NCT01601743

Exercise as a Behavioral Treatment for Cocaine Dependence

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Baylor College of Medicine · Academic / Other
• Sex: All
• Age: 21 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test the effects of exercise on cocaine use, fitness, and cravings for cocaine and nicotine. This study is part of an effort to develop treatments for cocaine abuse.

Detailed description

This proposal represents an important research effort with considerable public health significance in that it will provide detailed behavioral and physiological data for a non-pharmacological intervention to treat stimulant addiction. Regular exercise is known to promote better mental and physical health, however the effects of exercise on cocaine use and craving in cocaine-dependent individuals has not been previously assessed. The Specific Aims include: 1) To evaluate the effects of regular exercise (running and walking) versus placebo (sitting) on basic fitness measures; 2) To evaluate the effects of exercise on objective and subjective measures of cocaine and nicotine use and craving. Participants will also receive a total of 12 sessions of a standardized series of computerized cognitive behavioral therapy (CCBT) modules, which are specifically designed for the treatment of cocaine addiction.

Conditions

• Cocaine Dependence
• Cocaine Addiction
• Cocaine Abuse
• Substance Abuse

Interventions

Type	Name	Description
BEHAVIORAL	Sitting	Sitting for the same period of time and duration (30 minutes per session, 3 times per week, over 4 consecutive weeks).
BEHAVIORAL	Running	Exercise (running) for 30 minutes per session, 3 times per week, over 4 consecutive weeks.
BEHAVIORAL	Walking	Exercise (walking) for 30 minutes per session, 3 times per week, over 4 consecutive weeks.

Timeline

• Start date: 2011-09-01
• Primary completion: 2014-07-01
• Completion: 2014-07-01
• First posted: 2012-05-18
• Last updated: 2015-01-27

Locations

1 site across 1 country: United States