Bipolar Disorder

1,137 registered clinical trials studyying Bipolar Disorder — 99 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applicatio NCT07444463	Central South University	N/A
Not Yet Recruiting	Enhancing Veteran-Clinical Collaboration in VA PRRCs NCT06898879	VA Office of Research and Development	N/A
Not Yet Recruiting	Functional Magnetic Resonance Imaging Study of Inhibitory Control in Bipolar Disorder and Major Depressive Dis NCT07503275	CHU de Reims	N/A
Not Yet Recruiting	Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT NCT07534475	Medipol University	N/A
Not Yet Recruiting	Emotional Eating, Sleep Quality, Mental State and Metabolic Syndrome NCT07411222	Abant Izzet Baysal University	—
Not Yet Recruiting	Empagliflozin Adjunctive Therapy in Bipolar Depression NCT07472920	University of Sao Paulo	N/A
Recruiting	CBT-CP for Veterans With SMI NCT06758414	VA Office of Research and Development	N/A
Withdrawn	Lifestyle MIND- Feasibility of Wait-list Control NCT06384521	The University of Texas Health Science Center at San Antonio	N/A
Enrolling By Invitation	Mindfulness-Based Therapy for Serious Mental Illness NCT06880796	Butler Hospital	N/A
Recruiting	A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1) NCT07286175	Eli Lilly and Company	Phase 2
Recruiting	Visual Perception in Schizophrenia NCT06911931	University of Rochester	N/A
Recruiting	Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness NCT07316803	Centre hospitalier de Ville-Evrard, France	N/A
Recruiting	Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Tre NCT07479758	Second Affiliated Hospital, School of Medicine, Zhejiang University	—
Enrolling By Invitation	An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE) NCT07217860	Xenon Pharmaceuticals Inc.	Phase 3
Recruiting	A Study of Olanzapine in Participants With Bipolar Disorder. NCT07263191	Boryung Pharmaceutical Co., Ltd	—
Recruiting	A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mi NCT07140913	Bristol-Myers Squibb	Phase 3
Completed	Effectiveness of Traditional Chinese Metacognitive Training (MCT) in Patients With Schizophrenia, Depression, NCT07051746	ZI-YU LIN	N/A
Not Yet Recruiting	NeuroPsyBiT-BD Omics: Genomic & Epigenomic Biobank of Bipolar Disorder NCT07173842	Selçuk State Hospital	—
Not Yet Recruiting	Approaches For ThE pRioritization of Patients in priMAry Care Post-COVID To Reduce Health Inequities (AFTERMAT NCT05823805	Unity Health Toronto	N/A
Recruiting	A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Re NCT07105111	Neurocrine Biosciences	Phase 4
Recruiting	A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disord NCT07172516	Xenon Pharmaceuticals Inc.	Phase 3
Recruiting	Reduction of Anticholinergic Medications Among Persons With Schizophrenia or Other Psychiatric Disorders NCT07043803	University of Pittsburgh	N/A
Not Yet Recruiting	Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling NCT06748950	Stanford University	N/A
Active Not Recruiting	The Combination of Pharmacotherapy and Cognitive Behavioral Psychotherapy Under the Recovery Perspective. NCT06993662	Rakitzi, Stavroula	Phase 1
Recruiting	Mindfulness Psychoeducation for Bipolar Disorder Caregivers' Mindfulness, Burden, Quality of Life and Resilien NCT06983834	Pamukkale University	N/A
Recruiting	Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-I NCT06897670	Mayo Clinic	—
Recruiting	Mechanisms of Transcutaneous Auricular Vagus Nerve Stimulation in Depression NCT07022171	Max-Planck-Institute of Psychiatry	N/A
Recruiting	Enhancing Rehabilitation for Veterans With Serious Mental Illness NCT06586164	VA Office of Research and Development	N/A
Recruiting	Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depress NCT06507787	Alcediag	N/A
Not Yet Recruiting	Obstructive Sleep Apnea Treatment in Serious Mental Illness NCT05457127	University of California, San Diego	N/A
Recruiting	Efficacy and Safety of Task-activated rTMS in Improving Cognitive Function in Patients With Bipolar Disorder NCT06782763	First Affiliated Hospital of Zhejiang University	N/A
Active Not Recruiting	A Future Thinking Intervention for Comorbid Tobacco Use Disorder and Bipolar Disorder NCT06609902	Massachusetts General Hospital	N/A
Recruiting	Healthy Lifestyles in Bipolar Disorder: Bay Area Study NCT06555406	University of California, Berkeley	N/A
Recruiting	Narrative Enhancement and Cognitive Therapy for Self-Stigma in Youth NCT06672562	Centre for Addiction and Mental Health	N/A
Recruiting	A Cohort Study of Disease Prediction Model for High-risk Population With Bipolar Disorder NCT07031661	Shanghai Mental Health Center	—
Not Yet Recruiting	Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Hea NCT06235177	The Essence of Integrative Health and Medicine Practice	EARLY_Phase 1
