Trials / Conditions / Substance Use Disorders

Substance Use Disorders

411 registered clinical trials studyying Substance Use Disorders — 83 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Yuva Sath: A Peer-led Behavioral Intervention to Support Substance Use Treatment and HIV Prevention Among Youn NCT06510192	Massachusetts General Hospital	N/A
Suspended	Co-Active Therapeutic Theatre (Co-ATT) for Dual-Diagnosis Patients NCT06187701	Boston Medical Center	N/A
Not Yet Recruiting	Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder NCT07499583	Indiana University	Phase 1 / Phase 2
Not Yet Recruiting	Recovery Inspired Support Engagement (RISE) Pilot NCT07519759	Mclean Hospital	N/A
Recruiting	Peer-Delivered Behavioral Activation in a CCBHC NCT07219394	Wayne State University	N/A
Not Yet Recruiting	Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use NCT07218549	Christopher D. Verrico	Phase 1
Not Yet Recruiting	Enhancing Addiction Treatment Through Psychoeducation NCT07178158	Virginia Commonwealth University	N/A
Not Yet Recruiting	Innovating Technology Solutions for Residents in Support Housing Communities w SUD Through Community-Engaged R NCT07001020	Oregon Research Behavioral Intervention Strategies, Inc.	N/A
Not Yet Recruiting	Impact of Federal and State Medications for Opioid Use Disorder (MOUD) Policy Changes During the Pandemic NCT07232641	Boston University	—
Recruiting	Neuroimaging of Adolescent Cannabis Use Treatment NCT07340554	Indiana University	N/A
Recruiting	Prevent Language Delays and Disorders Among Children of Caregivers With Substance Use Disorders With Community NCT07529327	University of Oregon	N/A
Not Yet Recruiting	Efficacy of Digital Problem Solving Application in Reduction of Anxiety, Depression and Substance Use Disorder NCT06346431	7 Generation Games	EARLY_Phase 1
Not Yet Recruiting	Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking NCT07328594	Legacy Health System	Phase 4
Not Yet Recruiting	Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation NCT07387796	The University of Texas at Dallas	N/A
Recruiting	Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth NCT07364799	SoundHeal	N/A
Recruiting	HIV, Equity, and Addiction Training (HEAT) Program NCT06370481	University of Alabama at Birmingham	N/A
Recruiting	tAN for Substance Use Disorder NCT07281261	Spark Biomedical, Inc.	N/A
Recruiting	Temporal Interference Methods for Addiction Treatment NCT07210268	Indiana University	N/A
Recruiting	Efficacy of an EMDR App for PTSD and SUD NCT07146633	Centre for Addiction and Mental Health	N/A
Recruiting	Improving Outcomes in Social Services Through Routine Outcome Monitoring and Systematic Client Feedback NCT07303608	Karolinska Institutet	N/A
Withdrawn	The Longitudinal Impact of SES and the CNDS on Recovery From SUD NCT05103514	Virginia Polytechnic Institute and State University	—
Recruiting	A Randomized Controlled Trial of Digital CBT to Treat Addiction: Digital RITch®CBT vs. Standard CBT NCT05943171	University of Rochester	N/A
Recruiting	Shared Decision Making to Treat Or Prevent (STOP) HIV in Justice Populations (R33) NCT07223398	Yale University	N/A
Not Yet Recruiting	Safe & Sound Protocol in Adults With Trauma and SUD NCT07219056	Caron Treatment Centers	N/A
Recruiting	Adaptation of the ECCCLORE Program for Patients With Addictive and Traumatic Problems NCT07193914	Centre Hospitalier Universitaire de Nīmes	N/A
Recruiting	Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation NCT06103370	Johns Hopkins University	N/A
Recruiting	STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking NCT06922617	Medical University of South Carolina	N/A
Enrolling By Invitation	Senyo Health With Substance Use Disorder (SUD) in Primary Care NCT06743282	Mayo Clinic	N/A
Withdrawn	Individualized Neuromodulation of Craving Control for Meth Use Disorders NCT06695637	University of Minnesota	EARLY_Phase 1
Not Yet Recruiting	Khanya Ekhaya: A Home-Based Intervention NCT06985641	University of Maryland, College Park	N/A
Not Yet Recruiting	Adaptation of Written Exposure Therapy in Substance Treatment NCT07108608	Potomac Health Foundations	N/A
Recruiting	Family Support Protocol for Adolescent Internalizing Disorders NCT06413979	The National Center on Addiction and Substance Abuse at Columbia University	N/A
Recruiting	Supervision in Substance Use Disorder Treatment Programs NCT07262372	University of Arkansas	N/A
Recruiting	Evaluating a One-Year Version of the Parent-Child Assistance Program NCT06163651	University of Oklahoma	N/A
Recruiting	Families Left Behind NCT06854757	RAND	N/A
Recruiting	Improving Social Functioning in People With Substance Use and Mental Health Disorders Using VR NCT06677515	Sykehuset Innlandet HF	N/A
