NCT05076708

The Effects of IQOS Use on Cigarette Smoking Behaviors

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 102 (actual)
• Sponsor: University of Pennsylvania · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This within-subjects study aims to evaluate the effects of IQOS use on combustible cigarette smoking behaviors among 100 cigarette smokers who completed the study. After measuring baseline cigarette smoking rate, participants will receive an IQOS device and be instructed to use it (versus cigarettes) over a 14-day period. The investigators will also examine which objective and subjective effects of IQOS use predict a complete and incomplete switch from cigarettes to IQOS.

Conditions

• Smoking
• Cigarette Smoking
• Tobacco Use

Interventions

Type	Name	Description
OTHER	IQOS	All participants switch from cigarette smoking to IQOS use for a 14-day phase.

Timeline

• Start date: 2021-08-26
• Primary completion: 2024-02-01
• Completion: 2024-05-31
• First posted: 2021-10-13
• Last updated: 2025-02-03
• Results posted: 2025-02-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study