| Not Yet Recruiting | Varenicline for Smoking Reduction in Veterans Not Ready To Quit NCT06966362 | VA Office of Research and Development | Phase 4 |
| Not Yet Recruiting | Remote Interventions for Menthol Cigarette Use NCT07356297 | University of Michigan | N/A |
| Recruiting | Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit NCT07199517 | Abramson Cancer Center at Penn Medicine | N/A |
| Recruiting | Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing NCT07161050 | Virginia Polytechnic Institute and State University | N/A |
| Recruiting | Effects of Tax Proposals and Cigarette Availability on Tobacco Purchasing NCT07142668 | Virginia Polytechnic Institute and State University | N/A |
| Recruiting | Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults NCT06395415 | University of Chicago | N/A |
| Recruiting | Smoking Cessation for Fathers of Sick Children NCT07014124 | The University of Hong Kong | N/A |
| Recruiting | Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches NCT06678789 | Medical University of South Carolina | N/A |
| Recruiting | Effect of Cannabis on Cigarette Use Behavior NCT06609083 | Johns Hopkins University | Phase 1 |
| Recruiting | Beta-Adrenergic Modulation of Drug Cue Reactivity NCT05587361 | University of Oklahoma | Phase 4 |
| Recruiting | Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures NCT06295757 | Masonic Cancer Center, University of Minnesota | N/A |
| Completed | Lemongrass (Cymbopogon Citratus) on Nicotine Dependence, Cotinine Levels, and Related Biomarkers in Adult Smok NCT07366294 | Titin Andri Wihastuti | N/A |
| Recruiting | Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers NCT06372899 | Abramson Cancer Center at Penn Medicine | N/A |
| Completed | PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers NCT07316400 | University of Brawijaya | N/A |
| Recruiting | The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers NCT06264154 | Abramson Cancer Center at Penn Medicine | N/A |
| Recruiting | E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder NCT05722561 | NYU Langone Health | Phase 2 |
| Recruiting | Smoking Cessation Intervention for American Indian Women Experiencing Intimate Partner Violence NCT06357767 | Black Hills Center for American Indian Health | N/A |
| Completed | Examining the Generality of Laboratory-based Findings and Their Moderators in the ITC Study NCT06456671 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Testing the ETM: Examination and Comparison of Different Methods NCT05946031 | Virginia Polytechnic Institute and State University | EARLY_Phase 1 |
| Recruiting | Switch or Quit R01 NCT06373679 | Medical University of South Carolina | N/A |
| Completed | Sex Differences in E-cig Perception: Study 1 NCT05432830 | Yale University | N/A |
| Recruiting | Semaglutide for Post-Smoking Cessation Weight Management NCT06173778 | The University of Texas Health Science Center, Houston | Phase 2 |
| Recruiting | Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use NCT06027840 | Yale University | Phase 1 |
| Recruiting | Menthol, Inflammation, and Nicotine Transition Study NCT06232447 | Rosalind Franklin University of Medicine and Science | N/A |
| Recruiting | A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse NCT06118502 | Medical University of South Carolina | N/A |
| Completed | Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases NCT06001840 | Virginia Polytechnic Institute and State University | N/A |
| Completed | CAN-DOSE Study: Cessation With Augmented Nicotine for Dual Use Of Smoking and E-cigarettes NCT06087328 | Medical University of South Carolina | Phase 2 |
| Recruiting | E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness NCT05815199 | NYU Langone Health | N/A |
| Completed | Smoking, Stress, HIV and Mobile Technology NCT05709002 | University of Houston | N/A |
| Completed | Effects of Deep Breathing Exercise on Pulmonary Function, Perceived Stress and Physical Fitness Among Healthy NCT06032793 | Riphah International University | N/A |
