| Not Yet Recruiting | Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain Intractable Pain, Palliative Care | Phase 1 / Phase 2 | 2026-04-27 |
| Not Yet Recruiting | Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Progressive Multifocal Leukoencephalopathy | Phase 2 | 2026-04-22 |
| Not Yet Recruiting | Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2 (PD1-PASC Post-Acute COVID-19 Syndrome | Phase 1 | 2026-04-22 |
| Recruiting | Predicting Future Errors During Skill Performance Healthy | — | 2026-04-22 |
| Recruiting | Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Strok Stroke, Brain Disease, Vascular Diseases | — | 2026-04-22 |
| Recruiting | Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques Tics, Functional Tics | — | 2026-04-22 |
| Not Yet Recruiting | Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma Recurrent Glioblastoma, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype, Relapsed Cancer | Phase 1 / Phase 2 | 2026-04-22 |
| Recruiting | DDAVP for Pituitary Adenoma Cushing's Disease, Pituitary Adenoma | N/A | 2026-03-09 |
| Active Not Recruiting | Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS) Amyotrophic Lateral Sclerosis, Motor Neuron Disease | Phase 1 | 2026-02-02 |
| Recruiting | A Prospective Natural History and Outcome Measure Validation Study of Congenital Myasthenic Syndromes Myasthenic Syndromes, Congenital | — | 2025-05-12 |
| Withdrawn | Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing s Disease Cushing's Disease | Phase 2 | 2025-04-11 |
| Recruiting | Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort Fatigue Syndrome, Chronic | EARLY_Phase 1 | 2025-04-09 |
| Recruiting | Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection PASC Post Acute Sequelae of COVID-19 | — | 2025-03-27 |
| Completed | Long-Term Neurologic and Neurocognitive Sequelae Following Pediatric Ebola Virus in Liberia Ebola, Post-Acute Ebola Syndrome | — | 2025-02-14 |
| Recruiting | Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Ep Epilepsy | Phase 1 | 2024-11-19 |
| Recruiting | Data Collection of Standard Care of Patients in the EMG Section Neuropathy, Muscle Disorders, Dysautonomia | — | 2024-06-24 |
| Recruiting | Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology Nervous System Diseases (C10 Unique ID D009422) | — | 2024-03-26 |
| Recruiting | Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Multiple Sclerosis, Progressive Multifocal Leukoencephalopathy | Phase 1 | 2023-10-19 |
| Enrolling By Invitation | Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 Systemic Inflammation, Neuroinflammation, Microvascular Thrombosis | Phase 2 | 2023-07-10 |
| Recruiting | NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH) Gulf War Illness | — | 2023-04-16 |
| Recruiting | Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects Normal Physiology | — | 2023-02-02 |
| Recruiting | Natural History Protocol for Movement Disorders Movement Disorder, Tremor, Parkinson's Disease | — | 2022-10-17 |
| Active Not Recruiting | Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Functional Movement Disorder | Phase 2 | 2022-05-06 |
| Recruiting | Investigational Use of Neuromuscular Ultrasound Muscular Dystrophy, Peripheral Neuropathy, Motor Neuron Disorder | — | 2022-04-18 |
| Recruiting | Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health Post-Coronavirus Disease 19 | — | 2022-01-02 |
| Withdrawn | Attentional Performance in Parkinson Disease Parkinson's Disease | — | 2021-12-06 |
| Completed | Procedural Motor Memory in Long COVID-19 Infectious Metabolic Encephalopathy, Ischemic Stroke, Seizure | — | 2021-11-15 |
| Recruiting | Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA) Spinal and Bulbar Muscular Atrophy, Kennedys Disease, Motor Neuron Disease | — | 2021-10-25 |
| Recruiting | Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis HAM/TSP | Phase 1 / Phase 2 | 2021-09-24 |
| Completed | Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory Normal Physiology | N/A | 2021-07-09 |
| Withdrawn | Technical Development of Clinical Laboratory Studies Healthy Volunteers | — | 2021-05-25 |
| Completed | NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patien Progressive Multifocal Leukoencephalopathy | EARLY_Phase 1 | 2021-05-05 |
| Completed | Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex Normal Physiology | — | 2021-04-21 |
| Active Not Recruiting | Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed Multiple Sclerosis | Phase 2 | 2021-04-15 |
| Recruiting | The Beneficial Effects of Naps on Motor Learning Stroke | — | 2021-03-04 |
| Completed | Acute Effects of Medium Chain Triglyceride (MCT) Nutritional Ketosis on Parkinson's Disease (PD) Symptoms and Parkinson's Disease | Phase 1 | 2021-01-21 |
| Completed | Study of Volition: Behavioral Analysis and Clinical Neurophysiological Analysis Normal Physiology | N/A | 2020-12-22 |
| Recruiting | Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurologica Amyotrophic Lateral Sclerosis Type 4, Inherited Neurological Disorders of RNA Processing | — | 2020-12-14 |
| Completed | Clinical Correlates of COVID-19 Pandemic in Patients With Functional Movement Disorder (FMD) and Parkinson's D Parkinson's Disease, Functional Movement Disorders, COVID-19 | — | 2020-10-29 |
| Completed | An Observational Study of Neurologic Function After COVID-19 Infection COVID-19 | — | 2020-10-28 |
| Terminated | Assessing Clinical Endpoints and Biomarkers in Myotonic Dystrophy Type-1 and Type 2 (ASCEND-DM) Myotonic Dystrophy Type-1, Myotonic Dystrophy Type-2 | — | 2020-02-24 |
| Completed | Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple Sclerosis Multiple Sclerosis | Phase 1 / Phase 2 | 2019-10-25 |
| Completed | Modulating the Hippocampal and Striatal Memory Networks With rTMS Normal Behavioral Patterns | N/A | 2019-09-26 |
| Recruiting | Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery Pituitary Neoplasm | N/A | 2019-05-09 |
| Completed | HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS) Amyotrophic Lateral Sclerosis | Phase 1 | 2019-04-01 |
| Completed | Exploring the Relationship Between Brain Asymmetry and Attention Normal Physiology | N/A | 2019-02-28 |
| Withdrawn | Modulation of the Parieto-frontal Communication Normal Physiology | N/A | 2019-02-03 |
| Completed | Large-Scale Online Studies of Early Motor Skill Learning Healthy | — | 2019-01-09 |
| Completed | Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade Glioblastoma | Phase 1 | 2018-09-24 |
| Recruiting | Influence of Brain Oscillation-Dependent TMS on Motor Function Healthy, Stroke, Normal Physiology | — | 2018-09-11 |
| Active Not Recruiting | Clinical Laboratory Evaluation of Chronic Autonomic Failure Parkinson's Disease, Multiple System Atrophy, Autonomic Failure | — | 2018-09-06 |
| Completed | Blood-Brain Barrier Disruption in People With White Matter Hyperintensities Who Have Had a Stroke Cerebrovascular Disorder, Stroke, Aging | — | 2018-09-06 |
| Completed | PD-1 Inhibition to Determine CNS Reservoir of HIV-Infection HIV Infections | Phase 1 | 2018-04-09 |
| Completed | Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in People With Functio Movement Disorders | — | 2018-03-29 |
| Recruiting | Investigating Epilepsy: Screening and Evaluation Seizures, Epilepsy, Epilepsy, Temporal Lobe | — | 2018-03-28 |
| Withdrawn | Gait Disorders in Parkinson's Disease Parkinson's Disease | EARLY_Phase 1 | 2018-01-24 |
| Active Not Recruiting | Deep Brain Stimulation Surgery for Focal Hand Dystonia Dystonia, Focal Dystonia, Musician's Dystonia | Phase 1 / Phase 2 | 2018-01-17 |
