Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07219966

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

A Phase 3, Multicenter, Randomized, Double-Blind Study to Investigate the Efficacy and Safety of Brenipatide Compared With Placebo for the Treatment of Adult Participants With Moderate-to-Severe Alcohol Use Disorder (RENEW-ALC-1)

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
1,100 (estimated)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with moderate-to-severe Alcohol Use Disorder (AUD). Participation in this study will last approximately 56 weeks.

Conditions

Interventions

TypeNameDescription
DRUGLY3537031Administered SC
DRUGPlaceboAdministered SC

Timeline

Start date
2025-10-15
Primary completion
2028-04-01
Completion
2028-04-01
First posted
2025-10-22
Last updated
2026-04-17

Locations

119 sites across 8 countries: United States, Belgium, China, Germany, Japan, South Korea, Taiwan, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT07219966. Inclusion in this directory is not an endorsement.