NCT00087880

Maintaining Abstinence in Chronic Cigarette Smokers - 1

Maintaining Abstinence in Chronic Cigarette Smokers

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 407 (actual)
• Sponsor: National Institute on Drug Abuse (NIDA) · NIH
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the extended pharmacological and psychological treatment for chronic cigarette smokers.

Detailed description

The work adapts interventions that have been successful in the general populations, and tailors them to chronic smokers, who may have numerous previous smoking treatment failures. If successful it will: (1) make available a treatment intervention that produces hight long term abstinence rates; (2) provide information on variables that predicts success and failure in this population of smokers; (3) examine the cost-effectiveness of more intensive, longer term treatments.

Conditions

• Tobacco Use Disorder

Interventions

Type	Name	Description
DRUG	Bupropion and NRT	All participants receive standard 12 week treatment of NRT, bupropion and five group counseling sessions. At week 11, subjects are randomly assigned to one of five treatment groups (1) Bupropion/Low Contact; (2) Placebo/Low Contact; (3) Bupropion/Relapse Prevention; (4) Placebo/Relapse Prevention; (5) No Further Treatment. Data is collected at Week 0, and at weeks 12, 24, 52, 64, and 104.

Timeline

• Start date: 2002-12-01
• Primary completion: 2005-01-01
• Completion: 2009-09-01
• First posted: 2004-07-19
• Last updated: 2017-01-12

Locations

1 site across 1 country: United States