Recruiting	Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder NCT06274567	Massachusetts General Hospital	N/A
Completed	Clocks in Sync - Circadian Rhythm and Bipolar Mania NCT06504342	Ottawa Hospital Research Institute	N/A
Recruiting	mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders NCT06204705	VA Office of Research and Development	—
Not Yet Recruiting	Effect of Esterogen Receptor Modulator on Gene in Bipolar Diseas NCT06580535	Assiut University	—
Recruiting	Taking Action for College Students NCT06700902	Temple University	N/A
Not Yet Recruiting	A Biological Signature for the Early Differential Diagnosis of Psychosis NCT06515522	IRCCS San Raffaele	—
Recruiting	Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD) NCT04080778	Joao L. DeQuevedo	N/A
Recruiting	Physical Exercise for Cognitive Rehabilitation of Patients With Bipolar Affective Disorder NCT06560749	Beny Lafer	N/A
Recruiting	Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder NCT06226025	Leslie Swanson	Phase 2
Recruiting	Personalized Mobile Cognitive Behavioral Therapy Application NCT05699525	Weill Medical College of Cornell University	N/A
Recruiting	Neuro-computational Study of Thymic Fluctuations in Mood Disorders NCT07033923	Centre Hospitalier St Anne	N/A
Recruiting	Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy NCT06529029	Michigan State University	Phase 2 / Phase 3
Completed	Mood Disorders in Multiple Sclerosis Patients NCT06652308	Islamic Azad University, Sanandaj	—
Recruiting	Apathy-related Neurobehavioral Markers of Cognitive Decline in Old-age Bipolar Disorders: Proof-of-concept NCT06914284	Hospital Center Guillaume Régnier	—
Terminated	BHV-7000 Open-Label Extension Bipolar Mania Study NCT06423794	Biohaven Therapeutics Ltd.	Phase 2
Recruiting	Self-compassion and Bipolar Disorder NCT06497868	University Hospital, Strasbourg, France	—
Terminated	Behavioural Activation Therapy and Esketamine for Resistant Depression NCT06431386	The Royal's Institute of Mental Health Research	N/A
Completed	Brain Small Chain Fatty Acid Metabolism in Bipolar Disorder: Ketones NCT06335875	University of Michigan	N/A
Not Yet Recruiting	A Close Examination of Patient Experiences in Bipolar Disorder Clinical Trials NCT05891639	Power Life Sciences Inc.	—
Completed	BHV-7000 Acute Treatment of Bipolar Mania NCT06419582	Biohaven Therapeutics Ltd.	Phase 2 / Phase 3
Recruiting	Neurofeedback for Bipolar Disorder NCT05802446	Assistance Publique - Hôpitaux de Paris	N/A
Recruiting	Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression NCT06363981	Jakub Antczak	N/A
Recruiting	Theta-Burst Stimulation for Bipolar Depression NCT06370988	Centre for Addiction and Mental Health	N/A
Recruiting	Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Dep NCT06371352	Jakub Antczak	N/A
Recruiting	ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder NCT06365021	Beny Lafer	N/A
Recruiting	Seeing the Light: Early Intervention in People at Risk for Bipolar Disorder NCT06282250	Geestelijke Gezondheidszorg Eindhoven (GGzE)	N/A
Recruiting	Honest Open Proud for Psychotic and Bipolar Disorder in Norway NCT06384755	Oslo University Hospital	N/A
Recruiting	Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China NCT06424613	Peking University	—
Withdrawn	Sleep Quality, Cognitive Performance, and Computerized Cognitive Training NCT06328140	George West Mental Health Foundation d/b/a Skyland Trail	—
Recruiting	Stabilizing Mood and Sleep With Blue Blocking Eyewear in Bipolar Disorder NCT06271304	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	N/A
Recruiting	A Study to Evaluate the Efficacy of VR for Bipolar Disorder NCT06399523	Shanghai Mental Health Center	N/A
Active Not Recruiting	Studying the Health of Asians to Advance Knowledge, Treatments, and Interventions for Depression NCT06002204	University of Texas Southwestern Medical Center	—
Recruiting	Getting Out of the House: Using Behavioral Activation to Increase Community Participation NCT06336616	Temple University	N/A
Active Not Recruiting	REWRITALIZE Your Recovery - Evaluation of a Creative Writing Group Intervention NCT06251908	Amager Hospital	N/A
Recruiting	Enhanced Coordinated Specialty Care for Early Psychosis NCT06071858	Mclean Hospital	N/A
Recruiting	Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder NCT06373016	Stony Brook University	N/A
Recruiting	Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Au NCT06229210	Intra-Cellular Therapies, Inc.	Phase 3
Unknown	Predictors of Intravenous Ketamine Response in TRD NCT05625555	Abraham Nunes	Phase 3
Recruiting	Examining Neurobiological Mechanisms Underlying the Therapeutic Effect of the Ketogenic Diet in Bipolar Disord NCT06081426	University of Pittsburgh	N/A
Not Yet Recruiting	Norwegian Adult Mental Health Registry NCT06115200	Helse Stavanger HF	—