| Enrolling By Invitation | Free Samples for Health NCT05627596 | Hennepin Healthcare Research Institute | Phase 2 |
| Completed | The Impact of Innovative Tax Proposals on Purchase Patterns NCT05370313 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Efficacy and Neuroimaging Mechanisms of Smoking Cessation in China NCT05788068 | Sir Run Run Shaw Hospital | N/A |
| Active Not Recruiting | Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks NCT05641974 | University of Colorado, Denver | N/A |
| Completed | E-Cigarettes and Financial Incentives to Promote Tobacco Harm Reduction Among Adults Accessing Shelter Service NCT03743532 | University of Oklahoma | N/A |
| Completed | Semaglutide for Alcohol Use Disorder NCT05520775 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Effects of Narratives on Demand for Low and High Ventilated Cigarettes and Substitution for Alternative Produc NCT05487625 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Comparison of the Substitution Between Different Tobacco/Nicotine Products as a Function of Tobacco-user Type NCT05177848 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Nicotine Withdrawal and Reward Processing NCT05041959 | University of Oklahoma | N/A |
| Completed | E-cigarettes for Harm Reduction in Adults With Asthma NCT05278065 | Brown University | N/A |
| Recruiting | Mobile Health Technology for Personalized Tobacco Cessation Support in Laos NCT05233228 | University of Oklahoma | Phase 2 |
| Completed | Mobile Health Technology for Personalized Tobacco Cessation Support Among Cancer Survivors in Laos NCT05253573 | University of Oklahoma | Phase 2 |
| Completed | Effects of e-Cigarettes on Perceptions and Behavior - Substudy 2 NCT05958966 | University of Southern California | N/A |
| Completed | Puff Biofeedback to Reduce Smoking Reinforcement NCT05644002 | Rutgers, The State University of New Jersey | N/A |
| Completed | Health-Kit Enabled Mobile App for Tobacco Cessation NCT06292130 | Pro-Change Behavior Systems | N/A |
| Completed | Incentives for Oklahoma Tobacco Helpline Engagement in Persistent Poverty Counties NCT05095779 | University of Oklahoma | Phase 2 |
| Completed | Impact of Nicotine Messaging on Beliefs and Behavior NCT05108649 | Andrew Strasser | N/A |
| Completed | Identify the Usefulness of In-person and Virtual Quit Smoking Programs NCT05181072 | Morgan State University | N/A |
| Active Not Recruiting | Are Smokers Switching to Vaping at Lower Risk for Cancer? (Electronic Cigarettes and Cancer Risk) NCT03750825 | University of Southern California | N/A |
| Completed | Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine NCT05030194 | Roswell Park Cancer Institute | N/A |
| Withdrawn | Impact of New Product Standards for JUUL Among Dual JUUL/Combusted Cigarette Users NCT04179617 | Duke University | N/A |
| Terminated | High Dose Bupropion for Smoking Cessation - Pilot Study NCT03326128 | University of Southern California | Phase 2 |
| Completed | The Effects of IQOS Use on Cigarette Smoking Behaviors NCT05076708 | University of Pennsylvania | EARLY_Phase 1 |
| Completed | Cigarette Smoking Among Young Adults NCT04340947 | University of Oklahoma | N/A |
| Completed | Effects of Choice Bundling on Valuation of Delayed Gains and Losses in Cigarette Smokers NCT05110716 | Virginia Polytechnic Institute and State University | N/A |
| Completed | BIDI Stick ENDS Abuse Liability and Puffing Topography Assessment NCT05072925 | BIDI Vapor | N/A |
| Completed | Mindfulness-based Smoking Cessation Enhanced With Mobile Technology NCT04965181 | Georgia State University | N/A |
| Terminated | Evaluation of the Added Value of Sophrology on the Intensity of Craving During Smoking Withdrawal NCT04700306 | Centre Hospitalier Intercommunal Creteil | N/A |
| Completed | Menthol and Mint Experimental Tobacco Marketplace (ETM) Study NCT04879225 | Wake Forest University Health Sciences | N/A |
| Completed | Ecological Momentary Intervention of Implementation Intentions Delivered by Text Message to Reduce Cigarette S NCT04967885 | Trustees of Dartmouth College | N/A |