Recruiting	DEVELOPMENT OF A NOVEL PEER RECOVERY SUPPORTER TRAINING PLATFORM NCT07044531	Thrive Digital Health, LLC	N/A
Recruiting	COPEWeb Training for Providers NCT05812131	VA Office of Research and Development	N/A
Completed	Quantitative Xylazine Measurement in ED NCT06949605	Icahn School of Medicine at Mount Sinai	—
Withdrawn	Substance Use Disorder, Brain and Behavioral Regulation NCT05910749	University of Puerto Rico	N/A
Recruiting	A Novel Blood Test as a Biomarker in Mental Health NCT06856161	Fraser Health	—
Recruiting	Mitigating the Impact of Stigma and Shame Among People Living With HIV and Substance Use Disorders NCT05934305	Boston University	N/A
Recruiting	tDCS Plus Varenicline for Smoking Cessation NCT06798324	Centre for Addiction and Mental Health	Phase 4
Active Not Recruiting	Achieving Equity in Patient Outcome Reporting for Timely Assessments of Life With HIV and Substance Use NCT06682468	University of Chicago	N/A
Recruiting	Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People NCT05816083	Medical University of South Carolina	N/A
Completed	Parenting Intervention for Mothers With Substance Use Disorder NCT06489522	Boston Medical Center	N/A
Recruiting	The Collaborative Care PrTNER Study NCT06585631	Children's Hospital of Philadelphia	N/A
Not Yet Recruiting	An Intervention to Improve HIV Pre-exposure Prophylaxis Initiation, Adherence and Linkage to Care for Recently NCT06316089	Rhode Island Hospital	N/A
Recruiting	Prevention of Mental Disorders Through Self-efficacy Interventions NCT06738953	Health and Medical University Potsdam	N/A
Completed	STOP (Shared Decision Making to Treat Or Prevent) HIV in Justice Populations NCT06439329	Yale University	N/A
Not Yet Recruiting	Effect of Social Isolation on the Role of Pavlovian Mechanisms for Control Over Alcohol Use NCT06256952	Charite University, Berlin, Germany	N/A
Recruiting	Modification of Inhibitory Control and Craving Through Transcranial Direct Current Stimulation (tDCS) as an Ad NCT06959342	Central Institute of Mental Health, Mannheim	N/A
Active Not Recruiting	The STop UNhealthy Substance Use Now Trial NCT06524232	Ohio State University	N/A
Recruiting	Ketamine for Methamphetamine Use Disorder NCT06496750	University of Texas Southwestern Medical Center	Phase 2
Recruiting	Massed Prolonged Exposure for PTSD in Substance Use Treatment NCT06296186	Veterans Medical Research Foundation	N/A
Recruiting	Substance Use Prevention for Youth With Parents in Recovery NCT05397691	Brown University	N/A
Completed	Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches NCT05847621	Emory University	N/A
Recruiting	Role of Pavlovian Mechanisms for Control Over Substance Use NCT06701487	Technische Universität Dresden	—
Not Yet Recruiting	Effectiveness of Indo-SURFT in Reducing Addictive Substance Use in Women With Substance Use Disorders NCT06174714	Indonesia University	N/A
Terminated	Anchoring Sequential Intermittent Long Acting Antimicrobials With Medication for Opioid Use Disorder (MOUD) fo NCT05521880	University of Maryland, Baltimore	Phase 4
Recruiting	Emergency Medicine Peer Outreach Worker Engagement for Recovery NCT06320015	University of California, Los Angeles	—
Active Not Recruiting	Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk NCT05828849	NYU Langone Health	N/A
Completed	Brief Contextual-Behavioral vs Twelve-Step Intervention for Emotion Regulation in Substance Use: Pilot Study NCT07337733	Lauro Gutiérrez Castro	N/A
Recruiting	Trauma Screening/Referral and Interpersonal Violence Prevention for Women with Substance Use Disorders NCT06608979	Clemson University	N/A
Not Yet Recruiting	Collaborative Open Research Initiative Study (CORIS-1) NCT06357650	Chisquares Incorporated	—
Completed	Has CBT an Effect on Emotional Intelligence in Patients With Substance Use Disorder? NCT06310668	Egyptian Medical Syndicate	N/A
Completed	Sociodemographic and Clinical Characteristics of Patients Admitted to the Addiction Management Unit NCT05777200	Assiut University	—
Completed	The Effects of Mass Media Photographs on Drug-Related Stigma NCT06743178	Johns Hopkins Bloomberg School of Public Health	N/A
Completed	Validation of the Behavioral Activation for Depression Scale in Individuals With Substance Use Disorders NCT07395700	Lauro Gutiérrez Castro	—
Completed	Intervention for Managing Physical Reactions to Overwhelming Emotions NCT06299657	Ohio State University	N/A
Recruiting	Assessing Habitual, Goal-Directed, and Pavlovian Influences in Alcohol Use Disorder NCT06701500	Technische Universität Dresden	—
Unknown	AI to Support Mental Health Case Management Providers NCT06280170	Eleos Health	N/A
Completed	A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants NCT06316973	Clear Scientific, Inc.	Phase 1
