Clinical Trials Directory

Trials / Sponsors / The Netherlands Cancer Institute

The Netherlands Cancer Institute

Academic / Other · 227 registered clinical trials56 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingWhole Body HER2 Quantification With 89Zr-Trastuzumab PET/CT to Asses Zr-trastuzumab Accumulation in HER2-mutat
Lung Cancer (NSCLC), HER2 Expression, HER2 Gene Mutation
Phase 12026-08-01
Not Yet RecruitingPembrolizumab Adjuvant in Patients With Early-stage Triple Negative Breast Cancer With Residual Disease After
Triple Negative Breast Cancer (TNBC), Early Setting, Early Stage Triple-Negative Breast Carcinoma, Triple -Negative Breast Cancer
Phase 32026-04-01
RecruitingShort Course of Radiotherapy Prior to Surgery of Soft Tissue Sarcomas
Sarcoma of Soft Tissue, Sarcoma, Sarcoma, Soft Tissue
N/A2025-12-11
RecruitingDose De-escalation in Prostate Radiotherapy Using an MR-Linac in Two Fractions
Prostate Cancer (Adenocarcinoma)
N/A2025-11-17
RecruitingTAO-Towards Optimal (Neo)Adjuvant Systemic Therapy of Stage III Triple-negative Breast Cancer
Breast Cancer
2025-11-06
RecruitingChemosensitivity During Phases of the Menstrual Cycle in Breast Cancer Patients
Breast Cancer
N/A2025-10-14
RecruitingContrast-enhanced Ultrasound for Sentinel Node Detection
Melanoma, Breast Cancer, Head & Neck Cancer
Phase 2 / Phase 32025-09-18
RecruitingTranstympanic STS Against Cisplatin-induced SNHL: the SOUND Trial
Cisplatin-related Hearing Loss
Phase 32025-08-14
RecruitingFunctional Liver After SBRT
Liver Metastases
2025-07-21
RecruitingBevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Nec
Radiation Necrosis, High Grade Glioma (III or IV), Brain Metastasases
Phase 32025-06-19
RecruitingLong-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor
Gastrointenstinal Stromal Tumor (GIST)
2025-05-21
RecruitingTowards Cure Via Only Ultra-short ICB in CSCC
Cutaneous Squamous Cell Carcinoma (CSCC), Cutaneous Squamous Cell Cancer, Cutaneous Squamous Cell Carcinoma of the Head and Neck
Phase 22025-05-14
RecruitingThe PROOV Study: Exploiting the Synergistic Effect of PARP Inhibition With Cisplatin and Hyperthermia During I
Ovarian Cancer, Epithelial Cancer, Fallopian Tube Cancer
Phase 1 / Phase 22025-05-01
RecruitingOPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal
Breast Cancer Stage I, Triple Negative Breast Cancer (TNBC)
2025-04-15
RecruitingWhole Body HER3 Quantification With Radiolabelled Patritumab Deruxtecan (HER3-DXd) PET/CT
Non-Small Cell Lung Carcinoma, Advanced Non-Small Cell Squamous Lung Cancer, EGFR Gene Mutation
Phase 22025-03-03
RecruitingThe Radium-select Study
mCRPC, Male Urogenital Diseases
N/A2025-02-24
RecruitingEarlier Detection and Optimization of Treatment and Prognosis for Patients With Early-onset Colorectal Cancer
Early-onset Colorectal Cancer
2025-01-27
Not Yet RecruitingThe Diagnostic Value of FAPI PET/CT in Staging of Newly Diagnosed Prostate Cancer
Prostate Cancer, Prostate Cancer Metastatic
N/A2024-12-01
RecruitingInduction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion
Colorectal Neoplasms, Floxuridine, Liver Metastases
Phase 32024-11-21
RecruitingCarboplatin/Paclitaxel + Pembrolizumab for Locoregionally Advanced Penile Cancer
Urologic Neoplasms, Urogenital Neoplasms, Male Urogenital Diseases
Phase 22024-08-13
RecruitingFeasibility of Primer Shot Radiotherapy for Non-small Cell Lung Cancer - PRIMER
Patients With Non-small-cell Lung Cancer
N/A2024-08-08
RecruitingAbsorbed Tumor Dose in Peptide Receptor Radionuclide Therapy with Long-acting Somatostatin Analogues - ATSA Tr
Neuroendocrine Tumors, Neuroendocrine Tumor Grade 1, Neuroendocrine Tumor Grade 2
Phase 2 / Phase 32024-06-25
CompletedNavigated Partial Nephrectomy
Renal Cancer, Partial Nephrectomy
N/A2024-06-20