Completed	The CARE (Collaborative Adolescent Running Experience) Project NCT05837351	University of Michigan	N/A
Completed	Predictors of Quality of Life in Bipolar Disorder NCT06101212	Kubra TOHUMCU	—
Active Not Recruiting	Bipolar Disorder Integrative Staging: Incorporating Biomarkers Into Progression Across Stages NCT07343739	ASST Fatebenefratelli Sacco	—
Recruiting	NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar NCT05669703	National Institute of Mental Health (NIMH)	—
Completed	Bipolar Disorder Measures in Clinical Care NCT05300919	University of Cincinnati	N/A
Recruiting	App and Body Fat Scale in the Management of Overweight Patients NCT05866107	Capital Medical University	N/A
Recruiting	Cannabidiol for Bipolar Depression (CBD-BD) NCT05867849	University of British Columbia	Phase 3
Recruiting	Effectiveness of a Pragmatic, Metabolic Care Clinic for Patients With Severe Mental Illness - The Meta Care Cl NCT06624462	Bjorn H. Ebdrup	N/A
Completed	Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Di NCT06041646	BioXcel Therapeutics Inc	Phase 4
Not Yet Recruiting	Premorbid Personality Profile of Patients With Cognitive and Behavioral Disorders NCT06059313	Nantes University Hospital	—
Terminated	Alexithymia Intervention for Suicide NCT05724953	VA Office of Research and Development	Phase 1
Recruiting	Exercise Therapy in Mental Disorders-study NCT06313918	Haukeland University Hospital	N/A
Recruiting	Effect of Nutritional Counseling on Anthropometry and Biomarkers in Patients Diagnosed With Schizophrenia/Psyc NCT06197048	Vestre Viken Hospital Trust	N/A
Withdrawn	Pilot Study 1: Efficacy and Safety of Sublingual Dexmedetomidine (BXCL501) for the Treatment of Agitation in t NCT05974527	Brigham and Women's Hospital	Phase 4
Unknown	The Effect of Dulaglutide as an Adjuvant Therapy on Cognitive Function in Bipolar Disorder Patients With Obesi NCT06331286	First Affiliated Hospital of Zhejiang University	N/A
Suspended	CBT for Problematic Impulsive Behaviours in Bipolar Disorder: A Case Series / CBT-PIB NCT06129500	University of Exeter	N/A
Completed	Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness NCT05725785	University of Washington	N/A
Withdrawn	Inositol for Comorbid Anxiety in Children and Adolescents With Bipolar Disorder NCT02811133	Ronald M. Glick, MD	Phase 1 / Phase 2
Unknown	Culturally Adapted Psychoeducation (CaPE) for Bipolar Disorders in Nigeria NCT05721196	Nottingham Trent University	N/A
Recruiting	Acute Alcohol Response In Bipolar Disorder: a Longitudinal Alcohol Administration/fMRI Study NCT05838274	University of Texas at Austin	N/A
Unknown	Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bip NCT06093451	Temple University	Phase 4
Recruiting	Critical Time Intervention-Peer Support NCT05945277	Lisbon Institute of Global Mental Health - LIGMH	N/A
Completed	Music Therapy to Reduce Anxiety in Community-Dwelling Individuals With Severe Mental Illness NCT06315049	Universitat Politècnica de València	N/A
Completed	Contingency Management for Problematic Behavior Reduction in the Community NCT06486584	Laureate Institute for Brain Research, Inc.	N/A
Completed	Comparison of Physical Fitness, Physical Activity Level in Patients With Bipolar Disorder and Schizophrenia NCT05936983	Yeditepe University	—
Recruiting	Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder NCT05457465	Mclean Hospital	Phase 2
Terminated	Time-Restricted Eating and Bipolar Disorder NCT06105294	University of California, Berkeley	N/A
Unknown	Adapting the Tumor Board Model for Mental Illness and Cancer NCT05837598	Massachusetts General Hospital	N/A
Active Not Recruiting	EPI-MINN: Targeting Cognition and Motivation - National NCT05877716	University of Minnesota	N/A
Completed	Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tar NCT05859698	Neurocrine Biosciences	Phase 4
Terminated	Music Therapy Advocacy Recording Intervention (MTAR) on Internalized Stigma NCT05723328	Hackensack Meridian Health	N/A
Completed	Bipolar Transcranial Alternating Current Stimulation (tACS) NCT05480124	University of Michigan	N/A
Recruiting	The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects NCT05786066	Yale University	Phase 2
Recruiting	COMpassion for Psychiatric Disorders And Self-Stigma NCT05698589	University Hospital, Strasbourg, France	N/A
Unknown	Functional Remediation for Older Adults With Bipolar Disorder NCT05186337	Consorcio Centro de Investigación Biomédica en Red (CIBER)	N/A
Enrolling By Invitation	Observation of Clozapine Treatment Safety in Bipolar Disorder. NCT06011460	Medical University of Gdansk	—
Enrolling By Invitation	Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness NCT05703412	Butler Hospital	N/A
Completed	Oral Contraceptives for Treating Premenstrual Dysphoric Disorder in Bipolar Disorder NCT05098574	St. Joseph's Healthcare Hamilton	Phase 2
