| Not Yet Recruiting | Adapting a Telehealth Intervention for Suicide Prevention Among Patients With Alcohol Use Disorder in Tanzania NCT07475988 | Duke University | N/A |
| Not Yet Recruiting | A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention A NCT07214831 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | Pilot Study: Effects of Nimodipine on Alcohol Drinking NCT06900998 | Yale University | Phase 2 |
| Not Yet Recruiting | Financial Rewards for Reducing Alcohol Use in Patients With Liver Disease NCT07465588 | Massachusetts General Hospital | N/A |
| Not Yet Recruiting | Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized, Double-Blind, Placebo-Controlled Phas NCT07218354 | VA Office of Research and Development | Phase 3 |
| Not Yet Recruiting | Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya NCT06790342 | University of Chicago | Phase 3 |
| Not Yet Recruiting | Endotoxin Exposure to Examine the Role of Inflammation in Alcohol Use NCT07452146 | University of California, Los Angeles | Phase 2 |
| Not Yet Recruiting | Peer Support for Liver Transplant Recipients With History of ALD NCT07397598 | Johns Hopkins University | N/A |
| Not Yet Recruiting | GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver Dise NCT06546384 | Insel Gruppe AG, University Hospital Bern | N/A |
| Not Yet Recruiting | Social Cognition in Severe Alcohol Use Disorder NCT07464613 | CHU de Reims | N/A |
| Not Yet Recruiting | Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder NCT07296094 | Brigham and Women's Hospital | Phase 2 |
| Not Yet Recruiting | Combination Therapy for Alcohol Use Disorder NCT07249554 | Johns Hopkins University | Phase 2 |
| Not Yet Recruiting | Methylphenidate and Response to Alcohol Cues NCT07306078 | University of Florida | Phase 2 |
| Recruiting | Environment and Alcohol: A Pilot Study NCT06860607 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Not Yet Recruiting | Hepatic Lipid Metabolism-Alcohol Use Disorder NCT07191561 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Not Yet Recruiting | MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder NCT07118839 | VA Office of Research and Development | Phase 2 / Phase 3 |
| Recruiting | Human Laboratory Study of Apremilast for Alcohol Use Disorder NCT07325266 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Not Yet Recruiting | Impact of Federal and State Medications for Opioid Use Disorder (MOUD) Policy Changes During the Pandemic NCT07232641 | Boston University | — |
| Not Yet Recruiting | LDART for Alcohol Use Disorder NCT07221383 | Yale University | N/A |
| Recruiting | Tirzepatide in MetALD NCT07046819 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Not Yet Recruiting | Phase 2 Study of Apremilast in Women and Men With Alcohol Use Disorder NCT07029529 | Yale University | Phase 2 |
| Not Yet Recruiting | Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use Disorder NCT07468825 | Assistance Publique - Hôpitaux de Paris | — |
| Not Yet Recruiting | Implementation Facilitation Pilot for Alcohol Use Disorder (AUD) in Alcohol-associated Liver Disease (ALD) NCT07525258 | Yale University | N/A |
| Recruiting | Cannabidiol and Alcohol Use Disorder Phenotypes NCT07279558 | University of Colorado, Denver | Phase 2 |
| Recruiting | Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis NCT07056894 | Nova Scotia Health Authority | N/A |
| Recruiting | Study of NTX-2001 on Alcohol Consumption in Alcohol Use Disorder NCT07520292 | Newleos Therapeutics, Inc. | Phase 1 |
| Not Yet Recruiting | The Connect Trial: Connecting Hospital Patients to Alcohol Care NCT07482150 | Zealand University Hospital | N/A |
| Not Yet Recruiting | Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS) NCT07223983 | Yale University | Phase 1 |
| Not Yet Recruiting | Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study NCT07001371 | Loma Linda University | N/A |
| Not Yet Recruiting | Cognitive and Metacognitive Remediation in Addiction Treatment. NCT07390877 | Nantes University Hospital | N/A |
| Recruiting | Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD) NCT07413458 | University of Michigan | N/A |
| Not Yet Recruiting | Transcranial Temporal Interference Stimulation Targeted of the Amygdala as an Intervention for Alcohol Use Dis NCT07472673 | Shanghai Mental Health Center | N/A |
| Recruiting | Piloting a Deaf Accessible Pre-Treatment for AUD NCT07269119 | University of Massachusetts, Worcester | N/A |
| Not Yet Recruiting | Administration of Fiber as a Dietary Supplement to Improve the Management of Alcohol Withdrawal NCT07371286 | Assistance Publique - Hôpitaux de Paris | N/A |
| Not Yet Recruiting | Effects of Ketones on Brain Energetics and Alcohol Consumption in Alcohol Use Disorder NCT06807918 | University of Pennsylvania | Phase 2 / Phase 3 |
| Recruiting | tAN for Substance Use Disorder NCT07281261 | Spark Biomedical, Inc. | N/A |
| Recruiting | Better Experiences in Substance Treatment: A Brief Alcohol-focused Intervention Tailored for Patients in Opioi NCT07342504 | University of Notre Dame | N/A |