RecruitingLB-100 (PP2A Inhibitor) and Atezolizumab (PD-L1 Inhibitor) in Metastatic Colorectal Cancer Patients
Metastatic Microsatellite-stable Colorectal Cancer
Phase 12024-06-18
RecruitingNOvel Immunotherapy Strategies for Advanced Triple Negative Breast Cancer (TNBC) Patients: TONIC-3 Trial
Metastatic Breast Cancer
Phase 22024-06-12
Not Yet RecruitingDistributed Learning of Edic and CardIac Dose Effects in Lung Cancer
NSCLC
2024-06-01
RecruitingBasket Study for Oligo-metastatic Breast Cancer
HER2-positive Breast Cancer
Phase 22024-05-02
RecruitingPreoperative Accelerated Partial Breast Irradiation in Patients With Locally Recurrent or Second Primary Breas
Breast Cancer
N/A2024-04-12
RecruitingIntradermal Ipilimumab and Nivolumab in High Risk Stage II Melanoma
Melanoma
Phase 1 / Phase 22024-03-08
Active Not RecruitingA Pilot Study of Dose dE-eScalaTion IN prostATe radIOtherapy usiNg the MRL
Prostate Cancer
N/A2024-02-29
RecruitingStage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab
Urologic Neoplasms, Urogenital Neoplasms, Neoplasms by Site
Phase 22024-02-19
CompletedThe Food-effect on Alectinib Pharmacokinetics
NSCLC
N/A2024-02-01
RecruitingPan-tumor Neoadjuvant Basket Study of Immune Check-point Inhibition and Novel Immuno-oncology Combinations
Resectable MMR-deficient Solid Tumors, Resectable MMR-proficient Solid Tumors
Phase 2 / Phase 32024-01-29
RecruitingPEnile ReHABilitation After Nerve Sparing Robot-assisted Radical Prostatectomy for Prostate Cancer 2.0 (PEHAB-
Erectile Dysfunction Following Radical Prostatectomy
Phase 42024-01-15
RecruitingPrimary Chemoradiation VS. Neoadjuvant Chemotherapy Followed By Surgery As Treatment Strategy For LAVC
Locally Advanced Vulvar Carcinoma, Squamous Cell Carcinoma of the Vulva
Phase 22024-01-01
RecruitingNeoadjuvant Trastuzumab, Pertuzumab and Tucatinib Without Chemotherapy in HER2-positive Breast Cancer: the TRA
Breast Cancer
Phase 12023-12-18
UnknownPeri-operative Slow-paced Breathing to Reduce Anxiety in Breast Cancer Surgery Patients
Anxiety
N/A2023-11-29
UnknownRadioembolisation and Chemotherapy in Liver Metastatic Breast Cancer Patients
Liver Metastases, Breast Cancer
N/A2023-10-19
RecruitingFeasibility of CBCT-Guided Online Adaptive Radiotherapy (FASCINATE)
Prostate Cancer, Cervical Cancer, Bladder Cancer
N/A2023-08-29
RecruitingGalunisertib Combined With Capecitabine in Advanced CRC With PM
Colorectal Cancer Metastatic, Peritoneal Carcinomatosis
Phase 1 / Phase 22023-07-28
UnknownSubtherapeutic Dose of Piracetam as a Therapy Adherence Marker
Drug Adherence Marker
Phase 42023-07-03
UnknownEffect of a Bundle of Non-pharmacological Interventions on the Stress Response to Surgery
Surgical Injury, Stress, Physiological, Stress, Psychological
2023-05-01
RecruitingStandard Moderately Hypofractionated RT vs. Ultra-hypofractionated Focal Lesion Ablative Microboost in Prostat
Prostate Cancer
N/A2023-04-26
RecruitingCOntinue the SaMe Systemic Therapy After Local Ablative Therapy for Oligo Progression in Metastatic Breast Can
Breast Cancer Invasive, Metastatic Cancer, Oligoprogressive
Phase 22023-04-17
Unknown'Cancer Patients Better Life Experience'
Melanoma
N/A2023-04-15
UnknownUpfront Resection of Locally Advanced NSCLC Followed by Chemoradiotherapy
Locally Advanced Non-Small Cell Lung Cancer, Chemoradiotherapy, Cavitation Lung
N/A2023-04-01
RecruitingValidation of ICG-99mTc-nanoscan as Hybrid Tracer for Sentinel Node Biopsy
Penile Cancer, Melanoma, Oral Cancer
N/A2023-04-01
UnknownTracer-Guided Surgery for Recurrent Prostate Cancer
Prostate Cancer
Phase 22023-02-15
Active Not RecruitingAnti-PD-1 Re-challenge After Immune Priming by Ipilimumab and Immune Boosting by Radiotherapy in Advanced NSCL
Carcinoma, Non-Small-Cell Lung
Phase 22023-01-03
Active Not RecruitingPembrolizumab for Locally Advanced, Irresectable, Non-metastatic dMMR Colorectal Cancers
