| Completed | sTMS for Substance Use-disordered Veterans NCT04336293 | VA Office of Research and Development | N/A |
| Terminated | Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients With Cocaine Addiction NCT03423667 | Salvatore Campanella | Phase 2 |
| Completed | Effects of tDCS on Craving, Relapse and Cognitive Functions Among Patients With Cocaine Use Disorder NCT03025321 | Erasmus Medical Center | N/A |
| Unknown | Effect of N-acetylcysteine on Alcohol and Cocaine Use Disorders: A Double-Blind Randomized Controlled Trial. NCT03018236 | Hospital de Clinicas de Porto Alegre | Phase 4 |
| Completed | Dexamphetamine Sustained Release Pharmacokinetics and Clinical Validation of Dried Blood Spots NCT02768441 | The Netherlands Cancer Institute | EARLY_Phase 1 |
| Completed | Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study NCT02563769 | Temple University | Phase 1 |
| Completed | Neurobiological Adaptations and Pharmacological Interventions in Cocaine Addiction NCT02626494 | Psychiatric University Hospital, Zurich | Phase 4 |
| Completed | The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol Cues NCT02939352 | Medical University of South Carolina | EARLY_Phase 1 |
| Unknown | Deep Brain Stimulation of the Sub-Thalamic Nucleus to Treat Severe and Treatment-resistant Cocaine Addiction. NCT02892851 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving NCT01929343 | Bryon Adinoff | Phase 2 |
| Completed | Enhancing Disrupted Reconsolidation: Impact on Cocaine Craving NCT01822587 | Medical University of South Carolina | Phase 2 |
| Completed | Efficacy and Safety of TV-1380 as Treatment for Facilitation of Abstinence in Cocaine-Dependent Subjects NCT01887366 | Teva Branded Pharmaceutical Products R&D, Inc. | Phase 2 |
| Completed | Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence NCT01984177 | Centre for Addiction and Mental Health | — |
| Completed | Pramipexole as a Treatment for Cocaine Dependence NCT01651377 | Baylor College of Medicine | Phase 1 |
| Completed | Exercise as a Behavioral Treatment for Cocaine Dependence NCT01601743 | Baylor College of Medicine | N/A |
| Completed | A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence NCT01651364 | Baylor College of Medicine | Phase 1 |
| Completed | Prefrontal Cortex Stimulation as Treatment for Crack-cocaine Addiction NCT01337297 | Federal University of Espirito Santo | Phase 1 / Phase 2 |
| Unknown | Reducing Drug Craving Memories NCT01319214 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | Vigabatrin for the Treatment of Cocaine Dependency NCT01281202 | Catalyst Pharmaceuticals, Inc. | Phase 2 / Phase 3 |
| Completed | Modafinil - Escitalopram Study for Cocaine Dependence NCT01601730 | Baylor College of Medicine | Phase 1 |
| Completed | Cognitive Enhancement and Relapse Prevention in Cocaine Addiction NCT01067846 | University of Arkansas | N/A |
| Unknown | Effects of Repeated Transcranial Magnetic Stimulation (rTMS) on the Treatment of Cocaine Addicted Patients NCT01259362 | University of Sao Paulo General Hospital | Phase 2 |
| Completed | The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine NCT01062945 | Baylor College of Medicine | Phase 1 |
| Completed | Brain Imaging Study of the Effects of Modafinil in Cocaine Addiction NCT00701532 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Integrative Meditation (IM) for Cocaine Addiction NCT01211418 | University of Maryland, Baltimore | N/A |
| Completed | Rivastigmine and Huperzine A as Treatments for Cocaine Dependence NCT01030692 | Baylor College of Medicine | Phase 1 |
| Completed | Quetiapine for the Reduction of Cocaine Use NCT00631748 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Completed | Vigabatrin Ph 1 Cocaine Interaction Study NCT00626834 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Withdrawn | Psychology of Reward and Punishment: Functional and Molecular Brain Imaging and Monoaminergic Correlates NCT00865332 | National Institute on Drug Abuse (NIDA) | — |
| Completed | A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction NCT00567814 | Embera NeuroTherapeutics, Inc. | N/A |
| Completed | Developing Computer Based Treatments for Addiction NCT00586534 | Duke University | N/A |
| Completed | A Study of the Relationship Between Disulfiram and Cocaine Self-administration. NCT00729300 | Baylor College of Medicine | Phase 1 / Phase 2 |
| Completed | Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Stu NCT00292136 | National Institute on Drug Abuse (NIDA) | — |