| Recruiting | Feasibility of Integrating Olfactory Stimuli Into Virtual Reality Cue Exposure for Patients With Alcohol Depen NCT07388693 | Charite University, Berlin, Germany | N/A |
| Recruiting | Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of A NCT07216872 | Brainsway | N/A |
| Not Yet Recruiting | Can Selfcompassion Training Reduce Alcohol Consumption in Patients With Alcohol Use Disosrder ? NCT07131124 | Etablissement Public de Santé Barthélemy Durand | N/A |
| Recruiting | Psilocybin or Ketamine for Alcohol Use Disorder: An Active Comparator Trial NCT06405607 | University of Iowa | Phase 2 |
| Recruiting | Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder NCT06939088 | Anders Fink-Jensen, MD, DMSci | Phase 2 |
| Recruiting | Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study NCT06770556 | Wake Forest University Health Sciences | N/A |
| Recruiting | The Impact of Heavy Alcohol Use on Saliva and Oral Health NCT06684483 | National Institutes of Health Clinical Center (CC) | — |
| Recruiting | Validation of the French Version of the Prediction of the Alcohol Withdrawal Severity Scale (PAWSS) NCT06675539 | Etablissement Public de Santé Barthélemy Durand | — |
| Recruiting | A Clinical Trial to Assess Pharmacokinetic Profiles, Safety and Tolerability of IVL3004 and IVL4002 in Healthy NCT05620940 | Inventage Lab., Inc. | Phase 1 |
| Not Yet Recruiting | Psilocybin-assisted Therapy for Alcohol Use Disorder NCT06444243 | University of Sydney | Phase 2 |
| Recruiting | Virtual Incentive Treatment for Alcohol NCT06265506 | Washington State University | N/A |
| Not Yet Recruiting | Tracking Mood: The Effects of Daily Mood Tracking VAS on Alcohol Consumption in Adult Heavy Drinkers NCT06419647 | Ilona Myllyniemi | N/A |
| Completed | Presence and Relapse Rates in Patients With Alcohol Use Disorder Using Virtual Reality NCT06333457 | Charite University, Berlin, Germany | — |
| Recruiting | Neuromodulation and Mindfulness Patients With AUD NCT06308484 | Charite University, Berlin, Germany | N/A |
| Enrolling By Invitation | Effects of Ketone Supplementation on Acute Alcohol Withdrawal NCT06173973 | University of Pennsylvania | Phase 2 / Phase 3 |
| Active Not Recruiting | Telehealth Treatment for Alcohol Use Disorder NCT05747703 | Ria Health | N/A |
| Recruiting | MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder NCT05709353 | University of Sydney | Phase 2 |
| Completed | Nitrate Modulates Cognitive Impairment Via Oral Microbiota. NCT05963659 | Peking University Sixth Hospital | N/A |
| Completed | Does Semaglutide Reduce Alcohol Intake in Patients With Alcohol Use Disorder and Comorbid Obesity? NCT05895643 | Psychiatric Centre Rigshospitalet | Phase 2 |
| Withdrawn | Study of the Neural Substrates of Alcohol Craving by High-resolution Electroencephalography NCT05275166 | Rennes University Hospital | N/A |
| Recruiting | Trans-cranial Direct Current Stimulation on Alcohol Craving NCT05854693 | Taipei City Hospital | N/A |
| Withdrawn | Early Detection of Alcoholic Liver Disease NCT04070508 | University of Pittsburgh | — |
| Recruiting | High-dose Accelerated Theta Burst Stimulation for the Treatment of Alcohol Addiction NCT05738174 | Berthold Langguth, MD, Ph.D. | N/A |
| Not Yet Recruiting | Neurobiological Effects of Transcranial Direct Current Stimulation Treatment in Alcohol Use Disorder NCT04897295 | ITAB - Institute for Advanced Biomedical Technologies | N/A |
| Completed | Tech-Enabled CM for AUD at Scale NCT04581499 | DynamiCare Health | N/A |
| Unknown | TREAT Child Alcohol Use Disorder (C-AUD) in Eastern Uganda NCT04743024 | University of Bergen | — |
| Unknown | Impact of COVID-19 Outbreak on the Alcohol Consumption in Patients With Alcohol-related Liver Disease (ICoLD) NCT04876443 | King's College Hospital NHS Trust | — |
| Completed | Effect of Theta Burst Stimulation on Alcohol Cue Reactivity NCT04223154 | Wake Forest University Health Sciences | N/A |
| Unknown | Screening for Alcohol-related Cognitive Impairments in Cirrhotic Patients NCT04490330 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users NCT04154111 | Wake Forest University Health Sciences | N/A |
| Terminated | Targeting Non-virally Suppressed Adults With Alcohol Use Disorder in HIV Primary Care NCT04280068 | Research Foundation for Mental Hygiene, Inc. | N/A |
| Unknown | Cannabidiol (CBD) for the Treatment of Alcohol Withdrawal NCT04205682 | South West Sydney Local Health District | EARLY_Phase 1 |
| Recruiting | Patient Trajectories for Older Adults Admitted to Hospital for Alcohol-related Problems NCT04164940 | Helse Stavanger HF | — |
| Completed | Post-Marketing Surveillance Study of Nalmefene Hydrochloride Hydrate in Patients with Alcohol Dependence NCT04107051 | Otsuka Pharmaceutical Co., Ltd. | — |
| Recruiting | Safety and Efficacy of Fecal Microbiota Transplantation NCT04014413 | Chinese University of Hong Kong | N/A |
| Unknown | Efficacy of Repetitive Transcranial Magnetic Stimulation and Cognitive Behavioral Therapy on Alcohol Dependenc NCT03910686 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | N/A |
