Clinical Trials Directory

Trials / Completed

CompletedNCT03007394

Lorcaserin in the Treatment of Cocaine Use Disorder

Phase 2, Multi-Center Trial of Lorcaserin in the Treatment of Cocaine Use Disorder

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
272 (actual)
Sponsor
National Institute on Drug Abuse (NIDA) · NIH
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The objective of this study is to evaluate the efficacy and safety of lorcaserin in the treatment of cocaine use disorder.

Detailed description

This is a 19-week, multi-center, randomized, Phase 2 clinical study comparing the efficacy of lorcaserin (10mg, b.i.d) to matched placebo in the treatment of cocaine use disorder. Up to 3 weeks will be allowed for the Screening Period and a 13-week treatment phase, with a 3-week follow-up period, with scheduled visits during Study weeks 14 and 16.

Conditions

Interventions

TypeNameDescription
DRUGLorcaserinLorcaserin Capsule
DRUGPlacebo Oral Capsulesugar pill to mimic lorcaserin 10mg capsule

Timeline

Start date
2017-12-19
Primary completion
2019-12-01
Completion
2019-12-01
First posted
2017-01-02
Last updated
2020-08-05
Results posted
2020-06-19

Locations

12 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03007394. Inclusion in this directory is not an endorsement.