| Not Yet Recruiting | Coordinated Care for Alcohol Problems NCT07260149 | Sangath | N/A |
| Withdrawn | fNIRs-based Neurofeedback to Reduce Relapse in pOUD/AUD NCT03595293 | Milton S. Hershey Medical Center | N/A |
| Active Not Recruiting | Probiotic Study in Alcohol Recovery NCT07510113 | Loughborough University | N/A |
| Recruiting | Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B) NCT07027839 | National Institute of Mental Health (NIMH) | Phase 1 |
| Recruiting | Mobile Platform for Optimizing Wellness and Engagement in Recovery NCT07178990 | University of Michigan | N/A |
| Recruiting | Orexin Receptor Antagonism for the Treatment of Alcohol Use Disorder and Stress-Related Drinking NCT07214207 | Ohio State University | Phase 2 |
| Recruiting | A Randomized Controlled Trial of Digital CBT to Treat Addiction: Digital RITch®CBT vs. Standard CBT NCT05943171 | University of Rochester | N/A |
| Recruiting | Alcohol Misuse Treatment to Patients Newly Diagnosed With Alcohol-related Liver Disease: a Randomized Controll NCT06493773 | Zealand University Hospital | N/A |
| Recruiting | Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of A NCT07216872 | Brainsway | N/A |
| Recruiting | A Study of Brenipatide in Participants With Alcohol Use Disorder NCT07219953 | Eli Lilly and Company | Phase 3 |
| Recruiting | A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder NCT07219966 | Eli Lilly and Company | Phase 3 |
| Recruiting | Tirzepatide for Alcohol Use Disorder NCT06994338 | University of Southern California | Phase 2 |
| Recruiting | A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder NCT05621538 | Auburn University | N/A |
| Not Yet Recruiting | TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD) NCT07171359 | Washington State University | N/A |
| Recruiting | Anxiety During Abstinence in AUD NCT06793488 | Columbia University | EARLY_Phase 1 |
| Recruiting | Guanfacine for Alcohol Use Disorder (AUD) NCT06629259 | Indiana University | Phase 2 |
| Recruiting | Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD NCT06349083 | NYU Langone Health | Phase 2 |
| Recruiting | Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder NCT06415721 | VA Palo Alto Health Care System | N/A |
| Recruiting | Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder NCT06559995 | University of Pennsylvania | Phase 2 / Phase 3 |
| Recruiting | Deep Brain Stimulation to Understand and Treat Addiction NCT07341230 | University of Cambridge | N/A |
| Recruiting | Evaluating a One-Year Version of the Parent-Child Assistance Program NCT06163651 | University of Oklahoma | N/A |
| Recruiting | Reducing Hazardous Alcohol Use and Optimizing Treatment as Prevention Among Men Living With HIV in Risk Enviro NCT06771843 | San Diego State University | N/A |
| Active Not Recruiting | Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2 NCT06006143 | Yale University | Phase 2 |
| Recruiting | Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial NCT06405607 | University of Iowa | Phase 2 |
| Recruiting | Self-Concept and Autobiographical Memory in Alcohol Use Disorder NCT06985927 | CHU de Reims | N/A |
| Recruiting | The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration NCT06319872 | University of Rochester | Phase 1 |
| Recruiting | rTMS as Add on Treatment for Substance Use Disorders NCT06963476 | Yale University | N/A |
| Recruiting | Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder NCT06269627 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 4 |
| Recruiting | Involvement of the Septal Nuclei of the Human Brain in Alcohol Use Disorder NCT06866379 | Anders Fink-Jensen, MD, DMSci | N/A |
| Recruiting | Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder NCT06939088 | Anders Fink-Jensen, MD, DMSci | Phase 2 |
| Recruiting | Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC NCT06864819 | University Hospitals Cleveland Medical Center | — |
| Recruiting | ACT_for Alcohol Use Disorder and Depression NCT06620276 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Recruiting | A First in Human Study of CMND-100 in Healthy and Alcohol Use Disorder (AUD) Subjects NCT05913752 | Clearmind Medicine Inc. | Phase 1 / Phase 2 |
| Not Yet Recruiting | Towards a Targeted Ultrasound Neuromodulation Intervention for Alcohol Abuse Disorders NCT06894966 | University of Plymouth | N/A |
| Withdrawn | An Effectiveness Trial of the PrEP for WINGS Study NCT06853314 | Columbia University | N/A |
| Recruiting | Nutritional Intervention to Reduce Alcohol Consumption NCT06787235 | University of Bern | N/A |
| Recruiting | A Novel Blood Test as a Biomarker in Mental Health NCT06856161 | Fraser Health | — |
| Recruiting | Systematic Implementation of Patient-centered Care for Alcohol Use Trial: Beyond Referral to Treatment NCT06318026 | Kaiser Permanente | N/A |
| Recruiting | Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study NCT06770556 | Wake Forest University Health Sciences | N/A |