| Completed | Pathophysiology of Focal Hand Dystonia Dystonia | N/A | 2017-12-12 |
| Terminated | Photic Blink Reflex in People With Blepharospasm and Increased Blinking Blepharospasm | — | 2017-10-30 |
| Recruiting | Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Frontotemporal Dementia, Amyotrophic Lateral Sclerosis, Progressive Supranuclear Palsy | — | 2017-10-11 |
| Completed | Chart Review: Central Motor Conduction Time in Neurological Disorders Neurological Disorder | — | 2017-10-04 |
| Completed | Measuring the Latency Connectome in the Central Nervous Systems Using Neuroimaging and Neurophysiological Tech Healthy Volunteers | — | 2017-10-02 |
| Terminated | Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease? Parkinson Disease, Cerebrospinal Fluid | Phase 1 | 2017-09-25 |
| Terminated | Loss of Depotentiation in Focal Dystonia Focal Dystonia, Healthy Volunteers | — | 2017-09-20 |
| Withdrawn | Interhemispheric Interaction of Parieto-Motor Cortico-Cortical Plasticity Healthy Volunteers | — | 2017-08-11 |
| Completed | Clinical and Physiological Studies of Tremor Syndromes Parkinson Disease, Dystonia, Essential Tremor | — | 2017-05-05 |
| Completed | Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor Essential Tremor, Cervical Dystonia, Focal Dystonia | — | 2017-04-07 |
| Completed | Functional Connectivity as a Biomarker of rTMS Traumatic Brain Injury | Phase 1 / Phase 2 | 2017-03-24 |
| Completed | Neurophysiology of Surround Inhibition in the Human Motor Cortex Normal Physiology | — | 2017-02-07 |
| Completed | Cholinergic Receptor Imaging in Dystonia Cervical Dystonia, Dystonia, Movement Disorder | — | 2016-12-16 |
| Terminated | Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31 Hereditary Spastic Paraplegia | — | 2016-11-18 |
| Completed | Effects of Prism Adaption and rTMS on Brain Connectivity and Visual Representation Normal Physiology, Stroke | — | 2016-11-04 |
| Enrolling By Invitation | Study of Direct Brain Recording and Stimulation for Memory Enhancement Epilepsy | — | 2016-10-28 |
| Completed | Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health Chronic Fatigue Syndrome | N/A | 2016-10-10 |
| Recruiting | Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques Multiple Sclerosis | Phase 2 | 2016-10-05 |
| Recruiting | Pathological Basis of MRI Signal Changes in Multiple Sclerosis Multiple Sclerosis | — | 2016-04-07 |
| Completed | Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy With Ex Vivo Generated Polyomav Progressive Multifocal Leukoencephalopathy | EARLY_Phase 1 | 2016-03-28 |
| Recruiting | Tumor Related Epilepsy Epilepsy, Cancer, Brain Neoplasm | — | 2016-01-26 |
| Recruiting | Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli Normal Physiology | — | 2016-01-14 |
| Completed | In Vivo Characterization of Inflammation With Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanopart Multiple Sclerosis | Phase 1 | 2015-11-27 |
| Completed | Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal Hi Writer's Cramp, Healthy Volunteers, Cervical Dystonia | EARLY_Phase 1 | 2015-08-20 |
| Terminated | Anakinra, A Recombinant Human IL-1 Receptor Antagonist for Neuroinflammation in HIV-1 Infection HIV Infections, Neurologic Disorders | Phase 1 | 2015-08-17 |
| Completed | Natural History of Multiple Sclerosis and Its Mimickers Neurologic Disorders, Healthy Volunteers, Multiple Sclerosis | — | 2015-07-23 |
| Recruiting | Inflammatory and Infectious Diseases of the Nervous System Brain Disease | — | 2015-05-06 |
| Active Not Recruiting | Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal Neuropathy Giant Axonal Neuropathy, Gene Transfer | Phase 1 | 2015-04-24 |
| Terminated | Oral Guanabenz for Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis | Phase 1 | 2015-04-21 |
| Completed | Muscle Ultrasound Measures as Biomarkers of Upper Motor Neuron Function Muscle Spasticity | — | 2015-03-25 |
| Withdrawn | Feasibility Study of Deep Brain Recordings for Learning and Memory Movement Disorders | — | 2015-03-23 |
| Withdrawn | Physiological and Psychosomatic Effects of Exposure to MRI Scanning Environment Healthy Volunteers | — | 2014-12-23 |
| Completed | Neural Basis of Decision-Making Deficits in Traumatic Brain Injury Traumatic Brain Injury | Phase 1 | 2014-11-18 |
| Withdrawn | Effect of Recombinant Erythropoietin on Numbers of Circulating Endothelial Progenitor Cells in People With Per Traumatic Brain Injury | Phase 2 | 2014-08-15 |
| Completed | Study of Hepatic Function in Patients With Spinal and Bulbar Muscular Atrophy Spinal and Bulbar Muscular Atrophy (SBMA), Motor Neuron Disease | — | 2014-08-04 |
| Completed | Botulinum Toxin for Pelvic Pain in Women With Endometriosis Endometriosis, Chronic Pelvic Pain, Pelvic Muscle Spasm | Phase 1 / Phase 2 | 2014-07-30 |
| Completed | Efficacy of Levetiracetam in Oromandibular and Cranial Dystonia Oromandibular Dystonia, Cranial Dystonia | Phase 2 | 2014-07-01 |
| Terminated | Clinical Autonomic Disorders: A Training Protocol Posttraumatic Stress Disorder, Pseudopheochromocytoma, Healthy Volunteers | — | 2014-06-05 |
| Completed | Effect of Vorinostat on Nervous System Hemangioblastomas in Von Hippel-Lindau Disease (Missense Mutation Only) Von Hippel-Lindau Disease | Phase 1 | 2014-04-05 |
| Recruiting | Deep Brain Stimulation Therapy in Movement Disorders Parkinson's Disease | N/A | 2014-04-02 |
| Completed | Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency Metabolic Disease, Seizures | Phase 2 | 2014-03-31 |
| Terminated | fMRI Neurofeedback for Motor Rehabilitation Stroke, fMRI | — | 2014-03-12 |
| Recruiting | Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging D Epilepsy | — | 2014-03-11 |
| Terminated | Depotentiation in People With Focal Hand Dystonia Focal Dystonia, Healthy Volunteers | — | 2014-03-05 |
| Completed | Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp Dystonia | Phase 1 / Phase 2 | 2013-12-03 |
| Completed | Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions Healthy Volunteers | — | 2013-10-26 |
| Completed | Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People With Multiple Sclerosis Multiple Sclerosis | Phase 1 | 2013-10-17 |
| Completed | Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9OR Amyotrophic Lateral Sclerosis, Frontotemporal Lobar Degeneration | — | 2013-09-30 |
| Completed | Raltegravir for HAM/TSP HTLV-I Infection | EARLY_Phase 1 | 2013-09-05 |
| Terminated | Effects of Exercise on Memory in Healthy and Brain-Injured Individuals Traumatic Brain Injury | Phase 1 | 2013-08-31 |
| Terminated | Cerebrospinal Fluid Collection and Repository Storage Nervous System Diseases | — | 2013-07-29 |
| Recruiting | Thinking and Memory Problems in People With HIV HIV Positive | — | 2013-07-08 |
| Recruiting | Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers Neuromuscular Disease, Motor Neuron Disease, Inherited Neuromuscular Conditions | N/A | 2013-06-20 |
| Terminated | A Study of Movement Disorders Using the QMAT At-Home Testing Device Movement Disorders, Parkinson's Disease | — | 2013-06-18 |
| Completed | The Effects of Repetitive Paired Associative Stimulation in Dystonia Dystonia | — | 2013-06-18 |
| Completed | Exercise Education for Adults With Seizure Disorders Seizures, Epilepsy | EARLY_Phase 1 | 2013-05-10 |
| Completed | Imaging Studies of Cognitive Impairment in Parkinson s Disease Parkinson Disease, Dementia | — | 2013-04-04 |
| Terminated | Natural History of Optic Neuritis Multiple Sclerosis | — | 2013-03-20 |