Colorectal Cancer
Phase 22022-12-22
RecruitingDESCARTES: De-ESCAlation of RadioTherapy in Patients With Pathologic Complete rESponse to Neoadjuvant Systemic
Breast Cancer
N/A2022-10-07
RecruitingFMT to Convert Response to Immunotherapy
Melanoma Stage III, Melanoma Stage IV
Phase 1 / Phase 22022-08-31
UnknownEffectiveNess of a Multimodal preHAbilitation Program in patieNts With Bladder canCEr Undergoing Cystectomy
Bladder Carcinoma
N/A2022-08-11
TerminatedSarcomas and DDR-Inhibition; a Combined Modality Study
Soft Tissue Sarcoma Adult
Phase 12022-07-18
UnknownFAPI PET/CT for Lymph Node Staging in Colorectal Carcinoma
Colorectal Cancer
N/A2022-07-13
UnknownAssociation of Silicone Breast Implants With Overall Wellbeingand Auto-immune Diseases
Breast Cancer, Breast Implant; Complications, Autoimmune Diseases
2022-07-01
Active Not RecruitingBody Surface Area-based vs Concentration-based Dosing of Cisplatin for Hyperthermic Intraperitoneal Chemothera
FIGO Stage III Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Carcinoma
Phase 22022-06-15
Active Not RecruitingNeoadjuvant Study With Combination Immuno-oncology for Primary Clear Cell Renal Cell Cancer
Renal Cell Carcinoma
Phase 22022-04-28
TerminatedCombination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant Cancers
Pancreatic Cancer, Colorectal Cancer, Non-small Cell Lung Cancer
Phase 12022-03-31
UnknownProspective Clinical Validation of a Novel Multitarget FIT in CRC Screening
CRC, Advanced Neoplasia
2022-03-25
Active Not RecruitingCheckpoint Inhibition and Chemoradiotherapy as Bladder Sparing Treatment in UC
Urothelial Carcinoma, Bladder Cancer
Phase 22022-03-14
WithdrawnCetuxibab to Reduce Circulating Tumor Cells in Early Stage NSCLC
Lung Cancer, Surgery, Circulating Tumor Cell
Phase 22022-01-01
CompletedEBRT + Lu-PSMA for N1M0 Prostate Cancer
Prostatic Neoplasm
Phase 12021-12-20
CompletedVessel- and Bone-based Ultrasound Registration
Abdominal Cancer
N/A2021-12-05
TerminatedImproved Implant for Reconstruction Purposes After Mandibular Resection
Head and Neck Cancer, Oral Cancer
N/A2021-11-29
RecruitingThe Prognostic Role of Lymph Node Dissection In Men With Prostate Cancer Treated With Radical Prostatectomy
Prostate Cancer
N/A2021-11-17
CompletedMultispectral Fluorescence as a Tool to Separate Healthy and Disease Related Lymphatic Anatomies in Prostate C
Prostate Cancer
2021-11-01
CompletedPre-operative Immunotherapy in Stage II-III Urothelial Cancer
Urothelial Carcinoma
Phase 12021-08-23
Active Not RecruitingNeoadjuvant Ipilimumab Plus Nivolumab Versus Standard Adjuvant Nivolumab in Macroscopic Stage III Melanoma
Malignant Melanoma Stage III
Phase 32021-07-08
UnknownImage-guided Navigation During Robotic Sentinel Node Removal
Prostate Cancer
N/A2021-07-01
Active Not RecruitingShort Course Of Preoperative Radiotherapy in Head and Neck-, Trunk- and Extremity Soft Tissue Sarcomas
Soft Tissue Sarcomas
N/A2021-06-25
RecruitingThe Prospective Observational COMPRAYA Cohort Study
Second Cancer, Survivorship, Fertility Issues
2021-06-18
UnknownUltrasound-guided Erector Spinae Plane Block Versus Paravertebral Block in Breast Cancer Patients Undergoing M
Breast Cancer Patients Undergoing Mastectomy With Immediate Reconstruction
N/A2021-06-01
CompletedCYP3A4 Activity in Patients With Prostate Cancer Versus Male Patients With Other Solid Tumours
Prostate Cancer, Solid Tumor, Adult
N/A2021-04-22
RecruitingOrgan Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local E
Organ Preservation, Rectal Cancer, Quality of Life
N/A2021-04-16
UnknownLiquid Biopsies for Improving the Pre-operative Diagnosis of Ovarian Cancer
Ovarian Neoplasms
2021-04-14
CompletedMonalizumab and Trastuzumab In Metastatic HER2-pOSitive breAst Cancer: MIMOSA-trial
Breast Cancer