Completed	Life-Skills Training Program: Its Effect on Self-efficacy Among Patients With Substance Use Disorders NCT07174960	Ain Shams University	N/A
Active Not Recruiting	Reducing Readmissions: BNI Trial in Substance Use Disorder NCT06223191	Universidad Nacional Autonoma de Honduras	N/A
Active Not Recruiting	Integrated Care and Treatment for Severe Infectious Diseases and Substance Use Disorders Among Hospitalized Pa NCT05688423	Columbia University	N/A
Completed	The Pocket Skills Adjunct Project NCT06402240	University of Windsor	N/A
Withdrawn	TAU vs m-SBIRT in Primary Care NCT06250153	Medical University of South Carolina	N/A
Recruiting	Utilizing Battlefield Acupuncture to Treat Chronic Pain NCT06128772	Edith Nourse Rogers Memorial Veterans Hospital	N/A
Enrolling By Invitation	Clinic-level Implementation of mHealth to Improve HIV Viral Suppression for Patients With Substance Use Disord NCT06109571	University of Wisconsin, Madison	N/A
Recruiting	Preconception Intervention for Incarcerated Women With Substance Use NCT05854836	St. Louis University	N/A
Unknown	Transcranial Magnetic Stimulation in Substance Use Disorder Patients NCT06066164	Assiut University	N/A
Unknown	Addiction-focused EMDR in Inpatients Who Use Non-opioid Drugs: a Multiple Baseline Study NCT05923697	IrisZorg	N/A
Completed	Multi-Level Stigma Intervention for Mental Health Services NCT06200012	Wayne State University	N/A
Withdrawn	Augmentation of Standard Psychotherapy With a Habit Change App NCT06110728	Rebecca Tavernier	N/A
Active Not Recruiting	Community Intervention to Eliminate HCV Among People Who Use Drugs. NCT05794646	ANRS, Emerging Infectious Diseases	N/A
Completed	Parenting Young Children in Pediatrics NCT06273228	University of Oregon	N/A
Completed	Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion NCT05976646	Virginia Commonwealth University	Phase 1 / Phase 2
Unknown	The Effectiveness of A-CRA in Compulsory Institutional Care for Youth NCT06094972	Karolinska Institutet	N/A
Completed	Program for Alleviating and Reducing Trauma, Stress, and Substance Use NCT06207409	Cambridge Health Alliance	N/A
Completed	Feasibility of Brief Behavioral Therapy for Insomnia (BBTI) in SUD Recovery NCT05935735	Johns Hopkins University	N/A
Recruiting	EMA for Predicting Treatment Outcomes in Patients With SUD NCT06470698	University of Huelva	—
Recruiting	Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders NCT06434818	Evon Medics LLC	Phase 2
Completed	Effect of Mindfulness-Based Relapse Prevention Program on Readiness for Change and Self-efficacy Among Clients NCT05990699	Alexandria University	N/A
Completed	Kentucky Access to Recovery Evaluation NCT05889702	Terry Bunn	—
Active Not Recruiting	Enhancing Substance Use Treatment Services to Decrease Dropout and Improve Outpatient Treatment Utilization in NCT05374395	UConn Health	N/A
Completed	Evaluating Supplementing Residential Substance Use Treatment With Written Exposure Therapy for Veterans With P NCT05536908	VA Office of Research and Development	N/A
Recruiting	Prevalence of Psychiatric and Substance Abuse Disorders Among People in Precarious Situations in Cayenne NCT06065553	Centre Hospitalier de Cayenne	—
Completed	Emotional Regulation in People With Co-occurring Posttraumatic Stress Disorder and Substance Use Disorder NCT05531318	King's College London	—
Unknown	tDCS and Impulsivity NCT05845164	University of Arizona	N/A
Active Not Recruiting	Supporting Treatment Access and Recovery Through Linkage and Support NCT05713695	University of Massachusetts, Worcester	N/A
Completed	Digital Mindfulness-Based Treatment for Substance Use Disorder Recovery NCT05852015	Yale University	N/A
Unknown	Peer to Community (P2C) Model: A Pilot Randomized Controlled Trial NCT05884749	Western University, Canada	N/A
Terminated	ASK-PrEP (Assistance Services Knowledge-PrEP) NCT05934877	Friends Research Institute, Inc.	N/A
Recruiting	Integrative Couple Treatment for Gambling/Substance Use Disorder NCT05833503	Université du Québec à Trois-Rivières	N/A
Completed	Enhancing Prospective Thinking in Early Recovery (PARK) NCT05908097	Indiana University	EARLY_Phase 1
Active Not Recruiting	Improving Maternal Mental Health & SUD Screening and Treatment NCT05764213	Medical University of South Carolina	N/A
Recruiting	Testing Strategies to Improve Substance Misuse Prevention Research Use in State Policy Contexts NCT06856148	Penn State University	N/A
Recruiting	Enhancing Prospective Thinking in Early Recovery NCT05835921	Indiana University	N/A
Unknown	Evaluating the Effectiveness of Mobile Self-guided Psychological Interventions to Reduce Relapse in Substance NCT05730504	PredictWatch	N/A
Active Not Recruiting	Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder NCT05322954	University of Wisconsin, Madison	Phase 1