| Recruiting | PET Imaging of Phosphodiesterase-4B (PDE4B) in Alcohol Use Disorder NCT06795581 | National Institute of Mental Health (NIMH) | Phase 1 |
| Completed | Drivers of Suicide Mobile App Study NCT05427734 | Evidence-Based Practice Institute, Seattle, WA | N/A |
| Active Not Recruiting | Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybi NCT07189988 | Healing Advocacy Fund | — |
| Recruiting | Intranasal Insulin for Treatment of Alcohol Use Disorder NCT05988632 | Brown University | Phase 1 / Phase 2 |
| Recruiting | A Non-Inferiority Trial of an Electronic vs Face-to-face Brief Intervention After Alcohol Screening in Two Cou NCT07150156 | HBSA | N/A |
| Enrolling By Invitation | Counseling for Alcohol Problems in Pregnancy (CAP-Pre) Phase II NCT06853873 | Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH | N/A |
| Active Not Recruiting | A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder NCT06817356 | Eli Lilly and Company | Phase 2 |
| Recruiting | Image-guided, Robot Navigated Transcranial Magnetic Stimulation (IR-TMS) for Alcohol Use Disorder (AUD) NCT06648642 | The University of Texas Health Science Center at San Antonio | N/A |
| Recruiting | PT150 Drug for Use in Alcohol Use Disorder NCT06712602 | Pop Test Oncology LLC | Phase 1 |
| Completed | Study of Sunobinop on Craving in Alcohol Use Disorder NCT06545929 | Imbrium Therapeutics | Phase 2 |
| Recruiting | Electronic Harm Reduction Treatment for Alcohol NCT06702007 | University of Washington | Phase 3 |
| Completed | Adapting and Piloting Behavioral Activation for Veterans With Alcohol Use Disorder and Posttraumatic Stress Di NCT06249386 | RTI International | N/A |
| Recruiting | The Impact of Heavy Alcohol Use on Saliva and Oral Health NCT06684483 | National Institutes of Health Clinical Center (CC) | — |
| Recruiting | Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder NCT06518785 | University of California, San Francisco | N/A |
| Recruiting | Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcoho NCT06399653 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Ketamine for Combined Depression and Alcohol Use Disorder NCT06090422 | University Hospital of North Norway | Phase 1 / Phase 2 |
| Recruiting | Motivational Interviews Post Hospitalisation on Maintaining AbstiNence for 1 Year après le Sevrage en Alcool NCT06618755 | University Hospital, Montpellier | N/A |
| Recruiting | TRAC-ER Intervention to Reduce Risky Alcohol Use and HIV Risk NCT05576350 | University of Kentucky | N/A |
| Recruiting | Integrated Treatment for Enhancing Growth in Recovery During Adolescence NCT06395467 | Massachusetts General Hospital | N/A |
| Recruiting | New Relapse Model in Psychiatry NCT06244641 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Recruiting | Validation of the French Version of the Prediction of the Alcohol Withdrawal Severity Scale (PAWSS) NCT06675539 | Etablissement Public de Santé Barthélemy Durand | — |
| Recruiting | Drinking, Acetate, and Stress NCT06584448 | Yale University | N/A |
| Recruiting | Developing a Novel Human Laboratory Paradigm for AUD Medication Screening NCT06489782 | Yale University | N/A |
| Recruiting | Cannabidiol for Reducing Drinking in Alcohol Use Disorder NCT05159830 | Hôpital le Vinatier | Phase 2 |
| Recruiting | Effect of Adapted Physical Activity on Sleep Quality in People With Alcohol Use Disorder NCT06706349 | Centre Hospitalier Universitaire de Besancon | N/A |
| Active Not Recruiting | Study of Sunobinop on Alcohol Consumption in Alcohol Use Disorder NCT06545916 | Imbrium Therapeutics | Phase 2 |
| Not Yet Recruiting | Effect of Social Isolation on the Role of Pavlovian Mechanisms for Control Over Alcohol Use NCT06256952 | Charite University, Berlin, Germany | N/A |
| Not Yet Recruiting | Peer Support in Alcohol Dependence NCT06381609 | Hospices Civils de Lyon | N/A |
| Recruiting | Citicoline in Youth Alcohol Use Disorder NCT05870111 | Medical University of South Carolina | Phase 2 |
| Completed | Enhancing the Effects of Alcohol Treatment With L-Carnitine NCT05355311 | Brown University | Phase 1 |
| Recruiting | Modification of Inhibitory Control and Craving Through Transcranial Direct Current Stimulation (tDCS) as an Ad NCT06959342 | Central Institute of Mental Health, Mannheim | N/A |
| Active Not Recruiting | CM for Patients With ALD After Liver Transplant NCT06304467 | Arpan A. Patel, MD | N/A |
| Active Not Recruiting | The STop UNhealthy Substance Use Now Trial NCT06524232 | Ohio State University | N/A |
| Active Not Recruiting | Effectiveness of Internet-Based Self-Help ACT With Behavioral Activation in Improving Alcohol Use Abstinence A NCT06779006 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP NCT06552741 | National Institute on Drug Abuse (NIDA) | — |
| Not Yet Recruiting | Mobile App Intervention for Sleep Problems and Alcohol Use Among Veterans NCT06487793 | University of Southern California | N/A |
| Not Yet Recruiting | Preventing Alcohol Use Disorders and Alcohol-Related Harms in Pacific Islander Young Adults NCT06337721 | University of California, Riverside | N/A |