Phase 22021-03-23
Active Not RecruitingPembrolizumab Plus Lenvatinib In Second Line and Third Line Malignant Pleural mesotheLioma Patients
Mesotheliomas Pleural
Phase 22021-03-01
RecruitingInternational Prospective Registry on Local Treatment Approaches in MLS
Myxoid Liposarcoma
2021-01-18
TerminatedCardiac Changes After Stereotactic Radiotherapy for Early Stage NSCLC Cancer or Lung Metastasis
Lung Cancer Stage I, Lung Cancer Stage II, Lung Metastases
N/A2021-01-13
UnknownHepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)
Colorectal Neoplasms
Phase 2 / Phase 32020-09-09
CompletedNeo-adjuvant T-VEC + Nivolumab Combination Therapy for Resectable Early Metastatic (stage IIIB/C/D-IV M1a) Mel
Melanoma Stage III, Melanoma Stage IV
Phase 22020-09-08
CompletedNeo-adjuvant Nivolumab or Nivolumab With Ipilimumab in Advanced Cutaneous Squamous Cell Carcinoma Prior to Sur
Cutaneous Squamous Cell Carcinoma
Phase 22020-08-11
CompletedTracked Ultrasound for Patient Registration in Surgical Navigation During Abdominal Cancer Surgery
Abdominal Cancer
2020-07-13
UnknownTechnetium Based Radioguided Surgery for Prostate Cancer (TRACE) Study
Prostate Cancer
2020-03-11
RecruitingImmune Induction Strategies to Improve Response to Immune Checkpoint Blockade in Triple Negative Breast Cancer
Metastatic Breast Cancer
Phase 22020-02-21
CompletedDiagnostic Yield of Colonoscopy Surveillance in Testicular Cancer Survivors Treated With Platinum-based Chemot
Testicular Cancer, Colorectal Neoplasms
N/A2020-02-18
CompletedCardiotoxicity and Other Late Effects After Radiotherapy and Immuno-chemoTherapy in Non-Hodgkin lYmphoma
Non Hodgkin Lymphoma, DLBCL, Cardiovascular Diseases
2020-02-01
RecruitingTreatment of Metastatic Vulvar Carcinoma With Carboplatin and Paclitaxel Chemotherapy
Metastatic Squamous Cell Carcinoma of the Vulva
Phase 22020-01-16
UnknownImproving the Safety of Fluoropyrimidine-based Chemotherapy
Neoplasms
N/A2020-01-15
RecruitingTreatment of Locally Advanced VULvar CArcinoma in a Neoadjuvant Setting With Carboplatin and Paclitaxel Chemot
Locally Advanced, Squamous Cell Carcinoma of the Vulva
Phase 22020-01-14
CompletedMulticenter Phase 1b Trial Testing the Neoadjuvant Combination of Domatinostat, Nivolumab and Ipilimumab in IF
Malignant Melanoma Stage III
Phase 1 / Phase 22020-01-07
Active Not RecruitingPrimary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Ovarian Cancer
Phase 32020-01-01
WithdrawnLY3200882 and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer (EORTC1615)
Colorectal Cancer Metastatic
Phase 1 / Phase 22020-01-01
Not Yet RecruitingAvoiding Sentinel Lymph Node Biopsy in Breast Cancer Patients After Neoadjuvant Chemotherapy
Breast Cancer, Triple Negative Breast Cancer, HER2-positive Breast Cancer
N/A2020-01-01
CompletedPropranolol in Angiosarcoma
Angiosarcoma
Phase 22019-12-27
RecruitingNovel Ga68-PSMA PET/CT-tracer to Differentiate Between Radiation Necrosis and Tumor Progression in Brain Metas
Brain Metastases From Non-small Cell Lung Cancer (NSCLC), Brain Metastases From Melanoma, Brain Metastases From Breast Cancer
N/A2019-12-24
Active Not RecruitingThe SONImage Study
Breast Cancer
N/A2019-12-05
CompletedINtra-operative Evaluation of a Novel FLUorescENt C-mEt Tracer in Penile and Tongue
Head and Neck Cancer, Penile Cancer
2019-11-13
UnknownDedicated MR Imaging vs Surgical Staging of Peritoneal Carcinomatosis in Colorectal Cancer
Colorectal Cancer, Peritoneal Carcinomatosis, MRI
N/A2019-10-28
Active Not RecruitingNeoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN)
Rectal Cancer
Phase 22019-10-22
RecruitingPre-operative Trial for Breast Cancer With Nivolumab in Combination With Novel IO
Breast Cancer
Phase 22019-10-04
UnknownOsimertinib Resistance in Patients With Non-small-cell Lung Carcinoma That Have Progressed.
