Clinical Trials Directory

Trials / Completed

CompletedNCT02364947

A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
678 (actual)
Sponsor
Otsuka Pharmaceutical Co., Ltd. · Industry
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

The efficacy, safety, and dose-response of nalmefene hydrochloride at 10 mg and 20 mg in patients with alcohol dependence will be evaluated in a multicenter, randomized, double-blind, placebo-controlled, 3-parallel-group comparative trial. The superiority of nalmefene hydrochloride at 20 mg to placebo will be verified in terms of reduction of alcohol consumption.

Conditions

Interventions

TypeNameDescription
DRUGNalmefene hydrochlorideAs-needed; tablets, orally
DRUGPlaceboAs-needed; tablets, orally

Timeline

Start date
2015-02-09
Primary completion
2016-07-30
Completion
2016-07-30
First posted
2015-02-18
Last updated
2019-09-30
Results posted
2019-09-30

Locations

7 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT02364947. Inclusion in this directory is not an endorsement.