NCT00399763

Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder

A Randomized, Placebo-controlled Trial of Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder (SUD)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Denver Health and Hospital Authority · Academic / Other
• Sex: All
• Age: 12 Years – 19 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to find out whether atomoxetine (also called Strattera) helps teenagers (12-19) with Attention Deficit Hyperactivity Disorder (ADHD) and drug/alcohol problems.

Detailed description

Evidence-based psychosocial treatments have recently been developed. However, very little data exist on the use of pharmacotherapy for adolescents SUD (Substance Use Disorder). One promising pharmacotherapy approach is to treat co-occuring psychiatric disorders. A common co-occurring disorder in adolescent SUD is attention-deficit/hyperactivity disorder (ADHD). Fortunately, new ADHD medications, such as atomoxetine, that do not have addictive potential are now available. However, all controlled studies of atomoxetine have specifically excluded teens with SUD. Therefore, little data exist on the safety and efficacy of the medication in this population. This research project will address the important research gap with the specific aim: to conduct a randomized, placebo-controlled trial of atomoxetine for ADHD in teens with SUD.

Conditions

• Attention Deficit Hyperactivity Disorder
• Substance Abuse

Interventions

Type	Name	Description
DRUG	Atomoxetine	Half of participants are randomized to atomoxetine plus individual cognitive behavioral therapy targeting substance use disorder
DRUG	Placebo	Half of participants are randomized to placebo plus individual cognitive behavioral therapy targeting substance use disorder

Timeline

• Start date: 2005-09-01
• Primary completion: 2008-02-01
• Completion: 2008-02-01
• First posted: 2006-11-15
• Last updated: 2015-07-08
• Results posted: 2015-07-08

Locations

1 site across 1 country: United States