| Not Yet Recruiting | Whole-Body Hyperthermia for Mood and Anxiety Disorders NCT06144294 | Weill Medical College of Cornell University | N/A |
| Not Yet Recruiting | Midwife-Led Digital Follow-Up After Cesarean Section NCT07523932 | Inonu University | N/A |
| Not Yet Recruiting | Implementation of a Clinical Decision Support Tool for Postpartum Depression NCT06818734 | Weill Medical College of Cornell University | N/A |
| Not Yet Recruiting | Efficacy of Yoga-Based Intervention in Improving Mother-Child Bonding in Maternal Depression NCT07515222 | All India Institute of Medical Sciences | N/A |
| Not Yet Recruiting | The Effect of Art-Based Mandala Coloring Activity on Postpartum Anxiety and Postpartum Depression NCT07312812 | Afyonkarahisar Health Sciences University | N/A |
| Enrolling By Invitation | Effect of Listening to Surah Al-Inshirah (The Opening-Up of the Heart) After Cesarean Birth on Postpartum Outc NCT07354334 | Selcuk University | N/A |
| Recruiting | A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone NCT07398469 | Biogen | — |
| Not Yet Recruiting | Postpartum 1-Day CBT Pilot Study (Türkiye) NCT07267702 | Marmara University | N/A |
| Completed | The Effect of Psychodramatic Role-Playing on Postpartum Depression, Self-Efficacy, and Perceived Social Suppor NCT07506759 | Istanbul University - Cerrahpasa | N/A |
| Withdrawn | The Perinatal Synergistic Multi-component Intervention to alLeviate dEpressive Symptoms. A Case Series NCT06048263 | Washington University School of Medicine | Phase 2 / Phase 3 |
| Completed | Psychoeducational Intervention to Reduce Depressive Symptoms and Strengthen Mother-Infant Bonding NCT07062159 | Yasemin Ozhuner | N/A |
| Withdrawn | Prevention of Postpartum Depression: A Pilot Placebo-controlled Trial of Trazodone NCT05299398 | Verinder Sharma | Phase 1 |
| Recruiting | Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery NCT06767566 | Grace Lim, MD, MS | Phase 1 |
| Active Not Recruiting | Prenatal Yoga to Prevent Postpartum Depression NCT06004232 | Henry Ford Health System | N/A |
| Recruiting | Improving Maternal Sleep and Mental Health NCT06544941 | University of Colorado, Colorado Springs | N/A |
| Not Yet Recruiting | Sleep, Oxytocin and Reward Processing in Women in the Postpartum Phase NCT06711809 | International Research Training Group 2804 | — |
| Recruiting | MamaConecta: Digital Tool for Maternal Mental Health NCT06442774 | A Thousand Colibris, S.L | N/A |
| Recruiting | Admission to Kangaroo Mother Care (KMC) Ward and Maternal Postpartum Depression NCT06545760 | University of Alabama at Birmingham | N/A |
| Recruiting | Understanding the Role of Doulas in Supporting People With PMADs NCT05763537 | University of Montana | N/A |
| Completed | Psychoeducatıon Interventıon Postpartum Depressıon Breastfeedıng NCT06779903 | Eskisehir Osmangazi University | N/A |
| Recruiting | COntact RElationship in Neonatal Intensive Care Unit NCT06462638 | Istituto per la Ricerca e l'Innovazione Biomedica | — |
| Active Not Recruiting | Smartphone Application to Support Mothers at Risk of Postpartum Depression NCT07167654 | Jordan University of Science and Technology | N/A |
| Recruiting | MBSR and NLP, Postpartum Breastfeeding and Depression NCT06628986 | Aysegul Kilicli | N/A |
| Unknown | Feasibility Evaluation of a Dance Fitness Program NCT06273423 | Montana State University | N/A |
| Active Not Recruiting | Public Health Nurse-Peer Co-Led Group Cognitive Behavioral Therapy for Postpartum Depression NCT06597448 | McMaster University | N/A |
| Recruiting | Postpartum Care in the NICU (PeliCaN) Transitions NCT06521398 | University of Pennsylvania | N/A |
| Active Not Recruiting | Efficacy of MI078 Capsules in Treating Postpartum Depression NCT06963580 | Nanjing Minova Pharmaceutical Co., Ltd. | Phase 2 |
| Not Yet Recruiting | Quetiapine Versus Trazadone in Women With Postpartum Depression NCT06546358 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | EARLY_Phase 1 |
| Not Yet Recruiting | Feasibility Study: Self-guided iCBT for Mothers With Postpartum Depression. NCT06569875 | University of Southern Denmark | N/A |