| Unknown | A Smartphone Based Intervention for the Prevention of Relapse in Alcohol Dependence NCT03952429 | Salus Klinik Lindow | N/A |
| Completed | RCT of Web-Based Behavioral Sleep Intervention for Individuals With Alcohol Use Disorder NCT03493958 | National Institutes of Health Clinical Center (CC) | N/A |
| Completed | Varenicline and Bupropion for Alcohol Use Disorder NCT04167306 | Vastra Gotaland Region | Phase 2 |
| Completed | Skills-training for Reducing Risky Alcohol Use in App Form NCT03696888 | Karolinska Institutet | N/A |
| Withdrawn | Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence. NCT02824354 | Centre Hospitalier Universitaire, Amiens | Phase 3 |
| Completed | Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological Treatment for Alcohol Use Diso NCT03842670 | University of New Mexico | N/A |
| Unknown | Qi Gong as a Method of Craving Reduction in Severe Addict Patients NCT03589118 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol NCT03548714 | Pop Test Oncology LLC | Phase 1 |
| Unknown | The Efficacy and Neurobehavioural Mechanism of N-acetyl Cysteine (NAC) for Alcohol Dependence NCT03879759 | South West Sydney Local Health District | Phase 2 |
| Completed | Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders NCT03732248 | Medical University of South Carolina | Phase 1 |
| Completed | Individualizing Incentives for Alcohol in the Severely Mentally Ill NCT03481049 | Washington State University | N/A |
| Completed | Research on the Efficacy of the "T.O.P. Computer Training" Procedure in the Treatment of Alcohol Dependence NCT03338361 | University Ghent | N/A |
| Completed | Remote Alcohol Monitoring and Episodic Thinking NCT03340051 | Virginia Polytechnic Institute and State University | N/A |
| Completed | Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism NCT02901041 | Boston University Charles River Campus | Phase 3 |
| Recruiting | Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in Adolescent NCT06262958 | Kuopio University Hospital | N/A |
| Unknown | Assessment of Valproate on Ethanol Withdrawal NCT03235531 | CAMC Health System | Phase 4 |
| Unknown | Defining the Clinical Role of Topiramate in the Treatment of Alcohol Dependence in Australia NCT03479086 | South West Sydney Local Health District | Phase 3 |
| Completed | The Self Match Study: A Study of Informed Choice in the Treatment of Addiction NCT03278821 | Kjeld Andersen | N/A |
| Completed | Fish Oil vs. Placebo on Subjective Effects of Alcohol NCT03010917 | Yale University | Phase 1 |
| Unknown | The Approach and Avoidance Task (AAT) in Alcoholic Inpatients NCT04054336 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Terminated | Advanced Nurses vs. General Practitioners for the Management of Outpatient Alcohol Detox: a Safety and Cost Co NCT03056365 | University Hospital, Lille | N/A |
| Completed | Learning to Resist the Urge: Inhibition Training in Abstinent Patients With Alcohol Use Disorders NCT02968537 | University of Bern | N/A |
| Completed | A Tailored Physical Activity Smartphone App for Patients With Alcohol Dependence NCT02958280 | Butler Hospital | N/A |
| Completed | Progesterone Effect on Individuals Diagnoses With AD and PTSD. NCT02187224 | Yale University | Phase 2 / Phase 3 |
| Completed | Reducing Alcohol Dependence Among HIV-Positive Individuals NCT02501057 | Research Foundation for Mental Hygiene, Inc. | N/A |
| Completed | 10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine Dependence NCT03238859 | Medical University of South Carolina | Phase 2 |
| Terminated | Treatment for Alcohol Dependence With Gabapentin NCT02771925 | Dayanand Medical College and Hospital | Phase 4 |
| Completed | Alcohol Disorder hOsPital Treatment Trial NCT02478489 | Boston University | Phase 4 |
| Unknown | Binge Drinking And Addiction : Case-Control Study in Hospital NCT03204214 | Marie-Pierre TAVOLACCI | — |
| Completed | Study of Structural Imaging NCT02564991 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | A Single-center, Open-label, Single-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Pro NCT02679469 | Otsuka Pharmaceutical Co., Ltd. | Phase 1 |
| Completed | Use of Selincro and Impact on Usual Practice NCT02492581 | University of Bordeaux | — |
| Completed | Usability Study for SOBERLINK System NCT02650180 | Soberlink Healthcare LLC | N/A |
| Completed | Internet-based vs Face-to-face Treatment for Alcohol Dependence NCT02888002 | Karolinska Institutet | N/A |
| Completed | Multimodal Neuroimaging of Stress and Reward Cues to Assess Alcoholism Risk and Relapse NCT02616094 | Yale University | N/A |
| Completed | Lifestyle Physical Activity Intervention for Depressed Alcohol Dependent Women NCT02705898 | Butler Hospital | N/A |
| Completed | Neurofeedback & Alcohol Dependence NCT02486900 | Cardiff University | N/A |
| Completed | Epi-Genetic Modulators of Fear Extinction in Alcohol Dependence NCT02438969 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | A Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol Dependenc NCT02382276 | Otsuka Pharmaceutical Co., Ltd. | Phase 3 |