| Recruiting | RTMS Targets Neural Circuits for Smoking Cessation NCT04903028 | Medical University of South Carolina | N/A |
| Completed | Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers NCT05279053 | University of California, Los Angeles | — |
| Completed | Efficacy of Smartphone App for Smoking Cessation in China NCT04421170 | Sir Run Run Shaw Hospital | N/A |
| Completed | A Study to Assess the Pharmacokinetics of Oral Nicotine Pouches and Lozenges in Healthy Adults NCT04755348 | British American Tobacco (Investments) Limited | N/A |
| Completed | STARS (Smoking Treatment And Remote Sampling) Study NCT04525755 | Medical University of South Carolina | Phase 1 / Phase 2 |
| Completed | E-cigarette Nicotine Study NCT04709471 | University of Vermont | Phase 2 |
| Completed | Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II Stud NCT04646174 | Rush University Medical Center | N/A |
| Completed | The Association of Cigarette Smoking on Exercise Capacity and Skeletal Muscle Function in Taiwan Adult Smokers NCT04688177 | National Taiwan University Hospital | — |
| Completed | THC Crossover Study NCT04429568 | University of California, San Francisco | N/A |
| Completed | Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder NCT04063267 | NYU Langone Health | Phase 2 |
| Completed | Families With Substance Use and Psychosis: A Pilot Study NCT04284813 | Mclean Hospital | N/A |
| Completed | Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 1 NCT05958979 | University of Southern California | N/A |
| Completed | Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2 NCT05958992 | University of Southern California | N/A |
| Completed | QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit A NCT04159571 | Wake Forest University Health Sciences | N/A |
| Completed | Goal2Quit + NRT Sampling NCT03837379 | Medical University of South Carolina | N/A |
| Recruiting | The Positively Quit Trial for Smoking Cessation NCT04449458 | University of South Florida | N/A |
| Completed | Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment NCT04461288 | University of California, San Francisco | N/A |
| Completed | 'WeChat WeQuit' Smoking Cessation Program NCT03169686 | Sir Run Run Shaw Hospital | N/A |
| Completed | E-Visit for COPD and Smoking Cessation NCT04155073 | Medical University of South Carolina | N/A |
| Completed | Effects of e-Cigarettes on Perceptions and Behavior - Substudy 1 NCT04399031 | University of Southern California | N/A |
| Terminated | Nicotine Withdrawal and Reward Processing: Connecting Neurobiology to Real-world Behavior NCT03840694 | Duke University | N/A |
| Completed | Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start Study NCT04043728 | Rush University Medical Center | N/A |
| Completed | Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes NCT04188197 | Rose Research Center, LLC | N/A |
| Terminated | Experimental Tobacco Marketplace in Regulating Flavored Tobacco Products in Menthol Cigarette Smokers NCT03897530 | Roswell Park Cancer Institute | N/A |
| Completed | Text Messaging-Based Smoking Cessation Program for Homeless Youth NCT03874585 | RAND | Phase 1 / Phase 2 |
| Completed | Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use NCT02870218 | Rose Research Center, LLC | Phase 2 |
| Completed | Effects of Random Nicotine Delivery on Smoking Cessation NCT03674970 | Milton S. Hershey Medical Center | Phase 1 / Phase 2 |
| Completed | Treating Smokers With Mental Illness NCT03822416 | University of Minnesota | Phase 2 |
| Completed | Evaluation of Ventilation Homogeneity as a Marker of Small Airway Disease in Active Smokers NCT03728712 | Centre hospitalier de l'Université de Montréal (CHUM) | — |
| Completed | A Study of Unfiltered Cigarettes Among Committed Smokers NCT03749876 | San Diego State University | N/A |
| Completed | Quit4Health Intervention in Supporting Smoking Cessation and Preventing Smoking Initiation in Young Adults NCT04009590 | M.D. Anderson Cancer Center | N/A |