| Completed | AAV2-GDNF for Advanced Parkinson s Disease Parkinson's Disease | Phase 1 | 2013-03-13 |
| Terminated | Transcranial Magnetic Stimulation for Focal Hand Dystonia Dystonia | — | 2013-02-13 |
| Completed | Treatment of Functional Movement Disorders With Psychotherapy Movement Disorders | N/A | 2012-12-11 |
| Withdrawn | Deep Brain Stimulation for Refractory Alcoholism Alcoholism | Phase 1 | 2012-11-30 |
| Completed | Effects of Transcranial Magnetic Stimulation on Object Recognition Repetitive TMS (rTMS), Sham rTMS, Bilateral rTMS | N/A | 2012-11-16 |
| Recruiting | Natural History Study of Progressive Multifocal Leukoencephalopathy (PML) Progressive Multifocal Leukoencephalopathy | — | 2012-11-08 |
| Terminated | Acetyl Hexapeptide-8 for Blepharospasm Focal Dystonia | Phase 2 | 2012-11-01 |
| Completed | Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility Multiple Sclerosis | — | 2012-08-15 |
| Completed | Brain P-gp and Inflammation in People With Epilepsy Epilepsies, Partial | — | 2012-07-31 |
| Completed | The Effects of Chronic Exposure to Low-Level Blasts Tramatic Brain Injury | — | 2012-07-30 |
| Completed | Taurine Therapy for SSADH Deficiency Succinic Semialdehyde Dehydrogenase | — | 2012-04-27 |
| Completed | Validating a New Writer s Cramp Scale Dystonia | — | 2012-03-21 |
| Recruiting | Genetic and Physical Study of Childhood Nerve and Muscle Disorders Muscular Dystrophies, Muscle Myopathies, Hereditary Spastic Paraplegias | — | 2012-03-20 |
| Terminated | Infants With Spinal Muscular Atrophy Type I Spinal Muscular Atrophy | — | 2012-02-07 |
| Completed | Studying Motor Neuron Tests Healthy Subjects, Magnetic Resonance Imaging, Central Nervous System | — | 2012-02-01 |
| Completed | Imaging Biomarkers in Parkinson s Disease Parkinson Disease | — | 2012-01-24 |
| Completed | Service Member Fatigue and Lack of Motivation Following Concussion Fatigue, Traumatic Brain Injury | — | 2011-12-01 |
| Terminated | Buspirone Therapy for Localized Epilepsy Anxiety Disorder, Seizures, Epilepsy | Phase 2 | 2011-11-22 |
| Withdrawn | Combined Deep Brain Stimulation for Parkinson's Disease Parkinson Disease | Phase 1 / Phase 2 | 2011-11-08 |
| Completed | Octanoic Acid for Essential Tremor Essential Tremor | Phase 1 | 2011-10-28 |
| Completed | Effects of Hormone Stimulation on Brain Scans for Cushing s Disease Pituitary Neoplasm | EARLY_Phase 1 | 2011-10-11 |
| Completed | Studying Skeletal Muscle, Heart, and Diaphragm Imaging in Boys With Duchenne Muscular Dystrophy Muscular Dystrophy, Muscular Disease | — | 2011-09-15 |
| Recruiting | Deep Brain Stimulation Surgery for Movement Disorders Parkinson's Disease, Essential Tremor, Dystonia | N/A | 2011-08-17 |
| Withdrawn | Bevacizumab With or Without Surgery for Adult Glioblastomas Glioblastoma, Brain Neoplasm | Phase 2 | 2011-07-15 |
| Completed | Effect of Functional Exercise in Patients With Spinal Bulbar Muscular Atrophy Motor Neuron Disease | Phase 1 / Phase 2 | 2011-06-08 |
| Terminated | Brain Areas Involved in Sound and Spoken Word Memory Brain Mapping, Language Disorder, Adult | — | 2011-05-26 |
| Withdrawn | Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resist Obsessive-Complusive Disorder | — | 2011-05-26 |
| Recruiting | Surgery as a Treatment for Medically Intractable Epilepsy Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy | — | 2011-03-21 |
| Completed | Structural and Functional Neuroimaging Studies of Combat Veterans Traumatic Brain Injury, PTSD | — | 2011-01-26 |
| Terminated | PRX-00023 Therapy in Localization-Related Epilepsy Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy | Phase 2 | 2011-01-07 |
| Completed | Intravenous Norepinephrine for Orthostatic Hypotension Orthostatic Hypertension | Phase 1 / Phase 2 | 2011-01-01 |
| Terminated | The Effect of Transcranial Magnetic Stimulation on Learning With Reward in Healthy Humans Normal Physiology, fMRI | — | 2010-12-07 |
| Completed | Evaluation, Pathogenesis, and Outcome of Subjects With or Suspected Traumatic Brain Injury Traumatic Brain Injury | — | 2010-10-07 |
| Completed | Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients Neoplasms, Nervous System Disease, Vestibular Disease | — | 2010-09-22 |
| Terminated | Double Blind Combination of Rituximab by Intravenous and Intrathecal Injection Versus Placebo in Patients With Multiple Sclerosis | Phase 1 / Phase 2 | 2010-09-01 |
| Completed | Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates Essential Tremor | — | 2010-08-30 |
| Withdrawn | Facilitating Numerical Processing With Transcranial Stimulation in Developmental Dyscalculia Cognition Disorder, Brain Mapping | — | 2010-08-17 |
| Completed | Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury Traumatic Brain Injury, Stroke, Headache | — | 2010-08-10 |
| Active Not Recruiting | A Prospective Natural History Study of Patients With Syringomyelia Syringomyelia, Arnold Chiari Deformity | — | 2010-08-03 |
| Withdrawn | Physiology of Volition Studied With Nerve Block Healthy Volunteers | — | 2010-06-01 |
| Completed | Investigating Mechanism of Action of DAC HYP in the Treatment of High-Inflammatory Multiple Sclerosis (MS) Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting | Phase 1 | 2010-05-13 |
| Completed | Oxidative Stress in Motor Neuron Disease: COSMOS Add-On Study Motor Neuron Disease, Primary Lateral Sclerosis | — | 2010-05-13 |
| Terminated | Genetics of Motor Learning Parkinson s Disease, Dystonic Disorders, Focal Dystonia | — | 2010-04-14 |
| Completed | The Influence of Sensory Stimuli on Gait Imagery in Patients With Freezing of Gait Parkinson Disease | — | 2010-02-01 |
| Completed | SMN Copy Number Distribution in Mali, West Africa Spinal Muscular Atrophy | — | 2010-01-21 |
| Completed | Screening Protocol for Patients With Stroke Chronic Stroke | — | 2010-01-05 |
| Completed | Physiological Investigations of Movement Disorders Parkinson's Disease, Tourette's Syndrome, Tic Disorders | N/A | 2009-12-08 |
| Completed | Cerebral Activity Related to Primary Motor Stereotypies in Children: An EEG Study. Movement Disorder | — | 2009-12-02 |
| Terminated | Recording and Modulation of Neuronal Mechanisms During Operant Conditioning: a MEG Study Central Nervous System | — | 2009-10-22 |
| Completed | 50 Hz Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Parkinson's Disease Parkinson Disease | Phase 1 / Phase 2 | 2009-09-01 |
| Completed | High-Density Direct Current Brain Polarization Healthy Volunteer, HV | Phase 1 | 2009-07-20 |
| Completed | A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm Focal Dystonia | Phase 1 / Phase 2 | 2009-07-01 |
| Completed | GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression Epilepsy, Epilepsy, Temporal Lobe, Depression | — | 2009-06-29 |
| Withdrawn | Convection-Enhanced Delivery to Study the Pathophysiology Underlying the Clinical Features of Parkinson s Dise Parkinson's Disease | Phase 1 | 2009-06-02 |
| Completed | Biomarkers of Risk of Parkinson Disease Parkinson Disease, Autonomic Nervous System Diseases, Pure Autonomic Failure | — | 2009-05-27 |
| Completed | Changes in the Posterior Parietal Cortex - Primary Motor Cortex Pathway Induced by Motor Training Movement Disorders, Heathly Subjects | — | 2009-05-14 |
| Terminated | Investigation of Neurofeedback With Real-Time fMRI in Healthy Volunteers and Patients With Hyperkinetic Moveme Movement Disorder, Tourette Syndrome, Healthy Volunteer | — | 2009-04-17 |
| Completed | Effect of Reward on Learning in Motor Cortex Healthy | — | 2009-04-15 |
| Completed | Magnetoencephalography in Absence Seizures Seizures | — | 2009-04-15 |