| Completed | A Postpartum Adaptation Study of the Connecting and Reflecting Experience Parenting Program NCT06042166 | Montefiore Medical Center | N/A |
| Unknown | Vitamin B6 and Depression in Pregnant and Peri-partum Women NCT06445933 | National Taiwan University Hospital | N/A |
| Recruiting | The Mom and Infant Outcomes (MOMI) Study NCT06277661 | Ohio State University | N/A |
| Completed | RE104 Safety and Efficacy Study in Postpartum Depression NCT06342310 | Reunion Neuroscience Inc | Phase 2 |
| Active Not Recruiting | Essential Coaching for Every Mother in Tanzania NCT05362305 | IWK Health Centre | N/A |
| Active Not Recruiting | Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention NCT06365645 | Women and Infants Hospital of Rhode Island | N/A |
| Unknown | Dose Low Dose Ketamine in Casesarian NCT06237569 | Inonu University | — |
| Suspended | Postpartum Video Education in High Risk Populations NCT06310720 | Weill Medical College of Cornell University | N/A |
| Recruiting | Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health NCT06379074 | University of Rome G. Marconi | N/A |
| Not Yet Recruiting | Mobile-Based Exercise in Postpartum Period NCT06390540 | Ankara University | N/A |
| Not Yet Recruiting | LoVE4MUM: Virtual Engagement for Preventing Postpartum Depression NCT06366035 | National Institutes of Health, Ministry of Health Malaysia | N/A |
| Completed | A Study to Assess the Efficacy, Safety, and Tolerability of Oral NORA520 in Adults With Severe Postpartum Depr NCT06285916 | DuKang Pharmaceuticals, Inc. | Phase 2 |
| Completed | Effect of Targeted Health Education Program on Nurses' Awareness About Postpartum Depression NCT06424496 | Ain Shams University | N/A |
| Completed | Improving Health Outcomes and Equity by Targeting Postpartum Mothers at Highest Risk NCT06276647 | University of Pennsylvania | N/A |
| Completed | Daring Birth - Digital Coaching Solution to Improve Childbirth Experience NCT06585839 | Aalto University | N/A |
| Completed | The Meleis Theory on Postpartum Depression, Breastfeeding, and Maternal Self-Efficacy in Women Experiencing Pr NCT06250933 | Bilecik Seyh Edebali Universitesi | N/A |
| Withdrawn | Carrying for the Culture NCT06148831 | Nurturely | N/A |
| Unknown | Postpartum Screening for Anxiety and Comorbid Conditions NCT06242717 | University of British Columbia | — |
| Enrolling By Invitation | Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression NCT06221280 | Kahramanmaras Sutcu Imam University | N/A |
| Completed | The Effect of Baby Massage Training Given to Pregnant Women on Maternal Attachment and Postpartum Depression NCT06136520 | Istanbul University - Cerrahpasa | N/A |
| Recruiting | Gestational Diabetes and Perinatal Depression: an Intervention Program NCT05800509 | National Taiwan University Hospital | N/A |
| Recruiting | Preventing Postpartum Depression in Immigrant Latinas NCT05873569 | Northwestern University | N/A |
| Recruiting | Rosie the Chatbot: Leveraging Automated and Personalized Health Information Communication NCT06053515 | University of Maryland, College Park | N/A |
| Completed | Early Half Swaddling and Kangaroo Care Practices on Maternal Sleep Quality and Postpartum Depression in Term B NCT06348316 | Trakya University | N/A |
| Completed | A Study on the Safety, Pharmacokinetics, and Food Effects of MI078 Capsules NCT06982651 | Nanjing Minova Pharmaceutical Co., Ltd. | Phase 1 |
| Active Not Recruiting | Effect of Low-dose Esketamine on Maternal Depression at 3 Years After Childbirth NCT05698394 | Peking University First Hospital | Phase 4 |
| Completed | Mindful Moms: Mechanisms of Mindfulness-based Cognitive Therapy During Pregnancy and Postpartum NCT05137925 | University of Pittsburgh | N/A |
| Unknown | A Phase II Study of HS-10353 in Participants With Postpartum Depression NCT05937867 | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Phase 2 |
| Active Not Recruiting | Improving Cognition and Gestational Duration With Targeted Nutrition NCT05949190 | Washington University School of Medicine | N/A |