| Not Yet Recruiting | Psilocybin-assisted Therapy for Alcohol Use Disorder NCT06444243 | University of Sydney | Phase 2 |
| Recruiting | Emergency Department-Initiated Medications for Alcohol Use Disorder NCT05827159 | Yale University | Phase 3 |
| Recruiting | Evaluating Cannabidiol as a Novel Anticraving Medication for Alcohol Use Disorder NCT06512389 | Centre for Addiction and Mental Health | Phase 2 |
| Active Not Recruiting | Diclofenac as a KMO Inhibitor NCT06029296 | University of Maryland, Baltimore | EARLY_Phase 1 |
| Enrolling By Invitation | Peer Delivered, Emotion Regulation-Focused Mental Health Prevention Training for Fire Fighter Trainees NCT06290778 | Baylor Research Institute | N/A |
| Unknown | Treating Stress and Anxiety in Individuals With Alcohol Use Disorder (AUD) NCT06224127 | Soovu Labs Inc. | Phase 1 |
| Recruiting | Emergency Medicine Peer Outreach Worker Engagement for Recovery NCT06320015 | University of California, Los Angeles | — |
| Not Yet Recruiting | Emotional Attention Bias Modification and Targeted Memory Reactivation in Alcohol Use Disorder NCT06457113 | Shanghai Mental Health Center | N/A |
| Suspended | Decision Making in Chronic Pain and Alcohol Use Disorder NCT05901610 | Virginia Polytechnic Institute and State University | N/A |
| Active Not Recruiting | Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk NCT05828849 | NYU Langone Health | N/A |
| Withdrawn | Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain Injur NCT06380985 | VA Office of Research and Development | N/A |
| Completed | Brief Contextual-Behavioral vs Twelve-Step Intervention for Emotion Regulation in Substance Use: Pilot Study NCT07337733 | Lauro Gutiérrez Castro | N/A |
| Recruiting | Virtual Incentive Treatment for Alcohol NCT06265506 | Washington State University | N/A |
| Recruiting | Enhancing Prospective Thinking in Early Recovery (BEAM) NCT06283472 | Indiana University | N/A |
| Recruiting | A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners NCT05619185 | Stanford University | N/A |
| Completed | The Effectiveness of a Mobile Game Intervention in Alcohol Use Disorder NCT07103785 | University of Yalova | N/A |
| Recruiting | Automated Reinforcement Management Systems, Phase II NCT06456905 | Washington State University | N/A |
| Recruiting | Suvorexant and Alcohol NCT06326684 | William Stoops | EARLY_Phase 1 |
| Recruiting | Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat NCT06371404 | Yale University | — |
| Recruiting | Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease NCT06305624 | University of Wisconsin, Madison | N/A |
| Active Not Recruiting | Apremilast for Alcohol Use Disorder Treatment in Women and Men NCT06324435 | Yale University | Phase 1 |
| Recruiting | Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alco NCT06426303 | Milky Kohno | Phase 4 |
| Completed | Brain Connectivity Between Networks Implied in Inhibition and Cue-reactivity in Alcohol Use Disorder NCT05843435 | University of Bern | — |
| Not Yet Recruiting | Tracking Mood: The Effects of Daily Mood Tracking VAS on Alcohol Consumption in Adult Heavy Drinkers NCT06419647 | Ilona Myllyniemi | N/A |
| Recruiting | A Peer Recovery Coaching Intervention for Hospitalized Alcohol Use Disorder Patients NCT06479681 | Clemson University | N/A |
| Completed | A Study to Assess the Pharmacokinetic Profile of Prazosin and Cyproheptadine NCT06147622 | Kinnov Therapeutics | Phase 1 |
| Completed | Pilot Trial to Evaluate PROblem Solving Therapy and APPLE Watch for College Students NCT06333288 | University of Illinois at Chicago | N/A |
| Completed | Integration of Neurofunctional Phenotyping Into Investigation of CBT4CBT for AUD NCT06190236 | Virginia Commonwealth University | N/A |
| Recruiting | Alcohol and the Social Brain: an Alcohol-Administration Hyperscanning Study NCT06687525 | University of Illinois at Urbana-Champaign | — |
| Recruiting | Impulsivity Domains and Subjective Response NCT05929677 | Jessica Weafer | EARLY_Phase 1 |
| Recruiting | Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD NCT05959434 | Texas A&M University | Phase 2 |
| Recruiting | Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder NCT05995769 | University of Calgary | Phase 2 |
| Completed | Methylphenidate and Response to Alcohol Cues Pilot Study NCT06063200 | University of Florida | EARLY_Phase 1 |
| Recruiting | Effect of Repetitive TMS on Executive Function in Alcohol Use Disorder NCT05997212 | Universidad Nacional Autonoma de Mexico | N/A |
| Active Not Recruiting | Implementation of a Digital Clinic for Alcohol-associated Liver Disease and Alcohol Use Disorder (DALC) NCT06319222 | Mayo Clinic | N/A |
| Enrolling By Invitation | Effects of Ketone Supplementation on Acute Alcohol Withdrawal NCT06173973 | University of Pennsylvania | Phase 2 / Phase 3 |
| Recruiting | Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection NCT06139224 | Rush University Medical Center | N/A |
| Not Yet Recruiting | Identification of Cellular and Molecular Mechanisms Involved in the Pathophysiology of Alcohol Use Disorder by NCT06286449 | Vastra Gotaland Region | N/A |
