NCT05317546

Cannabidiol in Youth Alcohol Use Disorder

Neurobehavioral Effects of Cannabidiol in Youth Alcohol Use Disorder

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 16 Years – 22 Years
• Healthy volunteers: Accepted

Summary

The goal of this study is to test cannabidiol (CBD) as a potentially effective candidate medication for youth alcohol use disorder (AUD). To accomplish this goal, this study will use a randomized, double-blind, within-subjects crossover design. In counterbalanced order, 50 youth (ages 16-22) will receive 600 mg of CBD or placebo three hours before a neuroimaging and behavioral assessment paradigm. The total amount of time the participant will be in the study is approximately one month.

Conditions

• Alcohol Use Disorder

Interventions

Type	Name	Description
DRUG	Cannabidiol	In counterbalanced order, 50 youth (ages 16-22) will receive 600mg of cannabidiol or placebo three hours before a neuroimaging and behavioral assessment paradigm, separated by an approximate 18-day washout period.

Timeline

• Start date: 2022-10-01
• Primary completion: 2024-06-25
• Completion: 2024-06-25
• First posted: 2022-04-08
• Last updated: 2025-08-14
• Results posted: 2025-08-14

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study