| Completed | Biomarkers to Measure Treatment Response for Alcohol Dependence NCT02315885 | University of Maryland, Baltimore | N/A |
| Completed | Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users NCT02445339 | NYU Langone Health | Phase 4 |
| Completed | Minocycline's Effects on Alcohol Responses in Humans NCT02187211 | Yale University | Phase 1 |
| Completed | Oxytocin Treatment of Alcohol Dependence NCT02251912 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Glutamatergic Modulation of Disordered Alcohol Use NCT02539511 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Unknown | Designing a Mobile App for Veterans With Substance Use Problems NCT01812187 | Michael E. DeBakey VA Medical Center | N/A |
| Completed | Anonymous Treatment on the Internet for Alcohol Dependence: A Randomised, Controlled Trial NCT02377726 | Karolinska Institutet | N/A |
| Terminated | Study of Familiarity in Alcohol Dependence NCT02881424 | University Hospital, Lille | — |
| Completed | A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate NCT02364947 | Otsuka Pharmaceutical Co., Ltd. | Phase 3 |
| Completed | Ambivalence Model of Craving: Re-examining the Drinking-craving Relationship NCT01883089 | University of South Florida | N/A |
| Completed | Efficacy and Safety Evaluating Study of Odelepran for the Use in Patient With Alcohol Dependence NCT03663374 | R-Pharm | Phase 3 |
| Completed | Safety and Pharmacodynamic Study of GET 73 in Alcohol Dependent NCT01842503 | Laboratorio Farmaceutico Ct S.r.l. | Phase 1 / Phase 2 |
| Completed | Outpatient Psychotherapeutic Treatment for Alcohol Dependent Individuals With Comorbid Psychiatric Disorders NCT02141789 | University of Konstanz | N/A |
| Completed | Automated Bilingual Computerized Alcohol Screening and Intervention in Latinos (AB-CASI) NCT02247388 | Yale University | N/A |
| Completed | Pharmacological Treatment of Comorbid Alcohol and Marijuana Withdrawal and Dependence NCT02210195 | The Scripps Research Institute | Phase 2 |
| Completed | Mifepristone Treatment of Alcohol Use Disorder NCT02179749 | The Scripps Research Institute | Phase 2 |
| Completed | Treatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro® As-needed Use NCT02197598 | H. Lundbeck A/S | Phase 4 |
| Terminated | Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care NCT02195817 | H. Lundbeck A/S | Phase 4 |
| Completed | Impact of Prevention Awareness Group (PAG) on Treatment Attendance and Drug Abstinence Among Substance User NCT02173041 | Macmillan Research Group UK | N/A |
| Recruiting | Characterization Imaging Instruments in Alcoholics and Non-Alcoholics NCT02108080 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | Cell Phone Technology Targeting ART and Naltrexone Adherence and Alcohol Use NCT02603471 | University of California, Los Angeles | N/A |
| Completed | Alcohol Consumption and Stress at Patients Alcohol-dependants NCT02087358 | Assistance Publique - Hôpitaux de Paris | — |
| Withdrawn | Traits Associated With Early Life Stress Among Treatment-Seeking Alcoholics NCT02181608 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence NCT02061293 | NYU Langone Health | Phase 2 |
| Completed | Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary Care NCT01893827 | NYU Langone Health | Phase 4 |
| Completed | Can Cognitive-bias Modification Training During Inpatient Alcohol Detoxification Reduce Relapse Rates Post-dis NCT02634476 | Turning Point | N/A |
| Recruiting | Behavioral and Functional Task Development, Implementation, and Testing NCT02108054 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | N/A |
| Completed | Study of the BDNF-Val66Met Polymorphism in Alcohol-dependent Subjects in Relation to Abstinence After Withdraw NCT02146963 | Centre Hospitalier Esquirol | — |
| Completed | Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics NCT01657760 | VA Office of Research and Development | Phase 1 |
| Completed | Citicoline for Alcohol Dependence NCT02074735 | University of Texas Southwestern Medical Center | Phase 4 |
| Withdrawn | Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Depen NCT01853293 | Mclean Hospital | Phase 2 |
| Completed | A Novel Compound for Alcoholism Treatment NCT02039349 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 1 |
| Completed | Effects of Acute Exercise on Various Parameters in Individuals With Alcohol Use Disorders NCT02664727 | University of Thessaly | N/A |
| Completed | Telephone-Based Continuing Care for Alcohol Dependence NCT02030093 | University of Bern | — |
| Completed | Effect of Anti-craving Medication on Cognitive Functions in Alcohol Dependence: an ERP Study NCT02107352 | Brugmann University Hospital | — |
| Completed | Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral S NCT01969617 | H. Lundbeck A/S | Phase 1 |
| Unknown | The Efficacy of A Smartphone-based Support System to Reinforce Alcohol Abstinence in Treatment-seeking Patient NCT02385643 | Ming-Chyi Huang | N/A |