Recruiting	IMPOWR-ME Project 1: Trial of Yoga and Physical Therapy Onsite at Opioid Treatment Programs NCT05492825	Albert Einstein College of Medicine	N/A
Completed	Planning a Multi-Level Intervention to Reduce Substance Use Stigma in HIV Prevention and Care NCT05925374	Wayne State University	N/A
Recruiting	CARS: Cannabis and Alcohol Reduction Study NCT05486234	Medical University of South Carolina	N/A
Completed	Diagnostic Survey of Mental and Substance Use Disorders Among Norwegian College and University Students NCT05731102	Norwegian Institute of Public Health	—
Enrolling By Invitation	Comparing the Effect of Adding a Remote Self-reporting Tool for Distress and Fit-for-purpose Mental Health & A NCT05626374	Royal Victoria Hospital, Canada	N/A
Completed	Multiple Ascending Dose Study of TMP-301 in Healthy Subjects NCT06025396	Tempero Bio, Inc.	Phase 1
Completed	Heart Rate Variability Biofeedback for Substance Use Disorder: A Randomized Clinical Trial NCT05454657	Massachusetts General Hospital	N/A
Completed	Smartphone Intervention for Overdose and COVID-19 NCT05518461	University of Wisconsin, Madison	N/A
Recruiting	Home Treatment for Individuals Suffering From Severe Addictive Disorders NCT05563363	Louise Penzenstadler	N/A
Completed	Written Exposure in Substance Treatment NCT06296940	Potomac Health Foundations	N/A
Completed	Investigation of the Effect of Cognitive Behavioral Approach-Based Psychoeducation NCT05941195	Aydin Adnan Menderes University	N/A
Recruiting	Smoking Cessation and Menstrual Cycle Phase NCT05515354	Centre for Addiction and Mental Health	Phase 4
Completed	Criminal Justice Coordinated Transitional Care NCT05376371	University of Wisconsin, Madison	N/A
Unknown	Correlation of Genetic Variations With Clinical Response in Substance Use Disorder NCT05833399	Alexandria University	—
Completed	F-CaST for Individuals With Substance Use Disorder NCT05647863	Tel Aviv University	N/A
Recruiting	The Oklahoma Parent-Child Assistance Program NCT05534568	University of Oklahoma	N/A
Completed	The Anchor Study: Digitally Delivered Intervention for Reducing Problematic Substance Use NCT04925570	Woebot Health	Phase 2
Active Not Recruiting	Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD) NCT04768920	University of Michigan	N/A
Active Not Recruiting	Socializing a Science-Based Digital Therapeutic for Substance Use Disorders NCT05648786	Square2 Systems, Inc.	N/A
Enrolling By Invitation	Indigenous Recovery Planning for American Indians NCT05612061	Montana State University	N/A
Active Not Recruiting	Harnessing Telemedicine to Improve Alcohol Use Disorder Outcomes in Primary Care Patients NCT05410561	University of Michigan	N/A
Active Not Recruiting	Evaluation of RRFT for Co-occurring SUD and PTSD Among Teens NCT05384223	Medical University of South Carolina	N/A
Recruiting	Implementation of a Patient-centered, Reproductive Planning Decision Support Tool (MyPath) Among Women With Su NCT04939012	University of Pittsburgh	N/A
Completed	Multifamily Group Psychoeducation for SUD's in Turkey NCT05564559	Ege University	N/A
Unknown	Contingency Management for Recovery Oriented Activities at Recovery Houses NCT05585203	Wayne State University	N/A
Completed	Substance Use and Loneliness NCT05338268	VA Office of Research and Development	N/A
Terminated	Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization NCT05118204	Montefiore Medical Center	Phase 4
Recruiting	Written Exposure Therapy for Veterans With SUD and PTSD NCT05327504	VA Office of Research and Development	N/A
Completed	Using Aromatherapy in Substance Use Disorder NCT05660434	West Virginia University	N/A
Completed	Feasibility of Music Therapy in Community Substance Misuse Treatment Services NCT05180617	Anglia Ruskin University	N/A
Completed	Implementing a Pharmacist-Integrated Collaborative Model of Medication Treatment for Opioid Use Disorder NCT05310786	Trustees of Dartmouth College	N/A
Withdrawn	Trauma-Focused Intervention With Women Experiencing Homelessness NCT05873517	Rush University Medical Center	Phase 1
Completed	Real-world Momentary Assessment of Kratom Use Accompanied by Product Assays: A Natural-history Study for Inter NCT05457803	National Institute on Drug Abuse (NIDA)	—
Completed	Linkage to Care for Persons with Hep C Infection NCT05397067	Carilion Clinic	N/A
Withdrawn	Preventing Youth Substance Use With Family Talk NCT04400227	Boston Medical Center	N/A
Completed	The Substance Use and Health Risk Intervention (SUHRI) for Justice-involved Youth NCT06132282	Texas Christian University	N/A
Terminated	Distress Tolerance for Benzodiazepine Discontinuation NCT05250570	University of Pittsburgh	N/A
Unknown	the Role of Repetitive Trans Cranial-magnetic Stimulation in Craving Reduction Among Opioid Use Disorder Patie NCT04691167	Ain Shams University	N/A