Non-small-cell Lung Carcinoma
N/A2019-08-22
UnknownInternet-based WOrk-related Cognitive Rehabilitation for Cancer Survivors: a Randomized Controlled Trial
Cognitive Problems
N/A2019-08-03
Active Not RecruitingLymph Drainage Mapping for Tailoring Elective Nodal Irradiation in Head and Neck Cancer
Head and Neck Cancer
N/A2019-07-22
CompletedctDNA Guided Treatment of Early Resistance to Targeted Treatment
Carcinoma, Non-Small-Cell Lung
N/A2019-07-17
CompletedHealth-related Quality of Life and Late Effects Among SURVivors of Cancer in Adolescence and Young Adulthood:
Quality of Life, Late Effect, Survivorship
2019-05-01
UnknownAssessing Health-related Quality of Life in Sarcoma Patients
Sarcoma
2019-05-01
CompletedImprove Checkpoint-blockade Response in Advanced Urothelial Cancer
Urothelial Carcinoma
Phase 1 / Phase 22019-05-01
UnknownHealth After eaRly Menopause Due to Oophorectomy
Surgical Menopause, BRCA1 Mutation, BRCA2 Mutation
2019-02-11
RecruitingBlood Sampling of Healthy Volunteers for Immunological Research
Healthy Volunteers
N/A2019-02-05
RecruitingThe MR-Linac Technical Feasibility Protocol
Tumors at All Sites Which Will Receive Radiotherapy
N/A2019-01-22
TerminatedAssess the Safety of Immunotherapy Induction With Tremelimumab and Durvalumab Prior to Chemoradiotherapy and/o
Stage III NSCLC
Phase 12018-12-28
TerminatedT-DM1 and Osimertinib Combination Treatment to Target HER2 Bypass Track Resistance in EGFR Mutation Positive N
Carcinoma, Non-Small-Cell Lung
Phase 22018-12-18
CompletedAfatinib and Cetuximab in Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Positive Non-small-cell Lu
Carcinoma, Non-Small-Cell Lung
Phase 22018-12-04
TerminatedNeo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve Fertility
Cervical Cancer
Phase 22018-11-01
Completed18F-PD-L1 PET/CT in Nivolumab Treated Patients With NSCLC
NSCLC Stage IV
N/A2018-10-25
CompletedPEnile Cancer Radio- and Immunotherapy CLinical Exploration Study
Penile Cancer
Phase 22018-09-25
UnknownSentinel Lymph Node Procedure in Testicular Germ Cell Tumour
Testicular Germ Cell Tumor
2018-09-01
WithdrawnGalunisertib and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer
Colorectal Cancer Metastatic
Phase 1 / Phase 22018-08-24
CompletedctDNA as a Biomarker for Treatment Response in HNSCC
Carcinoma, Squamous Cell of Head and Neck
N/A2018-07-16
TerminatedA Feasibility Study of Niraparib for Advanced, BRCA1-like, HER2-negative Breast Cancer Patients
Breast Cancer
Phase 22018-05-15
UnknownClinical Impact of Dedicated MR Staging of Ovarian Cancer
Ovarian Cancer
N/A2018-04-13
UnknownNeoadjuvant AXITINIB and AVELUMAB for Patients With Localized Clear-cell RCC
Renal Cell Carcinoma
Phase 22018-03-28
TerminatedPreoperative Breast Irradiation
Breast Cancer
N/A2018-03-12
Active Not RecruitingNeoadjuvant Capecitabine, Oxaliplatin, Docetaxel and Atezolizumab in Resectable Gastric and GE-junction Cancer
Stomach Cancer, Gastro Esophageal Junction Cancer
Phase 22018-03-07
CompletedVinorelbine in Advanced BRAF-like Colon Cancer
Colon Cancer
Phase 22018-03-01
TerminatedEarly Response Evaluation in NSCLC Patients Treated With Immunotherapy
NSCLC, Stage IV
N/A2018-01-23
CompletedNeo-Adjuvant Bladder Urothelial Carcinoma COmbination-immunotherapy
Urothelial Carcinoma
Phase 12018-01-15
TerminatedMonitoring MRI Changes Before and During Radiotherapy Treatment of Brain Tumors
Brain Tumor
2018-01-12
CompletedAdaptive Dose-Escalated Multi-modality Image-guided RadiothErapy
Head and Neck Cancer
N/A2017-12-21
Active Not RecruitingMulticentric Randomised Trial for Resectable Gastric Cancer
Gastric Cancer
Phase 22017-12-21
CompletedDose-Effect Relation of Salivary Gland Irradiation
HNSCC
2017-11-21
TerminatedAssessinG Efficacy of Carboplatin and ATezOlizumab in Metastatic Lobular Breast Cancer
Breast Cancer
Phase 22017-11-02
CompletedNeo-adjuvant Pembrolizumab in Primary Stage IV Ovarian Cancer
Ovarian Cancer Stage IV, Peritoneal Cancer, Fallopian Tube Cancer
Phase 1 / Phase 22017-11-01
WithdrawnCombination of Platinum Doublets and Hypofractionated Radiotherapy in NSCLC
Non-Small Cell Lung Cancer
Phase 22017-11-01
Active Not RecruitingGastrectomy + Cytoreductive Surgery + HIPEC for Gastric Cancer With Peritoneal Dissemination.
