NCT07510113

Probiotic Study in Alcohol Recovery

Effects of Probiotic Supplementation in Alcohol Use Disorder: A Randomised, Placebo-Controlled Pilot Trial

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 38 (estimated)
• Sponsor: Loughborough University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Alcohol Use Disorder (AUD) is a common condition that can affect physical and mental health. Current treatments do not work for everyone, and new approaches are needed. This study is investigating whether taking a probiotic supplement (a type of "good bacteria") can help reduce alcohol craving and improve psychological, biological, and cognitive wellbeing. Participants are randomly assigned to receive either a probiotic supplement or a placebo (a capsule with no active ingredients) for four weeks. Neither the participants nor the researchers know which treatment is given during the study. The study measures alcohol craving, gastrointestinal composition, thinking and memory, mental health, and eating and drinking behaviour at the start and end of the study. The aim is to understand whether probiotics could be a helpful additional approach to support people with AUD.

Conditions

• Alcohol Use Disorder

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic Formula Capsule	A probiotic or placebo is randomly administered to patients with alcohol use disorder

Timeline

• Start date: 2025-12-15
• Primary completion: 2026-04-17
• Completion: 2026-04-17
• First posted: 2026-04-03
• Last updated: 2026-04-03

Locations

1 site across 1 country: United Kingdom