Completed	Effects of Altitude-like Cognition Training on Neuroplasticity and Cognitive Functions NCT06121206	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	N/A
Unknown	Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness NCT05705063	Stanford University	N/A
Unknown	MOrphometric MRI Analysis of Cortical Sulci: Development of NEurodevelopmental Biomarkers of Bipolar Disorder. NCT05674019	Assistance Publique Hopitaux De Marseille	N/A
Active Not Recruiting	AMIloride for the Treatment of Nephrogenic Diabetes Insipidus for Patients With Bipolar Disorder Treated With NCT05044611	Assistance Publique - Hôpitaux de Paris	Phase 4
Unknown	Clinical Evaluation of the Antidepressant Effect of the Use of Probiotics in Bipolar Disorder NCT05762887	University of Sao Paulo	N/A
Completed	Causal Lesion Network Guided Treatment of Bipolar Mania With Transcranial Electrical Stimulation NCT05445466	Beth Israel Deaconess Medical Center	N/A
Unknown	Psychiatric Co-morbidities and Socio-demographic Characteristics in Patients With Idiopathic Hypersomnia NCT05778721	University Hospital, Toulouse	—
Recruiting	Basal Plasma Lithium Levels and Suicidal Events NCT05409794	University Hospital, Montpellier	—
Recruiting	Nursing Care of Bipolar Patients With Sleeping Disorders Using Luminotherapy and /or Psychoeducation Program ( NCT04917419	Centre Hospitalier Henri Laborit	N/A
Completed	The Effect of Acceptance and Commitment of Bipolar Disorder Patients NCT06113887	University of Gaziantep	N/A
Recruiting	Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Ment NCT05491538	VA Office of Research and Development	N/A
Recruiting	Pragmatic Patient-oriented Extension Study of Dialectical Behavior Therapy Booster Sessions for Youth With and NCT05627492	Centre for Addiction and Mental Health	N/A
Recruiting	Evaluation of Efficiency of One Day Patient/Caregiver Psychoeducation on the Caregiver's Burden NCT05178966	University Hospital, Montpellier	N/A
Active Not Recruiting	Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD) NCT05172271	National Institute of Mental Health (NIMH)	N/A
Unknown	Biomarkers of ANTidepressant RESponse and Development Risk of Bipolar Disorder NCT05568823	Assistance Publique Hopitaux De Marseille	N/A
Suspended	Braining- Aerobic Physical Activity as Add on Treatment in Bipolar Depression NCT05340686	Region Stockholm	N/A
Completed	Effect of Immersive Virtual Reality-based Cognitive Remediation in Patients With Mood - or Psychosis Spectrum NCT06038955	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	N/A
Completed	Acceptance and Commitment Therapy Based Psychoeducation, Meaning of Life and Coping Skills in Bipolar Disorder NCT06131866	Kubra TOHUMCU	N/A
Completed	Efficacy of Acceptance and Commitment Therapy on Impulsivity and Suicidality Among Clients With Bipolar Disord NCT05693389	Alexandria University	N/A
Completed	Ottawa Sunglasses at Night for Mania Study NCT05206747	Ottawa Hospital Research Institute	N/A
Completed	Neuronavigation rTMS to Improve Depressive Episodes of Bipolar Disorder in Adolescent NCT05929183	First Affiliated Hospital of Zhejiang University	N/A
Unknown	Multi-factor Model Constraction for Early Warning and Diagnosis of MDD NCT05529576	Shanghai Mental Health Center	Phase 4
Completed	Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression NCT05339074	Joshua Rosenblat	Phase 2
Completed	Transcranial Photobiomodulation for Executive Function in Bipolar Disorder NCT05408637	Paolo Cassano	Phase 2
Unknown	A Study of Dayingpian Treating Bipolar Disorder NCT05247593	Shanghai Mental Health Center	—
Completed	Mobile Observation Of Depression NCT05815459	Emteq Ltd	—
Unknown	Bipolar Efficacy Biomarkers for rTMS NCT05393648	University of California, San Diego	N/A
Completed	Ketamine for Treatment-Resistant Bipolar Disorder NCT05004896	Joshua Rosenblat	Phase 2
Recruiting	Children's Bipolar Network Treatment Trial I NCT05427123	University of California, Los Angeles	—
Unknown	Motivational Interviewing in Patients With Bipolar Disorder NCT05428241	Pamukkale University	N/A
Completed	Clinical Validation Study for EDIT-B Test: an Aid for Differential Diagnosis of Bipolar Disorder, Based on RNA NCT05603819	Alcediag	—
Completed	CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies NCT05127837	University of Washington	N/A
Recruiting	Culturally Adapted Psychoeducation for Bipolar Disorder in a Low-resource Setting: A Randomized Controlled Tri NCT05223959	Pakistan Institute of Living and Learning	N/A
Completed	A Study of JNJ-55308942 in the Treatment of Bipolar Depression NCT05328297	Janssen Pharmaceutica N.V., Belgium	Phase 2
Completed	Lithium Versus Anticonvulsants and the Risk of Physical Disorders NCT06005155	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	—
