NCT00208195

Depakote ER Therapy for Mania Comorbid With Substance Abuse

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Creighton University · Academic / Other
• Sex: All
• Age: 19 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to ascertain whether Depakote ER (Divalproex ER) has efficacy in the treatment of patients with bipolar disorder in the manic phase, who also have comorbid substance abuse diagnoses. It is proposed that Depakote ER will decrease scores on the Young Mania Rating Scale and the Substance Abuse Time Line Follow Back.

Detailed description

This study will be performed in male and female subjects with a diagnosis of bipolar disorder in the manic phase of the illness who also have a comorbid diagnosis of substance abuse. This population is selected so the efficacy of Depakote ER in this population can be tested.

Conditions

• Bipolar Disorder
• Mania
• Substance Abuse
• Substance Dependence

Interventions

Type	Name	Description
DRUG	Divalproex ER

Timeline

• Start date: 2004-03-01
• Completion: 2007-11-01
• First posted: 2005-09-21
• Last updated: 2007-12-14

Locations

1 site across 1 country: United States