| Withdrawn | Cognitive and Emotional Skills to Aid Smoking Cessation NCT03148652 | Boston University Charles River Campus | N/A |
| Unknown | Assessing Tobacco Product Choice When the Cost of Menthol Cigarettes Increases NCT03612349 | Brown University | N/A |
| Unknown | Curcumin; Rose Bengal; Denture Stomatitis NCT04837664 | King Saud University | Phase 3 |
| Completed | Behavioral Economic Methods for Assessing Tobacco Product Abuse Liability: Study 7 NCT03496922 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Cultural Adaptation and Piloting of a Smoking Cessation Intervention for Smokers With HIV NCT03580460 | Johns Hopkins University | N/A |
| Completed | Effects of Smoking Environments on Brain Reactivity NCT03421210 | Duke University | Phase 4 |
| Unknown | Investigation of Cigarette Cravings in Smokers NCT04843969 | Marco Leyton | N/A |
| Completed | Electronic Cigarette Use in Young Adult Men and Women NCT03089541 | Yale University | N/A |
| Terminated | Electroretinogram: a New Human Biomarker for Smoking Cessation Treatment NCT03213418 | New York State Psychiatric Institute | N/A |
| Completed | Neurobehavioral Substrates of Propranolol's Effects on Drug Cue Reactivity NCT03309943 | Duke University | Phase 4 |
| Completed | Smoking Topography Study 2018 NCT03498053 | Maastricht University Medical Center | N/A |
| Terminated | Intermittent Theta Burst for the Treatment of Alcohol Use Disorders in Veterans NCT03291431 | Stanford University | N/A |
| Completed | Exercise and Coronary Heart Disease Risk Markers in Male Smokers and Non-Smokers NCT03735186 | Loughborough University | N/A |
| Completed | e-Cigarette - DNA Adducts NCT03284632 | University of Minnesota | — |
| Completed | Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers NCT02906995 | Friends Research Institute, Inc. | Phase 1 |
| Completed | Reducing Tobacco Use Disparities Among Low-Income Adults NCT03077737 | Northwestern University | N/A |
| Completed | Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia NCT02420015 | Duke University | Phase 4 |
| Completed | New Approaches to Smoking Cessation in Heavy Drinkers NCT02151591 | Yale University | Phase 1 |
| Completed | iQuit Mindfully: Text Messaging for Smoking Cessation NCT03029819 | Georgia State University | N/A |
| Completed | Novel Approaches to Reducing Tobacco Related Harm NCT02600273 | Duke University | N/A |
| Completed | Nicotine Pharmacokinetics From Research Electronic Nicotine Delivery System S-TA-U001 in Smokers and E-Cigaret NCT02792426 | NJOY, Inc. | Phase 1 |
| Completed | Mobile Contingency Management for Marijuana and Tobacco Cessation NCT02869451 | Duke University | N/A |
| Completed | Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness NCT02845440 | Massachusetts General Hospital | N/A |
| Unknown | MapMySmoke: Smoking Cessation App With Geospatial Capture NCT02932917 | University of St Andrews | Phase 1 |
| Completed | Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia NCT02736474 | Shanghai Mental Health Center | Phase 4 |
| Terminated | Pilot Study of Nicotine Nasal Spray and Varenicline on Smoking in Methadone-Maintained Patients NCT02147132 | University of Cincinnati | Phase 4 |
| Completed | Investigation of Nicotine Seeking Behavior in Current Smokers NCT03670212 | Wayne State University | Phase 1 |
| Completed | Effects of Smoking Environments on Craving and Smoking (CameraCue2.0) NCT02551692 | Duke University | N/A |
| Completed | Strengthening Instrumental Extinction to Prevent Smoking Relapse (VLNCCue) NCT02538042 | Francis McClernon, Ph.D. | N/A |
| Withdrawn | Contingency Management for Smoking Cessation in Pregnant Minority Women NCT02195570 | University of Miami | N/A |
| Terminated | Pre to Postoperative Smoking Cessation NCT02683161 | Johns Hopkins University | Phase 2 |
| Unknown | Control Systems Approach to Predicting Individualized Dynamics of Nicotine Cravings NCT02643914 | Stony Brook University | N/A |
| Withdrawn | Effects of Varenicline in Heavy Drinking Smokers NCT02488889 | University of California, Los Angeles | Phase 4 |
