NCT05764213

Improving Maternal Mental Health & SUD Screening and Treatment

Improving Maternal Mental Health & Substance Use Disorder Screening and Treatment

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10,470 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to compare a text message-based mental health and substance use screening and referral to a treatment program, called Listening to Women and Pregnant and Postpartum People (LTWP), to standard of care in-person mental health and substance use screening to look at rates of treatment attendance and retention in treatment. Participation would involve completing online questionnaires. You may be eligible to participate if you are age 18-45 years, are pregnant and entering prenatal care in one of MUSC's OB clinics, and attended a prenatal appointment at an MUSC clinic.

Detailed description

Aim 1: To determine differences in rates of treatment attendance and retention for Perinatal Mood and Anxiety Disorders (PMADs) and Perinatal Substance Use Disorders (PSUDs) between participants assigned to LTWP, compared to SBIRT. Aim 2: To determine differences in Patient-Reported Outcomes (PROs) including depressive symptoms, quality of life, substance use, and maternal functioning and well-being measured at baseline and 2, 5, 8, and 11 months postpartum.

Conditions

• Mental Health Issue
• Substance Use Disorders
• Postpartum Depression
• Postpartum Anxiety

Interventions

Type	Name	Description
BEHAVIORAL	Listening to Women & Pregnant and Postpartum People	Participants are enrolled in text message-based screenings with immediate automated feedback, paired with remote care coordination and, if appropriate, home-based telemedicine mental health and substance use disorder treatment services.

Timeline

• Start date: 2023-04-03
• Primary completion: 2027-07-31
• Completion: 2027-10-01
• First posted: 2023-03-10
• Last updated: 2026-04-08

Locations

1 site across 1 country: United States