| Recruiting | Neuroimaging of Adolescent Cannabis Use Treatment NCT07340554 | Indiana University | N/A |
| Not Yet Recruiting | Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved NCT07432555 | Temple University | N/A |
| Enrolling By Invitation | Senyo Health With Substance Use Disorder (SUD) in Primary Care NCT06743282 | Mayo Clinic | N/A |
| Recruiting | Feasibility of Long-term, High-dose Stimulant for Methamphetamine Use Disorder NCT06788587 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 2 |
| Recruiting | SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families NCT06627764 | Duke University | N/A |
| Not Yet Recruiting | Exploring Substance Use, Sleep Disturbances and Reward Sensitivity NCT07028346 | Kwai Chung Hospital | N/A |
| Recruiting | Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees NCT06899308 | Jacobs University Bremen gGmbH | — |
| Recruiting | The Trans-Led Care Study NCT06880705 | Illinois Institute of Technology | N/A |
| Recruiting | Data2Action Oregon Project: Supporting Data-driven Decision-Making for Substance Use Services, Policy, and Ove NCT06852170 | Chestnut Health Systems | N/A |
| Recruiting | Harm Reduction Services NCT05776316 | NYU Langone Health | N/A |
| Active Not Recruiting | The STop UNhealthy Substance Use Now Trial NCT06524232 | Ohio State University | N/A |
| Recruiting | Nurse-Led Heart Math Training Program With Substance Use Disorder NCT06437366 | Alexandria University | N/A |
| Recruiting | "Effectiveness of School-based Substance Abuse Prevention Programme Among Adolescents . NCT06004726 | Manipal College of Nursing | N/A |
| Terminated | Project BrEAtHe: A Culturally Tailored MBSR Intervention for Young Adult Black Men NCT07009977 | UConn Health | N/A |
| Unknown | Characterization of the Pattern of Consumption and Withdrawal Syndrome From Dual Cannabis and Tobacco Use NCT05512091 | Cristina Martínez Martínez | — |
| Unknown | tDCS and Impulsivity NCT05845164 | University of Arizona | N/A |
| Recruiting | Testing Strategies to Improve Substance Misuse Prevention Research Use in State Policy Contexts NCT06856148 | Penn State University | N/A |
| Active Not Recruiting | Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk NCT05657106 | April M Young | N/A |
| Unknown | Strengthening Families Program Online NCT04214327 | Strengthening Families Program LLC | N/A |
| Terminated | Electronic SBI(RT) for MSM in Argentina NCT05542914 | Florida State University | N/A |
| Completed | Data-driven Identification for Substance Misuse NCT03833804 | University of Wisconsin, Madison | N/A |
| Recruiting | Testing ALERT With GTO in Middle Schools NCT05219422 | RAND | N/A |
| Completed | Aerobic Exercise for Cognitive Functioning in Patients With Substance Use Disorder NCT05324085 | St. Olavs Hospital | N/A |
| Recruiting | Drug-free Without Toothache. A Study of Free Dental Treatment as a Part of Substance Abuse Treatment NCT05606562 | University Hospital of North Norway | N/A |
| Completed | Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among NCT05286879 | Yale University | N/A |
| Active Not Recruiting | Breathwork-assisted Treatment for Cannabis Use Disorder NCT05219825 | Elias Dakwar | N/A |
| Completed | A High School Program for Preventing Prescription Drug Misuse NCT03219190 | National Health Promotion Associates, Inc. | N/A |
| Recruiting | Functional Connectivity Alterations in Suicidal Patients Among Opioid Users NCT05489042 | Baylor College of Medicine | N/A |
| Completed | Preventing Substance Use Among Youth NCT04752189 | Wayne State University | N/A |
| Completed | Mental Health Associations With Vitiligo NCT04953338 | Momentum Data | — |
| Completed | Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-stud NCT03911739 | T. John Winhusen, PhD | — |
| Unknown | A Scaleable Video Coaching Intervention for Opioid-using Mothers NCT04749771 | University of Oregon | N/A |
| Unknown | Clinical Characteristics of Patients Referred to a Substance Abuse Liaison Department in an Academic Hospital, NCT04916028 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Feasibility of Mobile and Technology Assisted Aftercare Services for Crisis Stabilization Units NCT04899934 | Florida State University | N/A |
| Completed | Drug Abuse During the COVID-19 Pandemic. NCT04811352 | Instituto Mexicano del Seguro Social | — |
| Completed | Delivering Contingency Management in Outpatient Addiction Treatment NCT04544124 | University of Calgary | N/A |
| Suspended | CBD Oil for Reducing Emotional Impact of COVID-19 NCT04603781 | University of Texas at Austin | Phase 2 / Phase 3 |