| Completed | Financial Incentives for Smoking Cessation Among Mothers NCT05740098 | University of Vermont | N/A |
| Completed | A Smoking Cessation Study to Understand the Biological and Functional Changes After One Year of Smoking Cessat NCT02432729 | Philip Morris Products S.A. | — |
| Completed | The Impact of Orthopaedic Smoking Cessation Education on Cigarette Abstinence Self-Efficacy: A Randomized Cont NCT02408809 | University of Missouri, Kansas City | N/A |
| Completed | Enhancing Smoking Cessation in the Homeless Population NCT01932996 | University of Minnesota | Phase 4 |
| Completed | Text Messaging for Smoking Cessation in College Health Clinics NCT02191033 | Yale University | N/A |
| Completed | Project 1, Study 2: The Combined Impact of Nicotine Replacement and Spectrum Cigarettes NCT02301325 | Wake Forest University Health Sciences | N/A |
| Completed | Contingency Management, Quitting Smoking, and ADHD NCT02266784 | Duke University | Phase 1 |
| Completed | Developing a Smartphone App With Mindfulness Training for Teen Smoking Cessation NCT02218281 | University of Massachusetts, Worcester | N/A |
| Unknown | Sports, Education and Consumption of Substances in Adolescents NCT02629679 | University of Split | — |
| Completed | Characterization of Biomarkers of Tobacco Exposure, Urge-to-Smoke Following Exclusive and Dual Ad Lib Use of E NCT02385227 | Lorillard Tobacco Company | N/A |
| Unknown | Benefits of Tobacco Free Cigarette NCT02422914 | University of Milan | N/A |
| Completed | Varenicline + Prazosin for Heavy Drinking Smokers NCT02193256 | Yale University | EARLY_Phase 1 |
| Terminated | "Quit Smoking on Your Own" Brief Online Study NCT02103829 | i4Health | N/A |
| Completed | Mobile App Based Personalized Solutions and Tools for Medication Adherence of Rx Pills NCT02072005 | Duke University | — |
| Completed | Financial Incentives for Smoking Cessation Among Disadvantaged Pregnant Women NCT02210832 | University of Vermont | N/A |
| Completed | A Randomized Controlled Trial to Test the Effect of a Smartphone Quit Smoking Intervention on Young Adult Smok NCT01983150 | University of Waterloo | N/A |
| Completed | Postnatal Smoking Relapse, Its Associated Risk Factors, and a Proactive Sustainable Preventive Intervention NCT02258568 | Babes-Bolyai University | N/A |
| Completed | Resistance Training as an Aid to Smoking Cessation Treatment NCT01951456 | Teachers College, Columbia University | N/A |
| Withdrawn | Effects of Nicotine Replacement Therapy and D-cycloserine on Nicotine Treatment Seekers NCT01907594 | New York State Psychiatric Institute | Phase 2 |
| Completed | Comparative Effectiveness of Adding Weight Control to Smoking Cessation Quitlines NCT01867983 | Consumer Wellness Solutions | N/A |
| Active Not Recruiting | The Effectiveness of Smoking Cessation in Prediabetic Smokers NCT01926041 | National Taiwan University Hospital | N/A |
| Completed | Triclosan Toothpaste as a Preventive Strategy of Mucositis in Smokers NCT03241407 | Paulista University | N/A |
| Completed | Evaluation of National Cancer Institute Young Adult Stop-Smoking Program NCT01885052 | National Cancer Institute (NCI) | Phase 2 |
| Unknown | Step-up to Quit: Using Low-to-moderate Intensity Exercise for Reducing Smoking Cue Reactivity Among Low-income NCT02220465 | Temple University | Phase 1 |
| Completed | Innovative Web-Based Intervention for Smoking Cessation Among College Students NCT01982825 | Emory University | Phase 1 |
| Completed | Comparative Effectiveness of Post-Discharge Strategies for Hospitalized Smokers NCT01714323 | Massachusetts General Hospital | N/A |
| Completed | Smokers' Response to Nicotine Dependence Genotyping NCT01780038 | University of Nebraska | N/A |
| Completed | Contingency Management for Smoking Cessation in the Homeless NCT01736982 | UConn Health | N/A |
| Completed | Mechanisms of the Nicotine Metabolism Effect on Tobacco Dependence NCT01627392 | University of California, San Francisco | N/A |
