pacific Islanders: Motivating Pacifika Against Cigarettes and Tobacco NCT03238456 | Claremont Graduate University | N/A |
| Completed | OCAST Cessation Study NCT01921439 | University of Oklahoma | N/A |
| Active Not Recruiting | Ask Advise Connect (AAC) Harris Heath CPRIT NCT01788787 | M.D. Anderson Cancer Center | — |
| Completed | Improving Adherence to Smoking Cessation Medication Among PLWHA NCT01898195 | NYU Langone Health | N/A |
| Completed | Functional Assessment Screening Patient Reported Information NCT01669564 | University of Pittsburgh | N/A |
| Completed | Innovative Web-Based Intervention for Smoking Cessation Among College Students NCT01982825 | Emory University | Phase 1 |
| Completed | Exploring Occupancy of Dopamine D3 Receptor by Buspirone in Humans Using PET NCT01699828 | Centre for Addiction and Mental Health | Phase 1 / Phase 2 |
| Completed | A Multi-Media Approach to Partner Support in Smokeless Tobacco Cessation (UCare-ChewFree) NCT01885221 | Oregon Research Institute | N/A |
| Completed | Gender-Relevant Tobacco Cessation Among Women in Brazil NCT03845413 | University of Alabama at Birmingham | N/A |
| Terminated | Brief Intervention Study for Quitting Smoking NCT01589211 | Heidelberg University | N/A |
| Completed | Telephone Counseling for Tobacco Cessation NCT01489579 | Kaiser Permanente | N/A |
| Completed | Emergency Department Smoking Cessation Study NCT01454375 | University of British Columbia | N/A |
| Completed | Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV NCT01570595 | Georgetown University | Phase 1 / Phase 2 |
| Completed | Quit IT: Development of a Web-based, 3D Coping Skills Game to Increase Self-Efficacy for Maintaining Smoking A NCT01915836 | Memorial Sloan Kettering Cancer Center | N/A |
| Completed | Offering Proactive Tobacco Treatment NCT01123967 | University of Minnesota | N/A |
| Completed | Treating Low-Income Smokers in the Hospital Emergency Department NCT01328431 | Yale University | N/A |
| Completed | Smoking Cessation Invention in the Emergency Department (ED) NCT01173653 | Vanderbilt University | N/A |
| Completed | Community-Partnered Dominican Republic Tobacco Control NCT01228916 | University of Rochester | N/A |
| Completed | Mumbai Worksite Tobacco Control Study NCT01841879 | Harvard School of Public Health (HSPH) | N/A |
| Completed | Quit and Win Contests to Improve Smoking Cessation Among College Students NCT01096108 | University of Minnesota | N/A |
| Completed | Tobacco Tactics Website for Operating Engineers NCT01124110 | University of Michigan | Phase 3 |
| Completed | Tobacco Cessation for Veterans With Post Traumatic Stress Disorder (PTSD) NCT00908882 | US Department of Veterans Affairs | N/A |
| Completed | Bihar School Teachers Study NCT01722747 | Harvard School of Public Health (HSPH) | N/A |
| Completed | Low-Cost Contingency Management for Smoking Cessation NCT01040260 | University of California, San Francisco | N/A |
| Completed | MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use NCT01050465 | University of Missouri-Columbia | N/A |
| Completed | Concurrent Alcohol and Smoking Treatment: Effects on Alcohol Relapse Risk NCT00861146 | Yale University | Phase 2 |
| Completed | Natural History of Attempts to Stop Smoking NCT00995644 | University of Vermont | — |
| Completed | Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians NCT00608387 | Black Hills Center for American Indian Health | N/A |
| Completed | Study Evaluating The Efficacy Of Varenicline In Cessation Of Oral Smokeless Tobacco Use NCT00717093 | Pfizer | Phase 4 |
| Completed | Treating Tobacco Dependence in Adolescents With Co-occurring Psychiatric Disorders NCT00618943 | University of California, San Francisco | Phase 3 |
| Completed | Efficacy of Varenicline in Ambivalent Smokers NCT00595868 | University of Vermont Medical Center | Phase 2 |
| Completed | Community and Clinician Partnership for Prevention NCT00577759 | Duke University | N/A |
| Completed | Improving Varenicline Adherence and Outcomes in Homeless Smokers NCT00786149 | University of Minnesota | Phase 3 |
| Unknown | Tobacco Control Among Business Process Outsourcing (BPO) Employees NCT00617266 | Tata Memorial Hospital | Phase 3 |
| Completed | Quit and Fit: Teen Smoking Cessation NCT01242657 | West Virginia University | N/A |
| Completed | Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN) NCT00387946 | Sanofi | Phase 3 |
| Completed | Curbing Tobacco Use in Suburban and Rural Schools NCT00513097 | M.D. Anderson Cancer Center | Phase 1 |
| Completed | Treating Tobacco Dependence in Inpatient Psychiatry - 1 NCT00136812 | Stanford University | N/A |
| Completed | Tobacco Cessation Via Doctors of Chiropractic NCT00386945 | Oregon Research Institute | N/A |
| Completed | Smoking Cessation for Young Adults Who Binge Drink - 1 NCT00218452 | Mayo Clinic | EARLY_Phase 1 |
| Completed | Impact of Smoking Cessation on Sleep - 5 NCT00132821 | National Institute on Drug Abuse (NIDA) | Phase 4 |
| Completed | Smoking Treatment of Prisoners NCT00110630 | National Institute on Drug Abuse (NIDA) | Phase 3 |
| Completed | Group Therapy for Nicotine Dependence: Mindfulness and Smoking NCT00297479 | M.D. Anderson Cancer Center | N/A |
| Completed | Telephone Counseling for Snuff Users NCT00265681 | HealthPartners Institute | N/A |
| Completed | Safety and Effectiveness of NicVAX in Treating Nicotine Dependent Individuals NCT00218413 | Nabi Biopharmaceuticals | Phase 2 |
| Completed | Usefulness of Selegiline as an Aid to Quit Smoking - 1 NCT00129311 | Yale University | Phase 2 |
| Completed | Comparison of Standard Versus Extended Nicotine Patch Therapy for Smoking Cessation NCT00364156 | University of Pennsylvania | Phase 3 |
| Completed | Effectiveness of Bupropion for Treating Nicotine Dependence in Young People NCT00129272 | National Institute on Drug Abuse (NIDA) | Phase 2 |
| Completed | Tobacco Quitlines:Adjunct to Dental Office Tobacco Intervention NCT00384254 | Oregon Research Institute | Phase 2 |
| Completed | Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1 NCT00124683 | National Institute on Drug Abuse (NIDA) | Phase 2 |
| Completed | Efficacy and Cost of State Quitline Policies NCT00366977 | Kaiser Permanente | Phase 3 |