Stomach Neoplasm, Peritoneal Carcinomatosis
Phase 32017-10-01
CompletedTo Decrease Fatigue With Light Therapy
Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma
Phase 32017-09-20
RecruitingA Platform of Patient Derived Xenografts (PDX) and 2D/3D Cell Cultures of Soft Tissue Sarcomas (STS)
Soft Tissue Sarcoma, Xenograft Model, 2D/3D Cell Cultures
N/A2017-09-09
CompletedThe Impact of a Web-based Patient Decision Aid for Women Considering Breast Reconstruction
Breast Cancer
N/A2017-08-16
Recruiting"Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer
Rectal Neoplasms
2017-05-10
CompletedOptimal Sequencing of Treatment Options for Poor Risk mCRPC Previously Treated With Docetaxel
Prostate Cancer Metastatic, Metastasis
Phase 2 / Phase 32017-05-07
RecruitingNeoadjuvant Immune Checkpoint Inhibition and Novel IO Combinations in Early-stage Colon Cancer
Colon Carcinoma
Phase 22017-03-29
CompletedImmunoModulation by the Combination of Ipilimumab and Nivolumab Neoadjuvant to Surgery In Advanced or Recurren
Immunotherapy, Head and Neck Neoplasms
Phase 1 / Phase 22017-02-28
Active Not RecruitingManagement of Low-risk (Grade I and II) DCIS
DCIS
N/A2017-02-13
CompletedBioimmunoradiotherapy (Cetuximab/RT/Avelumab)
Carcinoma, Squamous Cell of Head and Neck
Phase 12017-02-01
Active Not RecruitingSubstantially Improving the Cure Rate of High-risk BRCA1-like Breast Cancer
Breast Cancer
Phase 32017-01-25
CompletedNavigated Abdominal Lymph Node Dissections
Image-guide Surgery, Lymph Node Metastasis
N/A2017-01-24
CompletedCarboplatin-cyclophosphamide Combined With Atezolizumab
Breast Cancer, Cervix Cancer, Ovarian Cancer
Phase 12017-01-01
UnknownStudy to Identify the Optimal Adjuvant Combination Scheme of Ipilimumab and Nivolumab in Melanoma Patients
Stage III Skin Melanoma
Phase 12016-11-24
UnknownOptimal Neo-adjuvant Combination Scheme of Ipilimumab and Nivolumab
Malignant Melanoma Stage III
Phase 22016-11-24
TerminatedPre- Versus Postoperative Accelerated Partial Breast Irradiation
Breast Cancer, Cancer of the Breast, Neoplasms, Breast
N/A2016-11-10
CompletedDexamphetamine Sustained Release Pharmacokinetics and Clinical Validation of Dried Blood Spots
Cocaine Addiction
EARLY_Phase 12016-11-01
UnknownThe Effectiveness of Patient Navigation in Cancer Care
Cancer
N/A2016-10-15
TerminatedDocetaxel Versus Intercalated Erlotinib-docetaxel in Patients With Relapsed EGFR Wild Type, ALK Negative Non S
Carcinoma, Non-small Cell Lung
Phase 32016-10-14
CompletedStudy With Improved Solubility Pazopanib
Pharmacokinetics of Pazopanib
EARLY_Phase 12016-09-15
TerminatedOral Docetaxel (ModraDoc/r) in Combination With Hormonal Treatment and Radiation Therapy in High-risk Prostate
Prostatic Neoplasms
Phase 12016-09-01
CompletedThe Development of a Personalized Decision Aid: Perspectives of Patients and Health Care Professionals on Shar
Breast Cancer
2016-09-01
CompletedIpilimumab and Nivolumab in the Treatment of Malignant Pleural Mesothelioma
Malignant Pleural Mesothelioma
Phase 22016-09-01
RecruitingThe Drug Rediscovery Protocol (DRUP Trial)
Cancer, Tumors, Neoplasm
Phase 22016-08-01
CompletedHDAC Inhibitor Vorinostat in Resistant BRAF V600 Mutated Advanced Melanoma
Melanoma, Skin Neoplasms
Phase 1 / Phase 22016-06-01
UnknownLung Cancer Early Molecular Assessment Trial
Carcinoma, Non-Small-Cell Lung
2016-06-01
CompletedFood-effect Study on Uracil and Dihydrouracil Levels as a Diagnostic Marker of Dihydropyrimidine Dehydrogenase
Drug Safety Biomarkers
N/A2016-04-14
UnknownCisplatin-Pemetrexed Compared With Carboplatin-Paclitaxel-Bevacizumab in KRAS Mutated Non-small Cell Lung Canc
Carcinoma, Non-Small Cell Lung
Phase 32016-04-01
UnknownCisplatinum and Everolimus in Patients With Metastatic or Unresectable NEC of Extrapulmonary Origin
Neuroendocrine Carcinomas
Phase 22016-03-30
TerminatedClinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients
Sarcoma, Soft Tissue Sarcomas
Phase 22016-03-17
UnknownStudy Comparing Pembrolizumab With Dual MAPK Pathway Inhibition Plus Pembrolizumab in Melanoma Patients