| Completed | Tailored Tobacco Quitline for Rural Veterans NCT01592695 | Iowa City Veterans Affairs Medical Center | Phase 2 |
| Completed | The Effect of Smoking on Thermoregulation NCT01596556 | Sheba Medical Center | N/A |
| Completed | Comparison of Internet Stop Smoking Intervention to Usual Care on Smoking Cessation at 6 Months NCT01639079 | University of California, San Francisco | N/A |
| Completed | Biomarker Feedback for Smoking Cessation NCT02206971 | Masonic Cancer Center, University of Minnesota | N/A |
| Terminated | Tailored Smoking Cessation Treatment for LIVE FOR LIFE® Participants NCT01560507 | Duke University | Phase 2 / Phase 3 |
| Completed | Culturally Targeted & Individually Tailored Smoking Cessation Study: LGBT Smokers NCT01633567 | University of Illinois at Chicago | N/A |
| Unknown | Intervention Trial of Culturally-Appropriate Decision Aids for Smoking Cessation NCT01566097 | Seoul National University Hospital | N/A |
| Completed | Transcranial Direct Current Stimulation (tDCS) As A Treatment For Cigarette Craving and Cognitive Deficits in NCT02128919 | Nathan Kline Institute for Psychiatric Research | N/A |
| Completed | The Impact of Cigarette Smoking on Periodontal Therapy NCT05120206 | University of Bergen | N/A |
| Completed | Brain Nicotine Receptor Density & Response to Nicotine Patch NCT01526005 | Brentwood Biomedical Research Institute | — |
| Completed | Internet-Based Nonsmoking Program for Postpartum Women NCT02602730 | Oregon Center for Applied Science, Inc. | Phase 2 |
| Completed | Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster NCT02538601 | Stony Brook University | N/A |
| Completed | Quit Smoking With Nicotine Patch and Exercise/Health Education (Females Only) NCT01522274 | Brown University | N/A |
| Completed | Interactive Voice Response Technology to Mobilize Contingency Management for Smoking Cessation NCT01484717 | UConn Health | Phase 2 |
| Completed | Behavioral Intervention for Low Income Depressed Smokers in Drug Treatment NCT01372254 | University of Maryland, College Park | Phase 1 / Phase 2 |
| Completed | Pilot Study of Patient Navigation to Promote Smoking Cessation NCT01414036 | Boston University | N/A |
| Completed | Web-based Smoking Cessation Intervention: Transition From Inpatient to Outpatient NCT01277250 | University of Alabama at Birmingham | Phase 4 |
| Completed | Tailored Web and Peer Email Cessation Counseling for College Smokers NCT01604525 | University of Michigan | N/A |
| Completed | Mindfulness Training for Smokers Online Feasibility Study NCT02164656 | University of Wisconsin, Madison | Phase 2 |
| Completed | Smoking Cessation for Smokers With Sleep Problems NCT01277887 | Yale University | N/A |
| Completed | Behavioral Activation Intervention for Smoking Cessation in Smokers With Depressive Symptoms NCT01199380 | University of Maryland, College Park | Phase 2 |
| Completed | Internet-based Group Contingency Management to Promote Smoking Abstinence NCT01181661 | National Development and Research Institutes, Inc. | N/A |
| Completed | Smoking Interventions for Hospital Patients NCT01177176 | Massachusetts General Hospital | N/A |
| Completed | Development of Biomarkers of Effect From Chronic Tobacco Usage NCT01923402 | R.J. Reynolds Tobacco Company | — |
| Unknown | Working Inside for Smoking Elimination NCT01122589 | Memorial Hospital of Rhode Island | N/A |
| Completed | Contingency Management for Smoking Abstinence With Adolescent Smokers NCT01056588 | Nationwide Children's Hospital | N/A |
| Completed | Comparison of Low Yield Cigarettes in African Americans vs. Whites NCT01058876 | University of California, San Francisco | Phase 1 |
| Completed | STOP Study: Effectiveness of Zyban in a Clinical Population NCT01015170 | Centre for Addiction and Mental Health | Phase 4 |
| Completed | Naltrexone for At-Risk and Problem Drinking in Smoking Cessation Treatment NCT00938886 | Brown University | Phase 2 |
| Unknown | Your Health in On Click NCT03218670 | Marie-Pierre TAVOLACCI | — |
