Clinical Trials Directory

Trials / Completed

CompletedNCT02768441

Dexamphetamine Sustained Release Pharmacokinetics and Clinical Validation of Dried Blood Spots

Pharmacokinetics of New Dexamphetamine Sustained Release Tablets and the Clinical Validation of Measuring Dexamphetamine in Dried Blood Spots

Status
Completed
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
12 (actual)
Sponsor
The Netherlands Cancer Institute · Academic / Other
Sex
All
Age
25 Years
Healthy volunteers
Not accepted

Summary

The pharmacokinetics of 10 to 12 individuals receiving 60 mg of sustained release dexamphetamine will be studied. These individuals have received this medication before in a previous trial where the pharmacodynamics were investigated. This trial will last 5 consecutive days during which blood samples will be drawn for pharmacokinetics analyses. Dried blood spots will also be collected for the clinical validation of the bioanalytical method wherein these are used.

Conditions

Interventions

TypeNameDescription
DRUGDexamphetamineParticipants will receive 60 mg Dexamphetamine SR daily for 5 consecutive days

Timeline

Start date
2016-11-01
Primary completion
2017-06-01
Completion
2017-06-01
First posted
2016-05-11
Last updated
2017-06-02

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT02768441. Inclusion in this directory is not an endorsement.