| Terminated | An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Pr Brain Neoplasm, Glioma | Phase 1 | 2009-04-07 |
| Completed | Exploring a Motor Learning Technique Based on the Mirror Motor Neuron System Healthy | — | 2009-03-25 |
| Completed | Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor Essential Tremor | Phase 1 / Phase 2 | 2009-02-01 |
| Completed | Using Transcranial Direct Current Stimulation (tDCS) to Enhance the Benefit of Movement Training in Stoke Pati Stroke | N/A | 2008-10-29 |
| Completed | Role of the Sensory Experience in Generating Motor Tics in Tourette Syndrome Tic Disorder, Tourette Syndrome | — | 2008-09-15 |
| Terminated | Warfighter Head Injury Study Head Injury | — | 2008-09-05 |
| Completed | Brain Activity During Strategic Planning Healthy Volunteers | — | 2008-08-01 |
| Completed | Brain Activity in Time Discrimination and Sensory Input Healthy Volunteers | — | 2008-07-28 |
| Completed | Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia Spasmodic Dysphonia, Focal Dystonia | — | 2008-07-09 |
| Completed | Language Mapping in Patients With Epilepsy Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy | — | 2008-06-13 |
| Completed | Autoimmunity in Neurologic Complications of Celiac Disease Ataxia | — | 2008-06-02 |
| Completed | Lithium Treatment for Patients With Spinocerebellar Ataxia Type I Spinocerebellar Ataxia Type I | Phase 1 | 2008-05-18 |
| Recruiting | Natural History Study of Patients With Neurofibromatosis Type 2 Neurofibromatosis | — | 2008-03-21 |
| Completed | Aneurysms and Carotid Artery Block in Newborns Cerebrovascular Disorder | — | 2008-03-17 |
| Terminated | Relationship of HHV-6B Virus to Seizures and Brain Injury Epilepsy, HHV6B Infection | — | 2008-01-03 |
| Completed | Association Between Focal Dystonia and Complex Regional Pain Syndrome Focal Dystonia, Peripheral Nervous System Disease | — | 2007-12-21 |
| Completed | Motor Cortex Reward Signaling in Parkinson Disease Parkinson Disease | — | 2007-11-08 |
| Completed | Neurobiology of Functional Movement Disorder and Non-Epileptic Seizures Movement Disorders | EARLY_Phase 1 | 2007-10-05 |
| Terminated | Augmenting Effects of L-DOPS With Carbidopa and Entacapone Parkinson Disease, Multiple System Atrophy, Autonomic Nervous System Diseases | Phase 1 / Phase 2 | 2007-10-01 |
| Completed | Brain Changes in Blepharospasm Blepharospasm | — | 2007-07-09 |
| Completed | Brain Function in Performance of Motor Tasks Brain Connectivity | — | 2007-07-03 |
| Terminated | Brain Changes in Blepharospasm Dystonia, Focal Dystonia, Cerebellar Disease | — | 2007-06-12 |
| Completed | Movement of Epiglottis During Swallowing Deglutition, Dysphagia | — | 2007-05-16 |
| Completed | Influence of Area of Brain Damage on Brain Reorganization After Chronic Stroke Central Nervous System Disease, Cerebrovascular Accident, Stroke | — | 2007-05-14 |
| Completed | Effect of Electrical Stimulation (DC Polarization) to the Brain on Memory Healthy | Phase 1 / Phase 2 | 2007-05-01 |
| Completed | Botulinum Toxin to Treat Restless Legs Syndrome Restless Legs Syndrome | Phase 1 / Phase 2 | 2007-05-01 |
| Completed | Measuring Blood Flow in the Brain Traumatic Brain Injury, Healthy | — | 2007-04-24 |
| Terminated | Characteristics of Parkinson s Disease Associated With the LRRK-2 Gene Mutation Parkinson Disease | — | 2007-04-23 |
| Completed | A Study to Evaluate and Characterize the Effect of Pharmacological Chemicals on Blood From Patients With Gauch Gaucher Disease | — | 2007-04-19 |
| Completed | Brain Activity in People With Functional Movement Disorders Functional Movement Disorders | — | 2007-03-08 |
| Terminated | The Role of Serotonin in Seizures Epilepsy, Seizures | — | 2007-02-20 |
| Completed | Brain Peripheral Benzodiazepine Receptors in Patients With Multiple Sclerosis Multiple Sclerosis | Phase 1 | 2007-02-05 |
| Completed | Sequence Effect in Parkinson's Disease Parkinson's Disease | — | 2007-02-01 |
| Completed | Spaced Versus Massed Skill Learning Healthy Volunteer | — | 2007-01-17 |
| Completed | Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System Motor Function of Healthy Physiology | EARLY_Phase 1 | 2007-01-14 |
| Completed | Direct Current Brain Polarization of the Frontal Lobes Healthy | Phase 1 | 2007-01-11 |
| Completed | Detecting a Reward Signal in the Motor Cortex Healthy | — | 2007-01-08 |
| Completed | Effects of tDCS Over the Cerebellum on Motor Function Healthy | — | 2006-12-14 |
| Completed | MRI of Alzheimer's Disease Imaging Amyloid Plaques in Persons With and Without Memory Problems Alzheimer's Disease | — | 2006-12-14 |
| Completed | Enhancing Brain Activity With Magnetic Stimulation Healthy | — | 2006-11-03 |
| Completed | Motor Skill Learning in People With Parkinson's Disease Parkinson's Disease | — | 2006-11-02 |
| Completed | Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis Multiple Sclerosis | — | 2006-10-26 |
| Completed | Enhancing Motor Task Training by Action Observation Watching Others Perform the Task Motor Memory | — | 2006-10-18 |
| Completed | Brain Connectivity Between Visual Input and Movement Occipital Cortex, Prefrontal Cortex, Healthy | — | 2006-09-12 |
| Completed | Muscle Contraction in Patients With Focal Hand Dystonia Focal Hand Dystonia | — | 2006-09-11 |
| Completed | Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS) Stroke, Cognitive Symptoms | — | 2006-09-09 |
| Completed | Hypersensitivity in Tourette Syndrome Tourette's Syndrome | — | 2006-08-21 |
| Completed | Influence of Theta Burst Stimulation and Carbidopa-Levodopa on Motor Performance in Stroke Patients Stroke | — | 2006-08-08 |
| Completed | Collection of Blood Samples for DNA in Motor Neuron Disease Motor Neuron Diseases | — | 2006-08-07 |
| Completed | Plasma Exchange for Autoimmune Autonomic Failure Plasma Exchange, Autonomic Failure | — | 2006-07-14 |
| Completed | A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Chronic Dysphagia, Multiple Sclerosis, Parkinson Disease | Phase 2 | 2006-07-01 |
| Completed | Brain Stimulation to Treat Blepharospasm or Meige Syndrome Blepharospasm, Focal Dystonia | Phase 2 | 2006-06-22 |
| Completed | Electrical Brain Stimulation to Reduce Epileptic Seizures Temporal Lobe Epilepsy | — | 2006-06-19 |
| Completed | Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis Cerebral Cortex Dysfunction | — | 2006-06-06 |
| Completed | Gait Training and Brain Changes in Stroke Patients Gait Training, Locomotion | — | 2006-06-02 |
| Completed | Improving Hand Movement Training Through Electrical Stimulation of the Brain Metaplasticity | — | 2006-05-24 |
| Completed | Long-Term Motor Learning in Focal Hand Dystonia Focal Hand Dystonia | — | 2006-05-09 |
| Completed | Plasticity in Cervical Dystonia Cervical Dystonia | — | 2006-05-05 |
| Completed | Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis Multiple Sclerosis | — | 2006-05-01 |
| Completed | Long-Term Improvement in Motor Learning by Transcranial Direct Current Stimulation Healthy Volunteers | — | 2006-04-07 |
| Completed | Treatment for Psychogenic Disorders Movement Disorders | — | 2006-04-07 |
| Completed | fMRI Studies of Task Specificity in Focal Hand Dystonia Focal Dystonia | — | 2006-03-30 |
| Completed | Neurophysiology of Task-Specificity of Focal Hand Dystonia Focal Dystonia | — | 2006-03-28 |
| Completed | Physiology of Weakness in Movement Disorders Movement Disorders | — | 2006-03-23 |
| Completed | Transcranial Direct Current Stimulation to Improve Hand Movement in Stroke Patients Stroke | — | 2006-03-23 |
