Trials / Completed
CompletedNCT05107765
Effects of Pioglitazone on Stress Reactivity and Alcohol Craving
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 67 (actual)
- Sponsor
- The University of Texas Health Science Center, Houston · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to examine the effects of pioglitazone on stress-induced relapse risk in a laboratory model and to examine the effects of pioglitazone on drinking, stress/anxiety, and alcohol craving in the natural environment
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Pioglitazone | For the current trial we will follow recommended adult initial dosing at 30 mg/d to reach maintenance dose of 45 mg/d by end of week 1, which is within standard titration parameters as per the investigator's brochure. |
| DRUG | Placebo | Pill capsules will look same as that of active drug. |
Timeline
- Start date
- 2022-05-12
- Primary completion
- 2024-08-16
- Completion
- 2024-08-16
- First posted
- 2021-11-04
- Last updated
- 2025-08-27
- Results posted
- 2025-08-27
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT05107765. Inclusion in this directory is not an endorsement.