NCT03865615

Oxytocin on Approach Bias and Craving

The Effects of Intranasal Oxytocin on Approach Bias and Craving in Moderate to Heavy Alcohol Drinkers

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Jennifer Mitchell · Academic / Other
• Sex: All
• Age: 21 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This will be a laboratory-based investigation of the behavioral and neural effects of intranasal oxytocin on craving for alcohol and approach bias in moderate to heavy alcohol using subjects. This study uses a within-subject, randomized, placebo-controlled, counterbalanced, crossover design to compare the effects oxytocin and placebo. In this way, all subjects will be scanned twice; once following oxytocin administration and once following placebo administration, and will complete a series of behavioral tasks (both in and out of the scanner) at both visits.

Conditions

• Alcohol Use Disorder

Interventions

Type	Name	Description
DRUG	Oxytocin	intranasal oxytocin 40IU/mL
DRUG	Placebo	Placebo

Timeline

• Start date: 2023-11-01
• Primary completion: 2024-04-20
• Completion: 2024-04-20
• First posted: 2019-03-07
• Last updated: 2022-06-06

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study