Active Not Recruiting	Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use Disorders NCT05348317	VA Office of Research and Development	N/A
Completed	Community Reinforcement and Family Training for Early Psychosis (CRAFT-EP) and Substance Use: A Pilot Study NCT05380583	Mclean Hospital	N/A
Completed	Expanding Reach of Evidence-based Psychotherapy for Veterans With Co-occurring Anxiety and Substance Use Disor NCT05372185	Baylor College of Medicine	N/A
Active Not Recruiting	Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care NCT04601064	Johns Hopkins University	N/A
Unknown	Piloting a Patient-Reported Outcome Measure for Opioid Use Disorder Recovery in a Clinical Setting NCT05388045	Brandeis University	N/A
Completed	Substance Use and Eating Disorders : Food Craving and Addiction Transfer NCT05315635	Centre Hospitalier Charles Perrens, Bordeaux	—
Completed	Strategies to Enhance Recruitment and Retention of Black Individuals Into Clinical Trials for Substance Use Di NCT05124119	University of Texas Southwestern Medical Center	—
Completed	Open Trial to Improve Retention in Care for Persons With HIV Who Use Substances NCT05101044	Brown University	N/A
Unknown	VR as a Facilitator for Participation in Society Among Persons With MHD/SUD NCT05653167	Sykehuset Innlandet HF	—
Completed	RAE (Realize, Analyze, Engage) NCT05227339	ContinueYou, LLC	Phase 2 / Phase 3
Completed	Feasibility, Acceptability and Preliminary Treatment Effects of A-CRA for Youth in Compulsory Institutional Ca NCT05081934	Karolinska Institutet	N/A
Completed	Community Reinforcement Approach and Family Training for Substance Use in Early Psychosis Intervention NCT05300633	Centre for Addiction and Mental Health	N/A
Completed	Adaptation of Community Reinforcement Approach for the Treatment of Drug Addiction NCT06559631	Muhammad Saghir	N/A
Completed	Eye Movement Desensitization and Reprocessing as a Treatment for Substance Use Disorders NCT05488691	Hospital Clinic of Barcelona	N/A
Completed	PrEP at a Syringe Services Program NCT04782180	University of Miami	Phase 4
Recruiting	Minds and Mentors Program- R33 NCT05363371	University of Alabama, Tuscaloosa	N/A
Not Yet Recruiting	Neurobiological Effects of Transcranial Direct Current Stimulation Treatment in Alcohol Use Disorder NCT04897295	ITAB - Institute for Advanced Biomedical Technologies	N/A
Unknown	cl[Nical Study of Succide Among Patient With Psychoactive Substance Use Disorders NCT05107180	Assiut University	—
Completed	Nursing Attitudes Towards SUD NCT05218681	University of Pennsylvania	N/A
Completed	A Dialectical Behavioral Therapy Digital Health Solution for Outpatients Seeking Support for Substance Use NCT05094440	Centre for Addiction and Mental Health	N/A
Completed	Pilot: Digital Therapeutic vs Education for the Management of Problematic Substance Use NCT04974645	Woebot Health	N/A
Completed	Online Cognitive Behavioural Therapy for Substance Use Disorder: The Impact of Peer Support NCT05127733	Centre for Addiction and Mental Health	N/A
Active Not Recruiting	EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy NCT04921787	Gavin Bart	N/A
Unknown	Illness Management and Recovery- a Cluster Randomized Controlled Trial Within a Forensic Mental Inpatient Sett NCT04695132	Karolinska Institutet	N/A
Completed	Intervention to Improve HIV Self-care Among People Who Inject Drugs NCT05819411	Massachusetts General Hospital	N/A
Completed	Eliminating HCV in Rural South Carolina Utilizing NP Led Mobile Clinics and Virtual Care Coordination NCT05369507	Prisma Health-Upstate	N/A
Completed	Feasibility and Acceptability of a Substance Use Screening and Brief Intervention for Youth Living With HIV in NCT04998045	Moi University	N/A
Unknown	Clinical Characteristics of Patients Referred to a Substance Abuse Liaison Department in an Academic Hospital, NCT04916028	Centre Hospitalier Universitaire, Amiens	—
Completed	Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During t NCT04916275	Centre Hospitalier Universitaire de Nīmes	—
Completed	Trauma and Trauma-Focused Therapy in the University of Kentucky SMART Clinic NCT04760418	Christal L Badour	N/A
Completed	Virtual Mantram Program for Patients With PTSD and SUD NCT05058963	Centre for Addiction and Mental Health	N/A
Recruiting	Presence of PTSD and Emotion Dysregulation Among Inpatients With Substance Use Disorder NCT06345053	Norwegian University of Science and Technology	N/A
Terminated	Substance Use Disorder (SUD)-Associated Infections' Treatment With Dalbavancin ENabling OUtpatient Transition NCT04847921	University of Colorado, Denver	Phase 2 / Phase 3
Recruiting	Young Houston Emergency Opioid Engagement System NCT04811014	The University of Texas Health Science Center, Houston	Phase 4