| Completed | Volitional Swallowing in Stroke Patients With Chronic Dysphagia Stroke, Dysphagia | Phase 2 | 2006-03-17 |
| Completed | Brain Changes in Patients With Focal Hand Dystonia Focal Dystonia | — | 2006-03-17 |
| Completed | Reference Values for Plasma Catechols Healthy Volunteers, Normal Physiology | Phase 1 | 2006-03-08 |
| Completed | Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA) Kennedy's Disease, Spinal and Bulbar Muscular Atrophy | Phase 2 | 2006-03-01 |
| Completed | Interaction of Right and Left Brain Hemispheres in Learning Precision Hand Movements Interhemispheric Inhibition | — | 2006-02-17 |
| Completed | Effect of Atorvastatin (Lipitor) on Gene Expression in People With Vascular Disease Vascular Disease, Vascular Disease Risk | — | 2006-02-13 |
| Completed | Measures of Motor Impairment in Early Parkinson's Disease Parkinson's Disease | — | 2006-02-09 |
| Completed | Diffusion Tensor MRI to Distinguish Brain Tumor Recurrence From Radiation Necrosis Glioma Tumor Recurrence, Radiation Necrosis, Primary Brain Tumor | — | 2006-01-27 |
| Completed | Brain Networks Responsible for Sense of Agency Spatiotemporal Patterns | — | 2006-01-27 |
| Completed | Tactile Learning in Stroke Patients Stroke | — | 2006-01-25 |
| Completed | Electrical Polarization of the Brain in Corticobasal Syndrome Corticobasal Syndrome | Phase 2 | 2005-12-30 |
| Completed | Brain Changes in Adolescents While Imagining and Observing Aggressive Behavior Aggressive Behavior | — | 2005-12-14 |
| Completed | Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure Psychogenic Movement Disorders, Non-epileptic Seizures | — | 2005-11-09 |
| Completed | Training for Diagnosing Neurological Disorders Musculoskeletal Physiology | — | 2005-11-04 |
| Completed | Brain Networks Responsible for Self-Agency Brain | — | 2005-10-27 |
| Completed | PET Imaging of GABA Receptors in Succinic Semialdehyde Dehydrogenase Deficiency Succinic Semialdehyde Dehydrogenase Deficiency, SSADH Deficiency | — | 2005-10-24 |
| Completed | Convection-Enhanced Delivery of Glucocerebrosidase to Treat Type 2 Gaucher Disease Type 2 Gaucher Disease | — | 2005-10-22 |
| Terminated | Moving a Paralyzed Hand Through Use of a Brain-Computer Interface Stroke | — | 2005-10-17 |
| Completed | Idebenone to Treat Friedreich's Ataxia Friedreich Ataxia | Phase 2 | 2005-09-27 |
| Completed | Brain Activity Associated With Tics in Patients With Tourette Syndrome Tourette Syndrome | — | 2005-08-30 |
| Completed | Movement-Related Brain Networks Involved in Hand Dystonia Movement Disorder, Focal Dystonia | — | 2005-08-25 |
| Completed | Brain Excitability in Patients With Succinic Semialdehyde Dehydrogenase Deficiency Succinic Semialdehyde, Dehydrogenase Deficiency, Diseases | — | 2005-08-16 |
| Completed | Deep Brain Stimulation to Treat Cervical Dystonia Cervical Dystonia | Phase 1 | 2005-08-01 |
| Completed | Mirroring a Movement Healthy | — | 2005-07-20 |
| Completed | Neuropathology of Spasmodic Dysphonia Voice Disorders, Spasmodic Dysphonia, Healthy | — | 2005-07-14 |
| Completed | Interhemispheric Plasticity in Humans Healthy | — | 2005-07-08 |
| Completed | MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle Sleep | — | 2005-06-28 |
| Completed | Double Blind Trial of DC Polarization in FTD Dementia | Phase 2 | 2005-06-28 |
| Completed | Motor Performance in Chronic Stroke Patients Stroke | — | 2005-04-28 |
| Completed | Effects of Two Different Kinds of Exercise on Stroke Rehabilitation Cerebrovacular Accident, Paresis | — | 2005-04-13 |
| Completed | Talampanel to Treat Parkinson's Disease Parkinson Disease | Phase 2 | 2005-04-01 |
| Completed | Study to Collect Data on Fabry Disease Patients With Enhanceable Alpha-Galactosidase A Activity Fabry Disease | — | 2005-03-28 |
| Completed | Transcranial Electrical Polarization to Treat Focal Hand Dystonia Dystonia, Focal Hand Dystonia, FHD | Phase 2 | 2005-03-18 |
| Completed | Deep Brain Stimulation for Cervical Dystonia Dystonia, Generalized Primary Dystonia | Phase 2 | 2005-03-01 |
| Completed | Genetic Characterization of Parkinson's Disease Parkinson Disease, PD, Movement Disorder | — | 2005-03-01 |
| Completed | Nitrite Infusion in Healthy Volunteers Healthy | Phase 1 | 2005-02-04 |
| Completed | Effect of Surface Electrical Stimulation on Movement of the Larynx Healthy | — | 2005-02-01 |
| Completed | Brain Function in Focal Dystonia Dystonia | — | 2005-01-31 |
| Completed | Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tre Essential Tremor | Phase 2 | 2005-01-01 |
| Completed | Brain Reorganization Following Constraint-Induced Therapy in Children With Cerebral Palsy Cerebral Palsy | — | 2004-12-27 |
| Completed | Biomarkers in Multiple Sclerosis Multiple Sclerosis | — | 2004-12-17 |
| Completed | Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis Multiple Sclerosis | — | 2004-12-08 |
| Completed | Safety Study of Interferon Beta 1a to for Acute Stroke Cerebrovascular Accident | Phase 1 | 2004-11-17 |
| Completed | Brain Activities Associated With Different Facial Expressions Using Blood Oxygenation Level Dependent Function Healthy | — | 2004-11-09 |
| Completed | Non-Pharmacologic Therapy for Neurocardiogenic Syncope Syncope | Phase 2 | 2004-11-08 |
| Completed | Replagal Enzyme Replacement Therapy for Adults With Fabry Disease Fabry Disease | Phase 4 | 2004-11-01 |
| Completed | The Functional Anatomy of Personality Trait Knowledge: An fMRI Study Healthy | — | 2004-10-29 |
| Completed | Propranolol to Treat Fainting in Children With Sympathoadrenal Imbalance Syncope | Phase 2 | 2004-10-01 |
| Completed | Effects of Lithium and Divalproex'on Brain-Derived Neurotrophic Factor in Huntington's Disease Huntington's Disease | Phase 2 | 2004-10-01 |
| Completed | Neural Correlates of Observation of Tactile Stimulation in Healthy Subjects Healthy | — | 2004-09-03 |
| Completed | Rituximab to Treat Stiff Person Syndrome Stiff Person Syndrome | Phase 2 | 2004-09-01 |
| Completed | Lisuride Patch to Treat Parkinson's Disease Parkinson Disease | Phase 2 | 2004-08-04 |
| Completed | Treatment Study of Frontotemporal Dementia Frontotemporal Lobar Degeneration | — | 2004-07-23 |
| Completed | Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumors Glioblastoma | Phase 3 | 2004-07-01 |
| Completed | Effect of Lithium and Divalproex in Alzheimer's Disease Alzheimer Disease | Phase 2 | 2004-07-01 |
| Completed | Effect of Direct Current Polarization on Brain Function Healthy | — | 2004-07-01 |
| Completed | Biological Markers in Parkinson's Disease Parkinson Disease | — | 2004-07-01 |
| Completed | ACP-103 to Treat Parkinson's Disease Parkinson's Disease, Dyskinesias | Phase 2 | 2004-06-25 |
| Completed | Brain Electrical Stimulation to Enhance Recovery After Stroke Stroke | — | 2004-06-09 |
| Completed | Herpes Virus-6 and Epilepsy Epilepsy | — | 2004-06-01 |
| Completed | Observational Learning in Stroke Patients Stroke | — | 2004-05-25 |
| Completed | Role of the Brain in Making Economic Decisions Healthy | — | 2004-05-15 |
| Completed | Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives Dystonia | — | 2004-05-11 |
| Completed | Pelvic Pain in Women With Endometriosis Endometriosis, Chronic Pelvic Pain | — | 2004-04-22 |
| Completed | Language and Emotional Function in Patients With Temporal Lobe Epilepsy Epilepsy, Temporal Lobe | — | 2004-04-09 |
| Completed | Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder Tourette Syndrome, Tic Disorders | — | 2004-04-08 |
| Completed | Brain Physiology in Polio Survivors Postpoliomyelitis | — | 2004-04-06 |