| Completed | Eye Movement Desensitization and Reprocessing (EMDR) in Alcohol Dependent Patients NCT01828866 | IrisZorg | N/A |
| Completed | Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence NCT01847469 | Yale University | Phase 2 |
| Completed | Oral vs. Injectable Naltrexone for Hospitalized Veterans With Alcohol Dependence NCT01856712 | University of Wisconsin, Madison | Phase 3 |
| Completed | Baclofen in the Treatment of Alcohol Dependence With or Without Alcoholic Liver Disease NCT01711125 | South West Sydney Local Health District | Phase 3 |
| Unknown | Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD NCT01663337 | University of Washington | N/A |
| Completed | Carisbamate as a Potential Treatment for Alcohol Dependence NCT02435381 | Baylor College of Medicine | Phase 1 / Phase 2 |
| Completed | A Controlled Trial of Topiramate Treatment for Alcohol Dependence in Veterans With PTSD NCT01749215 | University of California, San Francisco | Phase 4 |
| Completed | ABT-436 for Alcohol Dependence NCT01613014 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Terminated | Topiramate to Reduce Heavy Drinking in HIV-Positive Heavy Drinkers NCT01764685 | University of Pennsylvania | Phase 2 |
| Completed | Dutasteride Treatment for the Reduction of Heavy Drinking in Men NCT01758523 | UConn Health | Phase 4 |
| Completed | Oxytocin Treatment of Alcohol Dependence NCT02275611 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | Baclofen for Treating Anxiety and Alcoholism NCT01751386 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Efficacy and Safety of Baclofen for Maintenance of Abstinence in Alcohol Dependent Patients NCT01738282 | Ethypharm | Phase 3 |
| Unknown | The Effects of Treatment With Naltrexone in Alcohol and Cannabis-dependent Patients NCT01560013 | Tel-Aviv Sourasky Medical Center | N/A |
| Completed | Health Mobile Cognitive Stimulation in Alcohol Use Disorder NCT01942954 | Pedro Gamito | N/A |
| Terminated | Effectiveness of TCC Followed by MBCT and Predictive Factors (Genetic, Clinical and Cognitive) Response NCT02472483 | Centre Hospitalier St Anne | N/A |
| Terminated | Topiramate for Alcohol Use in Posttraumatic Stress Disorder NCT01408641 | University of Maryland, Baltimore | N/A |
| Terminated | Pharmacotherapy for Alcohol Dependence in Convicted Drinking Drivers NCT01638377 | Centre for Addiction and Mental Health | Phase 4 |
| Withdrawn | The Use of Anticonvulsants for Treatment of Patients With Alcohol Dependence and Post Traumatic Stress Disorde NCT00571246 | Yale University | Phase 3 |
| Terminated | Role of Proinflammatory Signaling in Alcohol Craving NCT01631630 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Ketamine for Depression and Alcohol Dependence NCT01551329 | Yale University | Phase 1 |
| Completed | Changing the Vulnerable Brain: A Neuromodulation Study in Alcohol Dependence NCT02557815 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | Phase 3 |
| Completed | Validation of a Short Questionnaire (SSI) for Sleep Disorders in Patients With Alcohol NCT04007042 | Centre Hospitalier Universitaire de Nīmes | — |
| Completed | Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence NCT01534494 | University of New Mexico | Phase 2 |
| Completed | New Treatment for Alcohol and Nicotine Dependence NCT01182766 | University of Virginia | Phase 2 / Phase 3 |
| Completed | Doxazosin an a1 Antagonist for Alcohol Dependence NCT01437046 | Brown University | EARLY_Phase 1 |
| Completed | Brain Derived Neurotrophic Factor Serum Levels Evolution During the Six Months After Alcohol Withdrawal NCT01491347 | Centre Hospitalier Esquirol | — |
| Completed | Incubation of Alcohol Craving During Abstinence NCT01991704 | National Institute on Drug Dependence, China | — |
| Completed | Development and Testing of Adolescent Twelve-Step Facilitation NCT01449981 | Massachusetts General Hospital | N/A |
| Completed | Chronic Alcohol, Stress Inflammatory Response and Relapse Risk NCT02193204 | Yale University | N/A |
| Completed | Treatment Strategy for Alcohol Use Disorders in Veterans With TBI NCT01342549 | VA Office of Research and Development | Phase 3 |
| Completed | Transcranial Direct Current Stimulation Over Dorsolateral Prefrontal Cortex in Alcoholism NCT01330394 | Federal University of Espirito Santo | Phase 2 |
| Completed | Varenicline Treatment for Active Alcoholic Smokers NCT01347112 | Mayo Clinic | Phase 2 / Phase 3 |
| Completed | Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders NCT01338506 | Medical University of South Carolina | N/A |
| Completed | Aripiprazole Effects on Alcohol Drinking and Craving NCT01292057 | Medical University of South Carolina | Phase 3 |
| Completed | Baclofen for the Treatment of Alcohol Dependence NCT01266655 | Charite University, Berlin, Germany | Phase 2 / Phase 3 |
| Completed | Alcohol Counseling for Telephone Quitline Callers NCT01120080 | Yale University | Phase 1 / Phase 2 |
| Completed | Dutasteride for the Reduction of Alcohol Use in Male Drinkers NCT01262287 | UConn Health | Phase 4 |
