NCT00457197

Quetiapine for Bipolar Disorder and Alcohol Dependence

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: University of Texas Southwestern Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to find out whether an investigational drug called quetiapine can treat bipolar disorder, improve mood and reduce alcohol use and craving.

Detailed description

The primary aim in the study is to determine if quetiapine treatment is associated with greater reduction in alcohol use than placebo in outpatients with bipolar disorder and alcohol dependence. We will also examine if quetiapine treatment is associated with greater reduction in alcohol craving than placebo in outpatients with bipolar disorder and alcohol dependence and if quetiapine treatment is associated with greater improvement in depressive symptoms than placebo in outpatients with bipolar disorder and alcohol dependence.

Conditions

• Bipolar Disorder
• Alcohol Dependence

Interventions

Type	Name	Description
DRUG	Placebo	Inactive ingredient matching the active medication in appearance.
DRUG	Quetiapine	Quetiapine is an atypical antipsychotic approved for the treatment of schizophrenia, bipolar disorder, and in the XR version along with an SSRI to treat major depressive disorder.

Timeline

• Start date: 2007-03-01
• Primary completion: 2011-07-01
• Completion: 2011-07-01
• First posted: 2007-04-06
• Last updated: 2025-07-25
• Results posted: 2016-01-28

Locations

1 site across 1 country: United States