Completed	A Psychoeducational Intervention for Brain Awareness, Metacognition, Self-efficacy and Treatment Motivation NCT05812469	Istanbul University - Cerrahpasa	N/A
Active Not Recruiting	The Norwegian Addiction, Pain and Trauma Study NCT04908410	University Hospital, Akershus	—
Withdrawn	HIV + Service Delivery and Telemedicine Through Effective PROs NCT04489667	University of Alabama at Birmingham	N/A
Completed	Benzodiazepine Discontinuation in Opioid Agonist Therapy NCT04109118	Boston Medical Center	Phase 2
Unknown	Single and Dual Task Balance Exercises in Substance Use Disorders NCT05944536	Ankara Yildirim Beyazıt University	N/A
Completed	Continuing Care App for Probationers and Parolees NCT04574193	COG Analytics	N/A
Completed	SMART Trial: Intrapersonal and Interpersonal Stigma Reduction NCT04693416	University of Tennessee	Phase 2
Completed	Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Car NCT05907174	University of Maryland, College Park	N/A
Completed	Connect2BWell: An Evidence-Based Screening, Brief Intervention, and Referral to Treatment (SBIRT) Program NCT04745065	Pro-Change Behavior Systems	N/A
Terminated	Treating Adolescents With CBT and OBH NCT04760938	University of New Hampshire	N/A
Active Not Recruiting	Factors Predicting Outcome in Group Treatment of Alcohol Use Disorders (AUDs) NCT04822987	The Hospital of Vestfold	—
Completed	Delivering Contingency Management in Outpatient Addiction Treatment NCT04544124	University of Calgary	N/A
Unknown	Preventing OUD in Justice-Involved Youth NCT04901312	Seattle Children's Hospital	N/A
Completed	Promoting Caregiver-child Attachment and Recovery Through Early Intervention (pCARE): A Pilot Randomized Contr NCT04675099	Baystate Medical Center	N/A
Recruiting	Substance Use Treatment and Access to Resources (STARS) Project NCT04459000	University of Oklahoma	N/A
Completed	Psychotherapy for PTSD Among Veterans Also Receiving Drug or Alcohol Treatment NCT04581434	Center for Veterans Research and Education	N/A
Completed	Repetitive Transcranial Magnetic Stimulation in Drugs Addiction NCT06244329	The Hong Kong Polytechnic University	N/A
Recruiting	Problematic Use of the Internet in Child and Adolescent Psychiatry NCT04723498	Susanne Walitza	N/A
Recruiting	Cue Effects in Human Addiction: Pavlovian to Instrumental Transfer NCT05992272	Charite University, Berlin, Germany	—
Terminated	Evaluating MyPath to Enhance Reproductive Autonomy and Liberate Decision-making NCT04627805	University of Pittsburgh	N/A
Completed	Strategies to Reduce Addiction Stigma Among Health Professionals NCT05127707	Johns Hopkins Bloomberg School of Public Health	N/A
Completed	Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders NCT04556552	Emory University	Phase 3
Completed	Post-Hospital Intervention for Veterans With Comorbid Bipolar and Substance Use Disorders NCT04127604	VA Office of Research and Development	N/A
Completed	Smartphone Addiction Recovery Coach for Young Adults (SARC-YA) Experiment NCT03301012	Chestnut Health Systems	N/A
Completed	Couples ART Adherence Intervention for PWID in Kazakhstan NCT03555396	Columbia University	N/A
Completed	Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States NCT04163341	Michael J Mugavero, MD	N/A
Completed	Intervention for Comorbid Substance Use and Bipolar Disorders NCT04202393	Butler Hospital	N/A
Completed	PrEP Readiness Interventions for Supporting Motivation NCT04205487	Florida International University	N/A
Completed	Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase NCT04248933	University of Maryland, College Park	N/A
Completed	A Mobile App for Peer-led Seeking Safety NCT03846115	Treatment Innovations	N/A
Completed	Automated Assessment Using Facial Coding NCT03551886	Treatment Innovations	N/A
Completed	Families With Substance Use and Psychosis: A Pilot Study NCT04284813	Mclean Hospital	N/A
Withdrawn	Prevention of Benzodiazepine Misuse in Primary Care NCT04533230	Karolinska Institutet	N/A
Unknown	Sleep Treatment for Addiction Recovery NCT04198311	University of Missouri-Columbia	N/A
Active Not Recruiting	The Human Stress Response in a Simulated ED Setting NCT04317482	University of Arkansas	N/A
Completed	User Acceptability of a Device-Based Opioid Overdose Intervention NCT04530591	University of Pennsylvania	—
Withdrawn	M-Health for Teen Substance Abuse and Mental Illness Pilot NCT04281719	Indiana University	N/A
Unknown	IT to Support Integration of Social Determinant of Health Services to Reduce Avoidable Emergency Department Vi NCT04125433	Northern New York Rural Behavioral Health Institute	N/A
Terminated	Temporal Interference Neurostimulation and Addiction NCT04432064	Indiana University	N/A