| Recruiting | The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Wo NCT06737055 | Rhode Island Hospital | N/A |
| Recruiting | Parenting Skills Group for Mothers With Postpartum Depression NCT05772897 | University of Colorado, Denver | N/A |
| Completed | Screening of Postpartum Depression in Egyptian Women NCT05997953 | Al-Azhar University | — |
| Recruiting | Mother-infant Bonding in the Brain: a Mindfulness-based Intervention NCT05830266 | Tilburg University | N/A |
| Recruiting | The ROSE Scale-up Study: Informing a Decision About ROSE as Universal PPD Prevention NCT05700760 | Michigan State University | N/A |
| Withdrawn | rTMS for Peripartum Depression NCT03949465 | University of Calgary | N/A |
| Completed | The Effect of Lullaby and Breastmilk Smell on Preterm Newborns NCT05830955 | Mustafa Kemal University | N/A |
| Completed | A Study of BRII-297 in Healthy Adult Subjects NCT05845840 | Brii Biosciences Limited | Phase 1 |
| Recruiting | Effects of Epidural Labor Analgesia With Esketamine on the Incidence of Postpartum Depression in Parturients NCT05826327 | Women's Hospital School Of Medicine Zhejiang University | Phase 4 |
| Recruiting | Maternal Mental Health Access - MaMa NCT06049433 | University of Utah | N/A |
| Active Not Recruiting | Improving Maternal Mental Health & SUD Screening and Treatment NCT05764213 | Medical University of South Carolina | N/A |
| Unknown | Curio Digital Therapy for the Treatment of Post-partum Depression NCT05958095 | Healthcare Innovation Technology Lab | N/A |
| Recruiting | In-person vs. Virtual Delivery of a Group-based Prevention of Postpartum Depression NCT05766475 | University of Denver | N/A |
| Terminated | Phase 2 Clinical Trial of GH001 in Postpartum Depression NCT05804708 | GH Research Ireland Limited | Phase 2 |
| Withdrawn | A Six-Month Prospective Follow-Up Study of WB001 NCT05693792 | Woebot Health | — |
| Unknown | The Effect of Peripartum Magnesium Sulfate Use on the Occurrence of Postpartum Depression NCT05751746 | Seoul National University Bundang Hospital | — |
| Recruiting | Maternal Well-being in the Postnatal Stage NCT05676918 | Universidad Complutense de Madrid | N/A |
| Unknown | Prenatal Affective Cognitive Training to Reduce the Risk of Postpartum Depression (PACT) NCT06046456 | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | N/A |
| Completed | Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms: Impact on Child Developmen NCT05400161 | Children's Hospital of Philadelphia | N/A |
| Terminated | [Study Evaluating the Efficacy and Safety of a Digital Therapeutic as an Adjunct to TAU in Postpartum Depressi NCT05551195 | Woebot Health | N/A |
| Recruiting | Non-invasive Detection of Iron Deficiency in Obstetrics NCT07083492 | Wuerzburg University Hospital | — |
| Active Not Recruiting | Online 1-Day CBT-Based Workshops for Preventing Postpartum Depression NCT05753176 | McMaster University | N/A |
| Recruiting | Engage & Connect: A Psychotherapy for Postpartum Depression NCT05585164 | Weill Medical College of Cornell University | N/A |
| Recruiting | Neuraxial Labor Analgesia and Offspring Neurodevelopment NCT04964206 | Dong-Xin Wang | — |
| Completed | Public Health Nurse-Delivered 1-Day CBT Workshops for PPD NCT05622305 | McMaster University | N/A |
| Completed | Dynamic Neural Mechanisms of Brexanolone-induced Antidepressant Effects in Postpartum Depression NCT05543746 | University of North Carolina, Chapel Hill | — |
| Completed | Nutrition and Physical Activity Intervention on Psychosocial Well-Being of Postpartum Mothers NCT05444179 | Universiti Teknologi Mara | N/A |
| Completed | Mother-Child Interactions During Feeding NCT05664529 | Marmara University | — |
| Completed | Postpartum Video Education NCT05159726 | Yale University | N/A |
| Terminated | Effect of Consuming a Combination of Probiotic Strains on Postpartum Depression NCT06651424 | Biosearch S.A. | N/A |
| Active Not Recruiting | CBT for Postpartum Depression and Infant Emotion Regulation NCT05269732 | McMaster University | N/A |