| Completed | Timing of Voluntary Movement in Patients With Schizophrenia Schizophrenia | — | 2004-04-06 |
| Completed | Rhythm Perception and Generation Healthy | — | 2004-03-22 |
| Completed | Octanol to Treat Essential Tremor Essential Tremor | Phase 2 | 2004-03-01 |
| Completed | Alemtuzumab to Treat Sporadic Inclusion Body Myositis Myositis, Inclusion Body | Phase 2 | 2004-03-01 |
| Completed | Brain Activity in Visual-Motor Behavior Healthy | — | 2004-02-06 |
| Completed | Hu Mik-Beta-1 to Treat HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis HTLV-1 | Phase 1 | 2004-02-03 |
| Completed | Study of Brain Function During Cognitive Tasks Healthy | — | 2004-02-02 |
| Completed | Direct Current Brain Polarization in Frontotemporal Dementia Pick Disease of the Brain | Phase 1 | 2004-02-01 |
| Completed | Phase 1 Trial of Idebenone to Treat Patients With Friedreich's Ataxia Friedreich Ataxia | Phase 1 | 2004-02-01 |
| Completed | Brain Control of Movements in Cerebral Palsy Cerebral Palsy | — | 2004-01-23 |
| Completed | Brain Changes Associated With Learning a Motor Task Healthy | — | 2004-01-22 |
| Completed | Spinal Reflexes in Motor Skill Learning Healthy | — | 2004-01-01 |
| Completed | Levetiracetam Treatment of L-dopa Induced Dyskinesias Dyskinesias, Parkinson Disease | Phase 2 | 2004-01-01 |
| Completed | Role of the Right Brain in Recovery of Language Function in Chronic Stroke Aphasia, Cerebrovascular Accident | — | 2004-01-01 |
| Completed | Alternative Dosing and Regimen of Replagal to Treat Fabry Disease Fabry Disease | Phase 2 | 2004-01-01 |
| Completed | Enhanced Tactile Memory in the Blind Blindness | — | 2004-01-01 |
| Completed | Relationship Between Sensory and Motor Systems in Restless Leg Syndrome Restless Legs Syndrome | — | 2003-12-12 |
| Completed | Spinal Cord Plasticity Healthy | — | 2003-12-01 |
| Completed | Surgery Versus Radiosurgery to Treat Metastatic Brain Tumors Brain Neoplasms, Neoplasm Metastasis | Phase 4 | 2003-12-01 |
| Completed | Role of the Brain in Processing Visually Presented Objects Healthy, Motor Skills | — | 2003-11-18 |
| Completed | MRI in Autosomal Dominant Partial Epilepsy With Auditory Features Epilepsies, Partial | — | 2003-11-10 |
| Completed | Improvement of Use Dependent Plasticity in Chronic Stroke Patients Healthy, Cerebrovascular Accident | Phase 1 | 2003-11-06 |
| Completed | The Physiology of Tricks Dystonia, Torticollis | — | 2003-11-01 |
| Completed | Classification of Cerebral Palsy Subtypes Cerebral Palsy | — | 2003-11-01 |
| Completed | Zenapax (Daclizumab) to Treat Relapsing Remitting Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting | Phase 2 | 2003-10-30 |
| Completed | Non-Invasive Seizure Localization in Patients With Medically Refractory Localization Related Epilepsy: Synchro Epilepsy | — | 2003-10-17 |
| Completed | An Open-Label Maintenance Study of the Enzyme Replacement Therapy Replagal in Patients With Fabry Disease Fabry Disease | Phase 1 | 2003-10-01 |
| Completed | Use of Dynamic Contrast-Enhanced Magnetic Resonance Imaging to Assess Tumor-Associated Vasculature in Patients Breast Neoplasms | — | 2003-10-01 |
| Withdrawn | E-Selectin Nasal Instillation to Prevent Secondary Stroke Ischemic Attack, Transient, Transient | Phase 1 | 2003-10-01 |
| Completed | Analysis of Brain Metastasis in Patients With Breast Cancer, With and Without Over-Expression of HER-2 Breast Neoplasms | — | 2003-10-01 |
| Completed | Activating Effects of Sleep Deprivation on Synchronized MEG-EEG Recordings of Epilepsy Patients With Non-Diagn Epilepsy | — | 2003-10-01 |
| Completed | Brain Activation During Simple Vocal Behaviors Auditory Perception | — | 2003-10-01 |
| Completed | An Open-Label Clinical Trial of Replagal Enzyme Therapy in Children Ages 7-17 Years With Fabry Disease Fabry Disease | Phase 2 | 2003-10-01 |
| Completed | Brain Function in Primary Lateral Sclerosis Motor Neuron Disease | — | 2003-10-01 |
| Completed | Analysis of Brain Metastasis in Patients With Lung Cancer Carcinoma, Non-Small -Cell Lung | — | 2003-10-01 |
| Completed | Evaluation of Chronic Orthostatic Intolerance Syncope | — | 2003-09-26 |
| Completed | Improving Motor Learning in Stroke Patients Cerebrovascular Accident | — | 2003-08-11 |
| Completed | Reducing Seizure Frequency Using Cooling of the Head and Neck Epilepsy, Seizures | Phase 2 | 2003-08-11 |
| Completed | The Effect of Dopamine on Motor Skills Training Cerebrovascular Accident | — | 2003-08-08 |
| Completed | Studying Use-Dependent Plasticity Healthy | — | 2003-08-05 |
| Completed | Brain Mapping of Voice Control Voice Disorders | — | 2003-08-02 |
| Terminated | Modafinil to Treat Fatigue in Post-Polio Syndrome Postpoliomyelitis Syndrome | Phase 3 | 2003-08-01 |
| Completed | Investigating Endothelial Precursor Cells (EPCs) Central Nervous System | — | 2003-08-01 |
| Completed | Light Scattering Spectroscopy to Determine Brain Tumors Epilepsy, Temporal Lobe, Temporal Lobe | — | 2003-08-01 |
| Completed | Evaluating the Remote Effects of Stroke With MRI and PET Scans Cerebrovascular Accident | — | 2003-06-19 |
| Completed | Investigating the Safety of srTMS in the Treatment of Parkinson's Disease Parkinson Disease | Phase 1 | 2003-06-18 |
| Completed | Using fMRI to Understand the Roles of Brain Areas for Fine Hand Movements Ideomotor Apraxia | — | 2003-06-16 |
| Recruiting | Evaluation and Treatment of Neurosurgical Disorders Neurologic Disorders | — | 2003-06-04 |
| Completed | Studying Automatic Movements in Patients With Parkinson's Disease Parkinson Disease | — | 2003-06-01 |
| Completed | Stimulating Deep Brain Regions With a Magnetic Stimulator Healthy | — | 2003-06-01 |
| Completed | Measuring Levels of SMN in Blood Samples of SMA Patients Spinal Muscular Atrophy | — | 2003-05-19 |
| Completed | Investigating the Cognitive Processes That Underlie Social Knowledge and Behavior Healthy | — | 2003-05-07 |
| Completed | Magnetic Resonance Imaging of Calculus Problem Solving Healthy | — | 2003-05-01 |
| Completed | MRI Study of Self-Perception of Postural Stability Healthy, Postural Stability | — | 2003-05-01 |
| Completed | Magnetic Resonance Imaging of the Brain in Social and Emotional Reasoning Healthy | — | 2003-05-01 |
| Completed | Magnetic Resonance Imaging of the Brain in Emotional Processing Healthy | — | 2003-05-01 |
| Completed | Combination Anti-Platelet and Anti-Coagulation Treatment After Lysis of Ischemic Stroke Trial (CATALIST) Ischemic Stroke | Phase 2 | 2003-05-01 |
| Completed | Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance Neurocardiogenic Syncope | Phase 4 | 2003-05-01 |
| Completed | Hypnosis in Autonomic Function Vasovagal Syncope, Postural Tachycardia Syndrome, Hypnosis | — | 2003-05-01 |
| Terminated | Evaluation of Primary Chronic Autonomic Failure Autonomic Nervous System Diseases | — | 2003-04-10 |
| Completed | Single Photon Emission Computed Tomography to Study Receptors in Parkinson's Disease Parkinson Disease | — | 2003-04-01 |
| Completed | Postural Control in the Elderly Musculoskeletal Physiology, Healthy | — | 2003-04-01 |
| Completed | Effect of Talampanel (an AMPA Receptor Blocker) on Brain Activity Healthy | Phase 2 | 2003-04-01 |
| Completed | The Role of Gene Changes in Brain Tumor Formation and Growth Glioma | — | 2003-04-01 |
| Completed | Brain Plasticity of Verbal Memory in the Blind Blindness | — | 2003-04-01 |
| Completed | Neurophysiological Studies in Patients With Paroxysmal Hyperkinetic Movement Disorders Movement Disorders | — | 2003-03-21 |