| Recruiting | Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship NCT05786157 | Medical University of South Carolina | N/A |
| Recruiting | Enhancing Prospective Thinking in Early Recovery (HOME) NCT06302413 | Indiana University | N/A |
| Completed | Study of Prevalence of Eating Disorder in Liver Transplant Patients NCT06093919 | Centre Hospitalier Henri Laborit | — |
| Recruiting | MDMA for AUD/PTSD Comorbidity NCT05943665 | Carolina L Haass-Koffler | Phase 2 |
| Active Not Recruiting | Psilocybin-Assisted vs Ketamine-Assisted Psychotherapy for Alcohol Use Disorder NCT05421065 | Peggy C Nopoulos | Phase 2 |
| Active Not Recruiting | Telehealth Treatment for Alcohol Use Disorder NCT05747703 | Ria Health | N/A |
| Withdrawn | Using Transcutaneous Auricular Vagus Nerve Stimulation to Treat Acute Alcohol Withdrawal NCT04159909 | Northwell Health | N/A |
| Active Not Recruiting | Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder NCT05902754 | Louisiana State University Health Sciences Center in New Orleans | N/A |
| Recruiting | Motivation for IV Alcohol Self-Administration in Humans NCT06494891 | University of California, Los Angeles | Phase 2 |
| Completed | Clinical Trial of Rybelsus (Semaglutide) Among Adults With Alcohol Use Disorder (AUD) NCT05892432 | University of Colorado, Denver | Phase 2 |
| Recruiting | Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD) NCT05677321 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Suspended | The Effects of Sex Hormones and Alcohol on Sleep NCT06143059 | Lauren Whitehurst | Phase 3 |
| Recruiting | Pregnenolone for the Treatment of Alcohol Use Disorder NCT05781009 | Yale University | Phase 2 |
| Completed | The Pocket Skills Adjunct Project NCT06402240 | University of Windsor | N/A |
| Withdrawn | aTBS for Treatment of Depression in AUD NCT03981185 | Stanford University | N/A |
| Recruiting | Alcohol Use Disorder Before and After Bariatric Surgery and the Impact of Considering This Surgery During Addi NCT07273955 | University Hospital, Strasbourg, France | — |
| Recruiting | Translation and Validation of the COMM and ASI-SR NCT06084520 | Uppsala University | — |
| Recruiting | Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder NCT06105853 | Central Institute of Mental Health, Mannheim | N/A |
| Completed | EMPOWER AUD Pivotal Trial NCT05948605 | Theranova, L.L.C. | N/A |
| Recruiting | Investigating the Mu:Kappa Opioid Receptor Imbalance in Alcohol Use Disorder NCT05957159 | Yale University | EARLY_Phase 1 |
| Active Not Recruiting | Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1 NCT06004830 | Yale University | Phase 2 |
| Active Not Recruiting | rTMS in Older Adults With MCI and AUD NCT05896332 | Medical University of South Carolina | Phase 1 |
| Withdrawn | Oxytocin on Approach Bias and Craving NCT03865615 | Jennifer Mitchell | Phase 2 |
| Terminated | Experimental Study on Alcohol Use and Behavior in Young Adults NCT06199076 | Karolinska Institutet | Phase 2 |
| Recruiting | Semaglutide Therapy for Alcohol Reduction (STAR) NCT06015893 | National Institute on Drug Abuse (NIDA) | Phase 2 |
| Recruiting | Harmony: A Combined MI and BCT Intervention to Reduce Intimate Partner Violence and Alcohol Use in South India NCT05893277 | University of California, San Francisco | N/A |
| Recruiting | Cerebellar Involvement in Alcohol Use Disorder (AUD) NCT05732207 | Johns Hopkins University | N/A |
| Recruiting | Testing a PTSD m-Health Intervention to Improve Alcohol Treatment Outcomes NCT05564663 | Michigan State University | N/A |
| Completed | Compensatory Cognitive Training Via Telehealth for Veterans With Alcohol Use Disorders NCT06134128 | Portland VA Medical Center | N/A |
| Completed | Theta Burst Stimulation for Alcohol Use Disorder NCT06060496 | Gopalkumar Rakesh | N/A |
| Recruiting | Amplification of Positivity for Alcohol Use NCT06030154 | Laureate Institute for Brain Research, Inc. | N/A |
| Completed | Craving Assessment in Patients With Alcohol Use Disorder Using Virtual Reality Exposure NCT05861843 | Charite University, Berlin, Germany | — |
| Completed | Decreasing the Temporal Window in Individuals With Alcohol Use Disorder NCT04128761 | Virginia Polytechnic Institute and State University | N/A |
| Recruiting | MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder NCT05709353 | University of Sydney | Phase 2 |
| Active Not Recruiting | TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study NCT06074341 | University of New Mexico | N/A |
| Recruiting | Mechanisms of Risky Alcohol Use in Young Adults: Linking Sleep to Reward- and Stress-Related Brain Function NCT05684094 | University of Oregon | N/A |
| Unknown | Supporting Women in the UK Armed Forces Who Consume Alcohol at an Increased Risk: Refining the DrinksRation Pl NCT05970484 | King's College London | N/A |
| Active Not Recruiting | Hyponatremia - Complications, Prognosis, Epidemiology in Finnish Tertiary Care NCT07430787 | University of Turku | — |