Completed	Coaching Performance Driven Practice Change in the Context of Value Based Purchasing Under New York Medicaid NCT04632238	NYU Langone Health	N/A
Unknown	Clozapine Versus Olanzapine as Treatment for Comorbid Psychotic Disorder and Substance Use Disorder NCT03857581	Augusta University	Phase 4
Completed	W-SUDs for COVID-19 NCT04460027	Woebot Health	Phase 1
Unknown	The Follow-up Study for the Patients of Illicit Substance Use Disorder NCT04426565	Kaohsiung Kai-Suan Psychiatric Hospital	N/A
Unknown	A Digital Smoking Cessation Intervention for Adults With Substance Use Disorder NCT04419922	BrightView LLC	—
Completed	Neurobiological Mechanisms of Chess as an Add-On Treatment Against SUD NCT04057534	Central Institute of Mental Health, Mannheim	N/A
Completed	Woebot for Substance Use Disorders NCT04096001	Woebot Health	Phase 1
Unknown	Evaluating the Chain of Addiction Care (CAC) NCT05401136	Radboud University Medical Center	—
Active Not Recruiting	From Addiction to Employment. NCT04289415	Oslo University Hospital	N/A
Completed	Integrated Intervention Post-Sexual Assault NCT04724746	Medical University of South Carolina	N/A
Recruiting	Cognitive Remediation in Forensic Mental Health Care NCT04610697	The Royal Ottawa Mental Health Centre	N/A
Completed	Exercise Training as Medicine for Substance Use Disorder Patients NCT04065334	St. Olavs Hospital	N/A
Completed	Minds and Mentors Program (MiMP)- R61 NCT04233671	University of Alabama, Tuscaloosa	N/A
Enrolling By Invitation	MIO-CPP to Improve the Well-being, Permanency, and Safety Outcomes for Young Children at Risk of or in Out-of- NCT04294134	Children's Hospital of Philadelphia	N/A
Unknown	The Canadian Underage Substance Use Prevention Trial NCT04198974	St. Justine's Hospital	N/A
Recruiting	Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disord NCT04197921	InSightec	N/A
Completed	Mobile Enhanced Prevention Support for People Leaving Jail NCT04036396	University of California, Los Angeles	N/A
Terminated	Routine Pregnancy Screening for Women on Opioid Substitution Therapy NCT03489174	McMaster University	N/A
Completed	Guanfacine to Improve Substance Use Outcomes in Women NCT03980184	Yale University	Phase 2
Withdrawn	Investigating the Efficacy of Caloric Vestibular Stimulation in the Treatment of Substance Use Disorders NCT03652311	Wake Forest University Health Sciences	N/A
Completed	Pragmatic RCT of SBIRT-PM NCT04062214	Yale University	N/A
Completed	A Virtual Navigation Intervention to Reduce Behavioral Health Admissions From Rural Emergency Departments NCT04148521	Wake Forest University Health Sciences	N/A
Completed	Addiction Treatment Outcome Monitoring Study NCT04155385	University of Washington	N/A
Completed	Adapting Personality-Targeted Interventions for Reducing Substance Misuse and Related Outcomes in Youth in You NCT04162977	St. Justine's Hospital	N/A
Completed	Opportunstic Hepatitis C Virus Treatment NCT04220645	University Hospital, Akershus	N/A
Completed	Technologically-Augmented Referrals to Mitigate Addiction Consequences NCT04401215	Washington State University	N/A
Completed	Zepatier in Patients with Substance Use NCT04048850	University of Illinois at Chicago	—
Completed	Barriers to Substance Use Disorder Recovery NCT04098614	Prisma Health-Upstate	N/A
Completed	E-health Implementation (Iowa) NCT03954184	University of Wisconsin, Madison	N/A
Completed	Leveraging Implementation Science to Increase Access to Trauma Treatment for Incarcerated Drug Users NCT04007666	University of Arkansas	N/A
Unknown	MBRP on Reducing Craving and Addictive Behaviour in Adults NCT04034732	Chinese University of Hong Kong	N/A
Unknown	Peer MI in FQHCs for Substance-using Emerging Adults NCT03758131	University of Illinois at Urbana-Champaign	Phase 2
Completed	The Effect of Self-Forgiveness on Self-Stigma in Addiction. NCT03971097	University of Pittsburgh	N/A
Completed	MOms in REcovery (MORE) Study: Defining Optimal Care NCT04251208	Trustees of Dartmouth College	—
Withdrawn	Mindfulness-based Therapeutic Sailing (MBTS) Versus Standard Recreation Therapy Activity (SRT) NCT04639596	VA Salt Lake City Health Care System	N/A
Withdrawn	Patient-Centered Care for Opioid Use Disorders in Federally Qualified Healthcare Centers and Specialty Care Se NCT03367234	Public Health Management Corporation	N/A
Terminated	Zambia Common Elements Treatment Approach Pilot Study NCT03966885	Columbia University	N/A
Completed	Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps) NCT03512418	Brigham and Women's Hospital	Phase 3
Completed	NCARE, Transition to Recovery NCT03737864	University of Colorado, Denver	N/A
Completed	HIV+ Substance Users Released From Jail NCT03834779	University of Texas Southwestern Medical Center	N/A