| Completed | Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders NCT04556552 | Emory University | Phase 3 |
| Completed | Mental Health, Addictions and Biomarkers in High Athletes Performance NCT04842461 | Cardenal Herrera University | — |
| Completed | Medication Treatment for Opioid Use Disorder in Expectant Mothers NCT03918850 | T. John Winhusen, PhD | Phase 3 |
| Completed | Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study NCT03911466 | T. John Winhusen, PhD | — |
| Enrolling By Invitation | Cost-effectiveness of the Care Pathways NCT04619836 | Tampere University Hospital | — |
| Unknown | Reducing Stigma Toward Mental Illness and Substance Use Issues in Primary Health Care in Chile NCT05578066 | Pontificia Universidad Catolica de Chile | N/A |
| Unknown | Evaluation of Thiwáhe Gluwáš'Akapi Substance Use Prevention Program NCT04222556 | University of Colorado, Denver | N/A |
| Completed | Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia NCT03458039 | Centre for Infectious Disease Research in Zambia | N/A |
| Completed | Preventing Drug Abuse Among Sexual Minority Youth NCT03954535 | Columbia University | N/A |
| Completed | Brain Indices of Stimulant Treatment in Drug-Naive Youth at Risk for Substance Use Disorder NCT04170738 | Jeffrey Newcorn | Phase 4 |
| Unknown | Post-traumatic Stress Injuries Among Paramedics and Emergency Dispatchers NCT04202042 | Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal | N/A |
| Completed | To Reach Unrestricted Services for Transgender Women NCT03877497 | University of Central Florida | N/A |
| Unknown | EEG Monitoring in the Emergency Department NCT04070521 | Massachusetts General Hospital | — |
| Unknown | MBRP on Reducing Craving and Addictive Behaviour in Adults NCT04034732 | Chinese University of Hong Kong | N/A |
| Completed | The Effect of Self-Forgiveness on Self-Stigma in Addiction. NCT03971097 | University of Pittsburgh | N/A |
| Unknown | Perinatal Mental Health Care in Switzerland NCT04185896 | Bern University of Applied Sciences | — |
| Unknown | Recovery - a Collaborative Project NCT04138459 | University College of Southeast Norway | — |
| Completed | Hispanic Men Building Respect Education and Safety/ HoMBRES Manteniendo Respeto, Educacion y Seguridad. NCT03730987 | University of Miami | N/A |
| Completed | A Multiple Ascending Dose Study of Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers NCT04007263 | Neurop Inc. | Phase 1 |
| Unknown | Swift, Certain, and Fair: Reducing Recidivism and Improving Outcomes for Alcohol and Drug Users on State Parol NCT03826420 | Botec Analysis, LLC | N/A |
| Unknown | An Evaluation of the NJSPB SCF Project for Opioid-Involved High-Risk Parolees NCT03812484 | Botec Analysis, LLC | N/A |
| Completed | Substance Use Interventions for Truant Adolescents NCT03655574 | Brown University | N/A |
| Withdrawn | Can The Bridge Transition Opiate Use Disorder Patients in Stable Recovery From Buprenorphine to Naltrexone NCT03762798 | The Cleveland Clinic | N/A |
| Completed | CARESS: An Investigation of Effects of CARESS NCT03758027 | Inova Health Care Services | N/A |
| Completed | OPTIONS: A Patient-Centered HIV Prevention Decision Aid for PrEP Uptake for Women With Substance Use in Treatm NCT03651453 | Yale University | N/A |
| Completed | CBT4CBT for Women in Residential Treatment for Substance Use Disorders NCT03678051 | Virginia Commonwealth University | N/A |
| Completed | A Comparison of How Likely it is That Different Tablets of Oxycodone Will be Broken up and Snorted by Adults W NCT03765346 | Grünenthal GmbH | Phase 1 |
| Active Not Recruiting | Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders NCT03540745 | University of Arizona | N/A |
| Completed | Feasibility of Providing Computerized CBT in the Black Church NCT03579290 | Yale University | N/A |
| Unknown | Positive Effects of Laser Acupuncture in Methamphetamine Users Undergoing Group Cognitive Behavioral Therapy: NCT04789772 | Chang Gung Memorial Hospital | N/A |
| Completed | Integrated BA and HIV RR Counseling for MSM With Stimulant Abuse NCT03175159 | University of California, Los Angeles | N/A |
| Completed | A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Dat NCT02963948 | NYU Langone Health | — |
| Completed | Health and Justice: A Continuum of Care for HIV and SU for Justice-Involved Young Adults (PHASE 2) NCT03369249 | New York State Psychiatric Institute | N/A |
| Completed | Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs NCT03282890 | University of Connecticut | N/A |