Completed	Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study NCT05380583	Mclean Hospital	N/A
Recruiting	Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient NCT06182787	Sheba Medical Center	—
Completed	Evaluating the Hypothesized Mechanism of Action of N-acetylcysteine for Bipolar Disorder NCT05340504	Medical University of South Carolina	Phase 2
Completed	Vitamin D for Cognition in Bipolar Disorder NCT05357859	Taipei City Hospital	N/A
Unknown	Effect of Probiotic vs Placebo on Cognition Outcomes in Patients With Bipolar Disorder NCT05954598	First Affiliated Hospital of Zhejiang University	N/A
Unknown	Decline in Renal Concentration Ability in Lithium Treated Patients NCT05307042	Radboud University Medical Center	—
Unknown	Oxygenating the Brain With Laser Therapy NCT05354895	University of Texas at Austin	N/A
Completed	Transcranial Direct Current Stimulation Therapy for Bipolar Depression NCT05436613	University of East London	N/A
Completed	Can Neural Network Instability in Schizophrenia be Improved With a Very Low Carbohydrate Ketogenic Diet? NCT05268809	Northern California Institute of Research and Education	N/A
Completed	Group-based Psychoeducation for Relatives of Patients With Bipolar Disorder, a Randomized Controlled Trial NCT06176001	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	N/A
Unknown	Sleep, Obesity and Mental Disease - Biological Markers for the Evaluation of Circadian Rhythmicity NCT05413486	Esbjerg Hospital - University Hospital of Southern Denmark	—
Completed	Investigation of the Effects of Family-Focused Therapy in the Early Period of Bipolar Disorder and Psychotic D NCT05809193	Dokuz Eylul University	N/A
Completed	Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily NCT05317481	Yale University	N/A
Completed	Examining the Effect of EEG-guided Theta Burst Stimulation in Bipolar Disorder NCT05179785	Mary Phillips, MD MD (Cantab)	N/A
Completed	Medication Reviews in Severe Mental Illness NCT05243160	Psychiatric Research Unit, Region Zealand, Denmark	N/A
Recruiting	Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders NCT05064319	Medical University of South Carolina	Phase 2
Unknown	Multimodal Biomarkers of Electroconvulsive Therapy in Severe and Treatment-resistant Depression NCT05463562	Max-Planck-Institute of Psychiatry	—
Active Not Recruiting	Metacognitive Training With Bipolar Disorder Patients. NCT04447807	University of Sao Paulo	N/A
Active Not Recruiting	Effectiveness RCT of Customized Adherence Enhancement NCT04622150	Case Western Reserve University	N/A
Completed	Effects of Low Dose Aspirin in Bipolar Disorder (The A-Bipolar RCT) NCT05035316	Lars Vedel Kessing	Phase 2
Terminated	Study of Bipolar Disorders and Retinal Electrophysiological Markers NCT05161546	Centre Psychothérapique de Nancy	N/A
Completed	Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on NCT05206734	Momentum Data	—
Active Not Recruiting	Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety NCT05157386	Region Stockholm	—
Recruiting	Three-level Model of DBT-informed Care for Youth With and/or at Familial Risk for Bipolar Disorder (DB3) NCT05153369	Centre for Addiction and Mental Health	N/A
Recruiting	Dialectical Behavior Therapy for Youth With and/or at Familial Risk for Bipolar Disorder NCT05153382	Centre for Addiction and Mental Health	N/A
Active Not Recruiting	Investigation of Factors Associated With Preserved Cognitive Function in Bipolar Disorder NCT04454073	St. Olavs Hospital	—
Recruiting	Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease NCT04946916	Hôpital le Vinatier	N/A
Completed	Synaptic Imaging and Network Activity in Treatment Resistant Depression NCT05870501	King's College London	N/A
Completed	Mobile Self-Tracking of Mental Health NCT05023252	VA Office of Research and Development	N/A
Unknown	Brain Insulin Resistance in Mood Disorders NCT03915613	University Health Network, Toronto	Phase 1 / Phase 2
Completed	Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings NCT05030272	Wake Forest University Health Sciences	N/A
Completed	Brain Stimulation and Cognitive Training - Efficacy NCT05111548	University of Michigan	N/A
Terminated	Effects of Cannabis on Cognition and Endocannabinoid Levels in Bipolar Disorder Patients and Healthy Volunteer NCT04231643	University of California, San Diego	EARLY_Phase 1
Recruiting	Early Intervention for Youth at High Risk for Bipolar Disorder NCT04815239	University of Pittsburgh	N/A
Unknown	Resting State Electroencephalogram for Psychotic Disorders NCT05065489	Central South University	—
Recruiting	Time and Virtual Reality in Schizophrenia and Bipolar Disorder NCT04432116	Institut National de la Santé Et de la Recherche Médicale, France	N/A
Unknown	The Effect of Interpersonal Relationships and Social Rhythm Therapy Individuals With Bipolar Disorder NCT05420792	Ege University	N/A