| Completed | Smoking Cessation Intervention in Public Housing NCT01035151 | Medical University of South Carolina | N/A |
| Completed | Technological Innovations in Behavioral Treatments for Cigarette Smoking NCT00926939 | National Development and Research Institutes, Inc. | N/A |
| Completed | A Study of Inhalation of 20,000 EU CCRE and Mucociliary Clearance (MCC) in Otherwise Healthy Individuals Who A NCT00924768 | University of North Carolina, Chapel Hill | Phase 1 |
| Completed | Improving the Delivery of Smoking Cessation Guidelines in Hospitalized Veterans NCT00816036 | US Department of Veterans Affairs | N/A |
| Completed | Smoking Study With Behavioral Therapy for Hypertensive Patients NCT00879177 | UConn Health | Phase 4 |
| Completed | Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smoke NCT00843622 | Swedish Match AB | Phase 4 |
| Completed | Mindfulness Training for Smoking Cessation NCT01144689 | Yale University | N/A |
| Completed | Treatment of Smoking Among Individuals With PTSD NCT00937235 | University of Pennsylvania | Phase 2 |
| Completed | Pharmacogenetics of Nicotine Metabolism in African-Americans NCT00879918 | University of California, San Francisco | Phase 1 |
| Completed | rTMS Effects on Smoking Cessation and Cognition in Schizophrenia NCT00736710 | Centre for Addiction and Mental Health | N/A |
| Completed | The Effectiveness of Smoking Cessation Guidelines in the Emergency Department NCT00756704 | University of Iowa | N/A |
| Completed | Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and Predictors NCT00802919 | Nathan Kline Institute for Psychiatric Research | Phase 4 |
| Completed | Cardiovascular Disease Biomarkers in Smokers and Moist Snuff Consumers NCT01692353 | R.J. Reynolds Tobacco Company | — |
| Completed | Brief Voluntary Alcohol and Drug Intervention for Middle School Youth NCT01081119 | RAND | Phase 2 |
| Completed | Using Computers to Assist in Parental Smoking Cessation in a Pediatric Setting NCT01334216 | Indiana University | N/A |
| Completed | Predictors of Teen Smoking-cessation NCT01141517 | Nationwide Children's Hospital | — |
| Completed | The Healthy Options Feasibility Study NCT00746460 | McGill University | N/A |
| Completed | Contingency Management and Pharmacotherapy for Smoking Cessation NCT00683280 | UConn Health | N/A |
| Completed | Contingency Management for Smoking in Substance Abusers NCT00683033 | UConn Health | Phase 2 |
| Completed | A Virtual Arm to Stop Smoking NCT00639093 | Universite du Quebec en Outaouais | N/A |
| Completed | Reaching and Treating Lesbian, Gay, Bisexual, and Transgender (LGBT) Cigarette Smokers NCT00634218 | University of California, San Francisco | Phase 2 / Phase 3 |
| Completed | Serbian Smoking Reduction/Cessation Trial (2SRT) NCT00601042 | Swedish Match AB | Phase 4 |
| Completed | Knowledge and Perception of Smoking Risks/Consequences NCT00686101 | University of Maryland, Baltimore | — |
| Completed | Comparison of Varenicline and Placebo for Smoking Cessation in Schizophrenia NCT00554840 | University of Maryland, Baltimore | Phase 2 |
| Completed | Gabapentin for Smoking Cessation NCT00578552 | Mayo Clinic | Phase 2 |
| Completed | Concurrent Nicotine Patch / Denicotinized Cigarette Therapy for Smoking Cessation II NCT00734617 | Duke University | Phase 3 |
| Completed | Use and Harm Exposure in New Low Nicotine Cigarettes NCT01202942 | University of Pennsylvania | N/A |
| Completed | Switching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or Snus NCT02061917 | R.J. Reynolds Tobacco Company | N/A |
| Completed | Mood Management Phone Counseling in Smoking Cessation NCT00500877 | Butler Hospital | Phase 2 |
| Completed | School Nurse-Delivered Smoking Cessation Intervention NCT00682474 | University of Massachusetts, Worcester | Phase 2 / Phase 3 |
| Terminated | Analysis of Lipid Biomarkers of Exposure and Host Response NCT00493831 | University of Nebraska | N/A |
| Completed | Practicing Self-Control Lowers the Risk of Smoking Lapse NCT00349687 | University at Albany | N/A |