| Completed | Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging NCT03751020 | Yale University | N/A |
| Completed | Increasing Caregiver Engagement in Juvenile Drug Courts NCT03051997 | Medical University of South Carolina | N/A |
| Completed | Teen Success Project NCT03015805 | Chestnut Health Systems | N/A |
| Completed | Computer-Assisted Brief Intervention NCT03107117 | Brown University | N/A |
| Completed | Enhancing Permanency in Children and Families NCT04700696 | Ohio State University | N/A |
| Completed | Master Mind Program Evaluation Study NCT03212066 | Innovation Research & Training | N/A |
| Recruiting | Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in Adolescent NCT06262958 | Kuopio University Hospital | N/A |
| Completed | Telephone Coaching of Family Members of Veterans With Substance Abuse Problems NCT03246646 | VA Office of Research and Development | N/A |
| Unknown | An Evidence-based Approach for Bullying Prevention NCT03205059 | National Health Promotion Associates, Inc. | N/A |
| Unknown | First Years Away From Home: Letting Go and Staying Connected NCT03227809 | Washington State University | N/A |
| Completed | Personalized Health Assessment Related to Medications (Project PHARM) NCT03037476 | University of Washington | N/A |
| Completed | CONNECT for Depressed Cannabis Users Trial NCT03727659 | University of California, Los Angeles | N/A |
| Completed | Efficacy of Centervention-ATOD: An Implementation Tool for Dissemination of Evidence-based Programs for Substa NCT03084406 | 3-C Institute for Social Development | N/A |
| Completed | A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses NCT02922959 | University of Cincinnati | N/A |
| Completed | Integrated Care (iCare) at Mount Sinai to Improve Substance Use Diagnosis and Treatment Practices in HIV Clini NCT03092596 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | Effects of Core Stabilization Exercises on Pulmonary Functions, Respiratory Muscle Strength and Functional Cap NCT03461614 | Istanbul University | N/A |
| Completed | Family Engagement, Cross-System Linkage to Substance Use Treatment for Juvenile Probationers -- Phase 3 NCT03048552 | New York State Psychiatric Institute | N/A |
| Completed | Computer Based Training in CBT in Primary Care NCT03013478 | Yale University | N/A |
| Withdrawn | Victim Impact Modules for Jail Inmates NCT01381146 | George Mason University | N/A |
| Completed | Woman Mental Health and Addictions on Pregnancy NCT06965270 | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | N/A |
| Completed | Accuracy & Usability Study for Soberlink Cellular Device NCT02794038 | Soberlink Healthcare LLC | N/A |
| Completed | A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Dat NCT02986841 | NYU Langone Health | — |
| Completed | A Clinical Decision Support Tool for Electronic Health Records NCT02697643 | Inflexxion, Inc. | N/A |
| Completed | Validating Adolescent SBIRT Measures NCT02981849 | Boston Children's Hospital | — |
| Terminated | Computer-assisted Delivery of Cognitive Behavioral Therapy for Mental Health and Addictions in Canada NCT03230669 | University of Prince Edward Island | N/A |
| Unknown | Preventing Prescription Drug Abuse in Middle School Students NCT03129334 | National Health Promotion Associates, Inc. | N/A |
| Completed | Implementation Research for Vulnerable Women in South Africa NCT02733003 | RTI International | N/A |
| Unknown | Optimizing a Drug Abuse Prevention Program for Dissemination NCT03125291 | Arizona State University | N/A |
| Completed | Understanding Substance Use and Incident HIV/STI Among Young Black MSM NCT02503618 | Emory University | — |
| Unknown | Primary Prevention of Sexual Violence Among College Students NCT03037866 | National Health Promotion Associates, Inc. | N/A |
| Completed | Mindfulness-Based Recovery in Veterans NCT02326363 | VA Office of Research and Development | N/A |
| Completed | Yappalli - The Road to Choctaw Health NCT02400554 | University of Washington | N/A |
| Completed | Implementing Screening for Cannabis and Other Drug Use Disorders in Primary Care: Impact on Diagnosis and Trea NCT06249542 | Kaiser Permanente | N/A |
| Completed | Feasibility of Interventions on People Who Inject Drugs in Vietnam NCT02573948 | ANRS, Emerging Infectious Diseases | — |
| Completed | Phone Interview to Prevent Recurring Opioid Overdoses NCT02282306 | University of Cincinnati | N/A |
| Completed | Linking Families Together Study- A Randomized Trial to Raise Parental Monitoring NCT02129153 | University of California, Los Angeles | N/A |
