NCT03595293

fNIRs-based Neurofeedback to Reduce Relapse in pOUD/AUD

Functional Near Infrared Spectroscopy-based Neurofeedback to Reduce Relapse in Prescription Opioid/Alcohol Use Disorders

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Milton S. Hershey Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will examine the impact of functional near-infrared spectroscopy-based neurofeedback to a region within the brain's prefrontal cortex involved with self-regulation of resisting craving in alcohol use and prescription opioid use disorder patients. Participants will be asked to complete two cue reactivity tasks, six sessions of neurofeedback training as well as craving visual analog scales and self-efficacy questionnaires throughout a two-week period of their time in residential treatment at the Caron Treatment Center. They will be followed for 90 days after treatment completion at Caron to assess the impact neurofeedback had on their ability to remain sober once patients are living back in the "real world".

Conditions

• Alcohol Use Disorder
• Alcoholism
• Prescription Drug Dependence
• Opioid-use Disorder
• Neurofeedback

Interventions

Type	Name	Description
DEVICE	fNIRs-based Neurofeedback	Patients receive fNIRs-based neurofeedback from the rDLPFC to allow them to modify activation within this area.
DEVICE	Sham feedback	Patients receive fNIRs-based sham feedback from the left zygomatic area to allow them to modify activation within this area.

Timeline

• Start date: 2026-01-01
• Primary completion: 2027-02-01
• Completion: 2028-02-01
• First posted: 2018-07-23
• Last updated: 2024-12-20