| Completed | Development of Techniques for Use in MRI With a Magnetic Field of 7 Tesla Healthy, Magnetic Resonance Imaging | — | 2003-03-21 |
| Completed | Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement Tourette Syndrome, Tic Disorders | — | 2003-03-10 |
| Completed | Nervous System Function in Normal Volunteers During Cycling Training Healthy | Phase 1 | 2003-03-04 |
| Completed | Dextromethorphan to Treat Patients With Voice Spasms Voice Disorders | Phase 1 | 2003-03-04 |
| Completed | Ischemic Nerve Block to Improve Hand Function in Stroke Patients Cerebrovascular Accident | — | 2003-03-01 |
| Completed | Transcranial Direct Current Stimulation to Treat Symptoms of Parkinson's Disease Parkinson Disease | Phase 2 | 2003-03-01 |
| Completed | Registry of Fabry Disease - A Multicenter Observational Study Fabry Disease | — | 2003-02-13 |
| Completed | Brain Use of Sensory Information to Generate Movement Healthy | — | 2003-02-01 |
| Completed | Effects of Antiepileptic Drugs on Brain Excitability Healthy | — | 2003-02-01 |
| Completed | Survey of Sensory and Motor Tricks in Focal Dystonia Focal Dystonia | — | 2003-02-01 |
| Completed | Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome Restless Legs Syndrome | — | 2003-01-14 |
| Completed | Brain Encoding for Memory Healthy | — | 2003-01-01 |
| Completed | Minocycline to Treat Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis | Phase 3 | 2003-01-01 |
| Completed | Single Photon Emission Computed Tomography (SPECT) to Study Paroxysmal Hyperkinetic Movement Disorders Hyperkinesis | — | 2003-01-01 |
| Completed | Learning a Motor Task Through Observation Healthy | — | 2002-12-23 |
| Completed | Rituximab to Treat Neuropathy With Anti-MAG Antibodies Polyneuropathies | Phase 2 | 2002-11-27 |
| Completed | Preliminary Study of Transcranial Magnetic Stimulation for Stroke Rehabilitation Cerebrovascular Accident | Phase 1 | 2002-11-18 |
| Completed | Transcranial Magnetic Stimulation and Electrical Stimulation of Nerves to Study Focal Dystonia Dystonic Disorders | — | 2002-11-13 |
| Completed | Effects of Direct Current Brain Stimulation on Cognition Electrical Stimulation of the Brain | Phase 1 | 2002-11-01 |
| Completed | Alpha-Galactosidase A Replacement Therapy for Fabry Disease Fabry Disease | Phase 2 | 2002-11-01 |
| Completed | Transcranial Magnetic Stimulation to Treat Epilepsy Epilepsy | Phase 2 | 2002-10-01 |
| Completed | Brain Inhibition of Muscle Movement in Normal Volunteers Dystonic Disorders | — | 2002-10-01 |
| Completed | Comparison of the Risk of Stroke With On- Versus Off-Pump Coronary Artery Bypass Grafting Coronary Disease | — | 2002-09-25 |
| Completed | ReoPro and Retavase to Treat Acute Stroke Cerebrovascular Accident | Phase 2 | 2002-09-24 |
| Completed | Transcranial Magnetic Stimulation to Study Imagination of Movement Healthy | — | 2002-09-01 |
| Completed | Role of Hormones in Susceptibility to Seizures in Women With Epilepsy Epilepsy | — | 2002-07-26 |
| Completed | OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients With Neuronopathic Gaucher Disea Gaucher Disease | Phase 2 | 2002-07-05 |
| Completed | How the Loss of Dopamine and Dopamine-Restoring Medicines Affect Movement Performance Parkinson Disease | — | 2002-06-19 |
| Completed | MRI Language Studies in Young Children Healthy | — | 2002-06-07 |
| Completed | Genetic Studies to Identify Stroke Subtypes and Outcome Cerebrovascular Disease, Stroke | — | 2002-06-03 |
| Completed | Nerve Stimulation to Modify a Spinal Reflex Healthy | — | 2002-06-01 |
| Completed | JP-1730 to Treat Parkinson's Disease Parkinson Disease | Phase 2 | 2002-06-01 |
| Completed | Hypothermia to Treat Severe Brain Injury Brain Injuries, Hypothermia | N/A | 2002-05-01 |
| Completed | Functional Coupling of Cortico-Cortical and Cortico-Muscular Connections During Motor Movements: An Electrocor Epilepsy | — | 2002-05-01 |
| Completed | Immunological Mechanisms of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis Multiple Sclerosis | Phase 2 | 2002-05-01 |
| Completed | Study of GABA-A Receptors in the Generation of Tics in Patients With Tourette's Syndrome Tourette Syndrome | — | 2002-04-24 |
| Completed | Magnetic Resonance Imaging in Children and Adults Using Arterial Spin Tagging Techniques Healthy | — | 2002-04-18 |
| Completed | Study of Tics in Patients With Tourette's Syndrome and Chronic Motor Tic Disorder Tourette Syndrome, Tic Disorders | — | 2002-04-17 |
| Completed | High-Dose Intravenous Immunoglobulin to Treat Cerebellar Degeneration Spinocerebellar Degenerations | Phase 2 | 2002-04-01 |
| Completed | MRI Brain Studies in Patients With HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis Tropical Spastic Paraparesis | — | 2002-04-01 |
| Completed | ReoPro and Retavase to Restore Brain Blood Flow After Stroke Cerebrovascular Accident | Phase 2 | 2002-03-01 |
| Completed | The Role of Dopamine in Motor Learning in Healthy Subjects and Patients With Parkinson's Disease Parkinson Disease, Healthy | — | 2002-03-01 |
| Terminated | Brain Anatomy in Dystonia Dystonia, Healthy | — | 2002-02-27 |
| Completed | Cause, Development, and Progression of Stiff-Person Syndrome Stiff-Person Syndrome | — | 2002-02-11 |
| Completed | GABA Levels in the Brains of Blind People Vision, Blind | — | 2002-02-11 |
| Completed | Magnetic Resonance Spectroscopy to Evaluate Tourette s Syndrome Tourette Syndrome | — | 2002-02-11 |
| Completed | Immune Abnormalities in Sporadic Inclusion Body Myositis Sporadic, Inclusion Body, Myositis | — | 2002-02-04 |
| Completed | Donepezil to Treat Dementia in Parkinson's Disease Parkinson Disease | Phase 4 | 2002-02-01 |
| Completed | Imaging Study of Automatic Movements Healthy | — | 2002-02-01 |
| Completed | Brain Control of Blinking Healthy | — | 2002-02-01 |
| Completed | Brain Activity During Production of Movement Healthy | — | 2002-01-22 |
| Completed | Interhemispheric Interactions Associated With Performance of Voluntary Movements in Patients With Stroke Motor Cerebrovascular Accident, Healthy | — | 2002-01-16 |
| Completed | Data Collection in Women With Fabry Disease Fabry Disease | — | 2002-01-01 |
| Completed | Surround Inhibition in Patients With Dystonia Dystonic Disorders, Healthy | — | 2002-01-01 |
| Completed | Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease Parkinson Disease | Phase 2 | 2002-01-01 |
| Completed | Effect of Transcranial Magnetic Stimulation on Free Will Healthy | — | 2002-01-01 |
| Completed | Role of Brain Region Changes in Tactile (Touch) Ability Following Nerve Block Tactile Spatial Acuity, Healthy | — | 2001-12-12 |
| Completed | Brain Control of Bimanual (Both Hands) Movements Healthy | — | 2001-12-10 |
| Completed | Comparison of Externally and Self-Initiated Movements Healthy | — | 2001-12-01 |
| Completed | Role of the Intact Hemisphere in Recovery of Motor Function After Stroke Cerebrovascular Accident | — | 2001-12-01 |
| Completed | Enhancement of Use-Dependent Plasticity by Somatosensory Stimulation in Chronic Stroke Cerebrovascular Accident | N/A | 2001-12-01 |
| Completed | Enhanced Tactile (Touch) Spatial Acuity in Upper Limb Amputees Amputation | — | 2001-12-01 |
| Completed | Temperature Response to a Head-Neck Cooling System Healthy | Phase 1 | 2001-11-01 |
| Completed | Brain Activation in Vocal and Motor Tics Tourette's Syndrome, Chronic Motor Tic Disorder, Chronic Motor Vocal Disorder | — | 2001-11-01 |
| Recruiting | Phenotype/Genotype Correlations in Movement Disorders Movement Disorder | — | 2001-10-22 |