| Completed | Ondansetron, Alcohol Use, and Alcohol-Related Symptoms In HIV+ Persons NCT01254877 | Johns Hopkins University | Phase 2 |
| Completed | Electrophysiological Correlates of Emotional and Crossmodal Stimuli Processing Among Alcohol-dependent Partici NCT01633905 | University Hospital, Lille | — |
| Completed | A Study of Brain Receptor Occupancy in Healthy Subjects NCT01232439 | Eli Lilly and Company | Phase 1 |
| Completed | Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^ NCT01227980 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Efficacy Trial of Warrior Check-Up NCT01128140 | University of Washington | Phase 2 |
| Completed | Pilot Study of Text Message Brief Interventions for Problem Drinkers NCT01180829 | Centre for Addiction and Mental Health | N/A |
| Completed | A Study of Quetiapine and Mirtazapine for the Treatment of Alcohol Dependency NCT01165541 | Dartmouth-Hitchcock Medical Center | Phase 2 |
| Completed | HBPL Study of the Impact of the NK1 Antagonist Aprepitant NCT01176591 | University of Pennsylvania | Phase 2 |
| Terminated | Pilot Study of Depot NTX in Homeless Veterans NCT01155869 | US Department of Veterans Affairs | Phase 4 |
| Completed | Alcohol Pharmacotherapy for HIV+ Prisoners NCT01077310 | Yale University | N/A |
| Completed | Gabapentin for Abstinence Initiation in Alcohol Dependence NCT01141049 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Completed | Impact of Exercise and Affirmations (IntenSati) on Addiction-related Cognitive and Psychosocial Deficits NCT01171677 | NYU Langone Health | N/A |
| Unknown | Topiramate for Hospitalized Patients With Alcoholism: a 12-week Study NCT01135602 | Chiang Mai University | Phase 4 |
| Completed | Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol Craving NCT01151813 | University of Pennsylvania | Phase 2 |
| Completed | Efficacy of Topiramate for Hospitalized Patients With Alcoholism NCT01145677 | Chiang Mai University | Phase 2 / Phase 3 |
| Completed | Impact of Group Motivational Interviewing and In-Home-Messaging-Devices for Dually Diagnosed Veterans NCT00706901 | VA Office of Research and Development | N/A |
| Completed | Screening and Brief Intervention in the ED Among Mexican-origin Young Adults NCT02056535 | Public Health Institute, California | Phase 2 |
| Completed | Helping Problem Drinkers on the Internet NCT01114919 | Centre for Addiction and Mental Health | N/A |
| Completed | Cerebral Hemodynamics With rTMS in Alcohol Dependence NCT02446067 | Central Institute of Psychiatry, Ranchi, India | N/A |
| Completed | Effects of Sulfasalazine on BOLD Response to Alcohol Cues NCT01312129 | The Mind Research Network | N/A |
| Unknown | Varenicline for Alcohol Dependence NCT01071187 | Johannes Gutenberg University Mainz | Phase 2 |
| Completed | Treatment of Alcohol Dependence and Comorbid Bipolar Disorder NCT01015586 | Medical University of South Carolina | Phase 4 |
| Completed | Transcranial Magnetic Stimulation in Alcohol Use Disorder NCT02862093 | Catholic University of the Sacred Heart | N/A |
| Completed | Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence NCT01055171 | Medical University of South Carolina | Phase 2 |
| Completed | Sweet Preference and Alcohol Craving NCT01296646 | University of North Carolina, Chapel Hill | Phase 2 |
| Completed | CRF1 Antagonist GSK561679 in Alcoholism NCT01187511 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Baclofen as Add-On to Standard Treatment of Alcohol- Dependent Patients NCT01002105 | Sha'ar Menashe Mental Health Center | Phase 4 |
| Completed | Alcohol Drinking as a Vital Sign NCT01135654 | Kaiser Permanente | N/A |
| Completed | Identifying Multiple Mechanisms of Change in Alcoholism Treatment NCT01168960 | State University of New York at Buffalo | Phase 4 |
| Completed | A Controlled Trial of Extended Brief Interventions in Alcohol Dependent Patients NCT01060397 | Southport and Ormskirk Hospital NHS Trust | N/A |
| Completed | ALK33-005: A Study of ALKS33 (RDC-0313) in Adults With Alcohol Dependence NCT00981617 | Alkermes, Inc. | Phase 2 |
| Completed | Mindfulness Meditation for Health NCT01056484 | University of Wisconsin, Madison | Phase 2 |
| Completed | Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse NCT00585780 | Yale University | Phase 1 / Phase 2 |
| Completed | Disulfiram Combined With Lorazepam for Alcohol Dependence and Anxiety Disorder NCT00721526 | University of New Mexico | Phase 4 |
| Completed | Anti-craving Efficacy of Right and Left Prefrontal High Frequency Repetitive Transcranial Magnetic Stimulation NCT01093716 | Central Institute of Psychiatry, Ranchi, India | N/A |
| Completed | Duloxetine Versus Pregabalin for Alcohol Dependence NCT00929344 | The Scripps Research Institute | Phase 2 |
| Completed | VIVITROL as a Treatment for Cocaine and Alcohol Dependence NCT00777062 | University of Pennsylvania | Phase 2 |
| Completed | Imaging of Cannabinoid 1 Receptors Using [11C]OMAR and PET NCT01719497 | Yale University | — |
| Completed | Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism NCT00920829 | Medical University of South Carolina | Phase 4 |
