NCT05308316

Sugars in Cigarettes

Impact of Sugars on Tobacco Product Toxicity and Abuse Liability

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Masonic Cancer Center, University of Minnesota · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to investigate the impact of sugar levels in cigarette tobacco on cigarette abuse liability and appeal. Participants will attend several clinic visits to smoke cigarettes with different levels of sugars and will complete multiple questionnaires to assess their experiences. Each of the sessions will be separated by at least 48 hours but not more than 5 days. The hypothesis is that the measures collected in this study will indicate lower abuse liability for cigarettes with lowest sugar content.

Conditions

• Tobacco Use

Interventions

Type	Name	Description
OTHER	Cigarettes with added sucrose	Winston brand cigarettes will be modified by adding sucrose to each cigarette at 2 levels so that the amount of total (originally present and added) sugar content in these cigarettes matches median and highest levels found in popular cigarette brands.

Timeline

• Start date: 2022-02-24
• Primary completion: 2023-10-13
• Completion: 2025-10-09
• First posted: 2022-04-04
• Last updated: 2026-02-27
• Results posted: 2026-01-06

Locations

1 site across 1 country: United States