NCT04205487

PrEP Readiness Interventions for Supporting Motivation

PrEP Readiness Interventions for Supporting Motivation in Stimulant-Using Sexual Minority Men

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Florida International University · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The overarching goal of this formative research is to examine whether, and in what combination, contingency management (CM) and motivational interviewing (MI) can facilitate entry of stimulant-using men who have sex with men (MSM) into the pre-exposure prophylaxis (PrEP) care continuum.

Detailed description

In Stage 1, participants will be randomized to receive either: 1) three months of CM; or 2) two sessions of MI. All participants will be assessed at three months post-randomization for non-response. In Stage 2, a second randomization where non-responders (i.e., those who have not filled a PrEP prescription) are assigned to: 1) Switch to sequentially receive the other intervention (i.e., CM+MI or MI+CM); or 2) Continue with assessments only (i.e., CM-Only or MI-Only). All participants will complete a final assessment at 6 months.

Conditions

• HIV Infections
• Pre-exposure Prophylaxis
• Substance Use Disorders

Interventions

Type	Name	Description
BEHAVIORAL	Motivational Interviewing (MI)	Two motivational interviewing sessions focusing on stimulant use, sexual risk, and PrEP uptake will be delivered via Zoom.
BEHAVIORAL	Contingency Management (CM)	CM will include financial incentives for PrEP clinical evaluation and filling a PrEP prescription.

Timeline

• Start date: 2020-10-16
• Primary completion: 2023-07-20
• Completion: 2023-07-28
• First posted: 2019-12-19
• Last updated: 2025-06-29
• Results posted: 2025-06-29

Locations

1 site across 1 country: United States