| Withdrawn | Effects of GSK598809 on Brain Activation in Abstinent Alcoholics NCT00908206 | GlaxoSmithKline | Phase 1 |
| Terminated | Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism NCT00862563 | Boston Medical Center | Phase 2 |
| Completed | The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD NCT00896038 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | The MEADOW PROJECT (Mending the Effects of Alcohol and Depression on Women) and The Bridge Program (Connecting NCT00851669 | University of Rochester | Phase 2 |
| Completed | Does Varenicline Influence Alcohol Consumption in Alcohol Dependent Individuals? NCT00846859 | Sahlgrenska University Hospital | Phase 2 |
| Completed | Efficacy of Nalmefene in Patients With Alcohol Dependence NCT00812461 | H. Lundbeck A/S | Phase 3 |
| Completed | Safety and Efficacy of Nalmefene in Patients With Alcohol Dependence NCT00811941 | H. Lundbeck A/S | Phase 3 |
| Terminated | A Study of MK0594 in Patients With Alcohol Dependence (0594-020) NCT00835718 | Vyne Therapeutics Inc. | Phase 2 |
| Completed | Cognitive Behavioral Treatment to Reduce Alcohol Use Among HIV-Infected Kenyans NCT00792519 | Brown University | Phase 1 |
| Completed | Computer-Based Alcohol Use Disorder Recovery System NCT01003119 | University of Wisconsin, Madison | N/A |
| Completed | Pharmacogenetic Response to Naltrexone For Alcohol Dependence NCT00831272 | David Oslin | Phase 4 |
| Completed | Topiramate to Aid Smoking Cessation in Alcohol Dependent Men NCT00802412 | VA Office of Research and Development | Phase 2 |
| Completed | Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD). NCT00744055 | Yale University | Phase 3 |
| Completed | Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol Dependence NCT00923923 | Yale University | N/A |
| Completed | Efficacy of Nalmefene in Patients With Alcohol Dependence NCT00811720 | H. Lundbeck A/S | Phase 3 |
| Completed | A Study in the Treatment of Alcohol Dependence. NCT00805441 | Eli Lilly and Company | Phase 2 |
| Completed | ALK33-001: A Study of RDC-0313 Administered to Healthy Adults NCT00800319 | Alkermes, Inc. | Phase 1 |
| Completed | Study of the Effects of Motivational Enhancement Therapy on Alcohol Use in Chronic Hepatitis C Patients NCT00596960 | US Department of Veterans Affairs | N/A |
| Completed | ALK29-002: A Study of Baclofen Formulations in Healthy Adults NCT00802035 | Alkermes, Inc. | Phase 1 |
| Completed | A Study for the Treatment of Alcohol Dependence NCT00804570 | Eli Lilly and Company | Phase 2 |
| Completed | Effect of Varenicline on Reactivity to Smoking and Drinking Cues NCT00873535 | Centre for Addiction and Mental Health | N/A |
| Completed | Disseminating Organizational SBI Services at Trauma Centers NCT00607620 | University of Washington | N/A |
| Completed | Community Reinforcement and Family Training (CRAFT) for Treatment-resistant Individuals With Alcohol Use Disor NCT02112396 | University of Luebeck | N/A |
| Completed | Varenicline Treatment in Alcohol and Nicotine Dependent Patients With Schizophrenia NCT00727103 | State University of New York - Upstate Medical University | Phase 4 |
| Completed | Mechanisms of Change, Motivation, and Treatment Outcome in Alcohol Dependence - Posttraumatic Stress Disorder NCT01409707 | University of Mississippi Medical Center | N/A |
| Completed | Endophenotyping With Functional Magnetic Resonance Imaging (fMRI) NCT01503931 | Charite University, Berlin, Germany | — |
| Completed | The Effect of Naltrexone on Alcohol Craving and on Brain Activity During Alcohol Infusion NCT00667771 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | EARLY_Phase 1 |
| Completed | An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence NCT00667875 | Medical University of South Carolina | Phase 2 |
| Completed | Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking NCT00665249 | Northwell Health | N/A |
| Completed | Modification of Cognitive Processing Therapy (CPT-C) for PTSD and Alcohol Dependence NCT00639288 | Yale University | Phase 2 / Phase 3 |
| Completed | Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial NCT00619255 | University of Washington | N/A |
| Withdrawn | Couples-based Behavioral Psychotherapy for Male Patients With Posttraumatic Stress Disorder and Alcohol Depend NCT00622921 | Yale University | Phase 2 / Phase 3 |
| Completed | Aripiprazole and Topiramate on Free-Choice Alcohol Use NCT00884884 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 / Phase 3 |
| Completed | Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder NCT00572117 | Stanford University | Phase 4 |
| Completed | Stress, Hypothalamic-pituitary-adrenal (HPA) Dysfunction, and Relapse in Alcoholism NCT00744588 | University of Texas Southwestern Medical Center | — |
| Completed | Mecamylamine for the Treatment of Patients With Depression and Alcohol Dependence NCT00563797 | Yale University | Phase 3 |
| Completed | A Randomized Clinical Trial of Alcohol Care Management NCT00419315 | US Department of Veterans Affairs | Phase 4 |