| Completed | Physician Coaching to Reduce Opioid-related Harms NCT02433496 | University of Wisconsin, Madison | — |
| Completed | Acquisition of Responses to a Methamphetamine-associated Cue in Healthy Humans NCT02323048 | University of Chicago | N/A |
| Completed | Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence NCT02111798 | Johns Hopkins University | Phase 2 / Phase 3 |
| Completed | Young Women's Health CoOp (Cooperative) in Cape Town NCT02677025 | RTI International | N/A |
| Completed | Testing a Promising Treatment for Youth Substance Abuse in a Community Setting NCT02130479 | Medical University of South Carolina | Phase 1 / Phase 2 |
| Completed | Family Listening Program: Multi-Tribal Implementation and Evaluation NCT03142009 | University of New Mexico | N/A |
| Completed | An Evaluation of JUST Court in Yuma County, AZ NCT02449057 | Pepperdine University | N/A |
| Completed | Parenting Mindfully Study NCT02038231 | George Mason University | N/A |
| Unknown | Working Memory Training in Adults With Substance Abuse and Executive Function Deficits. NCT02068261 | Örebro Läns Landsting | Phase 2 |
| Completed | Enhanced Access to HIV Care for Drug Users in San Juan, Puerto Rico NCT01792752 | Columbia University | N/A |
| Withdrawn | Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI) NCT01515917 | Deborah Yurgelun-Todd | N/A |
| Withdrawn | cSBI-M for Young Military Personnel NCT01847300 | Boston Children's Hospital | N/A |
| Withdrawn | Advancing Adolescent Screening and Brief Intervention Protocols in Primary Care Settings NCT01523444 | Treatment Research Institute | Phase 3 |
| Unknown | Computerized Stage-Matched Intervention for Juvenile Offenders NCT02023827 | Pro-Change Behavior Systems | Phase 2 |
| Unknown | Mobile Psychosocial Interventions for MMT Clients NCT01632982 | National Development and Research Institutes, Inc. | N/A |
| Unknown | Group Psychotherapy for Adolescents With Substance Use NCT02933125 | Chang Gung Memorial Hospital | N/A |
| Completed | Linking Former Inmates to Primary Care NCT01863290 | Yale University | — |
| Completed | Effect Evaluation of Individual Placement and Support (IPS) NCT01964092 | NORCE Norwegian Research Centre AS | N/A |
| Completed | An Integrated Treatment for Comorbid PTSD and Substance Abuse in Adolescents NCT01825694 | University of California, Los Angeles | N/A |
| Completed | Goal Setting for Health Behavior and Psychosocial Issues in Primary Care NCT01825746 | Virginia Commonwealth University | N/A |
| Completed | Carisbamate as a Potential Treatment for Alcohol Dependence NCT02435381 | Baylor College of Medicine | Phase 1 / Phase 2 |
| Completed | Parent-Adolescent Interactions and Adolescent Development NCT01572441 | George Mason University | — |
| Completed | Creatine as a Treatment Option for Depression in Methamphetamine Using Females NCT01514630 | Perry Renshaw | Phase 4 |
| Completed | Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users NCT01614106 | Columbia University | N/A |
| Completed | Targeting PM to Improve HIV Adherence in Adolescents at Risk for Substance Abuse NCT01959217 | Wayne State University | N/A |
| Completed | Reducing High Risk Behavior in Treatment Court NCT01481428 | Treatment Research Institute | Phase 1 |
| Completed | Cognitive Skills Training for Homeless Youth NCT01815398 | New York State Psychiatric Institute | N/A |
| Completed | Hospital Visit as Opportunity for Prevention and Engagement for HIV-Infected Drug Users NCT01612169 | Columbia University | N/A |
| Completed | Methadone Oxytocin Option NCT01728909 | University of California, San Francisco | EARLY_Phase 1 |
| Completed | WHC+ (Women's Health CoOp PLUS) NCT01497405 | RTI International | Phase 1 |
| Completed | Varenicline for Methamphetamine Dependence NCT01365819 | University of California, Los Angeles | Phase 2 |
| Completed | Impact of Personalized Feedback Alone on Substance Use Behaviors NCT01501318 | University of Missouri-Columbia | N/A |
| Completed | Computer Based Training in Cognitive Behavioral Therapy Web-based NCT01442597 | Yale University | Phase 1 / Phase 2 |
| Recruiting | Treatment Outcomes Under a Standardized Treatment Protocol in Patients Suffered Substance Abuse Related Voidin NCT03913819 | Chinese University of Hong Kong | — |
| Completed | "Effectiveness of a Brief Intervention for Substances Consumption Linked to the Alcohol, Smoking and Substance NCT01573416 | Pontificia Universidad Catolica de Chile | Phase 3 |
