NCT00439049

Substance Abuse Pre-Treatment Screening Study

General Evaluation of Eligibility for Substance Abuse/Dependence Research

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 7,500 (estimated)
• Sponsor: The University of Texas Health Science Center, Houston · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for their presenting concerns or interests. A second purpose is to have a consolidated intake data base on which secondary analyses can be conducted.

Detailed description

Approximately 1500 candidates per year will respond to advertisements and will complete preliminary telephone screening without identifiers. Appropriate candidates will be given appointment times and on arrival will undergo the consent process for evaluation. A complete medical, social, psychiatric, and drug use history will be obtained. Subjects fulfilling general health inclusion requirements will then be offered an appropriate study for which the specific consent will be obtained. The evaluation period will be no more than one day with all results evaluated within the two following days. Acceptable candidates will then be invited to complete the study specific consent.

Conditions

• Cocaine Abuse
• Cocaine Dependence
• Opiate Dependence
• Alcohol Dependence
• Substance Abuse

Interventions

Type	Name	Description
DRUG	modafinil	400 mg daily
DRUG	d-amphetamine	60mg daily
DRUG	L-Dopa	800/200mg daily
DRUG	Naltrexone	50mg daily

Timeline

• Start date: 2005-10-01
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2007-02-22
• Last updated: 2023-12-20

Locations

1 site across 1 country: United States