| Completed | Study of Specimens Obtained During Epilepsy Surgery Epilepsy | — | 2001-10-10 |
| Completed | EEG and EMG Studies of Hand Dystonia Focal Dystonia | — | 2001-10-09 |
| Completed | Effect of Stimulus Rate on Cognitive and Motor Activity in Young Subjects, Elderly Subjects, and Patients With Parkinson's Disease | — | 2001-10-01 |
| Completed | EEG and EMG Analysis of Ideomotor Apraxia Ideomotor Apraxia | — | 2001-10-01 |
| Completed | Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex Intracranial Central Nervous System Disorder, Mental Disorder, Healthy | — | 2001-10-01 |
| Completed | Eye-Hand Coordination in Children With Spastic Diplegia Diplegia, Spastic | — | 2001-09-01 |
| Completed | Electrical Stimulation to Improve Hand Function in Patients With Chronic Stroke Cerebrovascular Accident | — | 2001-09-01 |
| Completed | Transcranial Magnetic Stimulation in Parkinson's Disease Parkinson Disease, Healthy | — | 2001-08-01 |
| Completed | Motor Training to Treat Hand Dystonia Focal Dystonia | Phase 2 | 2001-08-01 |
| Completed | Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Amyotrophic Lateral Sclerosis | — | 2001-08-01 |
| Completed | Motor Learning in Stroke Patients and Healthy Volunteers Stroke, Healthy | — | 2001-07-01 |
| Completed | Genetic Analysis of the Chiari I Malformation Syringomyelia, Type I Arnold Chiari Malformation | — | 2001-06-04 |
| Completed | Brain Excitability During Self-Paced Voluntary Movements Movement Disorder, Healthy | — | 2001-06-01 |
| Completed | Phenotype/Genotype Correlations in Neuromuscular Disorders Neuromuscular Disease | — | 2001-06-01 |
| Completed | Transcranial Magnetic Stimulation (TMS) Studies of Dystonia Dystonic Disorder, Healthy | — | 2001-06-01 |
| Completed | Study of Brain Control of Movement Movement Disorder, Healthy | — | 2001-06-01 |
| Completed | Cause and Pathogenesis of Neurometabolic Disorders Neurodegenerative Disease | — | 2001-05-13 |
| Completed | Differences in Brain Processing of First and Second Languages (Korean and English) Brain Disorder, Healthy | — | 2001-05-01 |
| Completed | Study of Air Stream in Voice Production Spastic Dysphonia, Healthy | Phase 1 | 2001-05-01 |
| Completed | 1-Octanol to Treat Essential Tremor Essential Tremor | Phase 1 | 2001-05-01 |
| Completed | Screening and Natural History: Primary Lateral Sclerosis and Related Disorders Primary Lateral Sclerosis | — | 2001-05-01 |
| Completed | Language Stimuli Screening in Children Language Disorder, Healthy | — | 2001-05-01 |
| Completed | Safety Study of Idebenone to Treat Friedreich's Ataxia Friedreich Ataxia | Phase 1 | 2001-05-01 |
| Terminated | Evaluation and Treatment of Patients With Epilepsy Epilepsy | — | 2001-05-01 |
| Completed | The Natural History and Pathogenesis of Mucolipidosis Type IV Mucolipidosis Type IV | — | 2001-04-27 |
| Completed | Diagnostic Evaluation of Patients With Neuromuscular Disease Neuromuscular Disease | — | 2001-04-16 |
| Completed | Physiologic Studies of Spasticity Muscle Spasticity, Healthy | — | 2001-04-13 |
| Completed | Magnetic Resonance Imaging to Investigate Silent Strokes During Neck and Skull Angioplasty Brain Ischemia | — | 2001-04-01 |
| Completed | Effects of Flumazenil on Brain Excitability Stroke, Healthy | — | 2001-04-01 |
| Completed | Amlodipine Plus Botulinum Toxin for Focal Dystonia Focal Dystonia | Phase 2 | 2001-04-01 |
| Completed | Riluzole to Treat Parkinson's Disease Parkinson's Disease | Phase 2 | 2001-03-01 |
| Terminated | E-Selectin Nasal Spray to Prevent Stroke Recurrence Cerebrovascular Accident, Transient Ischemic Attack | Phase 2 | 2001-03-01 |
| Active Not Recruiting | Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease Hemangioblastoma, Hippel Lindau Disease | — | 2001-02-15 |
| Completed | Study and Surgical Treatment of Syringomyelia Syringomyelia | — | 2001-02-08 |
| Completed | Rolipram to Treat Multiple Sclerosis Multiple Sclerosis | Phase 2 | 2001-02-01 |
| Recruiting | Natural History of Stroke: Cause and Development Brain Disease, Ischemic Attack, Transient, Cerebrovascular Accident | — | 2001-01-26 |
| Completed | EMD 128130 for the Treatment of Parkinson's Disease Parkinson's Disease | Phase 2 | 2001-01-01 |
| Completed | Ketogenic Diet in Lafora Disease Lafora Disease | — | 2000-12-01 |
| Completed | Gluten-Free Diet in Patients With Gluten Sensitivity and Cerebellar Ataxia Celiac Disease, Cerebellar Ataxia, Healthy | — | 2000-11-01 |
| Completed | Study of Brain Changes Shaped by Experience Healthy, Neurologic Manifestations | — | 2000-10-01 |
| Completed | KW-6002 to Treat Parkinson's Disease Parkinson's Disease | Phase 2 | 2000-10-01 |
| Completed | Hand Exercise and Upper Arm Anesthesia to Improvements Hand Function in Chronic Stroke Patients Cerebrovascular Accident | — | 2000-10-01 |
| Completed | Sensory Training to Treat Focal Dystonia Dystonic Disorder | — | 2000-09-01 |
| Completed | Effect of Levetiracetam on Brain Excitability Healthy, Myoclonic Epilepsy | — | 2000-08-01 |
| Completed | Effects of Monoamine Reuptake Inhibitor NS2330 in Parkinson's Disease Parkinson's Disease | Phase 2 | 2000-08-01 |
| Recruiting | Study of New Magnetic Resonance Imaging Methods of the Brain Healthy Volunteer, Magnetic Resonance Imaging, Healthy | — | 2000-07-01 |
| Terminated | Brain Infusion of Muscimol to Treat Epilepsy Epilepsy | Phase 1 | 2000-06-23 |
| Completed | Continuously Infused Recombinant-Methionyl Human Glial Cell Line-Derived Neurotrophic Factor (GDNF) to Treat P Progressive Supranuclear Palsy | Phase 2 | 2000-06-01 |
| Completed | PET Scans in Normal Volunteers and Patients With Fabry Disease Fabry Disease, Healthy | — | 2000-04-01 |
| Completed | Study of Brain Activity During Speech Production and Speech Perception Developmental Articulation Disorder, Stuttering | — | 2000-03-14 |
| Recruiting | Study of Inherited Neurological Disorders Motor Neuron Disease, Muscular Disease, Muscular Dystrophy | — | 2000-02-18 |
| Completed | Study of LY300164 for the Treatment of Parkinson's Disease Dyskinesias, Parkinson Disease | Phase 2 | 2000-02-01 |
| Completed | Hypothermia During Intracranial Aneurysm Surgery Trial Aneurysm, Hypothermia, Subarachnoid Hemorrhage | Phase 3 | 2000-02-01 |
| Completed | Gentamicin Treatment of Muscular Dystrophy Becker Muscular Dystrophy, Duchenne Muscular Dystrophy | Phase 1 | 2000-02-01 |
| Completed | Electromyography to Diagnose Neuromuscular Disorders Healthy, Neuromuscular Disease, Postpoliomyelitis Syndrome | N/A | 2000-02-01 |
| Completed | Positron Emission Tomography (PET) to Study Brain Signaling Healthy | — | 2000-01-10 |
| Completed | 1-Octanol to Treat Essential Tremor Essential Tremor | Phase 1 | 2000-01-01 |
| Completed | Brain Imaging and Retreatment Study of Persistent Lyme Disease Lyme Disease, Lyme Neuroborreliosis | Phase 2 | 1999-12-01 |
| Completed | Detecting Malignant Brain Tumor Cells in the Bloodstream During Surgery to Remove the Tumor Astrocytoma, Glioblastoma, Glioma | — | 1999-10-01 |
| Completed | Blood Sampling for Neurochemical and Genetic Testing Autonomic Nervous System Disease, Healthy, Hypertension | — | 1999-10-01 |
| Completed | Oxandrolone Compared With a Placebo on Growth Rate in Girls With Growth Hormone-Treated Turner's Syndrome Turner's Syndrome | Phase 2 | 1999-10-01 |
| Completed | Electrical Muscle Stimulation to Aid Swallowing in Dysphagia Deglutition Disorder, Healthy | — | 1999-09-28 |
| Completed | Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes Williams Syndrome, Angelman Syndrome, Prader-Willi Syndrome | — | 1999-09-01 |