NCT05030194

Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study]

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Roswell Park Cancer Institute · Academic / Other
• Sex: All
• Age: 21 Years – 55 Years
• Healthy volunteers: Accepted

Summary

To pilot test the appeal of non-tobacco oral nicotine products in cigarette smokers, smokeless tobacco users, and oral nicotine users.

Detailed description

This study will assess the use, nicotine delivery, subjective response, and sensory appeal of an oral nicotine product (ZYN) compared to electronic nicotine delivery systems (ENDS, Vuse Alto) in cigarette smokers, smokeless tobacco users and oral nicotine users.

Conditions

• Tobacco Use
• Tobacco Smoking
• Cigarette Smoking
• Smokeless Tobacco Cessation

Interventions

Type	Name	Description
OTHER	Electronic Cigarette	Participants engage in 30 minutes of an oral nicotine product. In those 30 minutes the product can be used as much or as little as preferred.
OTHER	Oral Nicotine Pouch	Participants will be instructed to place a 6mg nicotine pouch in their mouth between gum and lip for up to 30 minutes.

Timeline

• Start date: 2021-10-21
• Primary completion: 2023-01-25
• Completion: 2023-01-25
• First posted: 2021-09-01
• Last updated: 2023-10-26

Locations

1 site across 1 country: United States