NCT04127604

Post-Hospital Intervention for Veterans With Comorbid Bipolar and Substance Use Disorders

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 138 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This trial aims to evaluate the effectiveness of a novel intervention for Veterans with co-occurring bipolar and substance use disorders following a psychiatric hospitalization. Half of the participants will receive a specialized psychosocial intervention program, while the other half will receive an enhanced safety monitoring program, both provided in addition to their routine care.

Detailed description

This randomized controlled trial will evaluate the effectiveness of a psychosocial intervention designed to improve treatment adherence in Veterans with comorbid bipolar disorder and substance use disorders (BP-SUD) following a psychiatric hospitalization. Participants will be randomized to either the specialized psychosocial intervention or an enhanced safety monitoring program, both as adjuncts to VA treatment as usual. Veterans with BP-SUD will be recruited from the Providence VAMC inpatient psychiatric unit and assessed at baseline and at 3 (mid-treatment), 6 (post-treatment), and 9-month post-discharge.

Conditions

• Bipolar Disorder
• Substance Use Disorders

Interventions

Type	Name	Description
BEHAVIORAL	Integrated Treatment Adherence Program for Veterans (ITAP-VA)	Psychosocial support and treatment to improve treatment adherence, symptoms, and functioning.
BEHAVIORAL	Safety Assessment and Follow-up Evaluation (SAFE)	Measurement-based care assessment and evaluation.

Timeline

• Start date: 2020-11-02
• Primary completion: 2025-09-30
• Completion: 2025-09-30
• First posted: 2019-10-15
• Last updated: 2025-10-22

Locations

1 site across 1 country: United States