Unknown	Genetics of COVID-19 Risks & Resilience in Bipolar Disorder NCT04972708	Medical University of Graz	—
Completed	Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorder NCT04939818	Novoic Limited	—
Completed	EVALUATION OF BLOOD BIOMARKER-BASED DIAGNOSTIC AID IN OUTPATIENTS SUFFERING FROM DEPRESSION NCT06369805	Les Toises - Psychiatry and Psychotherapy Center	—
Completed	An E-health Psychoeducation for People With Bipolar Disorders NCT06296784	University of Cagliari	N/A
Recruiting	A Study of the Behavioral Variant of Frontotemporal Dementia and Bipolar Disorder: a Neuroimaging and Epigenet NCT06706687	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	N/A
Completed	Familial Risk for Bipolar Disorder and Alcohol Sensitivity NCT04716036	University of Texas at Austin	N/A
Unknown	AKTIBIPO-VALIDATION: A Study to Validate Benefits of Mindpax System in Managing Bipolar Disorder NCT04945057	National Institute of Mental Health, Czech Republic	N/A
Unknown	Naturalistic Study of Ketamine in the Treatment of Depression NCT05249309	Hospital de Clinicas de Porto Alegre	—
Recruiting	Clonidine to Prevent Delirium After Electroconvulsive Therapy. NCT04828226	Insel Gruppe AG, University Hospital Bern	Phase 4
Completed	Effects of Theta Burst Stimulation on the Brain, Behavior, and Clinical Symptoms in Adults With Bipolar Disord NCT04696471	Mary Phillips, MD MD (Cantab)	N/A
Withdrawn	A PET Study With [11C]PBR-28 and an Experimental Medication, Ethyl Eicosapentaenoic Acid NCT04811404	New York State Psychiatric Institute	Phase 4
Completed	Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness NCT04118283	VA Office of Research and Development	N/A
Active Not Recruiting	Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Mood Disorde NCT04675593	Case Western Reserve University	N/A
Completed	Improving Adherence in Adolescents and Young Adults With Bipolar Disorder NCT04348604	Case Western Reserve University	N/A
Terminated	Young People and Illness Management and Recovery (IMR) NCT04778085	University Hospital, Akershus	—
Recruiting	Cognitive Stimulation for Elderly Bipolar Patients NCT04184375	Groupe Hospitalier de la Rochelle Ré Aunis	N/A
Unknown	Reproductive Function in Women With Bipolar Disorder NCT05307848	Central South University	—
Completed	Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders NCT04284267	Massachusetts General Hospital	N/A
Recruiting	Effects of Smartphone-based Treatment for Bipolar Disorder - the Smart Bipolar NCT04230421	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	N/A
Completed	Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery NCT04481737	Dartmouth-Hitchcock Medical Center	N/A
Completed	Psychoeducation for Patients With Bipolar Disorder in Rwanda NCT04671225	University of Aarhus	N/A
Unknown	Identification of Predictive Biomarkers of Mood Relapses in Patients With Bipolar Disorder NCT04703972	University Hospital, Grenoble	N/A
Unknown	A Trial of Functional Remediation in Patients With Bipolar Disorder NCT04577508	Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia	N/A
Unknown	A Descriptive Study on Patients With Bipolar Disorder in Rwanda NCT04674059	University of Aarhus	—
Completed	Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen NCT04684615	National Institute of Mental Health (NIMH)	—
Completed	In-person vs. Remote Wellness Support NCT04526067	The University of Texas Health Science Center at San Antonio	N/A
Completed	Tai Chi/Qigong for Subsyndromal Depression and Cognition in Older Age Bipolar Disorder NCT04450147	Lady Davis Institute	N/A
Completed	Improving Physical Health in Patients With Psychiatric Disorders in General Practice (SOFIA) NCT04618250	University of Copenhagen	N/A
Unknown	Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders NCT05840861	Central South University	—
Completed	Post-Hospital Intervention for Veterans With Comorbid Bipolar and Substance Use Disorders NCT04127604	VA Office of Research and Development	N/A
Recruiting	University of Iowa Interventional Psychiatry Service Patient Registry NCT04480918	Mark Niciu	—
Completed	Intervention for Comorbid Substance Use and Bipolar Disorders NCT04202393	Butler Hospital	N/A
Recruiting	PROSPECTIVE EVALUATION OF BLOOD BIOMARKERS AS AN AID TO DIAGNOSTIC AND TREATMENT IN DRUG-NAIVE PATIENTS WITH D NCT06369792	Les Toises - Psychiatry and Psychotherapy Center	—
Terminated	Brain Circuitry Analysis in Bipolar Disorder NCT05186077	Jennifer Sweet	—
Terminated	Light at Night Study NCT04251234	University of Michigan	N/A
Completed	Impact of Cognitive & Metacognitive Performance on Knowledge Learning When Conducting Therapeutic Education Pr NCT04590300	Centre Hospitalier Charles Perrens, Bordeaux	N/A
Completed	Feasibility Electrical Stimulation Study for Visual Hallucinations NCT04870710	Beth Israel Deaconess Medical Center	N/A