Completed	Project Matter: Intervention to Improve HIV Self-care Among Men Who Have Sex With Men (MSM) With Substance Use NCT03899220	Massachusetts General Hospital	N/A
Suspended	Effects of In-Home Addiction Treatment for First Responders NCT03907709	In-Home Addiction Treatment Institute, Inc.	—
Completed	Measurement Training and Feedback System: Family-Based Services NCT03342872	The National Center on Addiction and Substance Abuse at Columbia University	N/A
Completed	ART-CHESS: A Mobile Health Application to Support People Living With HIV and Addiction NCT03873129	University of Wisconsin, Madison	N/A
Completed	Providing Expanded Continuous Labor Support to Pregnant Women in New Mexico With Substance Use Disorders NCT03808909	University of New Mexico	N/A
Completed	Contingency Management Using Smartphone App in Patients With SUD NCT04162132	BrightView LLC	—
Completed	Pilot of Pragmatic SBIRT Study NCT03307967	Yale University	N/A
Enrolling By Invitation	Healthy People Initiative (HPI) NCT03506867	Ottawa Hospital Research Institute	N/A
Completed	A Therapeutic Workplace to Address Poverty and Substance Use NCT03519009	Johns Hopkins University	N/A
Completed	Personality Disorders and Substance Use Disorders in a Sexual Context in the Man Having Sex With Other Men Pop NCT03753737	Hospices Civils de Lyon	—
Withdrawn	Can The Bridge Transition Opiate Use Disorder Patients in Stable Recovery From Buprenorphine to Naltrexone NCT03762798	The Cleveland Clinic	N/A
Completed	Project PRIDE (Promoting Resilience In Discriminatory Environments) NCT03528135	University of Houston	N/A
Completed	Diagnostic Survey of Mental and Substance Use Disorders in HUNT (PsykHUNT) NCT04661228	Norwegian Institute of Public Health	—
Completed	Evaluating The Efficacy Of A Mind-Body Intervention In Overcoming Opioid Addiction NCT03791645	Ohio State University	N/A
Completed	CBT4CBT for Women in Residential Treatment for Substance Use Disorders NCT03678051	Virginia Commonwealth University	N/A
Completed	Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence NCT03841292	Centre for Addiction and Mental Health	N/A
Completed	Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use NCT03842436	Brigham and Women's Hospital	Phase 4
Terminated	The Impact of a Parenting Intervention on Latino Youth Health Behaviors NCT03517111	Arizona State University	N/A
Completed	BA Trial for Co-Occurring Depression and Substance Use NCT03661580	University of Sheffield	N/A
Completed	Cardiac Surgery Peer Recovery Support Program NCT03590106	University of Rochester	N/A
Unknown	EMDR Versus Treatment As Usual in Patients With Substance Use Disorder NCT03517592	Parc de Salut Mar	N/A
Unknown	Addiction in Adolescence - Pathomechanisms and Treatment Evaluation NCT03444974	Technische Universität Dresden	N/A
Completed	Patient Centered Assessment and Substance Use Disorder Treatment Study (PCAST) NCT03486028	RTI International	—
Completed	ZOlpidem and the stRengthening of pRescription regulatiOn NCT03584542	Nantes University Hospital	—
Completed	Controlled Trial of Brexpiprazole For The Treatment of Co-occurring Schizophrenia and Substance Use Disorder NCT03526354	University of Massachusetts, Worcester	Phase 4
Completed	A Trauma Informed Adaptation of Mindfulness-Based Relapse Prevention for Women in Substance Use Treatment NCT03505749	Pacific University	N/A
Unknown	SMART Brain Health in African-Americans NCT03861832	Howard University	N/A
Completed	Substance Misuse To Psychosis for Ketamine (SToP-K) NCT03485339	The University of Hong Kong	—
Completed	Web-based Addiction Treatment: Cultural Adaptation With American Indians NCT03363256	New York State Psychiatric Institute	N/A
Unknown	Emotional Intelligence in Patients With Addictive Disorder NCT03521609	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	N/A
Completed	Homeless Care Management App NCT03399500	University of Oklahoma	Phase 3
Completed	Enhancing Adolescent Substance Abuse Treatment NCT03249350	Oregon Social Learning Center	N/A
Completed	Inpatient Link to Addiction Recovery NCT04098601	Prisma Health-Upstate	N/A
Active Not Recruiting	Tapering From Long-term Opioid Therapy in Chronic Pain Population. Randomized Controlled Trial With 12 Months NCT03485430	Lund University Hospital	N/A
Completed	Project POINT: Effectiveness and Scalability of an Overdose Survivor Intervention NCT03336268	Indiana University	N/A
Recruiting	rTMS for Craving in Methamphetamine Use Disorder NCT03470480	Oregon Health and Science University	N/A
Suspended	Physical Activity as Adjunct Treatment for Opioid Substitution Therapy NCT04496934	Haukeland University Hospital	N/A
Completed	Activating Community Support for Substance Users NCT03194295	Johns Hopkins University	Phase 2

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