| Completed | Virtual Group Psychoeducational Discussions With Spanish-Speaking Mothers of Infants in Pediatric Primary Care NCT05423093 | Johns Hopkins University | N/A |
| Completed | Distant Reiki Therapy on Postpartum Period Fatigue and Depression NCT06364436 | Aksaray University | N/A |
| Completed | 1 Day Workshops for Preventing PPD: A Pilot Study NCT05040581 | McMaster University | N/A |
| Active Not Recruiting | The Maternal Well-Being Study NCT05484999 | Texas Tech University Health Sciences Center | N/A |
| Completed | The SUPPORT Study: Effectiveness and Usability of a Web-Enabled Resource for Postpartum Mental Health NCT05382884 | University of British Columbia | Phase 2 |
| Unknown | bBeAMom: Effectiveness of a Cognitive-Behavioral Blended Intervention for Postpartum Depression NCT04441879 | University of Coimbra | N/A |
| Completed | Online Peer-Delivered Group CBT for PPD NCT05044455 | McMaster University | N/A |
| Active Not Recruiting | The Safety, Tolerability, and Effectiveness of Quetiapine in Postpartum Depression NCT04950868 | Verinder Sharma | Phase 1 |
| Completed | Public Health Nurse-Delivered 1-Day CBT Workshops Pilot NCT05314361 | McMaster University | N/A |
| Completed | The Effect of Colic Massage and Kangaroo Care on Babies and Their Mothers NCT06727760 | Gulsah Sunay Ertem | N/A |
| Completed | MomMoodBooster VA Program NCT05196152 | University of Iowa | N/A |
| Unknown | EEG Alterations of Uterine Contractions in the First Stage of Labor Predicting Postpartum Depression NCT05217251 | Zhujiang Hospital | — |
| Unknown | Effects of Esketamine on Postpartum Depression NCT05229913 | Qinghai University | Phase 4 |
| Recruiting | RCT of At-Home tDCS for Depression in Pregnancy NCT05097586 | Women's College Hospital | N/A |
| Unknown | Postpartum Depression and Maternal Attachment NCT05038085 | Gazi University | N/A |
| Completed | A Study To Assess The Safe-Use Conditions For Administration of ZULRESSO® in a Home Setting NCT05059600 | Supernus Pharmaceuticals, Inc. | Phase 4 |
| Completed | Yoga in the NICU for Parents Study NCT05322161 | Seattle Children's Hospital | N/A |
| Unknown | The Effects of Motherly on Postpartum Depression NCT05055674 | University of Sao Paulo | N/A |
| Completed | Virtual Reality Biofeedback for Postpartum Anxiety and Depression NCT04925765 | Grace Lim, MD, MS | N/A |
| Completed | A Pilot Trial of the Reach Out, Stay Strong, Essentials for Mothers of Newborns (ROSE) Postpartum Depression P NCT05225025 | University of Rochester | N/A |
| Completed | Postpartum Massage Therapy for Women and Infants: The Effect on Maternal Depression, Stress, Fatigue and Infan NCT06377176 | National Taipei University of Nursing and Health Sciences | N/A |
| Completed | Online Peer-Delivered 1-Day CBT Workshops for PPD NCT04934488 | McMaster University | N/A |
| Completed | Effects of Postpartum Nurse Navigation Program NCT05225987 | Hacettepe University | N/A |
| Completed | Esketamine on Postpartum Depression in Cesarean Section Women NCT04860661 | Ailin Luo | N/A |
| Recruiting | Mothers and Babies Qatar (MB-Q): A Postpartum Depression Intervention NCT04442529 | Sidra Medicine | N/A |
| Recruiting | Maternal Stress on Human Milk and Infant Outcomes NCT04821544 | University of Idaho | N/A |
| Completed | A Pilot Randomized Trial of Video-based Family Therapy for Depressed Home Visited Mothers NCT04741776 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | Effect of Laughter Yoga Therapy on Postpartum Depression NCT05133583 | Adiyaman University Research Hospital | N/A |
| Unknown | The Effect of Tele-Health Education Provided in the Postpartum Period in the Covid 19 Pandemic NCT04847362 | Saglik Bilimleri Universitesi | N/A |
| Recruiting | Stories That Empower Mothers and Postpartum Depression NCT06787300 | Ege University | N/A |
| Completed | Online Postpartum Follow-up on Depression and Postpartum Adaptation NCT05356026 | Gazi University | N/A |
| Unknown | Whether Probiotics Use in Neonate and Infant Improve Their Mother's Life Quality NCT04741971 | Buddhist Tzu Chi General Hospital | N/A |