| Completed | Contingency Management for Persons With Severe Mental Illness NCT01478815 | UConn Health | N/A |
| Completed | Substance Treatment and HIV Testing and Referral System NCT01488630 | Polaris Health Directions | Phase 2 |
| Completed | Pramipexole as a Treatment for Cocaine Dependence NCT01651377 | Baylor College of Medicine | Phase 1 |
| Completed | Home-Based Program to Help Parents of Drug Abusing Adolescents NCT01591239 | Treatment Research Institute | N/A |
| Completed | Exercise as a Behavioral Treatment for Cocaine Dependence NCT01601743 | Baylor College of Medicine | N/A |
| Completed | A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV NCT01362634 | Nova Southeastern University | N/A |
| Completed | A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence NCT01651364 | Baylor College of Medicine | Phase 1 |
| Completed | Seek, Test, and Retain. Linkages for Black HIV+, Substance-Using MSM NCT01790360 | Columbia University | N/A |
| Completed | Fathers for Change for Men With Co-occurring Domestic Violence and Substance Abuse NCT01385553 | Yale University | Phase 1 / Phase 2 |
| Withdrawn | Improving Outcomes in Psychosis Associated With Substance Use Using Aripiprazole NCT01155544 | Northwell Health | Phase 4 |
| Unknown | Evaluation of Re-Entry Values and Mindfulness Program (REVAMP) With Jail Inmates NCT01378923 | George Mason University | Phase 1 / Phase 2 |
| Completed | Family-Based Treatment for Parental Substance Abuse and Child Maltreatment NCT01656837 | Medical University of South Carolina | N/A |
| Active Not Recruiting | Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care NCT01621711 | Kaiser Permanente | N/A |
| Completed | Improving Antihypertensive Medication Adherence NCT01296594 | UConn Health | N/A |
| Completed | fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults NCT01320748 | Inova Health Care Services | N/A |
| Completed | Neuromodulation to Facilitate the Effect of Ketamine NCT01816958 | The Neuroscience Center, LLC | — |
| Completed | Substance Use and Fitness NCT01305902 | UConn Health | N/A |
| Completed | Safety Interaction Trial Ibudilast and Methamphetamine NCT01217970 | University of California, Los Angeles | Phase 1 |
| Completed | Varenicline as a Treatment for Methamphetamine Dependence NCT01571167 | Baylor College of Medicine | Phase 1 |
| Completed | Family Training Program for Parents of Substance Using Adolescents NCT01344382 | Treatment Research Institute | Phase 1 / Phase 2 |
| Unknown | Clinical Intervention Psychosis and Addiction NCT01411566 | University of Cologne | EARLY_Phase 1 |
| Completed | Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse Treatment NCT01410110 | Yale University | Phase 2 |
| Completed | Substance Abuse and Trauma in Incarcerated Women NCT01413984 | University of Tulsa | N/A |
| Completed | Auricular Acupuncture in Substance Abuse: Effects on Anxiety, Sleep, Drug Use. NCT02604706 | Örebro Läns Landsting | Phase 2 |
| Completed | Efficacy Trial of Warrior Check-Up NCT01128140 | University of Washington | Phase 2 |
| Unknown | Treatment of Intimate Partner Violence and Substance Abuse in a Forensic Setting NCT00847548 | VU University of Amsterdam | N/A |
| Withdrawn | Primary Care Internet-Based Depression Prevention for Adolescents (CATCH-IT) NCT01228890 | University of Chicago | Phase 3 |
| Completed | Building Outcomes With Observation-Based Supervision: An FFT Effectiveness Trial NCT01614015 | Oregon Research Institute | Phase 2 |
| Unknown | Hair Testing to Assess Consumption of Illicit Psychotropic Agents and Alcohol by Patients Treated With High-do NCT01285856 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Modafinil - Escitalopram Study for Cocaine Dependence NCT01601730 | Baylor College of Medicine | Phase 1 |
| Completed | Adherence to HIV Therapy in Heroin Addicts: Oral vs XR-NTX NCT01101815 | University of Pennsylvania | Phase 2 |
| Completed | Young Women's CoOp Study NCT01224184 | RTI International | N/A |
| Completed | Using Incentives to Improve Parolee Participation and Attendance in Community Treatment NCT01090245 | University of California, Los Angeles | N/A |
| Completed | Reinforcing Exercise in Substance Abusing Patients NCT01204879 | UConn Health | N/A |
| Completed | Web-delivery of Evidence-based, Psychosocial Treatment for Substance Use Disorders NCT01104805 | New York State Psychiatric Institute | N/A |
| Completed | Training Clinicians in Motivational Interviewing NCT01065480 | New York State Psychiatric Institute | N/A |