Metastatic Melanoma
Phase 22016-01-01
TerminatedComparing Two Palliative Schemes of Radiotherapy for Head and Neck Cancer
Head and Neck Neoplasms
N/A2015-11-01
CompletedTreatment Outcomes in a Non-study Population of Symptomatic mCRPC Patients Treated With Radium-223
Prostate Cancer Metastatic, Bone Metastases
2015-10-30
CompletedMolecular Stool Testing for Colorectal Cancer Surveillance
Colorectal Cancer
2015-10-01
UnknownNivolumab After Induction Treatment in Triple-negative Breast Cancer (TNBC) Patients
Breast Cancer
Phase 22015-08-01
CompletedMapping of Sentinel Lymph Node Drainage Using SPECT (SUSPECT) (SUSPECT)
Head and Neck Cancer
N/A2015-07-23
CompletedPembrolizumab After SBRT Versus Pembrolizumab Alone in Advanced NSCLC
Non-Small Cell Lung Cancer
Phase 22015-07-01
CompletedNivolumab in Patients With Recurrent Malignant Mesothelioma
Malignant Pleural Mesothelioma
Phase 22015-07-01
UnknownAfatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer
Colorectal Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms
Phase 1 / Phase 22015-06-01
CompletedPhase I of Carboplatin-Olaparib Followed by Olaparib Monotherapy in Advanced Cancer
Breast Cancer, Ovarian Cancer, Advanced Cancer
Phase 12015-05-01
UnknownIdentifying Subgroups With High Cardiovascular Risk in Breast Cancer Survivors
Breast Neoplasms, Cardiovascular Diseases
2015-04-01
CompletedSafety, Feasibility and Cost-effectiveness of Genotype-directed Individualized Dosing of Fluoropyrimidines
Neoplasms
N/A2015-03-01
CompletedInternet-based Cognitive Behavioral Therapy for Breast Cancer Patients With Climacteric Symptoms
Climacteric Symptoms, Breast Cancer Survivors
Phase 32015-02-01
CompletedRegistry of Treatment Outcomes of Symptomatic Metastasized Castration Resistant Prostate Cancer Treated With R
Prostate Cancer Metastatic, Bone Metastases
2015-01-17
CompletedClinical Trial to Evaluate the Safety and Effectiveness of GDC-0032 When Given Alongside Tamoxifen
Breast Cancer
Phase 1 / Phase 22014-11-01
CompletedLapatinib Plus Trametinib in KRAS Mutant NSCLC
Colorectal Cancer
Phase 1 / Phase 22014-10-07
UnknownOlaparib and Radiotherapy in Head and Neck Cancer
Laryngeal Cancer Stage II, Laryngeal Cancer Stage III, Carcinoma, Squamous Cell
Phase 12014-09-24
CompletedStudy Comparing TIL to Standard Ipilimumab in Patients With Metastatic Melanoma
Metastatic Melanoma
Phase 32014-09-23
UnknownAn International Study on the Use of PET/CT in Radiotherapy Planning in Low and Middle Income Countries
Non Small Cell Lung Cancer Stage III
2014-09-01
Active Not RecruitingHigh Dose Chemotherapy in Oligo-metastatic Homologous Recombination Deficient Breast Cancer
Breast Cancer
Phase 32014-09-01
CompletedDynamics of Androgen Receptor Genomics and Transcriptomics After Neoadjuvant Androgen Ablation
Prostate Cancer, DNA, Androgen Receptor Abnormal
Phase 22014-08-28
Completed4D FDG PET in Esophageal Cancer
Esophageal Cancer
N/A2014-08-01
CompletedOrgan Motion and Early Tumor Response Measurement
Esophageal Cancer, Chemoradiation
2014-04-18
CompletedDacomitinib Plus PD-0325901 in Advanced KRAS Mutant NSCLC
Colorectal Cancer
Phase 1 / Phase 22014-04-02
Active Not RecruitingNeoadjuvant Chemotherapy in HER2 Positive Breast Cancer, TRAIN-2
Breast Cancer, HER2 Positive
Phase 32013-12-01
CompletedOlaparib and Radiotherapy in Inoperable Breast Cancer
Locally Advanced Malignant Neoplasm, Inflammatory Breast Carcinoma, Triple-Negative Invasive Breast Carcinoma
Phase 12013-10-21
UnknownClinical and Pharmacological Study With 2B3-101 in Patients With Breast Cancer and Leptomeningeal Metastases
Meningeal Carcinomatosis
Phase 22013-10-01
Active Not RecruitingTriple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treat
Breast Cancer
Phase 22013-07-01
CompletedHippocampus Avoidance PCI vs PCI
Small Cell Lung Cancer, Lung Cancer
Phase 32013-04-01
CompletedPET Response During Chemoradiation of Lung Cancer
NSCLC
N/A2013-03-21
CompletedCombined CFRT and SABR in Stage II and III NSCLC With Peripheral Tumors Smaller Than 5 cm.