Unknown	Emotional Proactive Processing in Bipolar Disorder NCT04561622	University Hospital, Grenoble	—
Completed	Families With Substance Use and Psychosis: A Pilot Study NCT04284813	Mclean Hospital	N/A
Completed	ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention NCT04298450	Centre for Addiction and Mental Health	N/A
Completed	Bi-REAL - DBT Skills Online Group Intervention for Bipolar Disorder NCT04797351	Julieta Azevedo	N/A
Unknown	Development of a Software Tool, Using Artificial Intelligence, That Integrates Clinical, Biological, Genetic a NCT05801562	IRCCS San Raffaele	—
Unknown	Antidepressant Treatments and Cognitive Function of Bipolar Patients NCT04564573	Tianjin Anding Hospital	—
Completed	Self and Body-esteem in Socio-professional Rehabilitation NCT04436757	Hôpital le Vinatier	N/A
Unknown	A Pilot Randomised Controlled Trial of a Health Champion Intervention NCT04124744	King's College London	N/A
Withdrawn	A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Bipolar Disorder NCT04211428	ProgenaBiome	—
Unknown	Prediction on the Recurrence of Manic and Depressive Episodes in Bipolar Disorder NCT05828056	National Taiwan University Hospital	—
Recruiting	Delivering Electronic Cognitive Behavioural Therapy to Patients With Bipolar Disorder and Residual Depressive NCT04664257	Dr. Nazanin Alavi	N/A
Unknown	Reward and Punishment Sensitivity in Bipolar Disorders NCT04237610	University Hospital, Grenoble	—
Completed	Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder NCT04276883	BioXcel Therapeutics Inc	Phase 3
Completed	12-Month Extension Study of Dialectical Behavior Therapy for Youth With Bipolar Disorder NCT04283188	Sunnybrook Health Sciences Centre	N/A
Completed	The Role of Group Identity on the Community Integration of People With Severe Mental Disorder NCT04304417	Universidad Complutense de Madrid	—
Unknown	Assessment of the Effectiveness of the NECT Program NCT03972735	Hospital Center Alpes-Isère	N/A
Completed	Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - P NCT04269772	Brown University	N/A
Completed	Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis NCT04004416	University of Michigan	Phase 4
Unknown	The Gut Microbiota of Bipolar and Depression NCT03062332	First Affiliated Hospital Xi'an Jiaotong University	—
Completed	MBCT and CBT for Youth at High Risk for Mood and Psychotic Disorders: a Randomized Controlled Trial NCT05070052	University of California, Los Angeles	N/A
Unknown	The CAG Bipolar the CAG Bipolar RCT NCT04229875	Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital	N/A
Active Not Recruiting	Characterizing MyMood Patterns of Use NCT04664374	Sunnybrook Health Sciences Centre	—
Completed	Evaluation of mHealth for Serious Mental Illness NCT04068467	University of Washington	N/A
Completed	Chart Review of Patients Undergoing Ketamine Infusions NCT04209296	Brain and Cognition Discovery Foundation	—
Unknown	A Study of Staccato Loxapine (ADASUVE®) for Inhalation NCT04148963	Lee's Pharmaceutical Limited	Phase 3
Unknown	Functionality and Neurocognition in Patients With Bipolar Disorder After a Physical-exercise Program (FINEXT-B NCT04400630	Bioaraba Health Research Institute	N/A
Recruiting	Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use NCT03601026	Nova Scotia Health Authority	N/A
Completed	Financial Incentives to Improve Medication Adherence NCT04191876	Northwell Health	N/A
Completed	High Intensity Interval Training in Severe Mental Illness NCT03959735	King's College London	N/A
Completed	Treating Self Injurious Behavior: A Novel Brain Stimulation Approach NCT04244786	New York State Psychiatric Institute	N/A
Unknown	Assessment of Cognitive Functions in Bipolar Patients NCT04091828	Assiut University	—
Completed	Dysbiosis in Bipolar Disorder NCT03127176	Hospital Clinic of Barcelona	—
Unknown	Better Sleep in Psychiatric Care - Bipolar NCT04130529	Karolinska Institutet	N/A
Completed	Modeling Mood Course to Detect Markers for Effective Adaptive Interventions- Aim 3 NCT04098497	University of Wisconsin, Madison	Phase 1
Completed	Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People Wit NCT04134871	University of Ulster	N/A
Completed	Novel Pharmacotherapy Approaches in Smokers With Serious Mental Illness NCT04011280	University of California, San Diego	Phase 4
Completed	Acute Alcohol Response In Bipolar Disorder: a fMRI Study NCT04063384	University of Texas at Austin	N/A
Unknown	Open Study of the Neurobiological Effects of Intranasal Ketamine in Children and Adults With Bipolar Disorder NCT05209217	Mclean Hospital	—
Completed	Peer Support Experience for Patients Discharged From Acute Psychiatric Care NCT03404882	University of Alberta	N/A
Completed	Delivering Telemetry-Triggered Educational Content Using MyChart in Mood Disorders NCT03575728	Sunnybrook Health Sciences Centre	N/A