| Recruiting | Maternal Mental Health Trial NCT04685148 | Vibe G Frøkjær, MD, PhD | Phase 1 / Phase 2 |
| Completed | Postpartum Visit Timing and the Effect on Visit Attendance NCT05399784 | Women and Infants Hospital of Rhode Island | N/A |
| Completed | IPT-G for Mums With Postpartum Depression NCT04580901 | McMaster University | N/A |
| Completed | Postnatal mHealth Intervention Development NCT04636398 | University of California, San Francisco | N/A |
| Completed | Postpartum Wellness NCT04414696 | Kaiser Permanente | N/A |
| Completed | Ketamine to Prevent PPD After Cesarean NCT04227704 | Washington University School of Medicine | Phase 3 |
| Completed | Pivotal Test: WB001 NCT04576754 | Woebot Health | N/A |
| Completed | Personalized Integrated Chronotherapy for Perinatal Depression NCT04364646 | Rhode Island Hospital | N/A |
| Unknown | Remote Peer Support in Prevention of Postpartum Depression NCT04639752 | National Institute of Mental Health, Czech Republic | N/A |
| Unknown | Online MBI for Families Affected by PPDA NCT04617132 | British Columbia Children's Hospital | — |
| Completed | Peer Administered Online CBT for PPD NCT04913584 | McMaster University | N/A |
| Unknown | Screening for Postpartum Depression and Associated Risk Factors Among Women Who Deliver in Four Hospital in Fr NCT04487171 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | Postpartum Depression in the Covid-19 Pandemic and the Impact of Anaesthesia NCT04437342 | General and Maternity Hospital of Athens Elena Venizelou | — |
| Completed | Low-dose S-ketamine in Women With Prenatal Depression NCT04414943 | Peking University First Hospital | N/A |
| Completed | Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression NCT03927378 | Peking University First Hospital | N/A |
| Completed | Brief Internet-Based Acceptance and Commitment Therapy Intervention for Parents in the Postpartum NCT05173285 | Hannah Palma Carlos | N/A |
| Unknown | Willkommen Mutterglück: Online CBT for Pregnant and Postpartum Women With Depression and Anxiety NCT04183946 | University of Zurich | N/A |
| Withdrawn | Keeping Well:Online Cognitive Behavioral Therapy (CBT) for Pregnant Women With Depressive Symptoms NCT01909167 | Imperial College London | N/A |
| Completed | Effect of Mother's Push at Cesarean Delivery Mother's PUSHING AT CS A RANDOMIZED CONTROLLED TRIAL NCT05520580 | Hannover Medical School | N/A |
| Completed | Online 1-Day CBT-Based Workshops for PPD NCT04485000 | McMaster University | N/A |
| Completed | Birth Experience During COVID-19 Confinement NCT04348929 | Central Hospital, Nancy, France | N/A |
| Completed | Online PHN CBT for PPD NCT04928742 | McMaster University | N/A |
| Unknown | Postpartum Depression NCT04278456 | Erzincan University | — |
| Withdrawn | A Study to Evaluate Multimodal Neuroimaging Parameters in Women With Postpartum Depression Who Are Receiving Z NCT04273191 | Sage Therapeutics | Phase 4 |
| Completed | Lactation Achievement With Texts at Home NCT04108533 | University of Pennsylvania | N/A |
| Unknown | The Effect of Early Dyadic Psychotherapy for Mothers Suffering From PPD on Oxytocin Level and on Childrens' Em NCT04138368 | HaEmek Medical Center, Israel | N/A |
| Completed | Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms NCT04045132 | Children's Hospital of Philadelphia | N/A |
| Completed | Prenatal Depression Prevention Effects on Parenting and Young Child Self-Regulation and Functioning NCT04296734 | Northwestern University | — |
| Completed | Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal Delivery NCT04017442 | Icahn School of Medicine at Mount Sinai | Phase 4 |
| Completed | Ketamine to Improve Recovery After Cesarean Delivery - Part 1 NCT04037085 | Grace Lim, MD, MS | Phase 2 |
| Withdrawn | Pacifiers and Breastfeeding Among Mothers at Risk for Postpartum Depression NCT03709004 | University of California, Davis | N/A |
| Completed | Nurtured in Nature NCT04146025 | University of Pennsylvania | N/A |
| Completed | Telephone Coaching Intervention for Postpartum Depression and Anxiety NCT04073043 | McGill University | N/A |
