NCT00391716

Gabapentin Treatment of Alcohol Dependence

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: The Scripps Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Gabapentin treatment for alcohol dependence

Detailed description

This is a 12-week, double blind, placebo controlled, dose ranging study to evaluate the efficacy of gabapentin in treating outpatients with alcohol dependence. Subjects receive 900mg or 1800mg gabapentin or placebo daily for 12 weeks accompanied by weekly standardized counseling for alcohol-related behavior, with assessments of alcohol consumption, mood, sleep and alcohol-craving performed each week.

Conditions

• Alcoholism
• Alcohol Dependence

Interventions

Type	Name	Description
DRUG	Gabapentin 900mg	900 mg gabapentin daily for 12 weeks
BEHAVIORAL	behavioral counseling	The manual for standardized alcohol-related behavioral counseling was developed by Drs. Barbara Mason and Anita Goodman. The manual is available at alcoholfree.info.
DRUG	placebo	lactose capsule compounded to mimic gabapentin capsules
DRUG	gabapentin 1800mg	1800 mg gabapentin daily for 12 weeks

Timeline

• Start date: 2004-02-01
• Primary completion: 2009-07-01
• Completion: 2010-02-01
• First posted: 2006-10-24
• Last updated: 2014-11-10
• Results posted: 2014-11-10

Locations

1 site across 1 country: United States