| Completed | Stonewall Treatment Evaluation Project NCT01129401 | University of California, San Francisco | Phase 1 / Phase 2 |
| Completed | NAC as a Potential Treatment for Methamphetamine Dependence NCT01063205 | Baylor College of Medicine | Phase 1 |
| Withdrawn | RTI-336 as a Treatment for Methamphetamine Dependence NCT01601717 | Baylor College of Medicine | Phase 1 |
| Completed | Evaluation of Web-Based Recovery Monitoring With Clinical Alerts NCT01465555 | Treatment Research Institute | Phase 1 / Phase 2 |
| Completed | Juvenile Offender HIV Prevention and Drug Abuse Services NCT01922297 | University of Miami | N/A |
| Completed | The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine NCT01062945 | Baylor College of Medicine | Phase 1 |
| Completed | Automated Telephone Follow-up in the Swedish Prison and Probation Services NCT01727882 | Region Skane | N/A |
| Completed | Screening Protocol for Research Participants NCT01010620 | University of Maryland, Baltimore | — |
| Unknown | ENGAGE - Meeting Mental Health Needs of Complex Comorbid Patients NCT00980824 | University of Glasgow | Phase 1 / Phase 2 |
| Completed | Varenicline vs Placebo for the Treatment of Methamphetamine Dependence NCT01011829 | University of California, Los Angeles | Phase 2 |
| Completed | Treatment of Intimate Partner Violence and Substance Abuse in a Substance Abuse Treatment Facility NCT00847873 | VU University of Amsterdam | N/A |
| Completed | The Men's Domestic Abuse Check-Up Engages Adult Men Concerned About Their Abusive Behavior and Alcohol or Drug NCT01621334 | University of Washington | Phase 1 |
| Unknown | Jail-Based Impact of Crime Intervention NCT01378936 | George Mason University | Phase 2 |
| Completed | Adolescent Involvement in Parental Substance Abuse Treatment NCT01576393 | Ohio State University | Phase 1 / Phase 2 |
| Completed | Multicomponent Cognitive Behavioral Therapy(CBT) for Posttraumatic Stress Disorder (PTSD) and Substance Abuse NCT01029197 | University of North Carolina, Chapel Hill | Phase 1 |
| Completed | Rivastigmine as a Treatment for Methamphetamine Dependence NCT01073319 | Baylor College of Medicine | Phase 1 |
| Completed | Substance Abuse Treatment for High Risk Chronic Pain Patients on Opioid Therapy NCT00988962 | Brigham and Women's Hospital | N/A |
| Completed | An ACE Inhibitor (Perindopril) or an Angiotensin Receptor Blocker (Candesartan) as a Treatment for Methampheta NCT01062451 | Baylor College of Medicine | Phase 1 |
| Completed | Stage 1 Treatment Development With Homeless Mothers NCT01193114 | Ohio State University | N/A |
| Completed | Psychopharmacotherapy in Multiple Substances Abuse NCT01189214 | National Cheng-Kung University Hospital | Phase 3 |
| Completed | Aripiprazole Treatment for Methamphetamine Dependence Among High-risk Individuals NCT00497055 | San Francisco Department of Public Health | Phase 2 |
| Completed | Rivastigmine and Huperzine A as Treatments for Cocaine Dependence NCT01030692 | Baylor College of Medicine | Phase 1 |
| Completed | Study of Medical Treatment for Methamphetamine Addiction NCT00833443 | University of California, Los Angeles | Phase 2 |
| Completed | A SMART Design for Attendance-based Prize CM NCT00840151 | UConn Health | N/A |
| Completed | Health Behaviors in School-age Children: 2009-2010 NCT00797095 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | — |
| Completed | Risk Reduction for Urban Substance Using Men Who Have Sex With Men (MSM) NCT01327898 | Nova Southeastern University | Phase 2 |
| Completed | Contingency Management for Smoking in Substance Abusers NCT00807742 | Brown University | N/A |
| Completed | Women-Focused HIV Prevention in the Western Cape NCT00729391 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 2 / Phase 3 |
| Completed | Healthy Activities for Prize Incentives NCT00717444 | UConn Health | N/A |
| Completed | Transitions: Linkages From Jail To Community NCT00841711 | Yale University | N/A |
| Completed | Efficacy of Dual Focus Mutual Aid for Persons With Co-occurring Disorders NCT01333280 | Western Michigan University | N/A |
| Completed | Enhancing Prevention Capacity With Developmental Assets and Getting to Outcomes NCT00780338 | RAND | Phase 2 |
| Completed | Contingency Management for Cocaine Dependence: Cash Versus Vouchers NCT01366716 | Treatment Research Institute | N/A |
| Completed | Adolescent Substance Abuse: Progressive Treatment NCT00680576 | Oregon Research Institute | Phase 1 |
| Completed | Quetiapine for the Reduction of Cocaine Use NCT00631748 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Withdrawn | Varenicline-Methamphetamine Interaction Study (2008) NCT00733967 | Baylor College of Medicine | Phase 1 |