| Completed | ALK21-018: Effects of Medisorb® Naltrexone (VIVITROL®) on Alcohol Craving in Treatment-seeking, Alcohol-depend NCT00511836 | Alkermes, Inc. | Phase 4 |
| Completed | Combination of Naltrexone and Baclofen for Alcohol Dependence:A Pilot Study. NCT00614328 | University of North Carolina, Chapel Hill | Phase 1 |
| Completed | Extended-release Naltrexone for Alcohol Dependence in Primary Care NCT00620750 | NYU Langone Health | Phase 4 |
| Completed | Facilitating Aftercare for Alcohol Detox Patients NCT00513708 | State University of New York at Buffalo | N/A |
| Withdrawn | Norepinephrine Transporter Imaging in Addiction Disorders NCT01719458 | Yale University | — |
| Completed | ALK21-014: Efficacy and Safety of Medisorb® Naltrexone (VIVITROL®) After Enforced Abstinence NCT00501631 | Alkermes, Inc. | Phase 3 |
| Completed | Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence NCT01014533 | Dr. Kirk Brower | N/A |
| Completed | Efficacy and Safety of Levetiracetam in Prevention of Alcohol Relapse in Recently Detoxified Alcohol Dependent NCT00758277 | Charite University, Berlin, Germany | Phase 3 |
| Completed | Injectable Naltrexone Treatment of Alcohol Dependence in Serious Mental Illness (SMI) NCT00453609 | State University of New York - Upstate Medical University | Phase 4 |
| Completed | Acamprosate vs. Placebo in Bipolar Alcoholics NCT00466661 | Medical University of South Carolina | Phase 4 |
| Withdrawn | Topiramate for Treatment of Patients With Borderline Personality Disorder and Alcohol Dependence NCT00463775 | Elizabeth Ralevski | Phase 3 |
| Completed | Quetiapine for Bipolar Disorder and Alcohol Dependence NCT00457197 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | A Randomized Controlled Trial of Structured Stepped-care Intervention for Psychiatric Comorbidity NCT01941693 | South West Sydney Local Health District | N/A |
| Completed | Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism NCT00452543 | Massachusetts General Hospital | Phase 4 |
| Unknown | Neurocognitive Functioning Following The PROMETA® Treatment Protocol In Subjects With Alcohol Dependence NCT00570388 | Institute of Addiction Medicine | N/A |
| Unknown | Novel Pharmacotherapy for Dual Dependence NCT00448825 | Bankole Johnson | Phase 3 |
| Unknown | Medication and Counseling for Controlled Drinking NCT01115894 | Research Foundation for Mental Hygiene, Inc. | Phase 3 |
| Terminated | Study of Acamprosate in Driving Under the Influence (DUI) Court Participants NCT00425711 | University of Oklahoma | N/A |
| Completed | Ondansetron With Olanzapine for the Treatment of Alcohol Dependence: A Preliminary Clinical Trial NCT00678457 | University of Virginia | Phase 2 |
| Withdrawn | Safety of Acamprosate for Alcohol Dependence in the Elderly: An Open-Label Study (SAFADIE) NCT00655967 | University of New Mexico | Phase 4 |
| Completed | LINK: Aftercare Monitoring Project NCT00265512 | VA Office of Research and Development | N/A |
| Terminated | Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical NCT00461890 | State University of New York - Upstate Medical University | Phase 4 |
| Completed | Treatment With Acamprosate in Patients With Schizophrenia and Comorbid Alcoholism NCT00463346 | Yale University | Phase 3 |
| Completed | Study of Campral (Acamprosate) for Alcohol Dependence in a Family Medicine Clinic NCT00381043 | University of North Carolina, Chapel Hill | Phase 4 |
| Completed | Intensive Intervention for Smokers - 6 NCT00217984 | University of California, San Francisco | N/A |
| Completed | Injectable Versus Oral Naltrexone Treatment of Alcohol Dependence In Serious Mental Illness (SMI) NCT00453804 | State University of New York - Upstate Medical University | Phase 4 |
| Completed | Zonisamide vs. Placebo in the Treatment of Alcohol Dependence NCT00595556 | UConn Health | Phase 4 |
| Completed | Pharmacological Treatment for Alcoholism NCT00382642 | Bankole Johnson | Phase 3 |
| Completed | Optimizing Pharmacotherapy for Bipolar Alcoholics NCT00302133 | University of Miami | Phase 1 / Phase 2 |
| Completed | Open Label Trial of Acamprosate in Bipolar Alcoholics NCT00330486 | Medical University of South Carolina | Phase 1 / Phase 2 |
| Completed | Acamprosate in Alcoholics With Comorbid Anxiety or Depression NCT00330174 | Medical University of South Carolina | Phase 4 |
| Completed | Effectiveness of Naltrexone Versus Placebo to Reduce Craving for Alcohol With Evaluation of Genetic Variabilit NCT00366626 | Medical University of South Carolina | Phase 4 |
| Completed | Addiction Health Evaluation And Disease Management (AHEAD) Study NCT00278447 | Boston Medical Center | Phase 3 |
| Completed | Topiramate for the Treatment of Alcohol Dependent Binge-Eating Disordered Individuals NCT00300742 | University of Virginia | Phase 2 |
| Completed | Effect of LY686017 on Alcohol Craving NCT00310427 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Effects of Omegas 3 and 6 on Alcohol Dependence NCT01211769 | Federal University of São Paulo | Phase 3 |