| Completed | The Impact of a Newborn Behavioral Intervention on the Mental Health of Mothers With Late Pre-Term Infants NCT03836430 | Brigham and Women's Hospital | N/A |
| Completed | The Relationship Between Oxytocin Level and Postpartum Depression NCT04427410 | Cukurova University | — |
| Completed | Intervention for IPV-exposed Pregnant Women NCT04068662 | University of Notre Dame | N/A |
| Completed | Emotional Freedom Techniques (EFT) and Postpartum Depression NCT04355091 | Istanbul University - Cerrahpasa | N/A |
| Unknown | Factors and Outcomes Associated With Postpartum Cabergoline Use NCT03965572 | Laniado Hospital | — |
| Completed | Happy Mother-Healthy Baby: An Anxiety-focused Early Prenatal Intervention NCT03880032 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Completed | Development of Postnatal Mobile Support Application NCT03415321 | Necmettin Erbakan University | N/A |
| Terminated | Mindfulness Based Cognitive Therapy (MBCT) During Pregnancy NCT03809572 | Oregon Health and Science University | N/A |
| Completed | Proactive, Personalized Postpartum Mental Healthcare NCT03803189 | Women's College Hospital | N/A |
| Completed | Northwell Health Visits: A Family Connects Pilot Implementation at Northwell Health NCT03887910 | Northwell Health | N/A |
| Completed | Early Diagnosis of PPD Through Self-portraits NCT03791021 | Sheba Medical Center | — |
| Unknown | The Effects of Pregnancy Classes and Contributing Factors to Postpartum Depression NCT03763435 | Bartin State Hospital | — |
| Completed | Coparenting Intervention to Prevent Postpartum Depression NCT06305325 | Brock University | N/A |
| Completed | Does Enhancing Maternal Peer Interactions Decrease Rates of Postpartum Depression? NCT03793569 | Milton S. Hershey Medical Center | N/A |
| Completed | Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries NCT03470675 | Northwestern University | Phase 4 |
| Completed | Development, Feasibility and Acceptability of Fathers and Babies (FAB): A Pilot Study NCT03427528 | Northwestern University | N/A |
| Completed | Proyecto BEBE: The Effect of Babywearing Education on Breastfeeding Exclusivity NCT04376021 | Nurturely | N/A |
| Completed | Peer Administered CBT for PPD NCT03285139 | McMaster University | N/A |
| Completed | 1-Day CBT Workshops for PPD NCT03654261 | McMaster University | N/A |
| Completed | Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression NCT03336541 | Peking University First Hospital | Phase 4 |
| Completed | A Study of Pregnant and Postpartum Women With and Without Mood Disorders NCT03615794 | Johns Hopkins University | — |
| Unknown | Be a Mom: Effectiveness of a Web-based Preventive Intervention for Postpartum Depression NCT03024645 | University of Coimbra | N/A |
| Completed | Integrating Text Messages Into the Mothers and Babies Course NCT03420755 | Northwestern University | N/A |
| Unknown | Prevalence of Psychological Disorders After Immediate Postpartum Hemorrhage NCT03120208 | University Hospital, Clermont-Ferrand | N/A |
| Completed | A Study to Evaluate SAGE-217 in Participants With Severe Postpartum Depression NCT02978326 | Biogen | Phase 3 |
| Completed | Comparing the Effectiveness of Clinicians and Paraprofessionals to Reduce Disparities in Perinatal Depression NCT02979444 | Northwestern University | N/A |
| Unknown | A Culturally Appropriate Intervention for Preventing and Reducing Postpartum Depression NCT02862444 | Clalit Health Services | — |
| Completed | A Study to Evaluate Efficacy and Safety of SAGE-547 in Participants With Severe Postpartum Depression (547-PPD NCT02942004 | Supernus Pharmaceuticals, Inc. | Phase 3 |
| Completed | A Study to Evaluate Safety and Efficacy of SAGE-547 in Participants With Moderate Postpartum Depression (547-P NCT02942017 | Supernus Pharmaceuticals, Inc. | Phase 3 |
| Completed | Personality Style and Self Compassion in Postpartum Depression: An Online Prevention Study NCT02813174 | i4Health | N/A |
| Terminated | Adjunctive Use of Celecoxib in the Treatment of Bipolar Postpartum Depression NCT02726659 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 3 |