| Completed | Intervention to Reduce Injection Drug Use NCT00786630 | University of Colorado, Denver | N/A |
| Completed | Regional Anesthesia Military Battlefield Pain Outcomes Study NCT00431847 | VA Office of Research and Development | — |
| Completed | Monitoring and Feedback in Substance Abuse Treatment NCT01465490 | Treatment Research Institute | Phase 1 / Phase 2 |
| Completed | Integrating Interventions for Maternal Substance Abuse NCT01188434 | Oregon Social Learning Center | Phase 1 |
| Completed | Computer-based Brief Intervention for Perinatal Substance Abuse NCT00685074 | Wayne State University | Phase 1 / Phase 2 |
| Completed | An Integrated Substance Abuse-Domestic Violence (SADV) Treatment Outcome Study NCT07140276 | Yale University | N/A |
| Completed | Evaluation of Atomoxetine for Cocaine Dependence: A Pilot Trial NCT00617201 | Sharon Walsh | Phase 2 |
| Completed | Effects of Manualized Treatment in a Seamless System NCT01372033 | George Mason University | Phase 3 |
| Completed | Mirtazapine to Reduce Methamphetamine Use Among MSM With High-risk HIV Behaviors NCT00497081 | San Francisco Department of Public Health | Phase 2 |
| Completed | Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment NCT00288886 | US Department of Veterans Affairs | Phase 2 |
| Completed | Behavior Change and Maintenance Intervention for HIV+ MSM Methamphetamine Users NCT00432926 | University of California, San Diego | Phase 2 |
| Completed | Family-Based Drug Services for Young Disaster Victims NCT01859000 | University of Miami | N/A |
| Completed | Youth Substance Use Prevention/Reduction Through Science-based Drug Abuse Education NCT00612482 | Boston Children's Hospital | Phase 1 |
| Completed | Acupuncture and the Relaxation Response for Substance Abuse NCT00375102 | VA Boston Healthcare System | Phase 2 / Phase 3 |
| Completed | Cognitive Behavioral Treatment of Posttraumatic Stress Disorder Enhanced by Virtual Reality for Individuals Wi NCT00656344 | Weill Medical College of Cornell University | N/A |
| Completed | Acceptability of Pharmacologic Treatment for Methamphetamine Dependence Among MSM NCT00318409 | San Francisco Department of Public Health | Phase 2 |
| Completed | Evaluation of Treatments for Homeless Youths NCT01143792 | Ohio State University | Phase 2 |
| Completed | Psychoeducation for Hepatitis and Alcohol Behaviors NCT00598416 | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | N/A |
| Completed | Implementing School Wide PBS in Middle Schools: The Foundation for Effective Prevention NCT04711681 | University of Oregon | N/A |
| Completed | Group Therapy for Women Prisoners With Comorbid Substance Use and Depression NCT00606996 | Brown University | N/A |
| Completed | Cradling Our Future Through Family Strengthening Study NCT00373750 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Completed | Screening Protocol for the Evaluation of Research Participants NCT01036217 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both NCT00316303 | Dartmouth-Hitchcock Medical Center | Phase 2 |
| Completed | Attention Deficit Hyperactivity Disorder (ADHD) in Adolescents With Substance Use Disorders (SUD) NCT00264797 | University of Cincinnati | Phase 3 |
| Completed | Home Based Treatment for Drug Use in Early Adolescents NCT00280228 | University of Pittsburgh | Phase 2 |
| Completed | CRAFT Behavior Therapy: Treatment Entry Component NCT00842036 | Treatment Research Institute | Phase 2 |
| Completed | Integrating Mindfulness-Based Skills Training Into Brief Outpatient Treatment for Substance Abusing Youth NCT00244699 | Centre for Addiction and Mental Health | N/A |
| Recruiting | Substance Abuse Pre-Treatment Screening Study NCT00439049 | The University of Texas Health Science Center, Houston | — |
| Completed | Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder NCT00399763 | Denver Health and Hospital Authority | N/A |
| Completed | Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use Disorder NCT00130923 | Dartmouth-Hitchcock Medical Center | Phase 4 |
| Completed | Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) NCT00798538 | Yale University | Phase 4 |
| Completed | Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation NCT00484692 | Medical University Innsbruck | Phase 4 |
| Completed | Relapse Prevention for Suicidal Dually Diagnosed Youths NCT00589641 | Duke University | Phase 1 |
