NCT03338361

Research on the Efficacy of the "T.O.P. Computer Training" Procedure in the Treatment of Alcohol Dependence

Efficacy of Approach Avoidance and Attentional Bias Retraining in Alcohol-dependent Patients: a Randomized Controlled Trial in a Clinical Setting

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 247 (actual)
• Sponsor: University Ghent · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators evaluate the efficacy of a computerised program (T.O.P. tool) consisting of an approach avoidance training (AAT) (to retrain action tendencies for alcohol-related stimuli), a visual probe training (VPT) (to retrain attentional bias for alcohol-related stimuli) and the combination of both training procedures versus placebo training, as an add-on to treatment as usual (psycho-education and cognitive behavioral therapy). The investigators include hospitalized detoxified alcohol-dependent patients, who receive a four week training procedure, existing of a pre-assessment, 6 training sessions and a post-assessment. Outcome measures consist of behavioral measures (consumption of alcohol - self report over 1 year), questionnaires (AUDIT; craving on 9-point likert scale) and approach avoidance and visual probe measurement tasks. A six month and 1 year follow-up is included (behavioral measures and AUDIT). Further, the investigators will also assess credibility (9-point likert scale) of the training procedure before the start of the training and immediately after the assessment of the AAT and VPT training.

Conditions

• Alcohol Dependence

Interventions

Type	Name	Description
BEHAVIORAL	active approach avoidance training and sham visual probe training	patients receive active AAT training and sham VPT training
BEHAVIORAL	sham approach avoidance training and active visual probe training	patients receive sham AAT training and active VPT training
BEHAVIORAL	active approach avoidance training and active visual probe training	patients receive active AAT training and active VPT training
BEHAVIORAL	sham approach avoidance training and sham visual probe training	patients receive sham AAT training and sham VPT training

Timeline

• Start date: 2017-10-26
• Primary completion: 2020-02-29
• Completion: 2020-02-29
• First posted: 2017-11-09
• Last updated: 2021-12-21

Locations

1 site across 1 country: Belgium