| Completed | Mobile Phone Based Peer Support to Prevent Postpartum Depression Among Adolescent Mothers NCT02818075 | University of Toronto | N/A |
| Completed | Serotonin, Leptin and Adiponectin Level in Patients With Postpartum Depression: Controlled Study NCT02682004 | Zeynep Kamil Maternity and Pediatric Research and Training Hospital | — |
| Completed | Evaluate SAGE-547 in Female Participants With Severe Postpartum Depression NCT02285504 | Supernus Pharmaceuticals, Inc. | Phase 2 |
| Unknown | Oxytocin and Dyadic Psychotherapy in the Treatment of Post Partum Depression NCT02191423 | Tel-Aviv Sourasky Medical Center | N/A |
| Completed | Social Media Intervention for Postpartum Depression NCT02355067 | Children's Hospital of Philadelphia | N/A |
| Terminated | Is Vitamin D Insufficiency and Deficiency Associated With Antepartum and Postpartum Depression? NCT02272387 | St. Luke's-Roosevelt Hospital Center | N/A |
| Completed | Determining Relationships Among Maternity Stress & Sleep NCT02133963 | University of North Carolina, Chapel Hill | — |
| Completed | Social Circumstances, Parenting Techniques, and Infant Development NCT02121496 | New York State Psychiatric Institute | N/A |
| Completed | The Effect of Early Versus Traditional Follow-Up on Breastfeeding Rates at 6 Months NCT02221895 | Madigan Army Medical Center | N/A |
| Completed | Integrated Chronotherapy for Perinatal Depression NCT02053649 | Rhode Island Hospital | N/A |
| Completed | Can Oxytocin Level Predict Postpartum Depression? NCT02020148 | Northwestern University | — |
| Completed | Task Sharing Counseling Intervention by Community Health Workers for Prenatal Depression in South Africa NCT01977326 | University of Cape Town | N/A |
| Completed | Study of Exposure to Stress, Postpartum Mood, Adverse Life Events, and Hormonal Function Among Latinas (SEPAH NCT01912833 | University of North Carolina, Chapel Hill | — |
| Completed | Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition NCT01762943 | University of North Carolina, Chapel Hill | N/A |
| Completed | Social Media, Teen Moms and PPD NCT01967394 | University of Louisville | N/A |
| Completed | Effect of Exercise and Wellness Interventions on Preventing Postpartum Depression NCT01883479 | University of Minnesota | N/A |
| Completed | Mommy-Baby Treatment for Perinatal Depression NCT01744041 | Washington University School of Medicine | N/A |
| Unknown | Prevalence of Postpartum Depression in Hospital Jose E. Gonzalez NCT01658098 | Hospital Universitario Dr. Jose E. Gonzalez | — |
| Unknown | PREVENTION OF POSTPARTUM DEPRESSION DEVELOPMENT IN WOMEN WITH VERY HIGH RISK NCT02323152 | Basque Health Service | N/A |
| Completed | Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers NCT01482832 | Women and Infants Hospital of Rhode Island | N/A |
| Completed | Interaction Between Genetic Factors and Maternal Stressors During Pregnancy in the Risk of Postpartum Depressi NCT01648816 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continua NCT01463202 | Beatrice Chen | Phase 4 |
| Unknown | An Evaluation and Factor Analysis for Maternal Mental Health NCT01423331 | Shin Kong Wu Ho-Su Memorial Hospital | — |
| Completed | Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression NCT01379781 | New York State Psychiatric Institute | N/A |
| Completed | Aripiprazole and Resistant Postpartum Depression NCT01386086 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 3 |
| Completed | Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depres NCT02661789 | Gitte Moos Knudsen | N/A |
| Completed | Pilot Trial of CenteringPregnancy With Mindfulness Skills NCT01646463 | University of California, San Francisco | N/A |
| Completed | Measuring and Reducing Excessive Infant Crying NCT01217658 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Multidisciplinary Model of Nurse Midwife NCT01935375 | Drexel University | N/A |
| Completed | Case Management Study for Postpartum Depression and Intimate Partner Violence NCT00560027 | Johns Hopkins University | N/A |
