NCT05861843

Craving Assessment in Patients With Alcohol Use Disorder Using Virtual Reality Exposure

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 61 (actual)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Alcohol use disorder (AUD) is a burdensome clinical disorder with high relapse rates. Virtual Reality (VR)-based therapeutic and diagnostic approaches have received increasing attention in the treatment of AUD but evidence on the induction of craving via VR scenarios is still needed. Craving for alcohol is associated with psychological and physiological responses. This single-arm clinical study will be conducted including n=60 patients with AUD. Using a head-mounted display (HMD), patients will be confronted with three different VR scenarios (neutral vs. two target situations) while heart rate, heart rate variability (HRV), pupillometry and electrodermal activity (EDA) will be measured continuously. Subjective craving levels will be assessed pre-/during/post-exposure to each VR scenario.

Conditions

• Alcohol Use Disorder

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Virtual Reality-based cue exposure paradigm	Virtual Reality (VR) cue exposure to alcohol-associated cues using head-mounted displays (HMD)

Timeline

• Start date: 2023-09-23
• Primary completion: 2024-06-30
• Completion: 2024-06-30
• First posted: 2023-05-17
• Last updated: 2024-08-26

Locations

1 site across 1 country: Germany