| Completed | Group-Based Contingency Management for Substance Abuse Treatment - 1 NCT00249717 | UConn Health | N/A |
| Completed | Abilify Therapy for Reducing Comorbid Substance Abuse NCT00208169 | Creighton University | Phase 4 |
| Terminated | Methylphenidate Studies for Drug Abuse Vulnerability Molecular Genentics NCT00247689 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Brief Interventions for Drop-out Re-engagement NCT00350571 | Yale University | Phase 1 |
| Completed | Registration of Tobacco, Coffee and Substance Use Among Acutely Admitted Psychiatric Patients NCT00184184 | Norwegian University of Science and Technology | — |
| Completed | Low-Cost Contingency Management for Hispanic Outpatients - 3 NCT00249548 | National Institute on Drug Abuse (NIDA) | N/A |
| Completed | Linking Services to Patient Needs for Improved Patient Outcomes (CASPAR) NCT01813864 | Treatment Research Institute | N/A |
| Completed | Brief Strategic Family Therapy for Adolescent Drug Abusers NCT00095303 | University of Miami | Phase 3 |
| Completed | Directly Observed Therapy for Community-Released HIV+ Prisoners NCT00786396 | Yale University | N/A |
| Completed | HIV Prevention Among Substance Abusing SMI NCT00447720 | University of Pennsylvania | Phase 3 |
| Completed | Clinical Trial of Abstinence-Linked Money Management NCT00536900 | Yale University | Phase 2 |
| Completed | Depakote ER Therapy for Mania Comorbid With Substance Abuse NCT00208195 | Creighton University | Phase 4 |
| Completed | Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder NCT00156715 | Dartmouth-Hitchcock Medical Center | Phase 4 |
| Completed | Fetal Alcohol Damage Prevention Study NCT00696085 | Massachusetts General Hospital | N/A |
| Completed | Pregnenolone Trial for Depression in Bipolar Disorders or Recurrent Major Depressive Disorder With Substance A NCT00223197 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | Contingency Management for Attendance - 2 NCT00249639 | National Institute on Drug Abuse (NIDA) | N/A |
| Completed | Divalproex ER vs. Risperidone for Bipolar Disorder With Comorbid Substance Use Disorder NCT00203528 | Tuscaloosa Research & Education Advancement Corporation | Phase 4 |
| Completed | Training Therapists to Administer Contingency Management-Patient Phase - 3 NCT00249418 | UConn Health | N/A |
| Completed | Transitional Treatment of Adolescents in Family Therapy NCT00680381 | Oregon Research Institute | Phase 1 |
| Completed | Therapists to Administer Contingency Management-Therapist Phase - 1 NCT00249626 | UConn Health | N/A |
| Completed | Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia NCT00208143 | Creighton University | Phase 4 |
| Active Not Recruiting | The Community Youth Development Study: A Test of Communities That Care NCT01088542 | University of Washington | N/A |
| Completed | Vouchers vs. Prizes for Methadone Patients - 1 NCT00249522 | National Institute on Drug Abuse (NIDA) | N/A |
| Completed | Reducing Barriers to Drug Abuse Treatment Services NCT00273845 | Wright State University | Phase 2 / Phase 3 |
| Completed | Lower-Cost Contingency Management in a Group Setting - 1 NCT00249600 | UConn Health | N/A |
| Completed | Adolescent Outpatient and Continuing Care Study NCT01381133 | Chestnut Health Systems | Phase 3 |
| Unknown | Trial of Impact of Crime Group Intervention for Jail Inmates NCT01380977 | George Mason University | Phase 1 / Phase 2 |
| Completed | Effectiveness of Advisor-Teller Money Manager NCT00105768 | US Department of Veterans Affairs | Phase 1 / Phase 2 |
| Completed | Family Spirit Study NCT00356551 | Johns Hopkins University | N/A |
| Completed | Directly Observed Antiretroviral Therapy Among Active Drug Users NCT00367172 | Yale University | N/A |
| Completed | Prevention of HIV and STDs in Drug Using Women NCT01235091 | Washington University School of Medicine | N/A |
| Completed | Student Athlete Testing Using Random Notification NCT00451854 | National Institute on Drug Abuse (NIDA) | N/A |
| Terminated | Alcoholism and Schizophrenia: Effects of Clozapine NCT00169026 | Dartmouth-Hitchcock Medical Center | Phase 4 |
| Completed | Relational Parenting Group for Opioid-addicted Mothers NCT00319241 | Yale University | Phase 2 |
| Completed | The Maternal Lifestyle Study (MLS) NCT00059540 | NICHD Neonatal Research Network | — |
| Completed | The Genetic Basis for Vulnerability to Substance Abuse NCT00247819 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Onsite Versus Referral Models of Primary Care for Substance Abusing Patients NCT00057096 | US Department of Veterans Affairs | N/A |