| Completed | Psilocybin-assisted Therapy for Treatment of Alcohol Use Disorder NCT05416229 | Anders Fink-Jensen, MD, DMSci | Phase 2 |
| Withdrawn | Ketamine for the Treatment for Alcohol Use Disorder in the ED NCT05661669 | Brigham and Women's Hospital | Phase 2 |
| Completed | Enhancing Prospective Thinking in Early Recovery (NERF) NCT06283446 | Indiana University | N/A |
| Unknown | Efficacy and Safety of Dual-target Deep Brain Stimulation for Treatment-resistant Alcohol Use Disorder NCT05884619 | Second Xiangya Hospital of Central South University | N/A |
| Completed | Metabolism in the Human Brain Following Consumption of a Keto-ester in Alcohol Use Disorder (AUD) With Proton NCT05937893 | Yale University | N/A |
| Active Not Recruiting | Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study NCT05885594 | University of Pennsylvania | EARLY_Phase 1 |
| Active Not Recruiting | Leveraging Virtual Care Strategies to Improve Access and Treatment for Individuals With Alcohol Use Disorders NCT05594238 | University of Michigan | N/A |
| Recruiting | Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Interventio NCT06005298 | Shirish S Barve | N/A |
| Active Not Recruiting | Utility of Brexanolone to Target Stress-induced Alcohol Use Among Men and Women With Posttraumatic Stress Diso NCT05223829 | Yale University | Phase 1 |
| Recruiting | StuDy AimED at Increasing AlCohol AbsTinEnce NCT05778734 | University of Illinois at Chicago | N/A |
| Unknown | Effects of Subconscious Memory Extinction in Patients With Alcohol Dependence and Its Mechanism NCT05942521 | Shenzhen Kangning Hospital | N/A |
| Unknown | Testing a Novel Therapeutic Strategy for Comorbid Post-Traumatic Stress Disorder and Alcohol Use Disorder NCT05692271 | Centre for Addiction and Mental Health | Phase 2 |
| Recruiting | Spironolactone in Alcohol Use Disorder (SAUD) NCT05807139 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Recruiting | Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study NCT05838274 | University of Texas at Austin | N/A |
| Recruiting | Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders NCT06434818 | Evon Medics LLC | Phase 2 |
| Completed | Semaglutide Therapy for Alcohol Reduction - Tulsa NCT05891587 | Oklahoma State University Center for Health Sciences | Phase 2 |
| Unknown | Efficacy and Safety of Dual-target DBS for Treatment-resistant Alcohol Use Disorder NCT05786872 | Shanghai Mental Health Center | N/A |
| Enrolling By Invitation | Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Interventio NCT05947539 | Arizona State University | N/A |
| Recruiting | Trial of a Culturally Informed Brief Intervention to Reduce Alcohol Related Health Disparities and Treatment I NCT05800899 | University of Texas, El Paso | N/A |
| Completed | Does Semaglutide Reduce Alcohol Intake in Patients With Alcohol Use Disorder and Comorbid Obesity? NCT05895643 | Psychiatric Centre Rigshospitalet | Phase 2 |
| Recruiting | Neural Correlates During Alcohol Intoxication NCT06118580 | Ohio State University | Phase 2 |
| Completed | Development and Effectiveness of an Alcohol Intervention Program for Adults Under Probation NCT06966180 | Mine Pazarcikci | N/A |
| Terminated | Project VALOR: Veteran Stress and Wellbeing NCT06095817 | Cornell University | N/A |
| Not Yet Recruiting | Virtual Reality Exposure Therapy in the Treatment of Alcohol Use Disorder NCT05841823 | Universiti Sains Malaysia | N/A |
| Completed | An Open-Label, Single Dose Study in Patients With Alcohol Use Disorder NCT05674929 | Beckley Psytech Limited | Phase 2 |
| Active Not Recruiting | Clinical Course of Alcohol Use Disorder Recovery NCT05607290 | University of South Florida | N/A |
| Recruiting | The Liver Care Trial NCT05855031 | Zealand University Hospital | N/A |
| Not Yet Recruiting | The Efficacy of Probiotics for the Treatment of Alcohol Use Disorder Among Adult Males NCT05830708 | Universiti Sains Malaysia | N/A |
| Recruiting | Alcohol Use Disorder and Cannabidiol NCT05613608 | University of Colorado, Denver | Phase 2 / Phase 3 |
| Recruiting | Semantic Networks in Alcohol Use Disorder Patients: Exploratory Study NCT05636033 | Institut National de la Santé Et de la Recherche Médicale, France | — |
| Completed | Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individ NCT05520190 | University of Rochester | N/A |
| Active Not Recruiting | Feasibility of Telephone-based Acceptance and Commitment Therapy in Hong Kong Chinese Young Adults With Alcoho NCT07501130 | The Hong Kong Polytechnic University | N/A |
| Withdrawn | Self Management and Recovery Training (SMART) Recovery Study NCT05756114 | Yale University | N/A |
| Withdrawn | Early Detection of Alcoholic Liver Disease NCT04070508 | University of Pittsburgh | — |
| Withdrawn | A Study of NAC for AUD NCT04964843 | Uniformed Services University of the Health Sciences | Phase 2 |
| Recruiting | Alcohol Research in HIV: Relapse Prevention NCT05163301 | Johns Hopkins University | N/A |
| Recruiting | Cannabis' Impact on Alcohol Consumption NCT05389930 | Brown University | Phase 2 |