Unknown	Behavioural Activation Therapy for Bipolar Disorder NCT04317859	St. Joseph's Healthcare Hamilton	N/A
Completed	Intervention Targeting Motivational Negative Symptoms NCT04325100	University of Liege	N/A
Unknown	A Genetic Family Cohort Study of Bipolar Disorder in Chinese Han Population NCT04024553	Shanghai Mental Health Center	—
Completed	Trial to Assess the Bioavailability of Quetiapine Versus Seroquel® in Subjects With Schizophrenia or Bipolar D NCT03872596	Otsuka Pharmaceutical Development & Commercialization, Inc.	Phase 1
Recruiting	Attentional Biases, Reward Sensitivity, and Cognitive Control in Adults With Bipolar Disorder NCT03829787	University Hospitals Cleveland Medical Center	—
Completed	Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS) NCT05683431	Rush University Medical Center	N/A
Unknown	Theta-Burst Stimulation in Major Depressive Episodes With Mixed Characteristics. NCT04123301	University of Sao Paulo	N/A
Completed	Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders NCT03622749	Massachusetts General Hospital	N/A
Withdrawn	Suvorexant (Belsomra) for the Treatment of Bipolar Depression With Insomnia NCT03764683	Massachusetts General Hospital	Phase 4
Completed	Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illne NCT03935854	Stanford University	N/A
Unknown	Lithium Therapeutic Drug Monitoring; Once Daily Vs Twice Daily Dosing and the Impact of Kidney Function NCT03811860	Mount Sinai Hospital, Canada	N/A
Completed	The Police-Mental Health Linkage System NCT03740139	Columbia University	N/A
Unknown	EMDR in Adolescents With Bipolar Disorder and History of Trauma NCT03946787	Hospital de Clinicas de Porto Alegre	N/A
Completed	Dissemination and Implementation Field Trial of Dialectical Behavior Therapy for Adolescents With Bipolar Diso NCT03661333	Sunnybrook Health Sciences Centre	N/A
Completed	Augmenting Hospitalization for Serious Mental Illness: Cognitive Bias Modification NCT03509181	Mclean Hospital	N/A
Completed	Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - O NCT03825640	Brown University	N/A
Completed	Study Efficacy of Enhancing Cognitive Reserve in Patients With a First Bipolar Episode NCT06081634	Hospital Clinic of Barcelona	N/A
Terminated	Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And A NCT03768726	Pfizer's Upjohn has merged with Mylan to form Viatris Inc.	Phase 3
Completed	A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women NCT03774641	Johns Hopkins University	—
Unknown	Outcomes Mandate National Integration With Cannabis as Medicine NCT03944447	OMNI Medical Services, LLC	Phase 2
Completed	Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine NCT03367533	Yale University	Phase 1
Completed	Bipolar Disorder and Oxidative Stress Injury Mechanism - Clinical Big Data Analysis Based on Machine Learning NCT03949218	Shanghai Mental Health Center	—
Completed	Technology Enhanced Family Treatment NCT03913013	University of California, Los Angeles	Phase 1 / Phase 2
Completed	Dysbindin-antipsychotics Psychophamarcogenetics: a Mouse-human Translational Study Towards Personalized Health NCT06167577	Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico	—
Completed	Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depressio NCT03730064	Martin Lan	EARLY_Phase 1
Completed	Brain Stimulation and Cognitive Training NCT03338673	University of Michigan	N/A
Withdrawn	Effects of Cannabis Abstinence on Symptomology and Cognition in Bipolar Disorder NCT03629106	Centre for Addiction and Mental Health	N/A
Completed	Evaluating the Effectiveness of Imagery Focussed Therapy NCT03750305	Maastricht University	N/A
Completed	Efficacy of Convulsive Therapies for Bipolar Depression NCT03641300	Centre for Addiction and Mental Health	N/A
Completed	Integrated Care (IC) Models for Patient-Centered Outcomes NCT03451630	University of Pittsburgh	N/A
Unknown	An Eye Tracking Study of Affective Disorder Patients With Suicide Risk NCT03711045	Central South University	—
Unknown	Imaging 5HT7 Antagonist Effects in Bipolar Disorder NCT03633357	King's College London	N/A
Unknown	Continuous Theta Burst Stimulation as an add-on Treatment for Bipolar Depression NCT03603561	Universiteit Antwerpen	N/A
Unknown	Management of my Bipolarity Intervention in Bipolar Disorder Patients NCT04643210	Cyprus University of Technology	N/A
Completed	Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness NCT03208036	VA Office of Research and Development	N/A
Terminated	Toward Exercise as Medicine for Adolescents With Bipolar Disorder NCT03562520	Sunnybrook Health Sciences Centre	N/A
Completed	Ion Channel Genetic Biomarkers: Diagnostic Capabilities in the Assessment of Bipolar Disorder NCT03572426	University of Colorado, Denver	—

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