Inoperable Locally Advanced Non Small Cell Lung Cancer
Phase 12013-02-28
CompletedRCT of an Internet-based CBT Program for Sexuality and Intimacy Problems in Women Treated for Breast Cancer
Sexual Dysfunction, Intimacy Problems, Breast Cancer Survivors
Phase 32012-12-01
CompletedAdaptive Radiation Treatment for Head and Neck Cancer
Head and Neck Cancer
Phase 32012-09-07
CompletedCirculating Tumor Cells and Cytology in Cerebrospinal Fluid of Patients Clinically Suspected for Leptomeningea
Meningeal Carcinomatosis
N/A2012-09-01
UnknownPET Evaluation of Recurrent Differentiated Thyroid Cancer
Thyroid Neoplasms, Differentiated Thyroid Cancer
2012-08-01
UnknownProspective Pilot Study ANDPrecise
Breast Cancer
Phase 32012-06-01
CompletedOlaparib Dose Escalating Trial + Concurrent RT With or Without Cisplatin in Locally Advanced NSCLC
NSCLC
Phase 12012-04-01
UnknownStudy With T-cel Receptor Gene Therapy in Metastatic Melanoma
Stage IV Skin Melanoma, Eye; Melanoma
Phase 1 / Phase 22012-03-01
CompletedIrradiation of Large Lung Tumors or Two or More Lung Metastases Simultaneously
Lung Cancer, Metastatic Lung Cancer
Phase 1 / Phase 22011-11-22
CompletedThe Signal-Trial: Evaluation of a Screening Tool for Psychosocial Problems in Cancer Genetics
Psychosocial Issues, Cancer Genetics
N/A2011-10-01
CompletedUse of Individual Pharmacokinetically (PK)-Guided Sunitinib Dosing: A Feasibility Study in Patients With Advan
Malignant Solid Tumour
Phase 12011-04-11
UnknownDocetaxel, Oxaliplatin, Capecitabine, Bevacizumab and Trastuzumab in Patients With Locally Advanced or Metasta
Metastatic Gastric Cancer, Adenocarcinoma of the Gastro-oesophageal Junction
Phase 22011-03-01
UnknownDose Reduction of Preoperative Radiotherapy in Myxoid Liposarcomas
Myxoid Liposarcoma of Soft Tissue
Phase 22010-12-15
CompletedWeekly Administration of (bi-)Daily Oral Docetaxel in Combination With Ritonavir
Cancer
Phase 12010-09-01
CompletedStudy With Wee-1 Inhibitor AZD1775 (MK-1775) and Carboplatin to Treat p53 Mutated Refractory and Resistant Ova
Epithelial Ovarian Cancer
Phase 22010-07-01
CompletedCombined Modality Treatment of Sarcomas of the Extremities
Sarcoma,Soft Tissue
Phase 12010-06-01
UnknownDose Escalation by Boosting Radiation Dose Within the Primary Tumor Using FDG-PET-CT Scan in Stage IB, II and
NSCLC
N/A2010-05-01
Active Not RecruitingNeo Adjuvant Chemotherapy in Triple Negative Breast Cancer
Breast Cancer
Phase 2 / Phase 32010-01-01
CompletedRadiation Therapy Followed by Surgery in Treating Patients With Early-Stage Breast Cancer
Breast Cancer
N/A2009-10-01
CompletedStandard Chemotherapy With of Without Axitinib in Malignant Mesothelioma
Malignant Pleural Mesothelioma
Phase 1 / Phase 22009-05-22
CompletedEffects of Rapid Genetic Counseling and Testing in Newly Diagnosed Breast Cancer Patients
Breast Neoplasms
N/A2008-11-01
CompletedTrastuzumab in a Neo-adjuvant Regimen for HER2+ Breast Cancer - the TRAIN Study
Breast Cancer, HER2 Positive
Phase 22008-09-01
SuspendedPre-operative Hormonal Treatment for Hormone Receptor Positive Breast Cancer
Breast Cancer
Phase 22008-07-01
TerminatedSecond-line Endocrine Treatment Followed by Capecitabine Versus Capecitabine Followed by Endocrine Treatment i
Breast Cancer
Phase 2 / Phase 32008-04-01
UnknownCognitive Behavioral Therapy (CBT) and Physical Exercise for Climacteric Symptoms in Breast Cancer Patients Ex
Menopausal Symptoms in Breast Cancer Patients With Treatment-Induced Complaints
Phase 32008-01-01
CompletedEvaluating the Effect of Candesartan vs Placebo in Prevention of Trastuzumab-associated Cardiotoxicity
Breast Cancer
Phase 32007-06-01
TerminatedIntensified IAA With PBPC Support in Breast Tumors With Evidence of a HRD
Breast Cancer
Phase 2 / Phase 32007-05-01
CompletedPharmacogenomic and Pharmacokinetic Safety and Cost-saving Analysis in Patients Treated With Fluoropyrimidines
Neoplasms
Phase 12007-05-01
CompletedSecondary Debulking Surgery +/- Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer
Ovarian Cancer
Phase 32007-02-01
UnknownRadiation Dose Intensity Study in Breast Cancer in Young Women
Breast Cancer
Phase 32004-07-01
CompletedRadiotherapy for Prostate Cancer: Conventional Dose Versus High Dose
Prostatic Neoplasms
Phase 31997-06-01