| Completed | Mindfulness-Based Cognitive Therapy for the Prevention of Perinatal Depressive Relapse/Recurrence NCT02387424 | University of Colorado, Boulder | N/A |
| Completed | Mother-Infant Intervention for Postpartum Depression and Associated Mother-Infant Relationship Dysfunction NCT02057627 | Spaulding Rehabilitation Hospital | N/A |
| Completed | Cognitive Behavioral Therapy Delivered Over the Internet for Women With Postpartum Depression NCT00942721 | Oregon Research Institute | Phase 1 |
| Completed | The Effect of Exercise on Preventing PostPartum Depression NCT00961402 | University of Minnesota | Phase 2 |
| Completed | Escitalopram (Lexapro) for the Treatment of Postpartum Depression NCT00833469 | Massachusetts General Hospital | Phase 4 |
| Completed | Perinatal Depression Treatment in a Pediatric Setting- Pilot Phase NCT00804739 | University of Rochester | N/A |
| Completed | Effectiveness of a Web-based Prevention Program for Postpartum Depression NCT00816725 | University of California, San Francisco | N/A |
| Completed | Postpartum Anemia and Postpartum Depression NCT00782912 | Unity Health Toronto | — |
| Completed | The Staying Well Study: An Open Trial of Mindfulness-Based Cognitive Therapy for the Prevention of Perinatal D NCT02391870 | University of Colorado, Boulder | N/A |
| Completed | Cognitive-Behavioral Therapy (CBT) in Women Discontinuing Antidepressant for Pregnancy NCT01453114 | Massachusetts General Hospital | N/A |
| Terminated | Postpartum Depression: Transdermal Estradiol Versus Sertraline NCT00744328 | Northwestern University | Phase 4 |
| Completed | Escitalopram in the Treatment of Postpartum Depression NCT01527474 | BC Women's Hospital & Health Centre | N/A |
| Completed | Quetiapine in the Treatment of Postpartum Depression (PPD) in Bipolar Disorder (BD), Type II NCT01527448 | BC Women's Hospital & Health Centre | N/A |
| Completed | Treatment of Postpartum Depression With Psychotherapy and Add-on Sertraline NCT01028482 | Tel-Aviv Sourasky Medical Center | N/A |
| Terminated | A Prospective Study of Postpartum Depression in Women With Major Depression NCT01328613 | National Institute on Aging (NIA) | — |
| Completed | Mothers Avoiding Depression Through Empowerment Intervention Trial NCT01312883 | Icahn School of Medicine at Mount Sinai | N/A |
| Withdrawn | Duloxetine for the Treatment of Postpartum Depression NCT00617045 | Yale University | N/A |
| Completed | Improving Health Outcomes for New Mothers and Babies NCT00360204 | Milton S. Hershey Medical Center | Phase 3 |
| Completed | Postpartum Depression and Cesarean Section NCT00370903 | Oklahoma State University Center for Health Sciences | — |
| Completed | Mom: Managing Our Mood, Part of The Family Help Program NCT00795652 | IWK Health Centre | Phase 2 |
| Completed | Effect of Home-Based Peer Support on Maternal-Infant Interaction and Postpartum Depression NCT00298311 | Canadian Research Institute for Social Policy | N/A |
| Unknown | Translating Research Into Practice for Postpartum Depression NCT00548743 | Olmsted Medical Center | N/A |
| Completed | Postpartum Depression Prevention Trial NCT00604604 | University of Toronto | N/A |
| Completed | Lexapro in the Treatment of Patients With Postpartum Depression NCT00277108 | University of Rochester | N/A |
| Terminated | Clinical Trial of Estrogen for Postpartum Depression NCT00059228 | National Institute of Mental Health (NIMH) | Phase 2 |
| Terminated | Screening Evaluation for Women With Postpartum Depression NCT00056901 | National Institute of Mental Health (NIMH) | — |
| Completed | Study of Home-Based Exercise to Alleviate Postpartum Depression NCT00384943 | McGill University | N/A |
| Completed | Postpartum Thyroid Measures and Mood NCT00565032 | Oklahoma State University Center for Health Sciences | — |
| Completed | The Role of Hormones in Postpartum Mood Disorders NCT00001481 | National Institute of Mental Health (NIMH) | Phase 2 |
| Approved For Marketing | Expanded Access Protocol of ZULRESSO™ (Brexanolone) Injection for Adult Patients With Postpartum Depression NCT03924492 | Supernus Pharmaceuticals, Inc. | — |