| Completed | CRAFT Behavior Therapy: Treatment Entry Component NCT00842036 | Treatment Research Institute | Phase 2 |
| Completed | Efficacy and Safety of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Alcohol Dependency in Patients With NCT00114686 | AstraZeneca | Phase 3 |
| Completed | Individualized Treatment Program for Alcohol Problems NCT00298792 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 1 |
| Completed | Prometa Protocol for Alcohol Dependence NCT00262639 | Medical University of South Carolina | Phase 2 / Phase 3 |
| Recruiting | Substance Abuse Pre-Treatment Screening Study NCT00439049 | The University of Texas Health Science Center, Houston | — |
| Completed | Making Alcoholics Anonymous Easier NCT01382316 | Alcohol Research Group | Phase 3 |
| Terminated | Study of Acamprosate to Prevent Alcohol Relapse in Criminal Justice Supervisees NCT00249379 | Virginia Commonwealth University | Phase 4 |
| Completed | Aripiprazole Effects on Alcohol Reactivity and Consumption NCT00183235 | Medical University of South Carolina | Phase 2 |
| Completed | Naltrexone for Bipolar Disorder and Alcohol Dependence NCT00223275 | University of Texas Southwestern Medical Center | Phase 4 |
| Unknown | Enhanced Motivational Interviewing With Alcohol Positive Trauma Patients NCT00280488 | Brown University | Phase 3 |
| Completed | Effectiveness of Naltrexone and/or Ondansetron to Reduce Craving for Alcohol and Drinking NCT00183222 | Medical University of South Carolina | Phase 2 |
| Completed | Efficacy and Tolerability of Baclofen for Alcohol Dependence NCT00877734 | University of North Carolina, Chapel Hill | Phase 2 / Phase 3 |
| Completed | Alcoholism Assessment and Treatment NCT00106093 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | — |
| Completed | Acamprosate to Reduce Symptoms of Alcohol Withdrawal NCT00106106 | National Institutes of Health Clinical Center (CC) | Phase 2 |
| Unknown | Project RAP: Reaching Adolescents for Prevention NCT00183157 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Phase 2 |
| Completed | Motivation in Alcohol Treatment Facilities NCT00424112 | University Medicine Greifswald | — |
| Completed | The iHealth Study in College Students NCT00183131 | Boston Medical Center | Phase 2 |
| Completed | Russia PREVENT (HIV Prevention Partnership in Russian Alcohol Treatment) NCT00183118 | Boston Medical Center | Phase 1 / Phase 2 |
| Completed | Effectiveness of Extended Telephone Monitoring NCT00194103 | University of Pennsylvania | Phase 3 |
| Completed | The Effects of Mirtazapine Versus Placebo on Alcohol Consumption in Male Alcohol High Consumers NCT00874003 | Sahlgrenska University Hospital | Phase 2 |
| Completed | Alcohol Use Disorders in Schizophrenia NCT00280813 | University of Maryland, Baltimore | N/A |
| Completed | Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MI NCT00579267 | University of South Florida | — |
| Completed | Gabapentin Treatment of Alcohol Dependence NCT00391716 | The Scripps Research Institute | Phase 2 |
| Completed | Alcohol and Gender Effects on Stress Circuit Function NCT00226694 | University of Cincinnati | N/A |
| Completed | Contingency Management for Chronic Recidivist Alcohol-Dependent Patients NCT00408161 | UConn Health | N/A |
| Completed | Targeted Naltrexone for Problem Drinkers NCT00369408 | UConn Health | Phase 4 |
| Completed | Combined Treatment for Cocaine-Alcohol Dependence - 1 NCT00218569 | The University of Texas Health Science Center, Houston | Phase 2 |
| Completed | Drug Therapy for Alcohol Dependence in Alaska Natives (Naltrexone/Sertraline) NCT00000451 | Yale University | Phase 2 |
| Completed | Effectiveness of Gabapentin When Used With Naltrexone to Treat Alcohol Dependence Compared to Placebo and Nalt NCT00183196 | Medical University of South Carolina | Phase 3 |
| Completed | Motivational Interviewing for Alcohol-Positive Teens in the Emergency Room NCT00246428 | Brown University | Phase 3 |
| Completed | Outpatient Versus Inpatient Detoxification Program for Alcohol Dependent Patients Seeking Abstinence: The IN/O NCT00226720 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | A New Pharmacotherapy for Alcohol Dependence: Olanzapine NCT00746785 | The Mind Research Network | Phase 3 |
| Completed | ALK21-003EXT: An Extension of Study ALK21-003 (NCT01218958) to Test the Long-term Safety of Medisorb® Naltrexo NCT01218971 | Alkermes, Inc. | Phase 3 |
| Completed | Treatment Settings for Those With an Alcohol Problem NCT02986776 | State University of New York at Buffalo | N/A |
| Completed | Paroxetine for Comorbid Social Anxiety Disorder and Alcoholism NCT00246441 | Medical University of South Carolina | Phase 4 |
| Completed | Network Support for Treatment of Alcohol Dependence NCT00845208 | UConn Health | N/A |
| Completed | Comparative Study of Gamma-hydroxy Butyrate Versus Oxazepam in the Treatment of Alcohol Withdrawal Syndrome NCT02090504 | Catholic University of the Sacred Heart | Phase 4 |
| Completed | A Therapeutic Workplace for Alcohol Dependence NCT00183144 | Johns Hopkins University | Phase 2 |