| Recruiting | Brief Family Involved Treatment Telehealth NCT05674409 | Medical University of South Carolina | N/A |
| Recruiting | Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer NCT05505188 | University Hospital, Caen | N/A |
| Unknown | Effectiveness of a WeChat-based Alcohol Consumption Intervention Mini-program ("Sober Time ACT") in China NCT05827822 | Shanghai Mental Health Center | N/A |
| Recruiting | A Female-Specific CBT Group for Veteran Women With Alcohol Use Disorder in VA Primary Care Settings NCT06118346 | University of Massachusetts, Worcester | N/A |
| Completed | Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep NCT05458609 | Baylor College of Medicine | Phase 3 |
| Completed | Cytisine for Smoking Cessation NCT05729243 | Centre for Addiction and Mental Health | Phase 4 |
| Active Not Recruiting | EMA/EMI for Psychiatrically Hospitalized Emerging Adults Who Drink to Cope NCT05074030 | Butler Hospital | N/A |
| Recruiting | AAT for Alcohol Use Disorder in Veterans NCT05372029 | VA Office of Research and Development | N/A |
| Recruiting | Study of the Drivers of Late Diagnosis of Alcohol Related Diseases, Alone or in Combination With Metabolic Dys NCT06403332 | Hospital Universitari Vall d'Hebron Research Institute | N/A |
| Completed | ClientBot: a Conversational Agent That Supports Skills Practice and Feedback for Motivational Interviewing NCT05479890 | Lyssn.io, Inc. | N/A |
| Completed | Intensive Virtual Treatment With Remote Abstinence Monitoring for Alcohol Use Disorder NCT05722483 | Centre for Addiction and Mental Health | N/A |
| Completed | Phase 1b Study of DCR-AUD in Healthy Volunteers NCT05845398 | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | Phase 1 |
| Completed | Online Insomnia Intervention to Reduce Alcohol Use NCT05630118 | Jessica Weafer | N/A |
| Completed | Deep Brain Stimulation for Alcohol Use Disorder NCT05522751 | Khaled Moussawi | N/A |
| Completed | Integrated Digital Intervention for Alcohol Use Disorder NCT05748639 | Quit Genius | Phase 2 / Phase 3 |
| Recruiting | Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients NCT05365347 | Nova Scotia Health Authority | N/A |
| Completed | Orexin Receptor Antagonists as Modulators of Threat Sensitivity in Individuals With Alcohol Use Disorder NCT05656534 | Ohio State University | EARLY_Phase 1 |
| Recruiting | Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease NCT05548452 | Virginia Commonwealth University | Phase 1 / Phase 2 |
| Recruiting | Phenotyping Patients With Alcohol and Cannabis Use Disorders Using the Addictions Neuroclinical Assessment NCT05855668 | Centre for Addiction and Mental Health | N/A |
| Completed | Developing e-Covery, an App-based Intervention to Support Individuals With Co-occurring Problem Alcohol and Op NCT05325788 | Yale University | N/A |
| Enrolling By Invitation | Indigenous Recovery Planning for American Indians NCT05612061 | Montana State University | N/A |
| Completed | Multifamily Group Psychoeducation for SUD's in Turkey NCT05564559 | Ege University | N/A |
| Completed | Cannabidiol in Youth Alcohol Use Disorder NCT05317546 | Medical University of South Carolina | Phase 2 |
| Completed | Eye Movements Desensitization and Reprocessing Intervention in Preventing Craving in Alcohol Use Disorder NCT05606900 | Ege University | N/A |
| Completed | Online Relapse Prevention Therapy for Patients With Alcohol Use Disorder NCT05579210 | Dr. Nazanin Alavi | N/A |
| Recruiting | Promoting Alcohol Treatment Engagement Post-hospitalization NCT05338151 | Yale University | N/A |
| Active Not Recruiting | Long-term Recovery: Longitudinal Study of Neuro-behavioral Markers of Recovery and Precipitants of Relapse NCT04788004 | Virginia Polytechnic Institute and State University | — |
| Completed | Semaglutide for Alcohol Use Disorder NCT05520775 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Loneliness and Health Outcomes in the High Need Population NCT05484258 | Vanderbilt University Medical Center | N/A |
| Unknown | mHealth App for Changing Alcohol Use in Alaska Native American Indian People NCT05326438 | Southcentral Foundation | N/A |
| Recruiting | Donepezil and Cognitive Training for Alcohol Use Disorder (AUD) NCT05042102 | VA Connecticut Healthcare System | Phase 2 |
| Unknown | Contributing Factors of Solitary Drinking Among Adolescents and Young Adults NCT05337488 | The Hong Kong Polytechnic University | — |
| Recruiting | Improving Remote Breathalyzer Procedures Used by Clinicians and Researchers to Remotely Monitor Alcohol Use NCT05641389 | University of North Texas, Denton, TX | — |
| Completed | AAT-APP+: A Novel Brain-training App to Reduce Drinking NCT04923256 | Turning Point | N/A |
| Completed | Intranasal Oxytocin for the Treatment of Alcohol Use Disorder NCT03878316 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Unknown | The Efficacy of Robot-Assisted Intelligent Rehabilitation Treatment in Patients With AUD NCT05675553 | Shanghai Mental Health Center | N/A |
| Recruiting | LGG Supplementation in Patients With AUD and ALD NCT05178069 | University of Louisville | Phase 2 |
| Recruiting | Bright Light Therapy During Residential Alcohol Withdrawal NCT06878287 | Centre Hospitalier St Anne | N/A |
| Completed | Effects of Pioglitazone on Stress Reactivity and Alcohol Craving NCT05107765 | The University of Texas Health Science Center, Houston | Phase 1 / Phase 2 |
| Withdrawn | Targeting Stress-Induced Alcohol Relapse Risk With Doxazosin XL NCT03398252 | The University of Texas Health Science Center, Houston | Phase 1 |
| Completed | BioWare for AUD and PTSD NCT05187364 | Medical University of South Carolina | N/A |
| Completed | Non-invasive Vagal Nerve Stimulation in Alcohol Use Disorder NCT05226130 | VA Office of Research and Development | Phase 1 |
| Unknown | Psilocybin-Assisted Psychotherapy in Adults With Alcohol Use Disorder (AUD) NCT05646303 | Clairvoyant Therapeutics | Phase 2 |
| Completed | Novel Real-world Methods in Social Drinkers and AUD NCT05155176 | Yale University | — |
| Completed | Family-focused vs. Drinker-focused Smartphone Interventions to Reduce Drinking-related Consequences of COVID-1 NCT05419128 | University of Wisconsin, Madison | N/A |
| Completed | The Pitt Center for Emergency Responder Wellness NCT05357586 | University of Pittsburgh | N/A |
| Active Not Recruiting | A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users NCT04771650 | Boston University Charles River Campus | N/A |
| Unknown | Dexamethasone to Target Stress and Immune System Mechanisms Underlying Alcohol Craving NCT05305404 | Stony Brook University | EARLY_Phase 1 |
| Recruiting | Naltrexone in AUD Reward Drinkers NCT05028062 | University of Pennsylvania | Phase 4 |
| Recruiting | Tdcs And cogNitive traininG cOmbined for AUD (TANGO) NCT05062369 | University of Minnesota | N/A |
| Unknown | Bridging ED to Outpatient AUD Therapy With Naltrexone NCT05228418 | Albert Einstein Healthcare Network | Phase 4 |
| Withdrawn | In Hospital IM Naltrexone: A Pilot Study NCT05087771 | University of Colorado, Denver | Phase 4 |
| Completed | Biobehavioral Pathways Underlying Alcohol Use and Health NCT05135767 | Brown University | N/A |
| Completed | Effect of Endotoxin on Alcohol Consumption NCT04527185 | Yale University | Phase 2 |
| Completed | Reducing Stigma Among Healthcare Providers (RESHAPE-cRCT) NCT04282915 | George Washington University | N/A |
| Completed | Effectiveness of an Intervention in Patients With Excessive Alcohol Consumption NCT04811729 | Hospital Universitario Reina Sofia de Cordoba | N/A |
| Unknown | Internet-based A-CRA for Young Adults With Problematic Alcohol Use NCT04381533 | Nitya Jayaram-Lindstrom | N/A |
| Unknown | Cognitive Dysfunction in the Addictions Study - Project 4 (P4) NCT06299787 | Centre for Addiction and Mental Health | N/A |
| Active Not Recruiting | Coronavirus Disease 2019 (Covid-19) Impact on Alcohol-related Liver Disease Patient Outcomes, Care and Alcohol NCT05191446 | University of California, San Francisco | N/A |
| Active Not Recruiting | Alcoholic Liver Disease and the Gut Microbiome NCT05007470 | University of California, Los Angeles | N/A |
| Completed | Enhancing the Effects of Alcohol Treatment With Lamotrigine NCT04770493 | Brown University | Phase 2 |
| Terminated | Does Oxytocin Alter Tolerance to or Motivation for Alcohol NCT05312008 | Indiana University | Phase 2 |
| Recruiting | Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral NCT05117255 | University of Minnesota | N/A |
| Recruiting | Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis NCT05665179 | University of Michigan | N/A |
| Completed | Alcohol and Cannabis Concentrates Co-Administration NCT05999344 | University of Colorado, Denver | N/A |
| Completed | Human Laboratory Study of ASP8062 for Alcohol Use Disorder NCT05096117 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Oxytocin and Naltrexone: Investigation of Combined Effects on Stress- and Alcohol Cue-induced Craving in Alcoh NCT05093296 | Central Institute of Mental Health, Mannheim | Phase 2 / Phase 3 |
| Completed | Safety of Acamprosate in Treating Alcohol Use Disorder in the Post Liver Transplant Populations NCT06471686 | University of Southern California | Phase 2 |
| Withdrawn | MAP4343 Treatment for Alcohol Use Disorder NCT04157114 | The Scripps Research Institute | Phase 2 |
| Unknown | Riboflavin for Glutamate Reduction in Alcohol Withdrawal NCT04232800 | Oregon Health and Science University | Phase 2 |
| Withdrawn | Feasibility Trial of Pregnenolone for Posttraumatic Stress Disorder and Alcohol Use Disorder NCT04464148 | University of Texas Southwestern Medical Center | Phase 1 |
| Completed | Adverse Childhood Experiences in Alcohol Use Disorder NCT05048758 | Central Institute of Mental Health, Mannheim | — |
| Completed | Understanding Genetic Risk for Alcohol Use Disorder NCT05143073 | Virginia Commonwealth University | N/A |
| Completed | A Dialectical Behavioral Therapy Digital Health Solution for Outpatients Seeking Support for Substance Use NCT05094440 | Centre for Addiction and Mental Health | N/A |